{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T18:29:15Z","timestamp":1793039355947,"version":"4.5.0"},"reference-count":81,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T00:00:00Z","timestamp":1710374400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100020872","name":"Tainan Municipal An-Nan Hospital-China Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020872","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020595","name":"National Science and Technology Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020595","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004391","name":"China Medical University Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004391","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012544","name":"China Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012544","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain, Behavior, and Immunity"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.bbi.2024.03.019","type":"journal-article","created":{"date-parts":[[2024,3,16]],"date-time":"2024-03-16T16:19:44Z","timestamp":1710605984000},"page":"459-467","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"special_numbering":"C","title":["A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine"],"prefix":"10.1016","volume":"118","author":[{"given":"Hsueh-Fang","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Chun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halliru","family":"Zailani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-Chia","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting-Bin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching-Mao","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I-Ju","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Pai","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuan-Pin","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbi.2024.03.019_b0005","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s00251-017-0992-8","article-title":"The synergistic effects of omega-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-alpha gene expression and serum level in migraine patients","volume":"69","author":"Abdolahi","year":"2017","journal-title":"Immunogenetics"},{"key":"10.1016\/j.bbi.2024.03.019_b0010","doi-asserted-by":"crossref","first-page":"430","DOI":"10.2174\/1871527317666180625101643","article-title":"A novel combination of omega-3 fatty acids and Nano-curcumin modulates Interleukin-6 gene expression and high sensitivity C-reactive protein serum levels in patients with migraine: a randomized clinical trial study","volume":"17","author":"Abdolahi","year":"2018","journal-title":"CNS Neurol. Disord. Drug Targets"},{"key":"10.1016\/j.bbi.2024.03.019_b0015","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1186\/s13104-021-05700-x","article-title":"The omega-3 and Nano-curcumin effects on vascular cell adhesion molecule (VCAM) in episodic migraine patients: a randomized clinical trial","volume":"14","author":"Abdolahi","year":"2021","journal-title":"BMC. Res. Notes"},{"key":"10.1016\/j.bbi.2024.03.019_b0020","doi-asserted-by":"crossref","unstructured":"Abu-Arafeh, I., Hershey, A.D., Diener, H.C., Tassorelli, C., Clinical Trials Standing, C., the, C., Adolescent Standing Committee of the International Headache, S., 2019. Guidelines of the International Headache Society for controlled trials of preventive treatment of migraine in children and adolescents, 1st edition. Cephalalgia 39, 803-816.","DOI":"10.1177\/0333102419842188"},{"key":"10.1016\/j.bbi.2024.03.019_b0025","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s10194-010-0282-4","article-title":"Migraine and psychiatric comorbidity: a review of clinical findings","volume":"12","author":"Antonaci","year":"2011","journal-title":"J. Headache Pain"},{"key":"10.1016\/j.bbi.2024.03.019_b0030","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1016\/S0140-6736(20)32160-7","article-title":"Migraine: epidemiology and systems of care","volume":"397","author":"Ashina","year":"2021","journal-title":"Lancet"},{"issue":"Suppl 1","key":"10.1016\/j.bbi.2024.03.019_b0035","doi-asserted-by":"crossref","first-page":"S61","DOI":"10.1007\/s10072-009-0071-5","article-title":"Migraine and psychiatric disorders: comorbidities, mechanisms, and clinical applications","volume":"30","author":"Baskin","year":"2009","journal-title":"Neurol. Sci."