{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T02:31:57Z","timestamp":1789612317894,"version":"build-2803163510"},"reference-count":69,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T00:00:00Z","timestamp":1764806400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32270566"],"award-info":[{"award-number":["32270566"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2025JC-GXPT-043"],"award-info":[{"award-number":["2025JC-GXPT-043"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Reviews on Cancer"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.bbcan.2025.189506","type":"journal-article","created":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T07:54:45Z","timestamp":1764834885000},"page":"189506","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Targeting MAO offers a novel immunotherapeutic strategy for prostate cancer by modulating the \u201ctumor-stroma-immune\u201d interaction network"],"prefix":"10.1016","volume":"1881","author":[{"given":"Yaohua","family":"Hu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhite","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifan","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinglin","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changhong","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.bbcan.2025.189506_bb0005","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1186\/s12964-024-01584-z","article-title":"The protein composition of exosomes released by prostate cancer cells is distinctly regulated by androgen receptor-antagonists and -agonist to stimulate growth of target cells","volume":"22","author":"Atri Roozbahani","year":"2024","journal-title":"Cell Commun. Signal"},{"key":"10.1016\/j.bbcan.2025.189506_bb0010","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.semcancer.2021.11.001","article-title":"Understanding and targeting prostate cancer cell heterogeneity and plasticity","volume":"82","author":"Tang","year":"2022","journal-title":"Semin. Cancer Biol."},{"issue":"11","key":"10.1016\/j.bbcan.2025.189506_bb0015","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.neo.2020.09.002","article-title":"Development and prevalence of castration-resistant prostate cancer subtypes","volume":"22","author":"Vellky","year":"2020","journal-title":"Neoplasia"},{"issue":"5","key":"10.1016\/j.bbcan.2025.189506_bb0020","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/nrurol.2018.22","article-title":"Cellular plasticity and the neuroendocrine phenotype in prostate cancer","volume":"15","author":"Davies","year":"2018","journal-title":"Nat. Rev. Urol."},{"issue":"22","key":"10.1016\/j.bbcan.2025.189506_bb0025","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1038\/s41388-024-03036-x","article-title":"Alternative splicing in prostate cancer progression and therapeutic resistance","volume":"43","author":"Rawat","year":"2024","journal-title":"Oncogene"},{"issue":"11","key":"10.1016\/j.bbcan.2025.189506_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.110109","article-title":"Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer","volume":"37","author":"Long","year":"2021","journal-title":"Cell Rep."},{"issue":"10","key":"10.1016\/j.bbcan.2025.189506_bb0035","doi-asserted-by":"crossref","first-page":"907","DOI":"10.2217\/fon-2017-0531","article-title":"Sipuleucel-T for the treatment of prostate cancer: novel insights and future directions","volume":"14","author":"Handy","year":"2018","journal-title":"Future Oncol."},{"issue":"13","key":"10.1016\/j.bbcan.2025.189506_bb0040","doi-asserted-by":"crossref","first-page":"3753","DOI":"10.1158\/1078-0432.CCR-18-4070","article-title":"FDA approval summary: Pembrolizumab for the treatment of microsatellite instability-high solid tumors","volume":"25","author":"Marcus","year":"2019","journal-title":"Clin. Cancer Res."},{"issue":"3","key":"10.1016\/j.bbcan.2025.189506_bb0045","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1038\/s41391-021-00340-5","article-title":"How to turn up the heat on the cold immune microenvironment of metastatic prostate cancer","volume":"24","author":"Stultz","year":"2021","journal-title":"Prostate Cancer Prostatic Dis."