{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T01:08:38Z","timestamp":1789520918580,"version":"build-2803163510"},"reference-count":150,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100017633","name":"Shanghai Anti-Cancer Association","doi-asserted-by":"publisher","award":["SACA-CY21C08"],"award-info":[{"award-number":["SACA-CY21C08"]}],"id":[{"id":"10.13039\/100017633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003395","name":"Shanghai Municipal Education Commission","doi-asserted-by":"publisher","award":["20191425"],"award-info":[{"award-number":["20191425"]}],"id":[{"id":"10.13039\/501100003395","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2021M702182"],"award-info":[{"award-number":["2021M702182"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82472921"],"award-info":[{"award-number":["82472921"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82203751"],"award-info":[{"award-number":["82203751"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Reviews on Cancer"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.bbcan.2026.189671","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T23:20:54Z","timestamp":1785453654000},"page":"189671","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Temporal and spatial molecular heterogeneity of gastric cancer: Roles of post-translational modifications"],"prefix":"10.1016","volume":"1881","author":[{"given":"Tian-Ao","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren-Chao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.bbcan.2026.189671_bb0005","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1136\/gutjnl-2024-332815","article-title":"Stomach microbiota in gastric cancer development and clinical implications","volume":"73","author":"Zeng","year":"2024","journal-title":"Gut"},{"key":"10.1016\/j.bbcan.2026.189671_bb0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.critrevonc.2022.103841","article-title":"Characteristics of gastric cancer around the world","volume":"181","author":"L\u00f3pez","year":"2023","journal-title":"Crit. Rev. Oncol. Hematol."},{"issue":"5","key":"10.1016\/j.bbcan.2026.189671_bb0015","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1158\/1055-9965.EPI-13-1057","article-title":"Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention","volume":"23","author":"Karimi","year":"2014","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"issue":"5","key":"10.1016\/j.bbcan.2026.189671_bb0020","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1001\/jama.2025.20034","article-title":"Gastric cancer: a review","volume":"335","author":"Patel","year":"2026","journal-title":"JAMA"},{"issue":"46","key":"10.1016\/j.bbcan.2026.189671_bb0025","doi-asserted-by":"crossref","first-page":"17618","DOI":"10.3748\/wjg.v20.i46.17618","article-title":"Epidemiology of Helicobacter pylori infection among the healthy population in Iran and countries of the eastern Mediterranean region: a systematic review of prevalence and risk factors","volume":"20","author":"Eshraghian","year":"2014","journal-title":"World J. Gastroenterol."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0030","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1158\/1055-9965.EPI-11-0834","article-title":"Sex hormones, hormonal interventions, and gastric cancer risk: a meta-analysis","volume":"21","author":"Camargo","year":"2012","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"issue":"5","key":"10.1016\/j.bbcan.2026.189671_bb0035","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1093\/annonc\/mdw040","article-title":"Molecular classification of gastric cancer","volume":"27","author":"Chia","year":"2016","journal-title":"Ann. Oncol."},{"issue":"7517","key":"10.1016\/j.bbcan.2026.189671_bb0040","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1038\/nature13480","article-title":"Comprehensive molecular characterization of gastric adenocarcinoma","volume":"513","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.bbcan.2026.189671_bb0045","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2024.1485580","article-title":"Lactylation-related gene signature accurately predicts prognosis and immunotherapy response in gastric cancer","volume":"14","author":"Sun","year":"2024","journal-title":"Front. Oncol."},{"issue":"10","key":"10.1016\/j.bbcan.2026.189671_bb0050","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1038\/s41419-023-06183-3","article-title":"The mechanism of linear ubiquitination in regulating cell death and correlative diseases","volume":"14","author":"Gao","year":"2023","journal-title":"Cell Death Dis."},{"issue":"4","key":"10.1016\/j.bbcan.2026.189671_bb0055","doi-asserted-by":"crossref","DOI":"10.3390\/cancers12040902","article-title":"Drug development targeting the ubiquitin-proteasome system (UPS) for the treatment of human cancers","volume":"12","author":"Zhang","year":"2020","journal-title":"Cancers (Basel)"},{"issue":"5","key":"10.1016\/j.bbcan.2026.189671_bb0060","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.molcel.2013.01.017","article-title":"Regulation of DNA damage responses by ubiquitin and SUMO","volume":"49","author":"Jackson","year":"2013","journal-title":"Mol. Cell"},{"issue":"24","key":"10.1016\/j.bbcan.2026.189671_bb0065","doi-asserted-by":"crossref","first-page":"6953","DOI":"10.1016\/j.cell.2025.09.006","article-title":"Sequencing-free whole-genome spatial transcriptomics at single-molecule resolution","volume":"188","author":"Cheng","year":"2025","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0070","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.294","article-title":"Spatiotemporal molecular medicine: a new era of clinical and translational medicine","volume":"11","author":"Wang","year":"2021","journal-title":"Clin. Transl. Med."},{"issue":"10","key":"10.1016\/j.bbcan.2026.189671_bb0075","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1038\/s41580-023-00615-w","article-title":"The technological landscape and applications of single-cell multi-omics","volume":"24","author":"Baysoy","year":"2023","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0080","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/s41392-022-00960-w","article-title":"Clinical and translational values of spatial transcriptomics","volume":"7","author":"Zhang","year":"2022","journal-title":"Signal Transduct. Target. Ther."