},{"key":"10.1016\/j.bbi.2024.03.019_b0040","doi-asserted-by":"crossref","first-page":"71i","DOI":"10.1016\/j.amjcard.2005.12.029","article-title":"Clinical overview of omacor: a concentrated formulation of omega-3 polyunsaturated fatty acids","volume":"98","author":"Bays","year":"2006","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.bbi.2024.03.019_b0045","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJMoa1812792","article-title":"Cardiovascular risk reduction with icosapent ethyl for Hypertriglyceridemia","volume":"380","author":"Bhatt","year":"2019","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.bbi.2024.03.019_b0050","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0165-1781(91)90102-U","article-title":"Migraine, psychiatric disorders, and suicide attempts: an epidemiologic study of young adults","volume":"37","author":"Breslau","year":"1991","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.bbi.2024.03.019_b0055","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1212\/WNL.54.2.308","article-title":"Headache and major depression: is the association specific to migraine?","volume":"54","author":"Breslau","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/j.bbi.2024.03.019_b0060","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.ncl.2019.06.001","article-title":"Migraine: epidemiology, burden, and comorbidity","volume":"37","author":"Burch","year":"2019","journal-title":"Neurol. Clin."},{"key":"10.1016\/j.bbi.2024.03.019_b0065","doi-asserted-by":"crossref","first-page":"1505S","DOI":"10.1093\/ajcn\/83.6.1505S","article-title":"n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases","volume":"83","author":"Calder","year":"2006","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.bbi.2024.03.019_b0070","doi-asserted-by":"crossref","first-page":"e22253","DOI":"10.1097\/MD.0000000000022253","article-title":"Clinical use of omega-3 fatty acids in migraine: a narrative review","volume":"99","author":"Cardia","year":"2020","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.bbi.2024.03.019_b0075","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/s12955-019-1169-y","article-title":"Migraine-specific quality of life questionnaire chinese version 2.1 (MSQv2.1-C): psychometric evaluation in patients with migraine","volume":"17","author":"Chang","year":"2019","journal-title":"Health Qual. Life Outcomes"},{"key":"10.1016\/j.bbi.2024.03.019_b0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.plefa.2018.01.001","article-title":"Safety and tolerability of prescription omega-3 fatty acids: a systematic review and meta-analysis of randomized controlled trials","volume":"129","author":"Chang","year":"2018","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.bbi.2024.03.019_b0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.advnut.2023.08.003","article-title":"Safety of supplementation of Omega-3 Polyunsaturated fatty acids: a systematic review and meta-analysis of randomized controlled trials","author":"Chang","year":"2023","journal-title":"Adv. Nutr."},{"key":"10.1016\/j.bbi.2024.03.019_b0090","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1007\/s40263-023-01037-0","article-title":"Network meta-analysis of different treatments for Vestibular migraine","volume":"37","author":"Chen","year":"2023","journal-title":"CNS Drugs"},{"issue":"44\u201346","key":"10.1016\/j.bbi.2024.03.019_b0095","first-page":"64","article-title":"Epidemiologic survey of migraine in six cities of China","volume":"23","author":"Cheng","year":"1990","journal-title":"Zhonghua Shen Jing Jing Shen Ke Za Zhi"},{"key":"10.1016\/j.bbi.2024.03.019_b0100","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s10194-022-01401-3","article-title":"Effectiveness and acceptability of noninvasive brain and nerve stimulation techniques for migraine prophylaxis: a network meta-analysis of randomized controlled trials","volume":"23","author":"Cheng","year":"2022","journal-title":"J. Headache Pain"},{"key":"10.1016\/j.bbi.2024.03.019_b0105","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s11883-004-0090-x","article-title":"Effects of omega-3 fatty acids on cytokines and adhesion molecules","volume":"6","author":"De Caterina","year":"2004","journal-title":"Curr. Atheroscler. Rep."},{"key":"10.1016\/j.bbi.2024.03.019_b0110","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jphs.2021.05.002","article-title":"Resolvins as potential candidates for the treatment of major depressive disorder","volume":"147","author":"Deyama","year":"2021","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.bbi.2024.03.019_b0115","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/S0140-6736(17)32154-2","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990\u20132016: a systematic analysis for the global burden of disease study 2016","volume":"390","author":"Disease","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.bbi.2024.03.019_b0120","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1080\/08923973.2023.2196600","article-title":"The effect of omega-3 fatty acids supplementation on inflammatory biomarkers in subjects with migraine: a randomized, double-blind, placebo-controlled trial","volume":"45","author":"Djalali","year":"2023","journal-title":"Immunopharmacol. Immunotoxicol."