{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T02:17:57Z","timestamp":1790734677810,"version":"4.1.0"},"reference-count":90,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2011\/20343-4"],"award-info":[{"award-number":["2011\/20343-4"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2012\/04237-2"],"award-info":[{"award-number":["2012\/04237-2"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2013\/08216-2"],"award-info":[{"award-number":["2013\/08216-2"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2013\/20549-7"],"award-info":[{"award-number":["2013\/20549-7"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2015\/20463-0"],"award-info":[{"award-number":["2015\/20463-0"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["142068\/2012-8"],"award-info":[{"award-number":["142068\/2012-8"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain, Behavior, and Immunity"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1016\/j.bbi.2017.04.003","type":"journal-article","created":{"date-parts":[[2017,4,7]],"date-time":"2017-04-07T03:17:11Z","timestamp":1491535031000},"page":"330-343","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":93,"special_numbering":"C","title":["Modulation of experimental arthritis by vagal sensory and central brain stimulation"],"prefix":"10.1016","volume":"64","author":[{"given":"Gabriel Shimizu","family":"Bassi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel Penteado Martins","family":"Dias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo","family":"Franchin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jhimmy","family":"Talbot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel Gustavo","family":"Reis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo Batista","family":"Menezes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaci Airton","family":"Castania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norberto","family":"Garcia-Cairasco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo Barbosa Moraes","family":"Resstel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helio Cesar","family":"Salgado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando Queir\u00f3z","family":"Cunha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thiago Mattar","family":"Cunha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Ulloa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Kanashiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbi.2017.04.003_b0005","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1152\/ajpheart.00557.2015","article-title":"Central-peripheral neural network interactions evoked by vagus nerve stimulation: functional consequences on control of cardiac function","volume":"309","author":"Ardell","year":"2015","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bbi.2017.04.003_b0010","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1159\/000144411","article-title":"Functional anatomy of canine cardiac nerves","volume":"91","author":"Armour","year":"1975","journal-title":"Acta Anat. (Basel)"},{"key":"10.1016\/j.bbi.2017.04.003_b0015","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/j.1742-7843.2011.00824.x","article-title":"Lipopolysaccharide-induced sickness behaviour evaluated in different models of anxiety and innate fear in rats","volume":"110","author":"Bassi","year":"2012","journal-title":"Basic Clin. Pharmacol. Toxicol."},{"key":"10.1016\/j.bbi.2017.04.003_b0020","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.bbi.2015.05.002","article-title":"Baroreflex activation in conscious rats modulates the joint inflammatory response via sympathetic function","volume":"49","author":"Bassi","year":"2015","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbi.2017.04.003_b0025","series-title":"The Wiley-Blackwell Handbook of Psychoneuroimmunology","first-page":"24","article-title":"Innervation of the Immune System","author":"Bellinger","year":"2013"},{"key":"10.1016\/j.bbi.2017.04.003_b0030","doi-asserted-by":"crossref","first-page":"3242","DOI":"10.1002\/eji.1830231230","article-title":"Beta 2-adrenergic stimulation causes detachment of natural killer cells from cultured endothelium","volume":"23","author":"Benschop","year":"1993","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.bbi.2017.04.003_b0040","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1038\/35013070","article-title":"Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin","volume":"405","author":"Borovikova","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.bbi.2017.04.003_b0045","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1113\/expphysiol.2011.061531","article-title":"Neural regulation of inflammation: no neural connection from the vagus to splenic sympathetic neurons","volume":"97","author":"Bratton","year":"2012","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.bbi.2017.04.003_b0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/cne.1331","article-title":"Characterization of the central nervous system innervation of the rat spleen using viral transneuronal