{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T09:46:52Z","timestamp":1779356812785,"version":"3.51.4"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,11,25]],"date-time":"2016-11-25T00:00:00Z","timestamp":1480032000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain, Behavior, and Immunity"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1016\/j.bbi.2016.11.014","type":"journal-article","created":{"date-parts":[[2016,11,16]],"date-time":"2016-11-16T08:53:41Z","timestamp":1479286421000},"page":"155-164","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Influence of chronic L-DOPA treatment on immune response following allogeneic and xenogeneic graft in a rat model of Parkinson\u2019s disease"],"prefix":"10.1016","volume":"61","author":[{"given":"Ludivine S.","family":"Breger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Korbinian","family":"Kienle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaynor A.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen B.","family":"Dunnett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emma L.","family":"Lane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbi.2016.11.014_b0005","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1006\/exnr.1994.1204","article-title":"Chronic treatment with levodopa and\/or selegiline does not affect behavioral recovery induced by fetal ventral mesencephalic grafts in unilaterally 6-hydroxydopamine-lesioned rats","volume":"130","author":"Adams","year":"1994","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bbi.2016.11.014_b0010","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1046\/j.1365-2680.1999.00135.x","article-title":"Dopamine D2-like receptors on human peripheral blood lymphocytes: a radioligand binding assay and immunocytochemical study","volume":"19","author":"Amenta","year":"1999","journal-title":"J. Auton. Pharmacol."},{"key":"10.1016\/j.bbi.2016.11.014_b0015","article-title":"G-force PD: a global initiative in coordinating stem cell based dopamine treatments for Parkinson\u2019s disease","volume":"1","author":"Barker","year":"2015","journal-title":"npj Parkinson\u2019s Dis."},{"key":"10.1016\/j.bbi.2016.11.014_b0020","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1227\/01.NEU.0000129550.31643.54","article-title":"Functional improvement with low-dose dopaminergic grafts in hemiparkinsonian rats","volume":"55","author":"Bartlett","year":"2004","journal-title":"Neurosurgery"},{"key":"10.1016\/j.bbi.2016.11.014_b0025","first-page":"1","article-title":"Intracerebral grafting of neuronal cell suspensions. I. Introduction and general methods of preparation","volume":"522","author":"Bjorklund","year":"1983","journal-title":"Acta Physiol. Scand. Suppl."},{"key":"10.1016\/j.bbi.2016.11.014_b0030","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/S0079-6123(08)62639-4","article-title":"The effect of L-dopa and carbidopa on behavioural recovery produced by ventral mesencephalic grafts in rats","volume":"82","author":"Blunt","year":"1990","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.bbi.2016.11.014_b0035","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/0306-4522(91)90420-S","article-title":"The effect of L-dopa and carbidopa treatment on the survival of rat fetal dopamine grafts assessed by tyrosine hydroxylase immunohistochemistry and [3H]mazindol autoradiography","volume":"43","author":"Blunt","year":"1991","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbi.2016.11.014_b0040","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1007\/BF02259108","article-title":"Motor function, graft survival and gliosis in rats with 6-OHDA lesions and foetal ventral mesencephalic grafts chronically treated with L-dopa and carbidopa","volume":"88","author":"Blunt","year":"1992","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.bbi.2016.11.014_b0045","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1093\/biomet\/40.3-4.318","article-title":"Non-normality and tests on variances","volume":"40","author":"Box","year":"1953","journal-title":"Biometrika"},{"key":"10.1016\/j.bbi.2016.11.014_b0050","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.nbd.2012.10.013","article-title":"Comparison of rating scales used to evaluate L-DOPA-induced dyskinesia in the 6-OHDA lesioned rat","volume":"50","author":"Breger","year":"2013","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.bbi.2016.11.014_b0055","series-title":"An Atlas of Staging Mammalian and Chick Embryos","author":"Butler","year":"1987"},{"key":"10.1016\/j.bbi.2016.11.014_b0060","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.nbd.2005.09.008","article-title":"Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia","volume":"21","author":"Carlsson","year":"2006","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.bbi.2016.11.014_b0065","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1182\/blood-2006-01-028423","article-title":"Human CD4+CD25+ regulatory T cells selectively express tyrosine hydroxylase and contain endogenous catecholamines subserving an autocrine\/paracrine inhibitory functional loop","volume":"109","author":"Cosentino","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.bbi.2016.11.014_b0070","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/ana.410220105","article-title":"Multi-center study of Parkinson mortality with early versus later dopa treatment","volume":"22","author":"Diamond","year":"1987","journal-title":"Ann Neurol"},{"key":"10.1016\/j.bbi.2016.11.014_b0075","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0006-8993(81)90498-4","article-title":"Behavioural recovery following transplantation of substantia nigra in rats subjected to 6-OHDA lesions of the nigrostriatal pathway. I. Unilateral lesions","volume":"215","author":"Dunnett","year":"1981","journal-title":"Brain Res."