},{"key":"10.1016\/j.bbi.2024.03.019_b0125","doi-asserted-by":"crossref","first-page":"302","DOI":"10.3389\/fncel.2014.00302","article-title":"The role of the blood-brain barrier in the development and treatment of migraine and other pain disorders","volume":"8","author":"DosSantos","year":"2014","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.bbi.2024.03.019_b0130","first-page":"9","article-title":"Omega 3 in childhood migraines: a double blind randomized clinical trial","volume":"10","author":"Fayyazi","year":"2016","journal-title":"Iran J Child Neurol"},{"key":"10.1016\/j.bbi.2024.03.019_b0135","doi-asserted-by":"crossref","DOI":"10.3390\/nu12061658","article-title":"Migraine and diet","volume":"12","author":"Gazerani","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.bbi.2024.03.019_b0140","doi-asserted-by":"crossref","first-page":"122","DOI":"10.3389\/fpsyt.2020.00122","article-title":"The anti-inflammatory role of Omega-3 Polyunsaturated fatty acids metabolites in pre-clinical models of psychiatric, neurodegenerative, and neurological Disorders","volume":"11","author":"Giacobbe","year":"2020","journal-title":"Front. Psych."},{"key":"10.1016\/j.bbi.2024.03.019_b0145","first-page":"796A","article-title":"Amelioration of severe migraine with v3 fatty acids: a double-blind, placebo- controlled clinical trial","volume":"34","author":"Glueck","year":"1986","journal-title":"Clin. Res."},{"key":"10.1016\/j.bbi.2024.03.019_b0150","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.plefa.2007.10.004","article-title":"Regulation of adhesion molecule expression in human endothelial and smooth muscle cells by omega-3 fatty acids and conjugated linoleic acids: involvement of the transcription factor NF-kappaB?","volume":"78","author":"Goua","year":"2008","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.bbi.2024.03.019_b0155","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1159\/000502652","article-title":"International Society for Nutritional Psychiatry Research Practice Guidelines for Omega-3 fatty acids in the treatment of major depressive Disorder","volume":"88","author":"Guu","year":"2019","journal-title":"Psychother. Psychosom."},{"key":"10.1016\/j.bbi.2024.03.019_b0160","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/S1054-139X(02)00349-X","article-title":"Supplementation with omega-3 polyunsaturated fatty acids in the management of recurrent migraines in adolescents","volume":"31","author":"Harel","year":"2002","journal-title":"J. Adolesc. Health"},{"key":"10.1016\/j.bbi.2024.03.019_b0165","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.psychres.2017.02.056","article-title":"Altered soluble epoxide hydrolase-derived oxylipins in patients with seasonal major depression: an exploratory study","volume":"252","author":"Hennebelle","year":"2017","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.bbi.2024.03.019_b0170","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0929-6646(09)60151-0","article-title":"Validity, reliability and application of the taiwan version of the migraine disability assessment questionnaire","volume":"105","author":"Hung","year":"2006","journal-title":"J. Formos. Med. Assoc."},{"key":"10.1016\/j.bbi.2024.03.019_b0175","series-title":"The international classification of headache Disorders","author":"Ihs","year":"2018"},{"key":"10.1016\/j.bbi.2024.03.019_b0180","doi-asserted-by":"crossref","first-page":"707","DOI":"10.2165\/00019053-199813060-00007","article-title":"MSQ: migraine-specific quality-of-life questionnaire. further investigation of the factor structure","volume":"13","author":"Jhingran","year":"1998","journal-title":"Pharmacoeconomics"},{"key":"10.1016\/j.bbi.2024.03.019_b0185","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1007\/s11916-011-0233-z","article-title":"Defining the differences between episodic migraine and chronic migraine","volume":"16","author":"Katsarava","year":"2012","journal-title":"Curr. Pain Headache Rep."