tracing","volume":"439","author":"Cano","year":"2001","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.bbi.2017.04.003_b0055","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1113\/expphysiol.2013.075192","article-title":"Cortical control of the autonomic nervous system","volume":"99","author":"Cechetto","year":"2014","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.bbi.2017.04.003_b0060","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0167-5699(91)90093-9","article-title":"Autoimmunity, microbial immunity and the immunological homunculus","volume":"12","author":"Cohen","year":"1991","journal-title":"Immunol. Today"},{"key":"10.1016\/j.bbi.2017.04.003_b0065","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0006-8993(80)90466-7","article-title":"Evidence against specificity of electrical stimulation of the nucleus locus coeruleus in activating the sympathetic nervous system in the rat","volume":"183","author":"Crawley","year":"1980","journal-title":"Brain Res."},{"key":"10.1016\/j.bbi.2017.04.003_b0070","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1038\/sj.npp.1301570","article-title":"Induction of c-Fos and DeltaFosB immunoreactivity in rat brain by Vagal nerve stimulation","volume":"33","author":"Cunningham","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbi.2017.04.003_b0075","article-title":"Effect of Electroacupuncture in \u201cZusanli\u201d and \u201cKunlun\u201d Acupoints on TLR4 Signaling Pathway of Adjuvant Arthritis Rats","volume":"1","author":"Dong","year":"2016","journal-title":"Am. J .Ther."},{"key":"10.1016\/j.bbi.2017.04.003_b0080","first-page":"469","article-title":"Anti-tumor necrosis factor (TNF) therapy in rheumatoid arthritis: correlation of TNF-alpha serum level with clinical response and benefit from changing dose or frequency of infliximab infusions","volume":"23","author":"Edrees","year":"2005","journal-title":"Clin. Exp. Rheumatol."},{"key":"10.1016\/j.bbi.2017.04.003_b0085","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.autrev.2008.11.002","article-title":"Serious infections during anti-TNF treatment in rheumatoid arthritis patients","volume":"8","author":"Favalli","year":"2009","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.bbi.2017.04.003_b0090","doi-asserted-by":"crossref","DOI":"10.1002\/0471142301.ns0803s26","article-title":"Animal tests of anxiety","author":"File","year":"2004","journal-title":"Curr. Protoc. Neurosci."},{"key":"10.1016\/j.bbi.2017.04.003_b0095","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/nature18626","article-title":"Unexpected role of interferon- in regulating neuronal connectivity and social behaviour","volume":"535","author":"Filiano","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.bbi.2017.04.003_b0100","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/nature01661","article-title":"Evolving concepts of rheumatoid arthritis","volume":"423","author":"Firestein","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.bbi.2017.04.003_b0105","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1002\/cne.22283","article-title":"Paraventricular hypothalamic nucleus: Axonal projections to the brainstem","volume":"518","author":"Geerling","year":"2010","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.bbi.2017.04.003_b0110","doi-asserted-by":"crossref","first-page":"PL321","DOI":"10.1016\/0024-3205(94)00771-3","article-title":"Characterization of zymosan-induced arthritis in the rat: effects on joint inflammation and cartilage metabolism","volume":"55","author":"Gegout","year":"1994","journal-title":"Life Sci."},{"key":"10.1016\/j.bbi.2017.04.003_b0115","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/0031-9384(90)90025-Y","article-title":"Thermal biology of the laboratory rat","volume":"47","author":"Gordon","year":"1990","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.bbi.2017.04.003_b0120","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.neulet.2004.12.055","article-title":"Recordings from the rat locus coeruleus during acute vagal nerve stimulation in the anaesthetised rat","volume":"379","author":"Groves","year":"2005","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.bbi.2017.04.003_b9000","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1146\/annurev.ne.04.030181.000441","article-title":"Calcium channel","volume":"4","author":"Hagiwara","year":"1981","journal-title":"Ann. Rev. Neurosci."},{"key":"10.1016\/j.bbi.2017.04.003_b0125","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1002\/ar.1092290415","article-title":"Anatomy of the rat knee joint and fibre composition of a major articular nerve","volume":"229","author":"Hildebrand","year":"1991","journal-title":"Anat. Rec."