},{"issue":"3","key":"10.1016\/j.bbcan.2025.189506_bb0050","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1097\/CCO.0000000000000719","article-title":"Understanding the tumor-immune microenvironment in prostate cancer","volume":"33","author":"Dong","year":"2021","journal-title":"Curr. Opin. Oncol."},{"issue":"1","key":"10.1016\/j.bbcan.2025.189506_bb0055","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.canlet.2015.12.022","article-title":"Regulation of prostate cancer progression by the tumor microenvironment","volume":"380","author":"Shiao","year":"2016","journal-title":"Cancer Lett."},{"issue":"36","key":"10.1016\/j.bbcan.2025.189506_bb0060","doi-asserted-by":"crossref","first-page":"4828","DOI":"10.1200\/JCO.2011.38.0899","article-title":"Cancer immunotherapy comes of age","volume":"29","author":"Topalian","year":"2011","journal-title":"J. Clin. Oncol."},{"issue":"7","key":"10.1016\/j.bbcan.2025.189506_bb0065","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1007\/s00702-010-0562-9","article-title":"Transcriptional regulation and multiple functions of MAO genes","volume":"118","author":"Shih","year":"2011","journal-title":"J. Neural Transm. (Vienna)"},{"key":"10.1016\/j.bbcan.2025.189506_bb0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2023.216188","article-title":"Monoamine oxidase a (MAOA): a promising target for prostate cancer therapy","volume":"563","author":"Han","year":"2023","journal-title":"Cancer Lett."},{"issue":"16","key":"10.1016\/j.bbcan.2025.189506_bb0075","doi-asserted-by":"crossref","first-page":"3305","DOI":"10.1038\/s41388-020-1217-4","article-title":"MAOA-mediated reprogramming of stromal fibroblasts promotes prostate tumorigenesis and cancer stemness","volume":"39","author":"Li","year":"2020","journal-title":"Oncogene"},{"key":"10.1016\/j.bbcan.2025.189506_bb0080","article-title":"Stromal-derived MAOB promotes prostate cancer growth and progression","volume":"10(6):eadi4935","author":"Pu","year":"2024","journal-title":"Sci. Adv."},{"issue":"3","key":"10.1016\/j.bbcan.2025.189506_bb0085","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1007\/s00262-023-03622-0","article-title":"Targeting monoamine oxidase a: a strategy for inhibiting tumor growth with both immune checkpoint inhibitors and immune modulators","volume":"73","author":"Ma","year":"2024","journal-title":"Cancer Immunol. Immunother."},{"issue":"7","key":"10.1016\/j.bbcan.2025.189506_bb0090","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1111\/j.1432-0436.2007.00263.x","article-title":"Inhibition of monoamine oxidase a promotes secretory differentiation in basal prostatic epithelial cells","volume":"76","author":"Zhao","year":"2008","journal-title":"Differentiation"},{"issue":"8","key":"10.1016\/j.bbcan.2025.189506_bb0095","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1002\/stem.2831","article-title":"Monoamine oxidase deficiency causes prostate atrophy and reduces prostate progenitor cell activity","volume":"36","author":"Yin","year":"2018","journal-title":"Stem Cells"},{"key":"10.1016\/j.bbcan.2025.189506_bb0100","article-title":"Monoamine oxidase a: An emerging therapeutic target in prostate cancer","volume":"13","author":"Chen","year":"2023","journal-title":"Front. Oncol."},{"issue":"8","key":"10.1016\/j.bbcan.2025.189506_bb0105","doi-asserted-by":"crossref","first-page":"3913","DOI":"10.1210\/en.2004-0311","article-title":"Identification and validation of novel androgen-regulated genes in prostate cancer","volume":"145","author":"Velasco","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.bbcan.2025.189506_bb0110","article-title":"LNCaP Atlas: gene expression associated with in vivo progression to castration-recurrent prostate cancer","author":"Romanuik","year":"2025","journal-title":"BMC Med. Genet."