},{"issue":"6294","key":"10.1016\/j.bbcan.2026.189671_bb0085","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1126\/science.aaf2403","article-title":"Visualization and analysis of gene expression in tissue sections by spatial transcriptomics","volume":"353","author":"St\u00e5hl","year":"2016","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.bbcan.2026.189671_bb0090","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1038\/s41551-020-0578-x","article-title":"Integrating spatial gene expression and breast tumour morphology via deep learning","volume":"4","author":"He","year":"2020","journal-title":"Nat. Biomed. Eng."},{"issue":"4","key":"10.1016\/j.bbcan.2026.189671_bb0095","doi-asserted-by":"crossref","first-page":"152","DOI":"10.3892\/ol.2024.14285","article-title":"Applications of single-cell omics and spatial transcriptomics technologies in gastric cancer (review)","volume":"27","author":"Ren","year":"2024","journal-title":"Oncol. Lett."},{"issue":"2","key":"10.1016\/j.bbcan.2026.189671_bb0100","first-page":"84","article-title":"Spatiotemporal omics-refining the landscape of precision medicine","volume":"1","author":"Zhang","year":"2022","journal-title":"Lifestyle Med."},{"issue":"3","key":"10.1016\/j.bbcan.2026.189671_bb0105","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1158\/2159-8290.CD-21-0683","article-title":"Single-cell atlas of lineage states, tumor microenvironment, and subtype-specific expression programs in gastric cancer","volume":"12","author":"Kumar","year":"2022","journal-title":"Cancer Discov."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0110","doi-asserted-by":"crossref","first-page":"192","DOI":"10.5230\/jgc.2025.25.e3","article-title":"Spatial and temporal tumor heterogeneity in gastric cancer: discordance of predictive biomarkers","volume":"25","author":"Lee","year":"2025","journal-title":"J. Gastric Cancer."},{"issue":"2","key":"10.1016\/j.bbcan.2026.189671_bb0115","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.trecan.2023.11.001","article-title":"Targeting HER2 heterogeneity in breast and gastrointestinal cancers","volume":"10","author":"Valenza","year":"2024","journal-title":"Trends Cancer"},{"issue":"6","key":"10.1016\/j.bbcan.2026.189671_bb0120","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1080\/19490976.2020.1774311","article-title":"Inhibition of autophagy aggravates DNA damage response and gastric tumorigenesis via Rad51 ubiquitination in response to H. pylori infection","volume":"11","author":"Xie","year":"2020","journal-title":"Gut Microbes"},{"issue":"5","key":"10.1016\/j.bbcan.2026.189671_bb0125","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1038\/s41388-020-01572-w","article-title":"A novel UBE2T inhibitor suppresses Wnt\/\u03b2-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination","volume":"40","author":"Yu","year":"2021","journal-title":"Oncogene"},{"key":"10.1016\/j.bbcan.2026.189671_bb0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2024.103479","article-title":"NSUN2 lactylation drives cancer cell resistance to ferroptosis through enhancing GCLC-dependent glutathione synthesis","volume":"79","author":"Niu","year":"2025","journal-title":"Redox Biol."},{"issue":"27","key":"10.1016\/j.bbcan.2026.189671_bb0135","article-title":"Succinylation inhibits the enzymatic hydrolysis of the extracellular matrix protein fibrillin 1 and promotes gastric cancer progression","volume":"9","author":"Wang","year":"2022","journal-title":"Adv. Sci. (Weinh)"},{"issue":"4","key":"10.1016\/j.bbcan.2026.189671_bb0140","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1038\/s41419-024-06666-x","article-title":"ACAT2 suppresses the ubiquitination of YAP1 to enhance the proliferation and metastasis ability of gastric cancer via the upregulation of SETD7","volume":"15","author":"Zhang","year":"2024","journal-title":"Cell Death Dis."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0145","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1186\/s13046-020-01681-0","article-title":"Lysine-222 succinylation reduces lysosomal degradation of lactate dehydrogenase a and is increased in gastric cancer","volume":"39","author":"Li","year":"2020","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"10.1016\/j.bbcan.2026.189671_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2024.116120","article-title":"H3K18 lactylation-mediated VCAM1 expression promotes gastric cancer progression and metastasis via AKT-mTOR-CXCL1 axis","volume":"222","author":"Zhao","year":"2024","journal-title":"Biochem. Pharmacol."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0155","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1038\/s41392-023-01450-3","article-title":"TRIM28 promotes the escape of gastric cancer cells from immune surveillance by increasing PD-L1 abundance","volume":"8","author":"Ma","year":"2023","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.bbcan.2026.189671_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2023.216510","article-title":"TRIM29 promotes antitumor immunity through enhancing IGF2BP1 ubiquitination and subsequent PD-L1 downregulation in gastric cancer","volume":"581","author":"Jiang","year":"2024","journal-title":"Cancer Lett."},{"issue":"8","key":"10.1016\/j.bbcan.2026.189671_bb0165","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1007\/s00432-024-05927-8","article-title":"NUSAP1 promotes gastric cancer radioresistance by inhibiting ubiquitination of ANXA2 and is suppressed by miR-129-5p","volume":"150","author":"Ge","year":"2024","journal-title":"J. Cancer Res. Clin. Oncol."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0170","first-page":"23","article-title":"Helicobacter pylori","volume":"114","author":"Egli","year":"2025","journal-title":"Praxis (Bern 1994)"},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0175","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s13045-024-01654-2","article-title":"Helicobacter pylori and gastric cancer: mechanisms and new perspectives","volume":"18","author":"Duan","year":"2025","journal-title":"J. Hematol. Oncol."