},{"key":"10.1016\/j.bbi.2017.04.003_b0130","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1002\/cne.902600109","article-title":"Some anatomical observations on the projections from the hypothalamus to brainstem and spinal cord: an HRP and autoradiographic tracing study in the cat","volume":"260","author":"Holstege","year":"1987","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.bbi.2017.04.003_b0135","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/BF00229982","article-title":"Descending input from the hypothalamic paraventricular nucleus to sympathetic preganglionic neurons in the rat","volume":"85","author":"Hosoya","year":"1991","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.bbi.2017.04.003_b0140","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0304-3940(91)90581-D","article-title":"Stimulation of lumbar sympathetic trunk produces vasoconstriction of the vasa nervorum in the sciatic nerve via \u2013 adrenergic receptors in rats","volume":"133","author":"Hotta","year":"1991","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.bbi.2017.04.003_b0145","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1084\/jem.20052362","article-title":"Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis","volume":"203","author":"Huston","year":"2006","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.bbi.2017.04.003_b0150","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s00296-006-0165-9","article-title":"Serious infections under treatment with TNF- antagonists compared to traditional DMARDs in patients with rheumatoid arthritis","volume":"27","author":"Inanc","year":"2006","journal-title":"Rheumatol. Int."},{"key":"10.1016\/j.bbi.2017.04.003_b0155","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1172\/JCI83658","article-title":"Vagus nerve stimulation mediates protection from kidney ischemia-reperfusion injury through 7nAChR+. splenocytes","volume":"126","author":"Inoue","year":"2016","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbi.2017.04.003_b0160","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1177\/1759720X16665330","article-title":"Combination therapy with biologic agents in rheumatic diseases: current and future prospects","volume":"8","author":"Inui","year":"2016","journal-title":"Ther. Adv. Musculoskeletal Dis."},{"key":"10.1016\/j.bbi.2017.04.003_b0165","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.autneu.2014.01.004","article-title":"Sympathetic nervous system and inflammation: a conceptual view","volume":"182","author":"Janig","year":"2014","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.bbi.2017.04.003_b0170","doi-asserted-by":"crossref","first-page":"R101","DOI":"10.1186\/ar3826","article-title":"Sensory and sympathetic nerve fibers undergo sprouting and neuroma formation in the painful arthritic joint of geriatric mice","volume":"14","author":"Jimenez-Andrade","year":"2012","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.bbi.2017.04.003_b0175","first-page":"1325","article-title":"Increase in sympathetic outflow by paraventricular nucleus stimulation in awake rats","volume":"256","author":"Kannan","year":"1989","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.bbi.2017.04.003_b0180","doi-asserted-by":"crossref","first-page":"e114498","DOI":"10.1371\/journal.pone.0114498","article-title":"Vagal nerve stimulation therapy: what is being stimulated?","volume":"9","author":"Kember","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1016\/j.bbi.2017.04.003_b0185","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1002\/art.1780200714","article-title":"Zymosan\u2014induced arthritis","volume":"20","author":"Keystone","year":"1977","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.bbi.2017.04.003_b0190","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/nri3399","article-title":"Neutrophil recruitment and function in health and inflammation","volume":"13","author":"Kolaczkowska","year":"2013","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bbi.2017.04.003_b0195","doi-asserted-by":"crossref","first-page":"8284","DOI":"10.1073\/pnas.1605635113","article-title":"Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis","volume":"113","author":"Koopman","year":"2016","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"2","key":"10.1016\/j.bbi.2017.04.003_b9005","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0165-0270(84)90030-X","article-title":"Local cobalt injection: a method to discriminate presynaptic axonal from postsynaptic neuronal activity","volume":"11","author":"Kretz","year":"1984","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.bbi.2017.04.003_b0200","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1159\/000126709","article-title":"Expression of c-fos protein in rat brain elicited by electrical and chemical stimulation of the hypothalamic paraventricular nucleus","volume":"59","author":"Krukoff","year":"2008","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.bbi.2017.04.003_b0205","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1177\/147323000403200503","article-title":"Beta2-adrenergic receptor stimulation-induced immunosuppressive effects possibly through down-regulation of co-stimulatory molecules, ICAM-1, CD40 and CD14 on monocytes","volume":"32","author":"Kuroki","year":"2004","journal-title":"J. Int. Med. Res."