{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T20:27:27Z","timestamp":1793219247419,"version":"4.5.0"},"reference-count":64,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T00:00:00Z","timestamp":1718582400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain, Behavior, and Immunity"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.bbi.2024.06.017","type":"journal-article","created":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T19:33:45Z","timestamp":1718825625000},"page":"379-390","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Exercise4Psychosis: A randomised control trial assessing the effect of moderate-to-vigorous exercise on inflammatory biomarkers and negative symptom profiles in men with first-episode psychosis"],"prefix":"10.1016","volume":"120","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2340-9012","authenticated-orcid":false,"given":"Connor","family":"Dunleavy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard J.","family":"Elsworthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.","family":"Wood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Allott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felicity","family":"Spencer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Upthegrove","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Aldred","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.bbi.2024.06.017_b0005","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1006\/cyto.1996.0178","article-title":"Cyclic plasma IL-6 levels during normal menstrual cycle","volume":"9","author":"Angstwurm","year":"1997","journal-title":"Cytokine"},{"issue":"8","key":"10.1016\/j.bbi.2024.06.017_b0010","doi-asserted-by":"crossref","first-page":"973","DOI":"10.2174\/1381612053381684","article-title":"Blood-brain barrier transport of cytokines: a mechanism for neuropathology","volume":"11","author":"Banks","year":"2005","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.bbi.2024.06.017_b0015","doi-asserted-by":"crossref","first-page":"1175171","DOI":"10.3389\/fpsyt.2023.1175171","article-title":"Alterations in inflammatory markers after a 12-week exercise program in individuals with schizophrenia\u2014a randomized controlled trial","volume":"14","author":"Bigseth","year":"2023","journal-title":"Front. Psych."},{"issue":"1","key":"10.1016\/j.bbi.2024.06.017_b0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2288-13-104","article-title":"An audit of sample sizes for pilot and feasibility trials being undertaken in the United Kingdom registered in the United Kingdom Clinical Research Network database","volume":"13","author":"Billingham","year":"2013","journal-title":"BMC Med. Res. Method."},{"key":"10.1016\/j.bbi.2024.06.017_b0025","doi-asserted-by":"crossref","first-page":"274","DOI":"10.3389\/fncel.2020.00274","article-title":"The Inflamed Brain in Schizophrenia: The Convergence of Genetic and Environmental Risk Factors That Lead to Uncontrolled Neuroinflammation","volume":"14","author":"Comer","year":"2020","journal-title":"Front. Cell. Neurosci."},{"issue":"9","key":"10.1016\/j.bbi.2024.06.017_b0030","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.tins.2007.06.011","article-title":"Exercise builds brain health: key roles of growth factor cascades and inflammation","volume":"30","author":"Cotman","year":"2007","journal-title":"Trends Neurosci."},{"issue":"10","key":"10.1016\/j.bbi.2024.06.017_b0035","doi-asserted-by":"crossref","first-page":"6460","DOI":"10.1007\/s12035-022-02976-3","article-title":"Linking inflammation, aberrant glutamate-dopamine interaction, and post-synaptic changes: translational relevance for schizophrenia and antipsychotic treatment: a systematic review","volume":"59","author":"de Bartolomeis","year":"2022","journal-title":"Mol. Neurobiol."},{"issue":"1","key":"10.1016\/j.bbi.2024.06.017_b0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13102-022-00397-2","article-title":"The effect of exercise on cytokines: implications for musculoskeletal health: a narrative review","volume":"14","author":"Docherty","year":"2022","journal-title":"BMC Sports Sci. Med. Rehabil."