},{"issue":"16","key":"10.1016\/j.bbcan.2025.189506_bb0115","doi-asserted-by":"crossref","first-page":"4275","DOI":"10.1158\/0008-5472.CAN-21-0198","article-title":"Bidirectional cross-talk between MAOA and AR promotes hormone-dependent and castration-resistant prostate cancer","volume":"81","author":"Wei","year":"2021","journal-title":"Cancer Res."},{"issue":"3","key":"10.1016\/j.bbcan.2025.189506_bb0120","doi-asserted-by":"crossref","first-page":"656","DOI":"10.20517\/cdr.2023.48","article-title":"A review of strategies to overcome immune resistance in the treatment of advanced prostate cancer","volume":"6","author":"Sooi","year":"2023","journal-title":"Cancer Drug Resist."},{"issue":"9","key":"10.1016\/j.bbcan.2025.189506_bb0125","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0104271","article-title":"Chemotherapy-induced monoamine oxidase expression in prostate carcinoma functions as a cytoprotective resistance enzyme and associates with clinical outcomes","volume":"9","author":"Gordon","year":"2014","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.bbcan.2025.189506_bb0130","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1002\/pros.23774","article-title":"Effect of monoamine oxidase a (MAOA) inhibitors on androgen-sensitive and castration-resistant prostate cancer cells","volume":"79","author":"Gaur","year":"2019","journal-title":"Prostate"},{"issue":"6","key":"10.1016\/j.bbcan.2025.189506_bb0135","doi-asserted-by":"crossref","first-page":"3225","DOI":"10.1007\/s11010-024-05192-w","article-title":"The highs and lows of monoamine oxidase as molecular target in cancer: an updated review","volume":"480","author":"H\u00e2ncu","year":"2025","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.bbcan.2025.189506_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.curtheres.2020.100610","article-title":"Association of Monoamine Oxidase a with tumor burden and castration resistance in prostate Cancer","volume":"93","author":"Meenu","year":"2020","journal-title":"Curr. Ther. Res. Clin. Exp."},{"issue":"3","key":"10.1016\/j.bbcan.2025.189506_bb0145","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.ccell.2017.02.003","article-title":"MAOA-dependent activation of Shh-IL6-RANKL signaling network promotes prostate Cancer metastasis by engaging tumor-stromal cell interactions","volume":"31","author":"Wu","year":"2017","journal-title":"Cancer Cell"},{"issue":"4","key":"10.1016\/j.bbcan.2025.189506_bb0150","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.7150\/thno.104135","article-title":"JARID1D-dependent androgen receptor and JunD signaling activation of osteoclast differentiation inhibits prostate cancer bone metastasis through demethylating H3K4","volume":"15","author":"Hu","year":"2025","journal-title":"Theranostics"},{"key":"10.1016\/j.bbcan.2025.189506_bb0155","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.bbrc.2022.10.016","article-title":"Deletion of monoamine oxidase a in a prostate cancer model enhances anti-tumor immunity through reduced immune suppression","volume":"634","author":"Lapierre","year":"2022","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"3","key":"10.1016\/j.bbcan.2025.189506_bb0160","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2024-010555","article-title":"Inhibition of stromal MAOA leading activation of WNT5A enhance prostate cancer immunotherapy by involving the transition of cancer-associated fibroblasts","volume":"13","author":"Zhao","year":"2025","journal-title":"J. Immunother. Cancer"},{"issue":"38","key":"10.1016\/j.bbcan.2025.189506_bb0165","doi-asserted-by":"crossref","first-page":"5175","DOI":"10.1038\/s41388-018-0325-x","article-title":"Loss of MAOA in epithelia inhibits adenocarcinoma development, cell proliferation and cancer stem cells in prostate","volume":"37","author":"Liao","year":"2018","journal-title":"Oncogene"},{"issue":"1","key":"10.1016\/j.bbcan.2025.189506_bb0170","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/s12894-023-01285-8","article-title":"High monoamine oxidase a expression predicts poor prognosis for prostate cancer patients","volume":"23","author":"Chen","year":"2023","journal-title":"BMC Urol."