},{"key":"10.1016\/j.bbi.2024.03.019_b0190","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/s10194-021-01271-1","article-title":"Migraine and neuroinflammation: the inflammasome perspective","volume":"22","author":"Kursun","year":"2021","journal-title":"J. Headache Pain"},{"key":"10.1016\/j.bbi.2024.03.019_b0195","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s40265-019-01069-1","article-title":"Erenumab for preventive treatment of migraine: a systematic review and meta-analysis of efficacy and safety","volume":"79","author":"Lattanzi","year":"2019","journal-title":"Drugs"},{"key":"10.1016\/j.bbi.2024.03.019_b0200","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.plefa.2010.02.006","article-title":"Polyunsaturated fatty acids, neuroinflammation and well being","volume":"82","author":"Laye","year":"2010","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.bbi.2024.03.019_b0205","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.pnpbp.2017.04.006","article-title":"Antidepressants and risk of dementia in migraine patients: a population-based case-control study","volume":"77","author":"Lee","year":"2017","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2024.03.019_b0210","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1080\/1028415X.2020.1735143","article-title":"Potential treatment of Parkinson's disease with omega-3 polyunsaturated fatty acids","volume":"25","author":"Li","year":"2022","journal-title":"Nutr. Neurosci."},{"key":"10.1016\/j.bbi.2024.03.019_b0215","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.bbi.2020.06.033","article-title":"Transient receptor potential V1 (TRPV1) modulates the therapeutic effects for comorbidity of pain and depression: the common molecular implication for electroacupuncture and omega-3 polyunsaturated fatty acids","volume":"89","author":"Lin","year":"2020","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbi.2024.03.019_b0220","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1038\/mp.2012.111","article-title":"Are omega-3 fatty acids antidepressants or just mood-improving agents? the effect depends upon diagnosis, supplement preparation, and severity of depression","volume":"17","author":"Lin","year":"2012","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.bbi.2024.03.019_b0225","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.4088\/JCP.v68n0712","article-title":"A meta-analytic review of double-blind, placebo-controlled trials of antidepressant efficacy of omega-3 fatty acids","volume":"68","author":"Lin","year":"2007","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.bbi.2024.03.019_b0230","doi-asserted-by":"crossref","first-page":"5592","DOI":"10.1007\/s12035-023-03419-3","article-title":"Omega-3 Polyunsaturated fatty acids protect neurological function after traumatic brain injury by suppressing microglial transformation to the proinflammatory phenotype and activating exosomal NGF\/TrkA signaling","volume":"60","author":"Lin","year":"2023","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.bbi.2024.03.019_b0235","doi-asserted-by":"crossref","first-page":"233","DOI":"10.3389\/fncel.2018.00233","article-title":"Vascular contributions to migraine: time to revisit?","volume":"12","author":"Mason","year":"2018","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.bbi.2024.03.019_b0240","first-page":"275A","article-title":"Amelioration of severe migraine by\u00aeshoil(v3) fatty acids","volume":"33","author":"Mccarren","year":"1985","journal-title":"Clin. Res."},{"key":"10.1016\/j.bbi.2024.03.019_b0245","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1136\/jnnp-2015-312233","article-title":"Migraine and its psychiatric comorbidities","volume":"87","author":"Minen","year":"2016","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.bbi.2024.03.019_b0250","doi-asserted-by":"crossref","first-page":"S59","DOI":"10.4103\/0028-3886.315997","article-title":"Role of monoclonal antibodies against calcitonin gene-related peptide (CGRP) in Episodic migraine prevention: where do we stand today?","volume":"69","author":"Nagaraj","year":"2021","journal-title":"Neurol. India"},{"key":"10.1016\/j.bbi.2024.03.019_b0255","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ahj.2022.11.008","volume":"257","author":"Nishizaki","year":"2023","journal-title":"Am. Heart J."},{"issue":"Suppl","key":"10.1016\/j.bbi.2024.03.019_b0260","first-page":"1","article-title":"Migraine pathophysiology: anatomy of the trigeminovascular pathway and associated neurological symptoms, CSD, sensitization and modulation of pain","volume":"154","author":"Noseda","year":"2013","journal-title":"Pain"},{"key":"10.1016\/j.bbi.2024.03.019_b0265","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1046\/j.1468-2982.2001.218240.x","article-title":"Failure of omega-3 polyunsaturated fatty acids in prevention of migraine: a double-blind study versus placebo","volume":"21","author":"Pradalier","year":"2001","journal-title":"Cephalalgia"},{"key":"10.1016\/j.bbi.2024.03.019_b0270","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/j.1468-2982.2004.00839.x","article-title":"Psychiatric comorbidity in migraine: a