},{"issue":"6","key":"10.1016\/j.bbi.2024.06.017_b0045","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1017\/S1461145710001653","article-title":"An activated set point of T-cell and monocyte inflammatory networks in recent-onset schizophrenia patients involves both pro-and anti-inflammatory forces","volume":"14","author":"Drexhage","year":"2011","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.bbi.2024.06.017_b0050","doi-asserted-by":"crossref","DOI":"10.1111\/acps.13416","article-title":"Inflammation in First-Episode Psychosis: The Contribution of Inflammatory Biomarkers to the Emergence of Negative Symptoms, A Systematic Review and Meta-Analysis","author":"Dunleavy","year":"2022","journal-title":"Acta Psychiatr. Scand."},{"issue":"5","key":"10.1016\/j.bbi.2024.06.017_b0055","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1093\/schbul\/sbl071","article-title":"Psychiatric symptoms and quality of life in schizophrenia: a meta-analysis","volume":"33","author":"Eack","year":"2007","journal-title":"Schizophr. Bull."},{"issue":"11","key":"10.1016\/j.bbi.2024.06.017_b0060","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1017\/S0033291706008774","article-title":"Incidence of schizophrenia and other psychoses in ethnic minority groups: results from the MRC AESOP Study","volume":"36","author":"Fearon","year":"2006","journal-title":"Psychol. Med."},{"issue":"11","key":"10.1016\/j.bbi.2024.06.017_b0065","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1096\/fj.01-0876rev","article-title":"Muscle-derived interleukin-6: mechanisms for activation and possible biological roles","volume":"16","author":"Febbraio","year":"2002","journal-title":"FASEB J."},{"issue":"7","key":"10.1016\/j.bbi.2024.06.017_b0070","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1017\/S0033291714003110","article-title":"A systematic review and meta-analysis of exercise interventions in schizophrenia patients","volume":"45","author":"Firth","year":"2015","journal-title":"Psychol. Med."},{"issue":"1","key":"10.1016\/j.bbi.2024.06.017_b0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12888-016-0751-7","article-title":"The effects and determinants of exercise participation in first-episode psychosis: a qualitative study","volume":"16","author":"Firth","year":"2016","journal-title":"BMC Psychiatry"},{"issue":"3","key":"10.1016\/j.bbi.2024.06.017_b0080","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1111\/eip.12329","article-title":"Exercise as an intervention for first-episode psychosis: a feasibility study","volume":"12","author":"Firth","year":"2018","journal-title":"Early Interv. Psychiatry"},{"key":"10.1016\/j.bbi.2024.06.017_b0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2020.112840","article-title":"Designing a feasible exercise intervention in first-episode psychosis: exercise quality, engagement and effect","volume":"286","author":"Fisher","year":"2020","journal-title":"Psychiatry Res."},{"issue":"1","key":"10.1016\/j.bbi.2024.06.017_b0090","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41398-020-00927-x","article-title":"Exercise as a protective mechanism against the negative effects of oxidative stress in first-episode psychosis: a biomarker-led study","volume":"10","author":"Fisher","year":"2020","journal-title":"Transl. Psychiatry"},{"issue":"3","key":"10.1016\/j.bbi.2024.06.017_b0095","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1177\/1559827607300283","article-title":"State of the art reviews: The anti-inflammatory actions of exercise training","volume":"1","author":"Flynn","year":"2007","journal-title":"Am. J. Lifestyle Med."},{"issue":"3","key":"10.1016\/j.bbi.2024.06.017_b0100","doi-asserted-by":"crossref","first-page":"e067944","DOI":"10.1136\/bmjopen-2022-067944","article-title":"Protocol for the Psychosis Immune Mechanism Stratified Medicine (PIMS) trial: a randomised double-blind placebo-controlled trial of single-dose tocilizumab in patients with psychosis","volume":"13","author":"Foley","year":"2023","journal-title":"BMJ Open"},{"issue":"5","key":"10.1016\/j.bbi.2024.06.017_b0105","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.euroneuro.2013.10.017","article-title":"Negative symptoms of schizophrenia: clinical features, relevance to real world functioning and specificity versus other CNS disorders","volume":"24","author":"Foussias","year":"2014","journal-title":"Eur. Neuropsychopharmacol."},{"issue":"4","key":"10.1016\/j.bbi.2024.06.017_b0110","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1093\/schbul\/sby125","article-title":"Oxidative stress and inflammation in first-episode psychosis: a systematic review and meta-analysis","volume":"45","author":"Fraguas","year":"2019","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.bbi.2024.06.017_b0115","doi-asserted-by":"crossref","unstructured":"Garber CE, Blissmer B, Deschenes MR, Franklin BA, Lamonte MJ, Lee I-M, et al. