{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T17:31:47Z","timestamp":1762018307930,"version":"build-2065373602"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain, Behavior, and Immunity"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1016\/j.bbi.2020.07.039","type":"journal-article","created":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T12:10:09Z","timestamp":1596283809000},"page":"47-54","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Association of thyroid peroxidase antibodies with anti-neuronal surface antibodies in health, depression and schizophrenia \u2013 Complementary linkage with somatic symptoms of major depression"],"prefix":"10.1016","volume":"90","author":[{"given":"Johann","family":"Steiner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kolja","family":"Schiltz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Winfried","family":"Stoecker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bianca","family":"Teegen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik","family":"Dobrowolny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"Meyer-Lotz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malte","family":"Pennewitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrin","family":"Borucki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Frodl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Gert","family":"Bernstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbi.2020.07.039_b0005","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1192\/pb.21.4.224","article-title":"Chlorpromazine equivalents: a consensus of opinion for both clinical and research applications","volume":"21","author":"Atkins","year":"1997","journal-title":"Psychiatr. Bull."},{"key":"10.1016\/j.bbi.2020.07.039_b0010","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1111\/eip.12873","article-title":"Association between anti- thyroid antibodies and negative symptoms in early psychosis","volume":"14","author":"Barbero","year":"2020","journal-title":"Early Interv. Psychiatry"},{"key":"10.1016\/j.bbi.2020.07.039_b0015","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1176\/appi.ajp.2011.11030516","article-title":"Autoimmune diseases and severe infections as risk factors for schizophrenia: a 30-year population-based register study","volume":"168","author":"Benros","year":"2011","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.bbi.2020.07.039_b0020","first-page":"1","article-title":"Autoimmune diseases and severe infections as risk factors for mood disorders: a nationwide study","author":"Benros","year":"2013","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.bbi.2020.07.039_b0025","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.schres.2014.03.035","article-title":"Glial cells as key players in schizophrenia pathology: recent insights and concepts of therapy","volume":"161","author":"Bernstein","year":"2015","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.bbi.2020.07.039_b0030","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jneuroim.2007.08.012","article-title":"Anti-thyroperoxidase antibodies from patients with Hashimoto's encephalopathy bind to cerebellar astrocytes","volume":"192","author":"Blanchin","year":"2007","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.bbi.2020.07.039_b0035","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1002\/ana.24545","article-title":"The brain as immunoprecipitator of serum autoantibodies against N-Methyl-D-aspartate receptor subunit NR1","volume":"79","author":"Castillo-Gomez","year":"2016","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.bbi.2020.07.039_b0040","article-title":"All naturally occurring autoantibodies against the NMDA receptor subunit NR1 have pathogenic potential irrespective of epitope and immunoglobulin class","author":"Castillo-Gomez","year":"2016","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.bbi.2020.07.039_b0045","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.neulet.2012.10.060","article-title":"Anti-glutamate receptor epsilon2 antibodies in psychiatric patients with anti-thyroid autoantibodies\u2013a prevalence study in Japan","volume":"534","author":"Chiba","year":"2013","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.bbi.2020.07.039_b0050","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1001\/archneur.60.2.164","article-title":"Hashimoto encephalopathy: syndrome or myth?","volume":"60","author":"Chong","year":"2003","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.bbi.2020.07.039_b0055","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1002\/ana.24189","article-title":"Seroprevalence of autoantibodies against brain antigens in health and disease","volume":"76","author":"Dahm","year":"2014","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.bbi.2020.07.039_b0060","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S1474-4422(10)70253-2","article-title":"Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis","volume":"10","author":"Dalmau","year":"2011","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.bbi.2020.07.039_b0065","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1056\/NEJM199607113350206","article-title":"Chronic autoimmune thyroiditis","volume":"335","author":"Dayan","year":"1996","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.bbi.2020.07.039_b0070","doi-asserted-by":"crossref","first-page":"181","DOI":"10.3389\/fimmu.2017.00181","article-title":"Autoantibodies against the N-Methyl-d-aspartate receptor subunit NR1: untangling apparent inconsistencies for clinical practice","volume":"8","author":"Ehrenreich","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbi.2020.07.039_b0075","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1176\/appi.neuropsych.16110296","article-title":"Intrathecal thyroid autoantibody synthesis in a subgroup of patients with schizophreniform syndromes","volume":"29","author":"Endres","year":"2017","journal-title":"J. Neuropsychiatry Clin. Neurosci."