review","volume":"25","author":"Radat","year":"2005","journal-title":"Cephalalgia"},{"key":"10.1016\/j.bbi.2024.03.019_b0275","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1016\/j.pain.2013.07.028","article-title":"Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: a randomized trial","volume":"154","author":"Ramsden","year":"2013","journal-title":"Pain"},{"key":"10.1016\/j.bbi.2024.03.019_b0280","article-title":"Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial","volume":"374","author":"Ramsden","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.bbi.2024.03.019_b0285","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1212\/WNL.0b013e31826170ce","article-title":"Endothelial progenitor cells: a new key for endothelial dysfunction in migraine","volume":"79","author":"Rodriguez-Osorio","year":"2012","journal-title":"Neurology"},{"key":"10.1016\/j.bbi.2024.03.019_b0290","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1111\/bcp.12686","article-title":"CGRP as a neuropeptide in migraine: lessons from mice","volume":"80","author":"Russo","year":"2015","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.bbi.2024.03.019_b0295","doi-asserted-by":"crossref","first-page":"334","DOI":"10.4103\/1735-9066.157831","article-title":"The relationship between different fatty acids intake and frequency of migraine attacks","volume":"20","author":"Sadeghi","year":"2015","journal-title":"Iran. J. Nurs. Midwifery Res."},{"key":"10.1016\/j.bbi.2024.03.019_b0300","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1046\/j.1468-2982.1997.1701015.x","article-title":"Prevalence of migraine in Japan: a nationwide survey","volume":"17","author":"Sakai","year":"1997","journal-title":"Cephalalgia"},{"key":"10.1016\/j.bbi.2024.03.019_b0305","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.bbi.2019.08.190","article-title":"miR-200a-3p modulates gene expression in comorbid pain and depression: Molecular implication for central sensitization","volume":"82","author":"Satyanarayanan","year":"2019","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbi.2024.03.019_b0310","article-title":"CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials","volume":"340","author":"Schulz, K.F., Altman, D.G., Moher, D., Group, C.","year":"2010","journal-title":"BMJ"},{"key":"10.1016\/j.bbi.2024.03.019_b0315","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1590\/0004-282x-anp-2022-s125","article-title":"Why are CGRP monoclonal antibodies not yet the first line treatment in migraine prevention?","volume":"80","author":"Simioni","year":"2022","journal-title":"Arq. Neuropsiquiatr."},{"key":"10.1016\/j.bbi.2024.03.019_b0320","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1080\/1028415X.2016.1266133","article-title":"A double- blind, randomized, and placebo-controlled clinical trial with omega-3 polyunsaturated fatty acids (OPFA -3) for the prevention of migraine in chronic migraine patients using amitriptyline","volume":"21","author":"Soares","year":"2018","journal-title":"Nutr. Neurosci."},{"key":"10.1016\/j.bbi.2024.03.019_b0325","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1080\/1028415X.2016.1266133","article-title":"A double- blind, randomized, and placebo-controlled clinical trial with omega-3 polyunsaturated fatty acids (OPFA \u0277-3) for the prevention of migraine in chronic migraine patients using amitriptyline","volume":"21","author":"Soares","year":"2018","journal-title":"Nutr. Neurosci."},{"key":"10.1016\/j.bbi.2024.03.019_b0330","doi-asserted-by":"crossref","unstructured":"Stewart, W.F., Lipton, R.B., Kolodner, K., Liberman, J., Sawyer, J., 1999. Reliability of the migraine disability assessment score in a population-based sample of headache sufferers. Cephalalgia 19, 107-114; discussion 174.","DOI":"10.1046\/j.1468-2982.1999.019002107.x"},{"key":"10.1016\/j.bbi.2024.03.019_b0335","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1159\/000198167","article-title":"Biological mechanism of antidepressant effect of omega-3 fatty acids: how does fish oil act as a 'mind-body interface'?","volume":"17","author":"Su","year":"2009","journal-title":"Neurosignals"},{"key":"10.1016\/j.bbi.2024.03.019_b0340","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.biopsych.2014.01.008","article-title":"Omega-3 fatty acids in the prevention of interferon-alpha-induced depression: results from a randomized, controlled trial","volume":"76","author":"Su","year":"2014","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2024.03.019_b0345","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.pnpbp.2017.06.020","article-title":"Eicosapentaenoic and docosahexaenoic acids have different effects on peripheral phospholipase A2 gene expressions in acute depressed patients","volume":"80","author":"Su","year":"2018","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2024.03.019_b0350","first-page":"21","article-title":"The