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. 2011.","DOI":"10.1249\/MSS.0b013e318213fefb"},{"issue":"2","key":"10.1016\/j.bbi.2024.06.017_b0120","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.psychres.2011.08.014","article-title":"Inflammatory markers in antipsychotic-na\u00efve patients with nonaffective psychosis and deficit vs. nondeficit features","volume":"198","author":"Garcia-Rizo","year":"2012","journal-title":"Psychiatry Res."},{"issue":"6","key":"10.1016\/j.bbi.2024.06.017_b0125","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1016\/j.jrp.2005.11.001","article-title":"Anticipatory and consummatory components of the experience of pleasure: a scale development study","volume":"40","author":"Gard","year":"2006","journal-title":"J. Res. Pers."},{"issue":"9","key":"10.1016\/j.bbi.2024.06.017_b0130","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1038\/nri3041","article-title":"The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease","volume":"11","author":"Gleeson","year":"2011","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bbi.2024.06.017_b0135","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.bbi.2018.11.315","article-title":"Association of baseline inflammatory markers and the development of negative symptoms in individuals at clinical high risk for psychosis","volume":"76","author":"Goldsmith","year":"2019","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbi.2024.06.017_b0140","doi-asserted-by":"crossref","first-page":"46","DOI":"10.3389\/fpsyt.2020.00046","article-title":"Inflammation and negative symptoms of schizophrenia: implications for reward processing and motivational deficits","volume":"11","author":"Goldsmith","year":"2020","journal-title":"Front. Psych."},{"key":"10.1016\/j.bbi.2024.06.017_b0145","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.schres.2018.02.048","article-title":"TNF-\u03b1 and IL-6 are associated with the deficit syndrome and negative symptoms in patients with chronic schizophrenia","volume":"199","author":"Goldsmith","year":"2018","journal-title":"Schizophr. Res."},{"issue":"23","key":"10.1016\/j.bbi.2024.06.017_b0150","doi-asserted-by":"crossref","first-page":"5163","DOI":"10.1113\/JP281356","article-title":"Interpreting \u2018anti-inflammatory\u2019cytokine responses to exercise: focus on interleukin-10","volume":"599","author":"Islam","year":"2021","journal-title":"J. Physiol."},{"key":"10.1016\/j.bbi.2024.06.017_b0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2019.107704","article-title":"Antipsychotics: mechanisms underlying clinical response and side-effects and novel treatment approaches based on pathophysiology","volume":"172","author":"Kaar","year":"2020","journal-title":"Neuropharmacology"},{"issue":"5","key":"10.1016\/j.bbi.2024.06.017_b0160","doi-asserted-by":"crossref","first-page":"303","DOI":"10.2165\/00007256-198805050-00002","article-title":"Heart rate and exercise intensity during sports activities","volume":"5","author":"Karvonen","year":"1988","journal-title":"Sports Med."},{"issue":"2","key":"10.1016\/j.bbi.2024.06.017_b0165","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/schbul\/13.2.261","article-title":"The positive and negative syndrome scale (PANSS) for schizophrenia","volume":"13","author":"Kay","year":"1987","journal-title":"Schizophr. Bull."},{"issue":"4","key":"10.1016\/j.bbi.2024.06.017_b0170","doi-asserted-by":"crossref","first-page":"3719","DOI":"10.3390\/ijerph20043719","article-title":"Effects of Exercise on Positive Symptoms, Negative Symptoms, and Depression in Patients with Schizophrenia: A Systematic Review and Meta-Analysis","volume":"20","author":"Kim","year":"2023","journal-title":"Int. J. Environ. Res. Public Health"},{"issue":"7","key":"10.1016\/j.bbi.2024.06.017_b0175","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/j.pnpbp.2004.05.047","article-title":"Th1, Th2 and Th3 cytokine alteration in schizophrenia","volume":"28","author":"Kim","year":"2004","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"issue":"3","key":"10.1016\/j.bbi.2024.06.017_b0180","doi-asserted-by":"crossref","first-page":"e31660","DOI":"10.1371\/journal.pone.0031660","article-title":"Incidence of schizophrenia and other psychoses in England, 1950\u20132009: a systematic review and