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(Lond., Engl.)"},{"key":"10.1016\/j.bbcan.2025.189317_bb0445","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/s41420-025-02289-z","article-title":"Helicobacter pylori reduces METTL14-mediated VAMP3 m(6)A modification and promotes the development of gastric cancer by regulating LC3C-mediated c-Met recycling","volume":"11","author":"Cui","year":"2025","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.bbcan.2025.189317_bb0450","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1038\/s41388-024-03085-2","article-title":"METTL3-mediated N(6)-methyladenosine modification of STAT5A promotes gastric cancer progression by regulating KLF4","volume":"43","author":"Zang","year":"2024","journal-title":"Oncogene"},{"key":"10.1016\/j.bbcan.2025.189317_bb0455","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1038\/s41467-021-21744-w","article-title":"Hyocholic acid species as novel biomarkers for metabolic disorders","volume":"12","author":"Zheng","year":"2021","journal-title":"Nat. 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Res."},{"key":"10.1016\/j.bbcan.2025.189317_bb0475","first-page":"C762","article-title":"The N(6)-methyladenosine (m(6)A)-forming enzyme METTL3 facilitates M1 macrophage polarization through the methylation of STAT1 mRNA","volume":"317","author":"Liu","year":"2019","journal-title":"Am. J. Phys. Cell Phys."},{"key":"10.1016\/j.bbcan.2025.189317_bb0480","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1186\/s12943-022-01634-5","article-title":"The role, mechanism, and application of RNA methyltransferase METTL14 in gastrointestinal cancer","volume":"21","author":"Shi","year":"2022","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.bbcan.2025.189317_bb0485","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.scib.2023.11.029","article-title":"Mettl3-dependent m(6)A modification is essential for effector differentiation and memory formation of CD8(+) T cells","volume":"69","author":"Guo","year":"2024","journal-title":"Sci. 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Rev."},{"key":"10.1016\/j.bbcan.2025.189317_bb0520","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1038\/s41467-020-15126-x","article-title":"Impact of the gut microbiota on the m(6)A epitranscriptome of mouse cecum and liver","volume":"11","author":"Jabs","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbcan.2025.189317_bb0525","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2024.114079","article-title":"The microbiota drives diurnal rhythms in tryptophan metabolism in the stressed gut","volume":"43","author":"Gheorghe","year":"2024","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbcan.2025.189317_bb0530","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1016\/j.celrep.2018.10.068","article-title":"Circadian clock regulation of hepatic lipid metabolism by modulation of m(6)A mRNA methylation","volume":"25","author":"Zhong","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbcan.2025.189317_bb0535","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/nrm.2016.132","article-title":"Post-transcriptional gene regulation by mRNA modifications","volume":"18","author":"Zhao","year":"2017","journal-title":"Nat. Rev. Mol. 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Exp. Clin. Cancer Res."},{"key":"10.1016\/j.bbcan.2025.189317_bb0570","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1186\/s40364-024-00652-3","article-title":"METTL protein family: focusing on the occurrence, progression and treatment of cancer","volume":"12","author":"Zhang","year":"2024","journal-title":"Biomark. Res."},{"key":"10.1016\/j.bbcan.2025.189317_bb0575","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2023.2293312","article-title":"Akkermansia muciniphila protects the intestine from irradiation-induced injury by secretion of propionic acid","volume":"15","author":"He","year":"2023","journal-title":"Gut Microbes"},{"key":"10.1016\/j.bbcan.2025.189317_bb0580","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s13045-022-01224-4","article-title":"RNA demethylase ALKBH5 in cancer: from mechanisms to therapeutic potential","volume":"15","author":"Qu","year":"2022","journal-title":"J. Hematol. Oncol."},{"key":"10.1016\/j.bbcan.2025.189317_bb0585","doi-asserted-by":"crossref","first-page":"5546","DOI":"10.1158\/1078-0432.CCR-12-0977","article-title":"c-Myc and cancer metabolism","volume":"18","author":"Miller","year":"2012","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.bbcan.2025.189317_bb0590","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.cmet.2024.10.003","article-title":"Gut microbiota regulates stress responsivity via the circadian system","volume":"37","author":"Tofani","year":"2025","journal-title":"Cell Metab."},{"key":"10.1016\/j.bbcan.2025.189317_bb0595","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s00018-022-04129-0","article-title":"METTL3 promotes oxaliplatin resistance of gastric cancer CD133+stem cells by promoting PARP1 mRNA stability","volume":"79","author":"Li","year":"2022","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bbcan.2025.189317_bb0600","doi-asserted-by":"crossref","first-page":"4247","DOI":"10.7150\/thno.86528","article-title":"Regulatory mechanisms and therapeutic implications of insulin-like growth factor 2 mRNA-binding proteins, the emerging crucial m(6)A regulators of tumors","volume":"13","author":"Zhou","year":"2023","journal-title":"Theranostics"},{"key":"10.1016\/j.bbcan.2025.189317_bb0605","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1158\/0008-5472.CAN-18-2965","article-title":"The critical role of RNA m(6)A methylation in cancer","volume":"79","author":"Lan","year":"2019","journal-title":"Cancer Res."