},{"issue":"7","key":"10.1016\/j.bbcan.2025.189506_bb0175","doi-asserted-by":"crossref","first-page":"2891","DOI":"10.1172\/JCI70982","article-title":"Monoamine oxidase a mediates prostate tumorigenesis and cancer metastasis","volume":"124","author":"Wu","year":"2014","journal-title":"J. Clin. Invest."},{"issue":"8","key":"10.1016\/j.bbcan.2025.189506_bb0180","doi-asserted-by":"crossref","DOI":"10.1111\/jcmm.18229","article-title":"MAOB expression correlates with a favourable prognosis in prostate cancer, and its genetic variants are associated with the metastasis of the disease","volume":"28","author":"Huang","year":"2024","journal-title":"J. Cell. Mol. Med."},{"issue":"9","key":"10.1016\/j.bbcan.2025.189506_bb0185","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.3390\/cells11091583","article-title":"An ex vivo 3D tumor microenvironment-mimicry culture to study TAM modulation of cancer immunotherapy","volume":"11","author":"Li","year":"2022","journal-title":"Cells"},{"issue":"1","key":"10.1016\/j.bbcan.2025.189506_bb0190","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s10020-019-0126-x","article-title":"Role of 5-HT7 receptors in the immune system in health and disease","volume":"26","author":"Quintero-Villegas","year":"2019","journal-title":"Mol. Med."},{"key":"10.1016\/j.bbcan.2025.189506_bb0195","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.864739","article-title":"Dual relationship between stromal cells and immune cells in the tumor microenvironment","volume":"13","author":"Mun","year":"2022","journal-title":"Front. Immunol."},{"issue":"17","key":"10.1016\/j.bbcan.2025.189506_bb0200","doi-asserted-by":"crossref","first-page":"3026","DOI":"10.2174\/0929867324666170830111531","article-title":"Targeting CXCL12\/CXCR4 Axis in tumor immunotherapy","volume":"26","author":"Zhou","year":"2019","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.bbcan.2025.189506_bb0205","article-title":"Targeting monoamine oxidase a for T cell-based cancer immunotherapy","volume":"6(59):eabh2383","author":"Wang","year":"2021","journal-title":"Sci. Immunol."},{"issue":"1","key":"10.1016\/j.bbcan.2025.189506_bb0210","doi-asserted-by":"crossref","first-page":"3530","DOI":"10.1038\/s41467-021-23164-2","article-title":"Targeting monoamine oxidase A-regulated tumor-associated macrophage polarization for cancer immunotherapy","volume":"12","author":"Wang","year":"2021","journal-title":"Nat. Commun."},{"issue":"36","key":"10.1016\/j.bbcan.2025.189506_bb0215","doi-asserted-by":"crossref","first-page":"14040","DOI":"10.1074\/jbc.RA118.002321","article-title":"Regulation of monoamine oxidase a (MAO-A) expression, activity, and function in IL-13-stimulated monocytes and A549 lung carcinoma cells","volume":"293","author":"Dhabal","year":"2018","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbcan.2025.189506_bb0220","doi-asserted-by":"crossref","first-page":"48","DOI":"10.3389\/fcvm.2017.00048","article-title":"The effects of serotonin in immune cells","volume":"4","author":"Herr","year":"2017","journal-title":"Front. Cardiovasc. Med."},{"issue":"9","key":"10.1016\/j.bbcan.2025.189506_bb0225","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1359\/JBMR.040606","article-title":"Serotonin regulates osteoclast differentiation through its transporter","volume":"19","author":"Battaglino","year":"2004","journal-title":"J. Bone Miner. Res."},{"issue":"Suppl","key":"10.1016\/j.bbcan.2025.189506_bb0230","doi-asserted-by":"crossref","first-page":"245","DOI":"10.2152\/jmi.52.245","article-title":"Approach to novel functional foods for stress control 4. Regulation of serotonin transporter by food factors","volume":"52","author":"Ito","year":"2005","journal-title":"J. Med. Investig."},{"issue":"4","key":"10.1016\/j.bbcan.2025.189506_bb0235","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.cmet.2020.03.003","article-title":"Microbiota-derived metabolites suppress arthritis by amplifying aryl-hydrocarbon receptor activation in regulatory B cells","volume":"31","author":"Rosser","year":"2020","journal-title":"Cell Metab."