},{"key":"10.1016\/j.bbi.2017.04.003_b0210","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0304-3959(00)00412-7","article-title":"Bee venom injection into an acupuncture point reduces arthritis associated edema and nociceptive responses","volume":"90","author":"Kwon","year":"2001","journal-title":"Pain"},{"key":"10.1016\/j.bbi.2017.04.003_b0215","doi-asserted-by":"crossref","first-page":"e104530","DOI":"10.1371\/journal.pone.0104530","article-title":"Neurostimulation of the cholinergic anti-inflammatory pathway ameliorates disease in rat collagen-induced arthritis","volume":"9","author":"Levine","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1016\/j.bbi.2017.04.003_b0220","first-page":"26","article-title":"Targeting NF-\u03baB and TNF-\u03b1 activation by electroacupuncture to suppress collagen-induced rheumatoid arthritis in model rats","volume":"21","author":"Li","year":"2015","journal-title":"Altern. Ther. Health Med."},{"key":"10.1016\/j.bbi.2017.04.003_b0225","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/0006-8993(85)90554-2","article-title":"The course of paraventricular hypothalamic efferents to autonomic structures in medulla and spinal cord","volume":"329","author":"Luiten","year":"1985","journal-title":"Brain Res."},{"key":"10.1016\/j.bbi.2017.04.003_b0230","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0306-4522(02)00165-3","article-title":"Origins of skeletal pain: sensory and sympathetic innervation of the mouse femur","volume":"113","author":"Mach","year":"2002","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbi.2017.04.003_b0235","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1038\/nri3024","article-title":"Neutrophils in the activation and regulation of innate and adaptive immunity","volume":"11","author":"Mantovani","year":"2011","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bbi.2017.04.003_b0240","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1152\/ajpregu.00259.2014","article-title":"Reflex control of inflammation by the splanchnic anti-inflammatory pathway is sustained and independent of anesthesia","volume":"307","author":"Martelli","year":"2014","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.bbi.2017.04.003_b0245","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1136\/gutjnl-2013-304676","article-title":"A distinct vagal anti-inflammatory pathway modulates intestinal muscularis resident macrophages independent of the spleen","volume":"63","author":"Matteoli","year":"2013","journal-title":"Gut"},{"key":"10.1016\/j.bbi.2017.04.003_b0250","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0163-7258(90)90092-G","article-title":"Beta-blockers and central nervous system side effects","volume":"46","author":"McAinsh","year":"1990","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.bbi.2017.04.003_b0255","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1152\/jn.1997.78.3.1285","article-title":"Inhibition of bradykinin-induced plasma extravasation produced by noxious cutaneous and visceral stimuli and its modulation by vagal activity","volume":"78","author":"Miao","year":"1997","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.bbi.2017.04.003_b0260","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1113\/jphysiol.1997.sp021873","article-title":"Vagal branches involved in inhibition of bradykinin-induced synovial plasma extravasation by intrathecal nicotine and noxious stimulation in the rat","volume":"498","author":"Miao","year":"1997","journal-title":"J. Physiol."},{"key":"10.1016\/j.bbi.2017.04.003_b0265","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1136\/ard.40.2.171","article-title":"Role of polymorphs in inflammatory cartilage destruction in adjuvant arthritis of rats","volume":"40","author":"Mohr","year":"1981","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.bbi.2017.04.003_b0270","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1126\/science.3037702","article-title":"Mapping patterns of c-fos expression in the central nervous system after seizure","volume":"237","author":"Morgan","year":"1987","journal-title":"Science"},{"key":"10.1016\/j.bbi.2017.04.003_b0275","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1002\/art.27425","article-title":"Is the incidence of rheumatoid arthritis rising?: Results from Olmsted County, Minnesota, 1955\u20132007","volume":"62","author":"Myasoedova","year":"2010","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.bbi.2017.04.003_b0280","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/j.bbi.2007.03.008","article-title":"Autonomic innervation and regulation of the immune system (1987\u20132007)","volume":"21","author":"Nance","year":"2007","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbi.2017.04.003_b0285","doi-asserted-by":"crossref","first-page":"e52","DOI":"10.1016\/j.bbi.2005.10.108","article-title":"The immunomodulatory effects of counter-irritation are mediated via the sympathetic nervous system","volume":"19","author":"Nance","year":"2005","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbi.2017.04.003_b0290","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0920-1211(95)00035-9","article-title":"Regional induction of fos immunoreactivity in the brain by anticonvulsant stimulation of the vagus nerve","volume":"22","author":"Naritoku","year":"1995","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.bbi.2017.04.003_b0295","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1016\/S0735-1097(96)00393-2","article-title":"Cardiovascular effects of exercise: role of endothelial shear stress","volume":"28","author":"Niebauer","year":"1996","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.bbi.2017.04.003_b0300","doi-asserted-by":"crossref","first-page":"37","DOI":"10.15424\/bioelectronmed.2015.00006","article-title":"Single-pulse and unidirectional electrical activation of the cervical vagus nerve reduces tumor necrosis factor in endotoxemia","volume":"2","author":"Olofsson","year":"2015","journal-title":"Bioelectron. Med."