},{"key":"10.1016\/j.bbcan.2025.189317_bb0610","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.ccell.2020.04.017","article-title":"Targeting FTO suppresses cancer stem cell maintenance and immune evasion","volume":"38","author":"Su","year":"2020","journal-title":"Cancer Cell"},{"key":"10.1016\/j.bbcan.2025.189317_bb0615","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1038\/s41420-022-01286-w","article-title":"ALKBH5 promotes PD-L1-mediated immune escape through m6A modification of ZDHHC3 in glioma","volume":"8","author":"Tang","year":"2022","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.bbcan.2025.189317_bb0620","doi-asserted-by":"crossref","first-page":"4802","DOI":"10.7150\/thno.73746","article-title":"N(6)-methyladenosine-mediated LDHA induction potentiates chemoresistance of colorectal cancer cells through metabolic reprogramming","volume":"12","author":"Zhang","year":"2022","journal-title":"Theranostics"},{"key":"10.1016\/j.bbcan.2025.189317_bb0625","doi-asserted-by":"crossref","first-page":"8319","DOI":"10.1080\/10408398.2021.1927975","article-title":"Could partial nonstarch polysaccharides ameliorate cancer by altering m(6)A RNA methylation in hosts through intestinal microbiota?","volume":"62","author":"Luo","year":"2022","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.bbcan.2025.189317_bb0630","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2023.2249143","article-title":"Microbial metabolite butyrate promotes anti-PD-1 antitumor efficacy by modulating T cell receptor signaling of cytotoxic CD8 T cell","volume":"15","author":"Zhu","year":"2023","journal-title":"Gut Microbes"},{"key":"10.1016\/j.bbcan.2025.189317_bb0635","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.jare.2023.08.014","article-title":"Intracellular Fusobacterium nucleatum infection increases METTL3-mediated m6A methylation to promote the metastasis of esophageal squamous cell carcinoma","volume":"61","author":"Guo","year":"2024","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.bbcan.2025.189317_bb0640","doi-asserted-by":"crossref","first-page":"4343","DOI":"10.1038\/s41467-024-48661-y","article-title":"Prodrug-conjugated tumor-seeking commensals for targeted cancer therapy","volume":"15","author":"Shen","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbcan.2025.189317_bb0645","article-title":"Site-specific m(6) A erasing via conditionally stabilized CRISPR-Cas13b editor","volume":"62","author":"Xu","year":"2023","journal-title":"Angew. Chem. Int. Ed. Eng."},{"key":"10.1016\/j.bbcan.2025.189317_bb0650","doi-asserted-by":"crossref","first-page":"3432","DOI":"10.1038\/s41467-022-31171-0","article-title":"Programmable probiotics modulate inflammation and gut microbiota for inflammatory bowel disease treatment after effective oral delivery","volume":"13","author":"Zhou","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbcan.2025.189317_bb0655","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1126\/science.aao3290","article-title":"The commensal microbiome is associated with anti-PD-1 efficacy in metastatic melanoma patients","volume":"359","author":"Matson","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.bbcan.2025.189317_bb0660","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1126\/science.aal5240","article-title":"Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer","volume":"358","author":"Bullman","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.bbcan.2025.189317_bb0665","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1038\/s41467-020-15508-1","article-title":"Developing a new class of engineered live bacterial therapeutics to treat human diseases","volume":"11","author":"Charbonneau","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbcan.2025.189317_bb0670","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/s41568-021-00378-6","article-title":"Cancer metabolism: looking forward","volume":"21","author":"Mart\u00ednez-Reyes","year":"2021","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.bbcan.2025.189317_bb0675","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1038\/nchembio.1432","article-title":"A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation","volume":"10","author":"Liu","year":"2014","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.bbcan.2025.189317_bb0680","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/s41586-019-0916-x","article-title":"Anti-tumour immunity controlled through mRNA m(6)A methylation and YTHDF1 in dendritic cells","volume":"566","author":"Han","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.bbcan.2025.189317_bb0685","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s12943-022-01508-w","article-title":"Insights into N6-methyladenosine and programmed cell death in cancer","volume":"21","author":"Liu","year":"2022","journal-title":"Mol. 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