},{"issue":"16","key":"10.1016\/j.bbcan.2026.189671_bb0180","doi-asserted-by":"crossref","first-page":"2452","DOI":"10.3748\/wjg.v29.i16.2452","article-title":"Updates on global epidemiology, risk and prognostic factors of gastric cancer","volume":"29","author":"Yang","year":"2023","journal-title":"World J. Gastroenterol."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0185","doi-asserted-by":"crossref","DOI":"10.1111\/hel.12544","article-title":"Helicobacter pylori VacA, a distinct toxin exerts diverse functionalities in numerous cells: an overview","volume":"24","author":"Chauhan","year":"2019","journal-title":"Helicobacter"},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0190","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2024.2314201","article-title":"The Helicobacter pylori cag pathogenicity island as a determinant of gastric cancer risk","volume":"16","author":"Tran","year":"2024","journal-title":"Gut Microbes"},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0195","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/19490976.2021.1909459","article-title":"The interplay between Helicobacter pylori and gastrointestinal microbiota","volume":"13","author":"Chen","year":"2021","journal-title":"Gut Microbes"},{"issue":"2","key":"10.1016\/j.bbcan.2026.189671_bb0200","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/s15010-023-02115-7","article-title":"Helicobacter pylori and oral-gut microbiome: clinical implications","volume":"52","author":"Elghannam","year":"2024","journal-title":"Infection"},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0205","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1186\/s13046-018-0962-5","article-title":"Helicobacter pylori CagA promotes epithelial mesenchymal transition in gastric carcinogenesis via triggering oncogenic YAP pathway","volume":"37","author":"Li","year":"2018","journal-title":"J. Exp. Clin. Cancer Res."},{"issue":"11","key":"10.1016\/j.bbcan.2026.189671_bb0210","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.1481","article-title":"H. pylori-induced NF-\u03baB-PIEZO1-YAP1-CTGF axis drives gastric cancer progression and cancer-associated fibroblast-mediated tumour microenvironment remodelling","volume":"13","author":"Chen","year":"2023","journal-title":"Clin. Transl. Med."},{"issue":"3","key":"10.1016\/j.bbcan.2026.189671_bb0215","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.jcmgh.2017.02.002","article-title":"Oxidative stress resulting from Helicobacter pylori infection contributes to gastric carcinogenesis","volume":"3","author":"Butcher","year":"2017","journal-title":"Cell. Mol. Gastroenterol. Hepatol."},{"issue":"6","key":"10.1016\/j.bbcan.2026.189671_bb0220","doi-asserted-by":"crossref","first-page":"735","DOI":"10.5009\/gnl19312","article-title":"Helicobacter pylori eradication induced constant decrease in interleukin- 1B expression over more than 5 years in patients with gastric cancer and dysplasia","volume":"14","author":"Kim","year":"2020","journal-title":"Gut Liver"},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0225","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s13046-022-02586-w","article-title":"Helicobacter pylori-induced NAT10 stabilizes MDM2 mRNA via RNA acetylation to facilitate gastric cancer progression","volume":"42","author":"Deng","year":"2023","journal-title":"J. Exp. Clin. Cancer Res."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0230","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s13062-023-00402-9","article-title":"CircRNA_15430 reduced by Helicobacter pylori infection and suppressed gastric cancer progression via miR-382-5p\/ZCCHC14 axis","volume":"18","author":"Liu","year":"2023","journal-title":"Biol. Direct"},{"issue":"111","key":"10.1016\/j.bbcan.2026.189671_bb0235","first-page":"285","article-title":"Role of Helicobacter pylori in gastric cancer: advances and controversies","volume":"20","author":"Meng","year":"2015","journal-title":"Discov. Med."},{"issue":"12","key":"10.1016\/j.bbcan.2026.189671_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2023.108414","article-title":"Helicobacter pylori CagA promotes immune evasion of gastric cancer by upregulating PD-L1 level in exosomes","volume":"26","author":"Wang","year":"2023","journal-title":"iScience"},{"issue":"2","key":"10.1016\/j.bbcan.2026.189671_bb0245","article-title":"Helicobacter pylori and immunotherapy for gastrointestinal cancer","volume":"5","author":"Jia","year":"2024","journal-title":"Innovation (Camb)"},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0250","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1186\/s12866-022-02594-y","article-title":"Analysis of gastric microbiome reveals three distinctive microbial communities associated with the occurrence of gastric cancer","volume":"22","author":"Liu","year":"2022","journal-title":"BMC Microbiol."},{"issue":"4","key":"10.1016\/j.bbcan.2026.189671_bb0255","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.cell.2024.01.004","article-title":"Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice","volume":"187","author":"Fu","year":"2024","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0260","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s44342-024-00001-8","article-title":"Gut metagenomic analysis of gastric cancer patients reveals Akkermansia, Gammaproteobacteria, and Veillonella microbiota as potential non-invasive biomarkers","volume":"22","author":"Nath","year":"2024","journal-title":"Genomics Inform."},{"issue":"9","key":"10.1016\/j.bbcan.2026.189671_bb0265","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1038\/s41419-021-04127-3","article-title":"NSUN2 modified by SUMO-2\/3 promotes gastric cancer progression and regulates mRNA m5C methylation","volume":"12","author":"Hu","year":"2021","journal-title":"Cell Death Dis."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0270","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1002\/cac2.12386","article-title":"Cytosolic TGM2 promotes malignant progression in gastric cancer by suppressing the TRIM21-mediated ubiquitination\/degradation of STAT1 in a GTP binding-dependent modality","volume":"43","author":"Zhang","year":"2023","journal-title":"Cancer Commun. (Lond.)"