},{"issue":"1","key":"10.1016\/j.bbi.2017.04.003_b9010","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1111\/j.1600-065X.2012.01138.x","article-title":"Rethinking inflammation: neural circuits in the regulation of immunity","volume":"248","author":"Olofsson","year":"2012","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.bbi.2017.04.003_b0305","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/0006-8993(92)90635-M","article-title":"Cholecystokinin induces c-fos expression in hypothalamic oxytocinergic neurons projecting to the dorsal vagal complex","volume":"569","author":"Olson","year":"1992","journal-title":"Brain Res."},{"key":"10.1016\/j.bbi.2017.04.003_b0310","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.hrthm.2012.12.015","article-title":"Sympathetic nerve fibers and ganglia in canine cervical vagus nerves: localization and quantitation","volume":"10","author":"Onkka","year":"2013","journal-title":"Heart Rhythm."},{"key":"10.1016\/j.bbi.2017.04.003_b0315","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.it.2015.08.007","article-title":"The regulation of immunological processes by peripheral neurons in homeostasis and disease","volume":"36","author":"Ordovas-Montanes","year":"2015","journal-title":"Trends Immunol."},{"key":"10.1016\/j.bbi.2017.04.003_b0320","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.jneuroim.2009.12.007","article-title":"Noradrenaline reuptake inhibitors inhibit expression of chemokines IP-10 and RANTES and cell adhesion molecules VCAM-1 and ICAM-1 in the CNS following a systemic inflammatory challenge","volume":"220","author":"OSullivan","year":"2010","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.bbi.2017.04.003_b0325","series-title":"The Rat Brain in Stereotaxic Coordinates: Hard Cover Edition","author":"Paxinos","year":"2006"},{"key":"10.1016\/j.bbi.2017.04.003_b0330","doi-asserted-by":"crossref","first-page":"718","DOI":"10.4049\/jimmunol.1100013","article-title":"Cholinergic regulatory lymphocytes re-establish neuromodulation of innate immune responses in sepsis","volume":"187","author":"Pe\u00f1a","year":"2011","journal-title":"J. Immunol."},{"key":"10.1016\/j.bbi.2017.04.003_b0335","series-title":"The Polyvagal Theory : Neurophysiological Foundations of Emotions, Attachment, Communication, and Self-regulation","author":"Porges","year":"2011"},{"key":"10.1016\/j.bbi.2017.04.003_b0340","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0079-6123(08)63803-0","article-title":"The projections of locus coeruleus neurons to the spinal cord","volume":"88","author":"Proudfit","year":"1991","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.bbi.2017.04.003_b0345","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1006\/brbi.1997.0498","article-title":"Dynamic exercise leads to an increase in circulating ICAM-1: further evidence for adrenergic modulation of cell adhesion","volume":"11","author":"Rehman","year":"1997","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbi.2017.04.003_b0350","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0006-8993(78)91125-3","article-title":"Anatomical evidence of direct projections from the nucleus of the solitary tract to the hypothalamus, amygdala, and other forebrain structures in the rat","volume":"153","author":"Ricardo","year":"1978","journal-title":"Brain Res."},{"key":"10.1016\/j.bbi.2017.04.003_b0355","doi-asserted-by":"crossref","first-page":"11008","DOI":"10.1073\/pnas.0803237105","article-title":"Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia","volume":"105","author":"Rosas-Ballina","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bbi.2017.04.003_b0360","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1126\/science.1209985","article-title":"Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit","volume":"334","author":"Rosas-Ballina","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.bbi.2017.04.003_b0365","doi-asserted-by":"crossref","first-page":"235","DOI":"10.2174\/157015908785777229","article-title":"Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part I: principles of functional organisation","volume":"6","author":"Samuels","year":"2008","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.bbi.2017.04.003_b0370","doi-asserted-by":"crossref","DOI":"10.1007\/BF00255242","article-title":"The use of local anaesthetic microinjections to identify central pathways: a quantitative evaluation of the time course and extent of the neuronal block","volume":"68","author":"Sandkuhler","year":"1987","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.bbi.2017.04.003_b0375","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.autneu.2013.12.004","article-title":"Function of the sympathetic supply in acute and chronic experimental joint inflammation","volume":"182","author":"Schaible","year":"2014","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.bbi.2017.04.003_b0380","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/0006-8993(94)01451-M","article-title":"C-fos immunoreactivity in the brain following electrical or chemical stimulation of the medial hypothalamus of freely moving rats","volume":"674","author":"Silveira","year":"1995","journal-title":"Brain Res."