},{"issue":"6","key":"10.1016\/j.bbcan.2025.189506_bb0240","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1038\/s41590-018-0107-1","article-title":"Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans","volume":"19","author":"Shinde","year":"2018","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.bbcan.2025.189506_bb0245","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.3389\/fimmu.2018.02033","article-title":"Aryl hydrocarbon receptor promotes IL-10 expression in inflammatory macrophages through Src-STAT3 signaling pathway","volume":"9","author":"Zhu","year":"2018","journal-title":"Front. Immunol."},{"issue":"10","key":"10.1016\/j.bbcan.2025.189506_bb0250","article-title":"Serotonin availability shapes the effects of Phenelzine on inflammatory response and gene expression in macrophages","volume":"16","author":"Mahdianipur","year":"2024","journal-title":"Cureus"},{"issue":"1","key":"10.1016\/j.bbcan.2025.189506_bb0255","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.coph.2011.02.004","article-title":"5-HT and the immune system","volume":"11","author":"Ahern","year":"2011","journal-title":"Curr. Opin. Pharmacol."},{"issue":"11","key":"10.1016\/j.bbcan.2025.189506_bb0260","doi-asserted-by":"crossref","first-page":"5296","DOI":"10.7150\/thno.55986","article-title":"Role of serotonin receptor signaling in cancer cells and anti-tumor immunity","volume":"11","author":"Karmakar","year":"2021","journal-title":"Theranostics"},{"issue":"1","key":"10.1016\/j.bbcan.2025.189506_bb0265","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1038\/s41391-020-0211-9","article-title":"Phase 2 trial of monoamine oxidase inhibitor phenelzine in biochemical recurrent prostate cancer","volume":"24","author":"Gross","year":"2021","journal-title":"Prostate Cancer Prostatic Dis."},{"key":"10.1016\/j.bbcan.2025.189506_bb0270","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.bbrc.2022.03.096","article-title":"Monoamine oxidase A drives neuroendocrine differentiation in prostate cancer","volume":"606","author":"Shui","year":"2022","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"6","key":"10.1016\/j.bbcan.2025.189506_bb0275","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s11307-005-0016-1","article-title":"Translational neuroimaging: positron emission tomography studies of monoamine oxidase","volume":"7","author":"Fowler","year":"2005","journal-title":"Mol. Imaging Biol."},{"issue":"11","key":"10.1016\/j.bbcan.2025.189506_bb0280","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1021\/acsptsci.3c00175","article-title":"Molecular imaging of monoamine oxidase a expression in highly aggressive prostate Cancer: synthesis and preclinical evaluation of positron emission tomography tracers","volume":"6","author":"Zirbesegger","year":"2023","journal-title":"ACS Pharmacol. Transl. Sci."},{"issue":"17","key":"10.1016\/j.bbcan.2025.189506_bb0285","doi-asserted-by":"crossref","first-page":"3087","DOI":"10.1038\/s41388-021-01754-0","article-title":"Targeting the glucocorticoid receptor signature gene mono amine oxidase-a enhances the efficacy of chemo- and anti-androgen therapy in advanced prostate cancer","volume":"40","author":"Puhr","year":"2021","journal-title":"Oncogene"},{"issue":"2","key":"10.1016\/j.bbcan.2025.189506_bb0290","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0001616","article-title":"MAO-B elevation in mouse brain astrocytes results in Parkinson\u2019s pathology","volume":"3","author":"Mallajosyula","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.bbcan.2025.189506_bb0295","doi-asserted-by":"crossref","DOI":"10.1038\/srep21986","article-title":"Inhibitory effect of traditional oriental medicine-derived monoamine oxidase B inhibitor on radioresistance of non-small cell lung cancer","volume":"6","author":"Son","year":"2016","journal-title":"Sci. Rep."