},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0275","doi-asserted-by":"crossref","first-page":"6523","DOI":"10.1038\/s41467-023-42025-8","article-title":"Lactylation of METTL16 promotes cuproptosis via m(6)A-modification on FDX1 mRNA in gastric cancer","volume":"14","author":"Sun","year":"2023","journal-title":"Nat. Commun."},{"issue":"18","key":"10.1016\/j.bbcan.2026.189671_bb0280","article-title":"Blocking ubiquitin-specific protease 7 induces ferroptosis in gastric Cancer via targeting stearoyl-CoA desaturase","volume":"11","author":"Guan","year":"2024","journal-title":"Adv. Sci. (Weinh)"},{"issue":"14","key":"10.1016\/j.bbcan.2026.189671_bb0285","doi-asserted-by":"crossref","DOI":"10.3390\/ijms241411386","article-title":"Epithelial-mesenchymal transition (EMT)","volume":"24","author":"Manfioletti","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"8","key":"10.1016\/j.bbcan.2026.189671_bb0290","doi-asserted-by":"crossref","first-page":"e358","DOI":"10.1016\/S1470-2045(21)00343-0","article-title":"Novel therapeutic strategies: targeting epithelial-mesenchymal transition in colorectal cancer","volume":"22","author":"Zhang","year":"2021","journal-title":"Lancet Oncol."},{"issue":"3","key":"10.1016\/j.bbcan.2026.189671_bb0295","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1038\/nrm3758","article-title":"Molecular mechanisms of epithelial-mesenchymal transition","volume":"15","author":"Lamouille","year":"2014","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"6","key":"10.1016\/j.bbcan.2026.189671_bb0300","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbcan.2023.189003","article-title":"Snail transcription factors as key regulators of chemoresistance, stemness and metastasis of ovarian cancer cells","volume":"1878","author":"Kielbik","year":"2023","journal-title":"Biochim. Biophys. Acta Rev. Cancer"},{"issue":"11","key":"10.1016\/j.bbcan.2026.189671_bb0305","doi-asserted-by":"crossref","DOI":"10.15252\/embr.202356902","article-title":"Molecular mechanisms of TWIST1-regulated transcription in EMT and cancer metastasis","volume":"24","author":"Yu","year":"2023","journal-title":"EMBO Rep."},{"issue":"12","key":"10.1016\/j.bbcan.2026.189671_bb0310","doi-asserted-by":"crossref","first-page":"4521","DOI":"10.1111\/cas.15987","volume":"114","author":"Sumitomo","year":"2023","journal-title":"Cancer Sci."},{"issue":"44","key":"10.1016\/j.bbcan.2026.189671_bb0315","doi-asserted-by":"crossref","first-page":"6802","DOI":"10.1038\/s41388-020-01471-0","article-title":"Deubiquitinase USP29 promotes gastric cancer cell migration by cooperating with phosphatase SCP1 to stabilize Snail protein","volume":"39","author":"Qian","year":"2020","journal-title":"Oncogene"},{"key":"10.1016\/j.bbcan.2026.189671_bb0320","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellsig.2024.111462","article-title":"CAF-secreted LOX promotes PD-L1 expression via histone Lactylation and regulates tumor EMT through TGF\u03b2\/IGF1 signaling in gastric Cancer","volume":"124","author":"Li","year":"2024","journal-title":"Cell. Signal."},{"issue":"14","key":"10.1016\/j.bbcan.2026.189671_bb0325","doi-asserted-by":"crossref","first-page":"4411","DOI":"10.7150\/ijbs.81972","article-title":"RHOJ induces epithelial-to-mesenchymal transition by IL-6\/STAT3 to promote invasion and metastasis in gastric Cancer","volume":"19","author":"Ma","year":"2023","journal-title":"Int. J. Biol. Sci."},{"issue":"4","key":"10.1016\/j.bbcan.2026.189671_bb0330","doi-asserted-by":"crossref","first-page":"3574","DOI":"10.18632\/aging.102831","article-title":"SERPINH1 regulates EMT and gastric cancer metastasis via the Wnt\/\u03b2-catenin signaling pathway","volume":"12","author":"Tian","year":"2020","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.bbcan.2026.189671_bb0335","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/bs.apha.2017.08.002","article-title":"Matrix metalloproteinases, vascular remodeling, and vascular disease","volume":"81","author":"Wang","year":"2018","journal-title":"Adv. Pharmacol."},{"issue":"6","key":"10.1016\/j.bbcan.2026.189671_bb0340","doi-asserted-by":"crossref","DOI":"10.1016\/j.acthis.2023.152071","article-title":"PRSS2 regulates EMT and metastasis via MMP-9 in gastric cancer","volume":"125","author":"Wang","year":"2023","journal-title":"Acta Histochem."},{"issue":"9","key":"10.1016\/j.bbcan.2026.189671_bb0345","doi-asserted-by":"crossref","first-page":"15395","DOI":"10.1002\/jcp.28186","article-title":"SIRT1 inhibits gastric cancer proliferation and metastasis via STAT3\/MMP-13 signaling","volume":"234","author":"Zhang","year":"2019","journal-title":"J. Cell. Physiol."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0350","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/s12943-020-01208-3","article-title":"Exosomal circSHKBP1 promotes gastric cancer progression via regulating the miR-582-3p\/HUR\/VEGF axis and suppressing HSP90 degradation","volume":"19","author":"Xie","year":"2020","journal-title":"Mol. Cancer"},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0355","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1186\/s13046-022-02499-8","article-title":"Gastric cancer-derived exosomal miR-519a-3p promotes liver metastasis by inducing intrahepatic M2-like macrophage-mediated angiogenesis","volume":"41","author":"Qiu","year":"2022","journal-title":"J. Exp. Clin. Cancer Res."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0360","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.jhep.2023.10.006","article-title":"Endothelial DGKG promotes tumor angiogenesis and immune evasion in hepatocellular carcinoma","volume":"80","author":"Zhang","year":"2024","journal-title":"J. Hepatol."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0365","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.ccell.2020.12.001","article-title":"Integrin \u03b1v\u03b26-TGF\u03b2-SOX4 pathway drives immune evasion in triple-negative breast cancer","volume":"39","author":"Bagati","year":"2021","journal-title":"Cancer Cell"},{"key":"10.1016\/j.bbcan.2026.189671_bb0370","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.reth.2021.02.006","article-title":"Immune evasion by cancer stem cells","volume":"17","author":"Tsuchiya","year":"2021","journal-title":"Regen Ther."