},{"key":"10.1016\/j.bbi.2017.04.003_b0385","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1749-6632.2012.06633.x","article-title":"Glucocorticoid regulation of inflammation and its functional correlates: from HPA axis to glucocorticoid receptor dysfunction","volume":"1261","author":"Silverman","year":"2012","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.bbi.2017.04.003_b0390","doi-asserted-by":"crossref","first-page":"R45","DOI":"10.1186\/ar2404","article-title":"A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis","volume":"10","author":"Smitten","year":"2008","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.bbi.2017.04.003_b0395","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/S1357-2725(03)00259-0","article-title":"Rheumatoid arthritis: regulation of synovial inflammation","volume":"36","author":"Sweeney","year":"2004","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.bbi.2017.04.003_b0400","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/nm.3479","article-title":"Dopamine mediates vagal modulation of the immune system by electroacupuncture","volume":"20","author":"Torres-Rosas","year":"2014","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbi.2017.04.003_b0405","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1172\/JCI30555","article-title":"Physiology and immunology of the cholinergic antiinflammatory pathway","volume":"117","author":"Tracey","year":"2007","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbi.2017.04.003_b0410","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1038\/nrd1797","article-title":"The vagus nerve and the nicotinic anti-inflammatory pathway","volume":"4","author":"Ulloa","year":"2005","journal-title":"Nat. Rev. Drug Discovery"},{"key":"10.1016\/j.bbi.2017.04.003_b0415","doi-asserted-by":"crossref","first-page":"vi28","DOI":"10.1093\/rheumatology\/kes278","article-title":"Evolution of treatment for rheumatoid arthritis","volume":"51","author":"Upchurch","year":"2012","journal-title":"Rheumatology"},{"key":"10.1016\/j.bbi.2017.04.003_b0420","article-title":"Morphology of the human cervical vagus nerve: implications for vagus nerve stimulation treatment","author":"Verlinden","year":"2015","journal-title":"Acta Neurol. Scand."},{"key":"10.1016\/j.bbi.2017.04.003_b0425","doi-asserted-by":"crossref","first-page":"4340","DOI":"10.4049\/jimmunol.1003722","article-title":"\u03917-cholinergic receptor mediates vagal induction of splenic norepinephrine","volume":"186","author":"Vida","year":"2011","journal-title":"J. Immunol."},{"key":"10.1016\/j.bbi.2017.04.003_b0430","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1038\/nm1124","article-title":"Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis","volume":"10","author":"Wang","year":"2004","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbi.2017.04.003_b0435","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/0304-3940(81)90399-2","article-title":"Origins of spinal noradrenergic pathways demonstrated by retrograde transport of antibody to dopamine-beta-hydroxylase","volume":"25","author":"Westlund","year":"1981","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.bbi.2017.04.003_b0440","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1038\/nrrheum.2014.80","article-title":"The multifactorial role of neutrophils in rheumatoid arthritis","volume":"10","author":"Wright","year":"2014","journal-title":"Nat. Rev. Rheumatol."}],"container-title":["Brain, Behavior, and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159117301046?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159117301046?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T21:29:11Z","timestamp":1740432551000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889159117301046"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":90,"alternative-id":["S0889159117301046"],"URL":"https:\/\/doi.org\/10.1016\/j.bbi.2017.04.003","relation":{},"ISSN":["0889-1591"],"issn-type":[{"value":"0889-1591","type":"print"}],"subject":[],"published":{"date-parts":[[2017,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Modulation of experimental arthritis by vagal sensory and central brain stimulation","name":"articletitle","label":"Article Title"},{"value":"Brain, Behavior, and Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbi.2017.04.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}