},{"issue":"22","key":"10.1016\/j.bbcan.2025.189506_bb0305","doi-asserted-by":"crossref","first-page":"3728","DOI":"10.1158\/0008-5472.CAN-24-0932","article-title":"YAP1 inhibition induces phenotype switching of Cancer-associated fibroblasts to tumor suppressive in prostate Cancer","volume":"84","author":"Song","year":"2024","journal-title":"Cancer Res."},{"key":"10.1016\/j.bbcan.2025.189506_bb0310","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/354957","article-title":"Immunomodulatory effects mediated by serotonin","volume":"2015","author":"Arreola","year":"2015","journal-title":"J Immunol Res"},{"issue":"12","key":"10.1016\/j.bbcan.2025.189506_bb0315","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.3390\/genes15121541","article-title":"5-Hydroxytryptamine G-protein-coupled receptor family genes: key players in Cancer prognosis, immune regulation, and therapeutic response","volume":"15","author":"Liu","year":"2024","journal-title":"Genes (Basel)"},{"key":"10.1016\/j.bbcan.2025.189506_bb0320","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/978-3-319-07320-0_9","article-title":"Serotonin modulation of macrophage polarization: inflammation and beyond","volume":"824","author":"de Las","year":"2014","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.bbcan.2025.189506_bb0325","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.970324","article-title":"Nanoformulation improves antitumor efficacy of MAOI immune checkpoint blockade therapy without causing aggression-related side effects","volume":"13","author":"Brown","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"7","key":"10.1016\/j.bbcan.2025.189506_bb0330","doi-asserted-by":"crossref","first-page":"6804","DOI":"10.3390\/ijms24076804","article-title":"Monitoring Nrf2\/ARE pathway activity with a new zebrafish reporter system","volume":"24","author":"Badenetti","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"10.1016\/j.bbcan.2025.189506_bb0335","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1093\/carcin\/bgac045","article-title":"Understanding the role of dopamine in cancer: past, present and future","volume":"43","author":"Grant","year":"2022","journal-title":"Carcinogenesis"},{"issue":"6","key":"10.1016\/j.bbcan.2025.189506_bb0340","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1016\/j.jhep.2014.02.025","article-title":"Monoamine oxidase a suppresses hepatocellular carcinoma metastasis by inhibiting the adrenergic system and its transactivation of EGFR signaling","volume":"60","author":"Li","year":"2014","journal-title":"J. Hepatol."},{"issue":"1","key":"10.1016\/j.bbcan.2025.189506_bb0345","doi-asserted-by":"crossref","first-page":"6115","DOI":"10.1038\/s41598-020-63150-0","article-title":"Monoamine oxidase a is down-regulated in EBV-associated nasopharyngeal carcinoma","volume":"10","author":"Lee","year":"2020","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.bbcan.2025.189506_bb0350","doi-asserted-by":"crossref","first-page":"477","DOI":"10.3233\/JPD-212976","article-title":"Monoamine oxidase-B inhibitors for the treatment of Parkinson\u2019s disease: past, present, and future","volume":"12","author":"Tan","year":"2022","journal-title":"J. Parkinsons Dis."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Reviews on Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304419X25002483?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304419X25002483?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T12:13:37Z","timestamp":1768911217000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304419X25002483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":69,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S0304419X25002483"],"URL":"https:\/\/doi.org\/10.1016\/j.bbcan.2025.189506","relation":{},"ISSN":["0304-419X"],"issn-type":[{"value":"0304-419X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Targeting MAO offers a novel immunotherapeutic strategy for prostate cancer by modulating the \u201ctumor-stroma-immune\u201d interaction network","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Reviews on Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbcan.2025.189506","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"189506"}}