},{"key":"10.1016\/j.bbi.2020.07.039_b0080","doi-asserted-by":"crossref","first-page":"476","DOI":"10.3389\/fnhum.2015.00476","article-title":"Immunological findings in psychotic syndromes: a tertiary care hospital\u2019s CSF sample of 180 patients","volume":"9","author":"Endres","year":"2015","journal-title":"Front. Hum. Neurosci."},{"key":"10.1016\/j.bbi.2020.07.039_b0085","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.jpsychores.2005.04.002","article-title":"Thyroid autoimmunity, depression and anxiety; are there any connections? an epidemiological study of a large population","volume":"59","author":"Engum","year":"2005","journal-title":"J. Psychosom. Res."},{"key":"10.1016\/j.bbi.2020.07.039_b0090","doi-asserted-by":"crossref","first-page":"73","DOI":"10.3109\/08039488.2014.929741","article-title":"Well-being and depression in individuals with subclinical hypothyroidism and thyroid autoimmunity \u2013 a general population study","volume":"69","author":"Fjaellegaard","year":"2015","journal-title":"Nord. J. Psychiatry"},{"key":"10.1016\/j.bbi.2020.07.039_b0095","doi-asserted-by":"crossref","first-page":"881","DOI":"10.4065\/mcp.2010.0326","article-title":"Autoimmune dementia: clinical course and predictors of immunotherapy response","volume":"85","author":"Flanagan","year":"2010","journal-title":"Mayo Clin. Proc."},{"key":"10.1016\/j.bbi.2020.07.039_b0100","doi-asserted-by":"crossref","first-page":"521","DOI":"10.3389\/fimmu.2017.00521","article-title":"Thyroid autoimmunity: role of anti-thyroid antibodies in thyroid and extra-thyroidal diseases","volume":"8","author":"Fr\u00f6hlich","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbi.2020.07.039_b0105","doi-asserted-by":"crossref","unstructured":"Frunza-Stefan, S., Whitlatch, H.B., Rao, G.G., Malek, R., 2018. Unusual case of anti-N-methyl-D-aspartic acid-receptor (NMDA-R) encephalitis and autoimmune polyglandular syndrome (APS). BMJ Case Rep., 2018.","DOI":"10.1136\/bcr-2018-224821"},{"key":"10.1016\/j.bbi.2020.07.039_b0110","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S1474-4422(15)00401-9","article-title":"A clinical approach to diagnosis of autoimmune encephalitis","volume":"15","author":"Graus","year":"2016","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.bbi.2020.07.039_b0115","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S1474-4422(13)70282-5","article-title":"Antibody titres at diagnosis and during follow-up of anti-NMDA receptor encephalitis: a retrospective study","volume":"13","author":"Gresa-Arribas","year":"2014","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.bbi.2020.07.039_b0120","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1002\/(SICI)1520-6394(1997)5:2<91::AID-DA5>3.0.CO;2-8","article-title":"Prevalence of antithyroid antibodies in mood disorders","volume":"5","author":"Haggerty","year":"1997","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.bbi.2020.07.039_b0125","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1038\/mp.2013.110","article-title":"Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood-brain barrier integrity","volume":"19","author":"Hammer","year":"2014","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.bbi.2020.07.039_b0130","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.jad.2015.03.021","article-title":"Dose equivalents of antidepressants: evidence-based recommendations from randomized controlled trials","volume":"180","author":"Hayasaka","year":"2015","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.bbi.2020.07.039_b0135","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1210\/jcem.87.2.8182","article-title":"Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)","volume":"87","author":"Hollowell","year":"2002","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.bbi.2020.07.039_b0140","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1007\/s00127-015-1043-0","article-title":"Diagnosed thyroid disorders are associated with depression and anxiety","volume":"50","author":"Ittermann","year":"2015","journal-title":"Soc. Psychiatry Psychiatr. Epidemiol."},{"key":"10.1016\/j.bbi.2020.07.039_b0145","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.biopsych.2017.06.015","article-title":"Cell- and single molecule-based methods to detect anti-N-Methyl-D-aspartate receptor autoantibodies in patients with first-episode psychosis from the OPTiMiSE project","volume":"82","author":"J\u00e9z\u00e9quel","year":"2017","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2020.07.039_b0150","doi-asserted-by":"crossref","first-page":"24","DOI":"10.12779\/dnd.2016.15.1.24","article-title":"Thyroid autoantibody positive anti-N-methyl-D-aspartate receptor encephalitis","volume":"15","author":"Jung","year":"2016","journal-title":"Dementia Neurocognitive Disorders"},{"key":"10.1016\/j.bbi.2020.07.039_b0155","doi-asserted-by":"crossref","first-page":"10","DOI":"10.4103\/trp.trp_42_17","article-title":"Depression, anxiety, and somatization in patients with clinical and subclinical hypothyroidism: an exploratory study","volume":"15","author":"Kale","year":"2018","journal-title":"Thyroid Res Pract"},{"key":"10.1016\/j.bbi.2020.07.039_b0160","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1111\/ane.12556","article-title":"Initial serum thyroid peroxidase antibodies and long-term outcomes in SREAT","volume":"134","author":"Litmeier","year":"2016","journal-title":"Acta Neurol. Scand."},{"key":"10.1016\/j.bbi.2020.07.039_b0165","unstructured":"Mincer, D.L., Jialal, I., 2020. Hashimoto Thyroiditis. StatPearls, Treasure Island (FL)."