},{"issue":"7","key":"10.1016\/j.bbcan.2026.189671_bb0375","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1016\/j.ccell.2025.05.015","article-title":"Senescence in cancer","volume":"43","author":"Colucci","year":"2025","journal-title":"Cancer Cell"},{"key":"10.1016\/j.bbcan.2026.189671_bb0380","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.3389\/fimmu.2020.01280","article-title":"Cancer stem cells-origins and biomarkers: perspectives for targeted personalized therapies","volume":"11","author":"Walcher","year":"2020","journal-title":"Front. Immunol."},{"issue":"5","key":"10.1016\/j.bbcan.2026.189671_bb0385","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1089\/omi.2021.0025","article-title":"Cancer stem cell marker CD44 plays multiple key roles in human cancers: immune suppression\/evasion, drug resistance, epithelial-mesenchymal transition, and metastasis","volume":"25","author":"Dzobo","year":"2021","journal-title":"Omics"},{"key":"10.1016\/j.bbcan.2026.189671_bb0390","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/9989790","article-title":"Gastric cancer mesenchymal stem cells inhibit NK cell function through mTOR signalling to promote tumour growth","volume":"2021","author":"Guo","year":"2021","journal-title":"Stem Cells Int."},{"key":"10.1016\/j.bbcan.2026.189671_bb0395","doi-asserted-by":"crossref","first-page":"179","DOI":"10.3389\/fimmu.2016.00179","article-title":"A new biological feature of natural killer cells: the recognition of solid tumor-derived cancer stem cells","volume":"7","author":"Tallerico","year":"2016","journal-title":"Front. Immunol."},{"issue":"2","key":"10.1016\/j.bbcan.2026.189671_bb0400","doi-asserted-by":"crossref","first-page":"581","DOI":"10.21037\/jgo-22-167","article-title":"Clinical significance and correlation of miR-200c and P-gp expression in gastric cancer and the effects on multidrug resistance","volume":"13","author":"Wang","year":"2022","journal-title":"J. Gastrointest Oncol."},{"issue":"4","key":"10.1016\/j.bbcan.2026.189671_bb0405","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1038\/sj.bjc.6604211","article-title":"Impacts of excision repair cross-complementing gene 1 (ERCC1), dihydropyrimidine dehydrogenase, and epidermal growth factor receptor on the outcomes of patients with advanced gastric cancer","volume":"98","author":"Matsubara","year":"2008","journal-title":"Br. J. Cancer"},{"issue":"2","key":"10.1016\/j.bbcan.2026.189671_bb0410","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1080\/03602532.2019.1632886","article-title":"Drug metabolizing enzymes-associated chemo resistance and strategies to overcome it","volume":"51","author":"Verma","year":"2019","journal-title":"Drug Metab. Rev."},{"key":"10.1016\/j.bbcan.2026.189671_bb0415","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2021.107443","article-title":"PD-1\/PD-L1 enhanced cisplatin resistance in gastric cancer through PI3K\/AKT mediated P-gp expression","volume":"94","author":"Wu","year":"2021","journal-title":"Int. Immunopharmacol."},{"issue":"10","key":"10.1016\/j.bbcan.2026.189671_bb0420","doi-asserted-by":"crossref","first-page":"8472","DOI":"10.1002\/jcb.27073","article-title":"Effect of 5-fluorouracil on excision repair cross-complementing 1 expression and consequent cytotoxicity regulation in human gastric cancer cells","volume":"119","author":"Liu","year":"2018","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.bbcan.2026.189671_bb0425","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1186\/1746-1596-8-198","article-title":"The association between chemosensitivity and Pgp, GST-\u03c0 and Topo II expression in gastric cancer","volume":"8","author":"Geng","year":"2013","journal-title":"Diagn. Pathol."},{"issue":"4","key":"10.1016\/j.bbcan.2026.189671_bb0430","doi-asserted-by":"crossref","DOI":"10.3390\/cancers13040916","article-title":"Isoforms of the p53 family and gastric Cancer: a m\u00e9nage \u00e0 trois for an unfinished affair","volume":"13","author":"Blanchet","year":"2021","journal-title":"Cancers (Basel)"},{"issue":"3","key":"10.1016\/j.bbcan.2026.189671_bb0435","doi-asserted-by":"crossref","first-page":"794","DOI":"10.20517\/cdr.2022.11","article-title":"Insight into the molecular mechanisms of gastric cancer stem cell in drug resistance of gastric cancer","volume":"5","author":"Xiong","year":"2022","journal-title":"Cancer Drug Resist."},{"key":"10.1016\/j.bbcan.2026.189671_bb0440","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2024.1469180","article-title":"\u03b2-Elemene promotes ferroptosis and reverses radioresistance in gastric cancer by inhibiting the OTUB1-GPX4 interaction","volume":"15","author":"He","year":"2024","journal-title":"Front. Pharmacol."},{"issue":"6","key":"10.1016\/j.bbcan.2026.189671_bb0445","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1093\/gastro\/goab050","article-title":"One stomach, two subtypes of carcinoma-the differences between distal and proximal gastric cancer","volume":"9","author":"Zhang","year":"2021","journal-title":"Gastroenterol. Rep. (Oxf.)"},{"issue":"14","key":"10.1016\/j.bbcan.2026.189671_bb0450","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1200\/JCO.2005.05.2308","article-title":"Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world","volume":"24","author":"Kamangar","year":"2006","journal-title":"J. Clin. Oncol."},{"issue":"5","key":"10.1016\/j.bbcan.2026.189671_bb0455","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1038\/nrc.2016.24","article-title":"Oesophageal adenocarcinoma and gastric cancer: should we mind the gap?","volume":"16","author":"Hayakawa","year":"2016","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.bbcan.2026.189671_bb0460","first-page":"227","article-title":"Helicobacter pylori-induced changes in gastric acid secretion and upper gastrointestinal disease","volume":"400","author":"Smolka","year":"2017","journal-title":"Curr. Top. Microbiol. Immunol."},{"issue":"3","key":"10.1016\/j.bbcan.2026.189671_bb0465","first-page":"214","article-title":"Gastroesophageal reflux disease (GERD)","volume":"115","author":"Clarrett","year":"2018","journal-title":"Mo. Med."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0470","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s10120-014-0425-4","article-title":"Obesity and related risk factors in gastric cardia adenocarcinoma","volume":"18","author":"Olefson","year":"2015","journal-title":"Gastric Cancer"},{"issue":"10","key":"10.1016\/j.bbcan.2026.189671_bb0475","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1111\/jgh.13329","article-title":"Diabetic biomarkers and the risk of proximal or distal gastric cancer","volume":"31","author":"Kim","year":"2016","journal-title":"J. Gastroenterol. Hepatol."