},{"key":"10.1016\/j.bbi.2016.11.014_b0080","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1056\/NEJMoa033447","article-title":"Levodopa and the progression of Parkinson\u2019s disease","volume":"351","author":"Fahn","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.bbi.2016.11.014_b0085","series-title":"Animal Models of Movement Disorders","article-title":"Comparing behavioural assessment of sensorimotor function in rat and mouse models of Parkinson\u2019s disease","author":"Fleming","year":"2011"},{"key":"10.1016\/j.bbi.2016.11.014_b0090","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.expneurol.2011.09.017","article-title":"Extent of pre-operative L-DOPA-induced dyskinesia predicts the severity of graft-induced dyskinesia after fetal dopamine cell transplantation","volume":"232","author":"Garcia","year":"2011","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bbi.2016.11.014_b0095","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/0006-8993(90)91215-3","article-title":"Fetal dopamine neuron transplants prevent behavioral supersensitivity induced by repeated administration of L-dopa in the rat","volume":"506","author":"Gaudin","year":"1990","journal-title":"Brain Res."},{"issue":"Suppl 2","key":"10.1016\/j.bbi.2016.11.014_b0100","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1016\/j.surneu.2005.07.038","article-title":"Effects of intranigral vs intrastriatal fetal mesencephalic neural grafts on motor behavior disorders in a rat Parkinson model","volume":"64","author":"Goren","year":"2005","journal-title":"Surg. Neurol."},{"key":"10.1016\/j.bbi.2016.11.014_b0105","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1093\/jnen\/60.8.741","article-title":"Cell survival and clinical outcome following intrastriatal transplantation in Parkinson disease","volume":"60","author":"Hagell","year":"2001","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.bbi.2016.11.014_b0110","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1038\/nn863","article-title":"Dyskinesias following neural transplantation in Parkinson\u2019s disease","volume":"5","author":"Hagell","year":"2002","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbi.2016.11.014_b0115","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1001\/archneur.56.2.179","article-title":"Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease","volume":"56","author":"Hauser","year":"1999","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.bbi.2016.11.014_b0120","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1002\/(SICI)1097-0185(199803)250:3<373::AID-AR12>3.0.CO;2-L","article-title":"What was wrong with the Abercrombie and empirical cell counting methods? A review","volume":"250","author":"Hedreen","year":"1998","journal-title":"Anat. Rec."},{"key":"10.1016\/j.bbi.2016.11.014_b0125","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.expneurol.2013.01.020","article-title":"Dopamine-rich grafts alleviate deficits in contralateral response space induced by extensive dopamine depletion in rats","volume":"247","author":"Heuer","year":"2013","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bbi.2016.11.014_b0130","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1177\/096368979700600304","article-title":"Fetal grafting for Parkinson\u2019s disease: expression of immune markers in two patients with functional fetal nigral implants","volume":"6","author":"Kordower","year":"1997","journal-title":"Cell Transplant."},{"key":"10.1016\/j.bbi.2016.11.014_b0135","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1056\/NEJM199504273321702","article-title":"Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson\u2019s disease","volume":"332","author":"Kordower","year":"1995","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.bbi.2016.11.014_b0140","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3233\/JPD-2011-11004","article-title":"Signs of degeneration in 12\u201322-year old grafts of mesencephalic dopamine neurons in patients with Parkinson\u2019s disease","volume":"1","author":"Kurowska","year":"2011","journal-title":"J. Parkinsons Dis."},{"key":"10.1016\/j.bbi.2016.11.014_b0145","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.nbd.2005.11.011","article-title":"The impact of graft size on the development of dyskinesia following intrastriatal grafting of embryonic dopamine neurons in the rat","volume":"22","author":"Lane","year":"2006","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.bbi.2016.11.014_b0150","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.expneurol.2009.04.010","article-title":"Priming for L-DOPA-induced abnormal involuntary movements increases the severity of amphetamine-induced dyskinesia in grafted rats","volume":"219","author":"Lane","year":"2009","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bbi.2016.11.014_b0155","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1093\/brain\/123.7.1365","article-title":"Embryonic ventral mesencephalic grafts improve levodopa-induced dyskinesia in a rat model of Parkinson\u2019s