},{"key":"10.1016\/j.bbi.2020.07.039_b0170","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.schres.2014.06.025","article-title":"Absence of dopamine receptor serum autoantibodies in schizophrenia patients with an acute disease episode","volume":"158","author":"M\u00fcller","year":"2014","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.bbi.2020.07.039_b0175","doi-asserted-by":"crossref","DOI":"10.1186\/s12974-018-1067-y","article-title":"A clinical approach to new-onset psychosis associated with immune dysregulation: the concept of autoimmune psychosis","author":"Najjar","year":"2018","journal-title":"J. Neuroinflammation. im Druck"},{"key":"10.1016\/j.bbi.2020.07.039_b0180","first-page":"532","article-title":"Sedative\/hypnotic dependence: patient stabilization, tolerance testing, and withdrawal","volume":"20","author":"Perry","year":"1986","journal-title":"Drug Intell. Clin. Pharm."},{"key":"10.1016\/j.bbi.2020.07.039_b0185","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S2215-0366(19)30290-1","article-title":"Autoimmune psychosis: an international consensus on an approach to the diagnosis and management of psychosis of suspected autoimmune origin","volume":"7","author":"Pollak","year":"2020","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/j.bbi.2020.07.039_b0190","unstructured":"Romano, J., Kromrey, J.D., Coraggio, J., Skowronek, J., Devine, L., 2006. Appropriate statistics for ordinal level data: Should we really be using t-test and cohen\u2019s d for evaluating group differences on the NSSE and other surveys? Annual meeting of the Florida Association of Institutional Research, Arlington, Virginia, 1\u201351."},{"key":"10.1016\/j.bbi.2020.07.039_b0195","article-title":"The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10","volume":"59 Suppl 20","author":"Sheehan","year":"1998","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.bbi.2020.07.039_b0200","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.3389\/fimmu.2019.02349","article-title":"The impact of obesity on thyroid autoimmunity and dysfunction: a systematic review and meta-analysis","volume":"10","author":"Song","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbi.2020.07.039_b0205","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1080\/15622975.2018.1555376","article-title":"Autoimmune encephalitis with psychosis: warning signs, step-by-step diagnostics and treatment","volume":"21","author":"Steiner","year":"2020","journal-title":"World J. Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2020.07.039_b0210","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1001\/jamapsychiatry.2014.469","article-title":"Prevalence of N-methyl-D-aspartate receptor autoantibodies in the peripheral blood: healthy control samples revisited","volume":"71","author":"Steiner","year":"2014","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.bbi.2020.07.039_b0215","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1001\/2013.jamapsychiatry.86","article-title":"Increased prevalence of diverse N-methyl-D-aspartate glutamate receptor antibodies in patients with an initial diagnosis of schizophrenia: specific relevance of IgG NR1a antibodies for distinction from N-methyl-D-aspartate glutamate receptor encephalitis","volume":"70","author":"Steiner","year":"2013","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.bbi.2020.07.039_b0220","first-page":"471","article-title":"Autoantibody diagnostics in neurology using native and recombinant antigenic substrates","volume":"84","author":"Stoecker","year":"2013","journal-title":"Nervenarzt"},{"key":"10.1016\/j.bbi.2020.07.039_b0225","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1002\/ajmg.b.32652","article-title":"Genetic correlations among psychiatric and immune-related phenotypes based on genome-wide association data","volume":"177","author":"Tylee","year":"2018","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"key":"10.1016\/j.bbi.2020.07.039_b0230","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1111\/j.1600-0447.2012.01870.x","article-title":"Association between thyroid function, thyroid autoimmunity, and state and trait factors of depression","volume":"126","author":"van de Ven","year":"2012","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.bbi.2020.07.039_b0235","first-page":"666","article-title":"Autoantibody-mediated encephalitis","volume":"115","author":"Wandinger","year":"2018","journal-title":"Deutsches Arzteblatt Int."},{"key":"10.1016\/j.bbi.2020.07.039_b0240","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1002\/glia.23143","article-title":"An astroglial basis of major depressive disorder? an overview","volume":"65","author":"Wang","year":"2017","journal-title":"Glia"},{"key":"10.1016\/j.bbi.2020.07.039_b0245","doi-asserted-by":"crossref","first-page":"663","DOI":"10.4088\/JCP.v64n0607","article-title":"Chlorpromazine equivalent doses for the newer atypical antipsychotics","volume":"64","author":"Woods","year":"2003","journal-title":"J. Clin. Psychiatry"}],"container-title":["Brain, Behavior, and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088915912030146X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088915912030146X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T08:01:19Z","timestamp":1760169679000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S088915912030146X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":49,"alternative-id":["S088915912030146X"],"URL":"https:\/\/doi.org\/10.1016\/j.bbi.2020.07.039","relation":{},"ISSN":["0889-1591"],"issn-type":[{"type":"print","value":"0889-1591"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of thyroid peroxidase antibodies with anti-neuronal surface antibodies in health, depression and schizophrenia \u2013 Complementary linkage with somatic symptoms of major depression","name":"articletitle","label":"Article Title"},{"value":"Brain, Behavior, and Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbi.2020.07.039","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}