},{"issue":"18","key":"10.1016\/j.bbcan.2026.189671_bb0480","doi-asserted-by":"crossref","first-page":"25620","DOI":"10.18632\/oncotarget.8239","article-title":"Integrated epigenomic analyses of enhancer as well as promoter regions in gastric cancer","volume":"7","author":"Baek","year":"2016","journal-title":"Oncotarget"},{"issue":"19","key":"10.1016\/j.bbcan.2026.189671_bb0485","doi-asserted-by":"crossref","first-page":"19595","DOI":"10.1002\/cam4.6583","article-title":"Subsite-specific metastatic organotropism and risk in gastric cancer: a population-based cohort study of the US SEER database and a Chinese single-institutional registry","volume":"12","author":"Wang","year":"2023","journal-title":"Cancer Med."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0490","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1186\/s12967-022-03650-x","article-title":"Microbiota and metabolites alterations in proximal and distal gastric cancer patients","volume":"20","author":"Yang","year":"2022","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.bbcan.2026.189671_bb0495","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.114601","article-title":"Metabolic codependencies in the tumor microenvironment and gastric cancer: difficulties and opportunities","volume":"162","author":"Zhao","year":"2023","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.bbcan.2026.189671_bb0500","article-title":"Significance of lymph node metastasis in the treatment of gastric cancer and current challenges in determining the extent of metastasis","volume":"11","author":"Kinami","year":"2021","journal-title":"Front. Oncol."},{"key":"10.1016\/j.bbcan.2026.189671_bb0505","doi-asserted-by":"crossref","first-page":"217","DOI":"10.2147\/CEG.S310235","article-title":"Importance of mevalonate pathway lipids on the growth and survival of primary and metastatic gastric carcinoma cells","volume":"14","author":"Ortiz","year":"2021","journal-title":"Clin. Exp. Gastroenterol."},{"key":"10.1016\/j.bbcan.2026.189671_bb0510","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.lfs.2019.03.056","article-title":"Clinical importance of FASN in relation to HIF-1\u03b1 and SREBP-1c in gastric adenocarcinoma","volume":"224","author":"Ezzeddini","year":"2019","journal-title":"Life Sci."},{"issue":"5","key":"10.1016\/j.bbcan.2026.189671_bb0515","first-page":"7855","article-title":"ATP citrate lyase expression is associated with advanced stage and prognosis in gastric adenocarcinoma","volume":"8","author":"Qian","year":"2015","journal-title":"Int. J. Clin. Exp. Med."},{"issue":"3","key":"10.1016\/j.bbcan.2026.189671_bb0520","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.devcel.2019.04.012","article-title":"Metastasis organotropism: redefining the congenial soil","volume":"49","author":"Gao","year":"2019","journal-title":"Dev. Cell"},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0525","doi-asserted-by":"crossref","first-page":"17648","DOI":"10.1038\/s41598-024-68411-w","article-title":"Heterogeneity of claudin 18.2 expression in metastatic gastric cancer","volume":"14","author":"Choi","year":"2024","journal-title":"Sci. Rep."},{"issue":"10","key":"10.1016\/j.bbcan.2026.189671_bb0530","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1136\/gutjnl-2020-320805","article-title":"Spatial profiling of gastric cancer patient-matched primary and locoregional metastases reveals principles of tumour dissemination","volume":"70","author":"Sundar","year":"2021","journal-title":"Gut"},{"issue":"08","key":"10.1016\/j.bbcan.2026.189671_bb0535","first-page":"947","article-title":"Gastric mucin-secreting adenocarcinoma: rethinking the pathological classification of gastric adenocarcinoma","volume":"44","author":"Zhang","year":"2024","journal-title":"Chin. J. Pract. Surg."},{"key":"10.1016\/j.bbcan.2026.189671_bb0540","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/8497305","article-title":"Adenocarcinoma with mixed subtypes in the early and advanced gastric cancer","volume":"2021","author":"Zhao","year":"2021","journal-title":"Can. J. Gastroenterol. Hepatol."},{"key":"10.1016\/j.bbcan.2026.189671_bb0545","series-title":"Clinicopathological Characteristics and 3-Year Survival Rate Analysis of Postoperative Patients with Gastric Mucinous Adenocarcinoma","author":"Xie","year":"2024"},{"issue":"2","key":"10.1016\/j.bbcan.2026.189671_bb0550","first-page":"813","article-title":"Mucinous gastric carcinoma: an update of clinicopathologic features and prognostic value from a retrospective study of clinical series","volume":"11","author":"Yuan","year":"2018","journal-title":"Int. J. Clin. Exp. Pathol."},{"issue":"8","key":"10.1016\/j.bbcan.2026.189671_bb0555","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.4251\/wjgo.v14.i8.1406","article-title":"Poorly cohesive cells gastric carcinoma including signet-ring cell cancer: updated review of definition, classification and therapeutic management","volume":"14","author":"Drubay","year":"2022","journal-title":"World J. Gastrointest. Oncol."},{"issue":"8","key":"10.1016\/j.bbcan.2026.189671_bb0560","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1016\/j.cmet.2022.06.008","article-title":"Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8(+) T cells","volume":"34","author":"Elia","year":"2022","journal-title":"Cell Metab."},{"issue":"9","key":"10.1016\/j.bbcan.2026.189671_bb0565","doi-asserted-by":"crossref","first-page":"3354","DOI":"10.1073\/pnas.0802864106","article-title":"Inflammation and mitochondrial fatty acid beta-oxidation link obesity to early tumor promotion","volume":"106","author":"Khasawneh","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"4","key":"10.1016\/j.bbcan.2026.189671_bb0570","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/s41419-020-2426-z","article-title":"MSC-induced lncRNA HCP5 drove fatty acid oxidation through miR-3619-5p\/AMPK\/PGC1\u03b1\/CEBPB axis to promote stemness and chemo-resistance of gastric cancer","volume":"11","author":"Wu","year":"2020","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.bbcan.2026.189671_bb0575","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2023.216235","article-title":"MSC-NPRA loop drives fatty acid oxidation to promote stemness and chemoresistance of gastric cancer","volume":"565","author":"Chen","year":"2023","journal-title":"Cancer Lett."