disease","volume":"123","author":"Lee","year":"2000","journal-title":"Brain"},{"key":"10.1016\/j.bbi.2016.11.014_b0160","doi-asserted-by":"crossref","first-page":"6544","DOI":"10.1073\/pnas.1605245113","article-title":"Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain","volume":"113","author":"Li","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bbi.2016.11.014_b0165","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1038\/npp.2009.74","article-title":"Differential involvement of D1 and D2 dopamine receptors in L-DOPA-induced angiogenic activity in a rat model of Parkinson\u2019s disease","volume":"34","author":"Lindgren","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbi.2016.11.014_b0170","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1126\/science.250.4986.1435","article-title":"In reply: fetal brain grafts and Parkinson\u2019s disease","volume":"250","author":"Lindvall","year":"1990","journal-title":"Science"},{"key":"10.1016\/j.bbi.2016.11.014_b0175","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1126\/science.2105529","article-title":"Grafts of fetal dopamine neurons survive and improve motor function in Parkinson\u2019s disease","volume":"247","author":"Lindvall","year":"1990","journal-title":"Science"},{"key":"10.1016\/j.bbi.2016.11.014_b0180","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/S0165-5728(02)00280-1","article-title":"Dopamine receptor expression on human T- and B-lymphocytes, monocytes, neutrophils, eosinophils and NK cells: a flow cytometric study","volume":"132","author":"McKenna","year":"2002","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.bbi.2016.11.014_b0185","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1093\/brain\/awh510","article-title":"Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson\u2019s disease","volume":"128","author":"Mendez","year":"2005","journal-title":"Brain"},{"key":"10.1016\/j.bbi.2016.11.014_b0190","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/S0022-5223(96)70101-0","article-title":"The influence of concordant xenografts on the humoral and cell-mediated immune responses to subsequent allografts in primates","volume":"112","author":"Michler","year":"1996","journal-title":"J Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.bbi.2016.11.014_b0195","doi-asserted-by":"crossref","first-page":"671","DOI":"10.3233\/JPD-140432","article-title":"Which patients with Parkinson\u2019s disease participate in clinical trials? One centre\u2019s experiences with a new cell based therapy trial (TRANSEURO)","volume":"4","author":"Moore","year":"2014","journal-title":"J. Parkinsons Dis."},{"key":"10.1016\/j.bbi.2016.11.014_b0200","doi-asserted-by":"crossref","first-page":"3449","DOI":"10.1523\/JNEUROSCI.14-06-03449.1994","article-title":"Intranigral fetal dopamine grafts induce behavioral compensation in the rat Parkinson model","volume":"14","author":"Nikkhah","year":"1994","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2016.11.014_b0205","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.neuroimage.2012.02.066","article-title":"Impact of L-DOPA treatment on regional cerebral blood flow and metabolism in the basal ganglia in a rat model of Parkinson\u2019s disease","volume":"61","author":"Ohlin","year":"2012","journal-title":"Neuroimage"},{"key":"10.1016\/j.bbi.2016.11.014_b0210","doi-asserted-by":"crossref","first-page":"S24","DOI":"10.1212\/WNL.61.6_suppl_3.S24","article-title":"Present and future directions in the management of motor complications in patients with advanced PD","volume":"61","author":"Olanow","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.bbi.2016.11.014_b0215","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/mds.26119","article-title":"Levodopa: effect on cell death and the natural history of Parkinson\u2019s disease","volume":"30","author":"Olanow","year":"2015","journal-title":"Mov. Disord."},{"key":"10.1016\/j.bbi.2016.11.014_b0220","doi-asserted-by":"crossref","first-page":"3863","DOI":"10.1523\/JNEUROSCI.15-05-03863.1995","article-title":"Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test","volume":"15","author":"Olsson","year":"1995","journal-title":"J Neurosci"},{"key":"10.1016\/j.bbi.2016.11.014_b0225","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/mds.870010109","article-title":"Preservation of the substantia nigra and locus coeruleus in a patient receiving levodopa (2 kg) plus decarboxylase inhibitor over a four-year period","volume":"1","author":"Quinn","year":"1986","journal-title":"Mov. Disord."},{"key":"10.1016\/j.bbi.2016.11.014_b0230","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1002\/mds.870120503","article-title":"Is levodopa toxic to human substantia nigra?","volume":"12","author":"Rajput","year":"1997","journal-title":"Mov. Disord."},{"key":"10.1016\/j.bbi.2016.11.014_b0235","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0165-5728(94)90057-4","article-title":"Dopamine D5 receptors in human peripheral blood lymphocytes: a radioligand binding study","volume":"53","author":"Ricci","year":"1994","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.bbi.2016.11.014_b0240","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0165-5728(98)00207-0","article-title":"Labeling of dopamine D3 and D4 receptor subtypes in human peripheral blood lymphocytes with [3H]7-OH-DPAT: a combined radioligand binding assay and immunochemical study","volume":"92","author":"Ricci","year":"1998","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.bbi.2016.11.014_b0245","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/S0165-5728(99)00042-9","article-title":"Dopamine D1-like receptor subtypes in human peripheral blood lymphocytes","volume":"96","author":"Ricci","year":"1999","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.bbi.2016.11.014_b0250","doi-asserted-by":"crossref","first-page":"6077","DOI":"10.1016\/S0021-9258(18)53221-X","article-title":"Human P-glycoprotein transports cyclosporin A and FK506","volume":"268","author":"Saeki","year":"1993","journal-title":"J. Biol. Chem."