effects of sodium valproate with fish oil supplementation or alone in migraine prevention: a randomized single-blind clinical trial","volume":"11","author":"Tajmirriahi","year":"2012","journal-title":"Iran J Neurol"},{"key":"10.1016\/j.bbi.2024.03.019_b0355","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1177\/0333102419877663","article-title":"Problematic presentation and use of efficacy measures in current trials of CGRP monoclonal antibodies for episodic migraine prevention: a mini-review","volume":"40","author":"Tfelt-Hansen","year":"2020","journal-title":"Cephalalgia"},{"key":"10.1016\/j.bbi.2024.03.019_b0360","doi-asserted-by":"crossref","first-page":"e12663","DOI":"10.1111\/jpi.12663","article-title":"The association between melatonin and episodic migraine: a pilot network meta-analysis of randomized controlled trials to compare the prophylactic effects with exogenous melatonin supplementation and pharmacotherapy","volume":"69","author":"Tseng","year":"2020","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.bbi.2024.03.019_b0365","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.bbi.2023.04.017","article-title":"Efficacy and acceptability of anti-inflammatory eicosapentaenoic acid for cognitive function in Alzheimer's dementia: a network meta-analysis of randomized, placebo-controlled trials with omega-3 fatty acids and FDA-approved pharmacotherapy","volume":"111","author":"Tseng","year":"2023","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbi.2024.03.019_b0370","doi-asserted-by":"crossref","DOI":"10.3390\/jpm10040283","article-title":"Brain responses to emotional stimuli after eicosapentaenoic acid and Docosahexaenoic acid treatments in major depressive Disorder: Toward personalized medicine with anti-inflammatory Nutraceuticals","volume":"10","author":"Tu","year":"2020","journal-title":"J Pers Med"},{"key":"10.1016\/j.bbi.2024.03.019_b0375","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1159\/000109782","article-title":"Prevalence of migraine and other headaches in Hong Kong","volume":"14","author":"Wong","year":"1995","journal-title":"Neuroepidemiology"},{"key":"10.1016\/j.bbi.2024.03.019_b0380","doi-asserted-by":"crossref","unstructured":"Xu, Z.Z., Zhang, L., Liu, T., Park, J.Y., Berta, T., Yang, R., Serhan, C.N., Ji, R.R., 2010. Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions. Nat Med 16, 592-597, 591p following 597.","DOI":"10.1038\/nm.2123"},{"key":"10.1016\/j.bbi.2024.03.019_b0385","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/S0140-6736(07)60527-3","article-title":"Japan, e.p.a.l.i.s.i., effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis","volume":"369","author":"Yokoyama","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.bbi.2024.03.019_b0390","doi-asserted-by":"crossref","DOI":"10.3390\/nu15204363","article-title":"Roles of Omega-3 Polyunsaturated fatty acids in managing cognitive impairment in chronic obstructive Pulmonary disease: a review","volume":"15","author":"Zailani","year":"2023","journal-title":"Nutrients"},{"key":"10.1016\/j.bbi.2024.03.019_b0395","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1111\/j.1526-4610.1988.hed2808558.x","article-title":"Epidemiology of migraine: a survey in 21 provinces of the People's Republic of China, 1985","volume":"28","author":"Zhao","year":"1988","journal-title":"Headache"},{"key":"10.1016\/j.bbi.2024.03.019_b0400","article-title":"Possible antidepressant mechanisms of omega-3 polyunsaturated fatty acids acting on the central nervous system","volume":"13","author":"Zhou","year":"2022","journal-title":"Front. Psych."},{"key":"10.1016\/j.bbi.2024.03.019_b0405","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","article-title":"The hospital anxiety and depression scale","volume":"67","author":"Zigmond","year":"1983","journal-title":"Acta Psychiatr. Scand."}],"container-title":["Brain, Behavior, and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159124003003?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159124003003?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T03:08:47Z","timestamp":1742180927000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889159124003003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":81,"alternative-id":["S0889159124003003"],"URL":"https:\/\/doi.org\/10.1016\/j.bbi.2024.03.019","relation":{},"ISSN":["0889-1591"],"issn-type":[{"value":"0889-1591","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine","name":"articletitle","label":"Article Title"},{"value":"Brain, Behavior, and Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbi.2024.03.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}