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0580","doi-asserted-by":"crossref","first-page":"2692","DOI":"10.1038\/s41467-023-38360-5","article-title":"Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer","volume":"14","author":"Sun","year":"2023","journal-title":"Nat. Commun."},{"issue":"3","key":"10.1016\/j.bbcan.2026.189671_bb0585","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20191226","article-title":"Inhibiting both proline biosynthesis and lipogenesis synergistically suppresses tumor growth","volume":"217","author":"Liu","year":"2020","journal-title":"J. Exp. Med."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0590","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.cmet.2019.11.010","article-title":"Greasing the wheels of the cancer machine: the role of lipid metabolism in Cancer","volume":"31","author":"Snaebjornsson","year":"2020","journal-title":"Cell Metab."},{"key":"10.1016\/j.bbcan.2026.189671_bb0595","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.769409","article-title":"Transcriptomic and metabolomic profiling in Helicobacter pylori-induced gastric Cancer identified prognosis- and immunotherapy-relevant gene signatures","volume":"9","author":"Liu","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0600","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.cmet.2019.04.002","article-title":"Cholesterol induces CD8(+) T cell exhaustion in the tumor microenvironment","volume":"30","author":"Ma","year":"2019","journal-title":"Cell Metab."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0605","doi-asserted-by":"crossref","first-page":"3770","DOI":"10.1186\/s12889-025-24888-2","article-title":"Spatiotemporal analysis of gastric cancer incidence in Iran from 2014 to 2018: a geospatial epidemiological study","volume":"25","author":"Soleimani","year":"2025","journal-title":"BMC Public Health"},{"key":"10.1016\/j.bbcan.2026.189671_bb0610","volume":"279","author":"Wang","year":"2021","journal-title":"J. Ethnopharmacol."},{"issue":"12","key":"10.1016\/j.bbcan.2026.189671_bb0615","doi-asserted-by":"crossref","first-page":"4135","DOI":"10.1111\/cas.15581","article-title":"m6A modification-mediated lncRNA TP53TG1 inhibits gastric cancer progression by regulating CIP2A stability","volume":"113","author":"Fang","year":"2022","journal-title":"Cancer Sci."},{"key":"10.1016\/j.bbcan.2026.189671_bb0620","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2021.109394","article-title":"Ginkgoic acid impedes gastric cancer cell proliferation, migration and EMT through inhibiting the SUMOylation of IGF-1R","volume":"337","author":"Liu","year":"2021","journal-title":"Chem. Biol. Interact."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0625","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1142\/S0192415X25500077","article-title":"The pharmacology and toxicology of Ginkgolic acids: secondary metabolites from Ginkgo biloba","volume":"53","author":"Shao","year":"2025","journal-title":"Am. J. Chin. Med."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0630","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1007\/s10620-019-05739-8","article-title":"IRF-2 inhibits gastric cancer invasion and migration by down-regulating MMP-1","volume":"65","author":"Chen","year":"2020","journal-title":"Dig. Dis. Sci."},{"key":"10.1016\/j.bbcan.2026.189671_bb0635","article-title":"Anticancer effect of Tanshinones on female breast cancer and gynecological cancer","volume":"12","author":"Jin","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.bbcan.2026.189671_bb0640","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.117791","article-title":"Diterpenoid tanshinones inhibit gastric cancer angiogenesis through the PI3K\/Akt\/mTOR signaling pathway","volume":"324","author":"Yu","year":"2024","journal-title":"J. Ethnopharmacol."},{"issue":"11","key":"10.1016\/j.bbcan.2026.189671_bb0645","doi-asserted-by":"crossref","first-page":"904","DOI":"10.2174\/1568009622666220705095403","article-title":"Dextran Sulfate inhibits angiogenesis and invasion of gastric cancer by interfering with M2-type macrophages polarization","volume":"22","author":"Guo","year":"2022","journal-title":"Curr. Cancer Drug Targets"},{"issue":"9","key":"10.1016\/j.bbcan.2026.189671_bb0650","doi-asserted-by":"crossref","first-page":"5400","DOI":"10.1245\/s10434-021-09645-0","article-title":"Amlodipine and verapamil, voltage-gated Ca(2+) channel inhibitors, suppressed the growth of gastric cancer stem cells","volume":"28","author":"Shiozaki","year":"2021","journal-title":"Ann. Surg. Oncol."},{"issue":"43","key":"10.1016\/j.bbcan.2026.189671_bb0655","doi-asserted-by":"crossref","first-page":"5619","DOI":"10.1038\/onc.2016.87","article-title":"All-trans retinoic acid targets gastric cancer stem cells and inhibits patient-derived gastric carcinoma tumor growth","volume":"35","author":"Nguyen","year":"2016","journal-title":"Oncogene"},{"issue":"10","key":"10.1016\/j.bbcan.2026.189671_bb0660","doi-asserted-by":"crossref","first-page":"922","DOI":"10.2174\/1566524020666201120113538","article-title":"OSI-027 alleviates oxaliplatin chemoresistance in gastric cancer cells by suppressing P-gp induction","volume":"21","author":"Xu","year":"2021","journal-title":"Curr. Mol. Med."},{"issue":"8","key":"10.1016\/j.bbcan.2026.189671_bb0665","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1007\/s13304-023-01638-w","article-title":"Comparison of proximal gastrectomy with double-flap technique and double-tract reconstruction for proximal early gastric cancer: a meta-analysis","volume":"75","author":"Huang","year":"2023","journal-title":"Updat. Surg."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0670","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s12957-021-02126-4","article-title":"Comparison of the overall survival of proximal and distal gastric cancer after gastrectomy: a systematic review and meta-analysis","volume":"19","author":"Xue","year":"2021","journal-title":"World J. Surg. Oncol."