},{"issue":"Suppl. 1","key":"10.1016\/j.bbi.2016.11.014_b0255","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1111\/j.1399-0039.2006.00802.x","article-title":"An apportionment of human HLA diversity","volume":"69","author":"Sanchez-Mazas","year":"2007","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.bbi.2016.11.014_b0260","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/0165-5728(93)90170-4","article-title":"Dopamine receptors on human T- and B-lymphocytes","volume":"45","author":"Santambrogio","year":"1993","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.bbi.2016.11.014_b0265","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.nbd.2008.06.018","article-title":"The synaptic impact of the host immune response in a parkinsonian allograft rat model: influence on graft-derived aberrant behaviors","volume":"32","author":"Soderstrom","year":"2008","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.bbi.2016.11.014_b0270","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/cne.22037","article-title":"Effect of levodopa priming on dopamine neuron transplant efficacy and induction of abnormal involuntary movements in parkinsonian rats","volume":"515","author":"Steece-Collier","year":"2009","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.bbi.2016.11.014_b0275","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1186\/s40478-015-0263-6","article-title":"Cyclosporin promotes neurorestoration and cell replacement therapy in pre-clinical models of Parkinson\u2019s disease","volume":"3","author":"Tamburrino","year":"2015","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.bbi.2016.11.014_b0280","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.jneumeth.2006.05.016","article-title":"An investigation of the problem of two-layered immunohistochemical staining in paraformaldehyde fixed sections","volume":"158","author":"Torres","year":"2006","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.bbi.2016.11.014_b0285","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1016\/j.neuroscience.2007.03.037","article-title":"Improved survival of young donor age dopamine grafts in a rat model of Parkinson\u2019s disease","volume":"146","author":"Torres","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbi.2016.11.014_b0290","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jneumeth.2011.06.012","article-title":"Increased efficacy of the 6-hydroxydopamine lesion of the median forebrain bundle in small rats, by modification of the stereotaxic coordinates","volume":"200","author":"Torres","year":"2011","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.bbi.2016.11.014_b0295","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/0006-8993(70)90187-3","article-title":"Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system","volume":"24","author":"Ungerstedt","year":"1970","journal-title":"Brain Res."},{"key":"10.1016\/j.bbi.2016.11.014_b0300","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.neulet.2008.06.055","article-title":"Interactions between antiparkinsonian drugs and ABCB1\/P-glycoprotein at the blood-brain barrier in a rat brain endothelial cell model","volume":"442","author":"Vautier","year":"2008","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.bbi.2016.11.014_b0305","doi-asserted-by":"crossref","first-page":"9448","DOI":"10.1523\/JNEUROSCI.0944-06.2006","article-title":"Endothelial proliferation and increased blood-brain barrier permeability in the basal ganglia in a rat model of 3,4-dihydroxyphenyl-L-alanine-induced dyskinesia","volume":"26","author":"Westin","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2016.11.014_b0310","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/BF00231044","article-title":"Chronic levodopa impairs the recovery of dopamine agonist-induced rotational behavior following neural grafting","volume":"86","author":"Yurek","year":"1991","journal-title":"Exp. Brain Res."}],"container-title":["Brain, Behavior, and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159116305165?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159116305165?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:44:01Z","timestamp":1760168641000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889159116305165"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":62,"alternative-id":["S0889159116305165"],"URL":"https:\/\/doi.org\/10.1016\/j.bbi.2016.11.014","relation":{},"ISSN":["0889-1591"],"issn-type":[{"value":"0889-1591","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Influence of chronic L-DOPA treatment on immune response following allogeneic and xenogeneic graft in a rat model of Parkinson\u2019s disease","name":"articletitle","label":"Article Title"},{"value":"Brain, Behavior, and Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbi.2016.11.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}