},{"issue":"5","key":"10.1016\/j.bbcan.2026.189671_bb0675","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/S1470-2045(18)30132-3","article-title":"Chemotherapy versus chemoradiotherapy after surgery and preoperative chemotherapy for resectable gastric cancer (CRITICS): an international, open-label, randomised phase 3 trial","volume":"19","author":"Cats","year":"2018","journal-title":"Lancet Oncol."},{"issue":"19","key":"10.1016\/j.bbcan.2026.189671_bb0680","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1056\/NEJMoa2405195","article-title":"Preoperative chemoradiotherapy for resectable gastric cancer","volume":"391","author":"Leong","year":"2024","journal-title":"N. Engl. J. Med."},{"issue":"7","key":"10.1016\/j.bbcan.2026.189671_bb0685","doi-asserted-by":"crossref","DOI":"10.3390\/biom11071022","article-title":"The relationship between diabetes mellitus and gastric cancer and the potential benefits of metformin: an extensive review of the literature","volume":"11","author":"Tseng","year":"2021","journal-title":"Biomolecules"},{"issue":"5","key":"10.1016\/j.bbcan.2026.189671_bb0690","doi-asserted-by":"crossref","first-page":"39","DOI":"10.21037\/cco-22-82","article-title":"The role of proximal gastrectomy in gastric cancer","volume":"11","author":"Hirata","year":"2022","journal-title":"Chin. Clin. Oncol."},{"issue":"24","key":"10.1016\/j.bbcan.2026.189671_bb0695","doi-asserted-by":"crossref","first-page":"2628","DOI":"10.3748\/wjg.v24.i24.2628","article-title":"Comparison between uncut roux-en-Y and roux-en-Y reconstruction after distal gastrectomy for gastric cancer: a meta-analysis","volume":"24","author":"Sun","year":"2018","journal-title":"World J. Gastroenterol."},{"issue":"12","key":"10.1016\/j.bbcan.2026.189671_bb0700","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1002\/cncr.32066","article-title":"Optimal management of gastroesophageal junction cancer","volume":"125","author":"Greally","year":"2019","journal-title":"Cancer"},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0705","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s40880-019-0349-9","article-title":"The Chinese Society of Clinical Oncology (CSCO): clinical guidelines for the diagnosis and treatment of gastric cancer","volume":"39","author":"Wang","year":"2019","journal-title":"Cancer Commun. (Lond.)"},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0710","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s13045-023-01451-3","article-title":"Gastric cancer treatment: recent progress and future perspectives","volume":"16","author":"Guan","year":"2023","journal-title":"J. Hematol. Oncol."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0715","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/cac2.12516","article-title":"The Chinese Society of Clinical Oncology (CSCO): clinical guidelines for the diagnosis and treatment of gastric cancer, 2023","volume":"44","author":"Wang","year":"2024","journal-title":"Cancer Commun. (Lond.)"},{"issue":"5","key":"10.1016\/j.bbcan.2026.189671_bb0720","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1038\/s41571-024-00874-2","article-title":"Claudin 18.2 as a novel therapeutic target","volume":"21","author":"Nakayama","year":"2024","journal-title":"Nat. Rev. Clin. Oncol."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0725","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1186\/s13045-017-0473-4","article-title":"Anti-claudin 18.2 antibody as new targeted therapy for advanced gastric cancer","volume":"10","author":"Singh","year":"2017","journal-title":"J. Hematol. Oncol."},{"issue":"8","key":"10.1016\/j.bbcan.2026.189671_bb0730","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1038\/s41591-023-02465-7","article-title":"Zolbetuximab plus CAPOX in CLDN18.2-positive gastric or gastroesophageal junction adenocarcinoma: the randomized, phase 3 GLOW trial","volume":"29","author":"Shah","year":"2023","journal-title":"Nat. Med."},{"issue":"2","key":"10.1016\/j.bbcan.2026.189671_bb0735","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1111\/his.13975","article-title":"The 2019 WHO classification of tumours of the digestive system","volume":"76","author":"Nagtegaal","year":"2020","journal-title":"Histopathology"},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0740","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s00423-021-02314-6","article-title":"Signet ring cell cancer of stomach and gastro-esophageal junction: molecular alterations, stage-stratified treatment approaches, and future challenges","volume":"407","author":"Kumar","year":"2022","journal-title":"Langenbeck\u2019s Arch. Surg."},{"issue":"4","key":"10.1016\/j.bbcan.2026.189671_bb0745","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.00391-2017","article-title":"What is precision medicine?","volume":"50","author":"K\u00f6nig","year":"2017","journal-title":"Eur. Respir. J."},{"issue":"1","key":"10.1016\/j.bbcan.2026.189671_bb0750","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1038\/s41392-024-01932-y","article-title":"Predicting gastric cancer response to anti-HER2 therapy or anti-HER2 combined immunotherapy based on multi-modal data","volume":"9","author":"Chen","year":"2024","journal-title":"Signal Transduct. Target. Ther."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Reviews on Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304419X26001435?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304419X26001435?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:24:41Z","timestamp":1789518281000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304419X26001435"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":150,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["S0304419X26001435"],"URL":"https:\/\/doi.org\/10.1016\/j.bbcan.2026.189671","relation":{},"ISSN":["0304-419X"],"issn-type":[{"value":"0304-419X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Temporal and spatial molecular heterogeneity of gastric cancer: Roles of post-translational modifications","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Reviews on Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbcan.2026.189671","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"189671"}}