meta-analyses","volume":"7","author":"Kirkbride","year":"2012","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.bbi.2024.06.017_b0185","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1006\/brbi.1999.0570","article-title":"Modulation of IL-6 production during the menstrual cycle in vivo and in vitro","volume":"14","author":"Konecna","year":"2000","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbi.2024.06.017_b0190","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.physbeh.2016.10.021","article-title":"Exercise-induced modulation of histone H4 acetylation status and cytokines levels in patients with schizophrenia","volume":"168","author":"Lavratti","year":"2017","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.bbi.2024.06.017_b0195","doi-asserted-by":"crossref","unstructured":"McComb S, Thiriot A, Akache B, Krishnan L, Stark F. Introduction to the immune system. Immunoproteomics: Methods and Protocols. 2019:1-24.","DOI":"10.1007\/978-1-4939-9597-4_1"},{"issue":"S7","key":"10.1016\/j.bbi.2024.06.017_b0200","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.5694\/j.1326-5377.2007.tb01326.x","article-title":"Investing in youth mental health is a best buy","volume":"187","author":"McGorry","year":"2007","journal-title":"Med. J. Aust."},{"issue":"4","key":"10.1016\/j.bbi.2024.06.017_b0205","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1046\/j.1440-1614.2003.01192.x","article-title":"Early intervention in psychosis: an overdue reform","volume":"37","author":"McGorry","year":"2003","journal-title":"Aust. N. Z. J. Psychiatry"},{"key":"10.1016\/j.bbi.2024.06.017_b0210","series-title":"Guidelines for graded exercise testing and exercise prescription","author":"Medicine ACoS","year":"1980"},{"key":"10.1016\/j.bbi.2024.06.017_b0215","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.maturitas.2017.09.003","article-title":"Exercise and mental health","volume":"106","author":"Mikkelsen","year":"2017","journal-title":"Maturitas"},{"issue":"7","key":"10.1016\/j.bbi.2024.06.017_b0220","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.biopsych.2011.04.013","article-title":"Meta-analysis of cytokine alterations in schizophrenia: clinical status and antipsychotic effects","volume":"70","author":"Miller","year":"2011","journal-title":"Biol. Psychiatry"},{"issue":"10","key":"10.1016\/j.bbi.2024.06.017_b0225","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1016\/j.biopsych.2012.09.007","article-title":"Meta-analysis of lymphocytes in schizophrenia: clinical status and antipsychotic effects","volume":"73","author":"Miller","year":"2013","journal-title":"Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.bbi.2024.06.017_b0230","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1038\/nri.2015.5","article-title":"The role of inflammation in depression: from evolutionary imperative to modern treatment target","volume":"16","author":"Miller","year":"2016","journal-title":"Nat. Rev. Immunol."},{"issue":"1","key":"10.1016\/j.bbi.2024.06.017_b0235","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.ijsu.2011.10.001","article-title":"CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials","volume":"10","author":"Moher","year":"2012","journal-title":"Int. J. Surg."},{"issue":"5","key":"10.1016\/j.bbi.2024.06.017_b0240","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1093\/schbul\/sby024","article-title":"Inflammation in schizophrenia: pathogenetic aspects and therapeutic considerations","volume":"44","author":"M\u00fcller","year":"2018","journal-title":"Schizophr. Bull."},{"issue":"3","key":"10.1016\/j.bbi.2024.06.017_b0245","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.euroneuro.2018.12.008","article-title":"Activation of the immune-inflammatory response system and the compensatory immune-regulatory system in antipsychotic naive first episode psychosis","volume":"29","author":"Noto","year":"2019","journal-title":"Eur. Neuropsychopharmacol."},{"issue":"2","key":"10.1016\/j.bbi.2024.06.017_b0250","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1159\/000107423","article-title":"Impact of gender and menstrual cycle phase on plasma cytokine concentrations","volume":"14","author":"O\u2019Brien","year":"2007","journal-title":"Neuroimmunomodulation"},{"issue":"6","key":"10.1016\/j.bbi.2024.06.017_b0255","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1038\/s41380-018-0220-4","article-title":"Cerebrospinal fluid markers of inflammation and infections in schizophrenia and affective disorders: a systematic review and meta-analysis","volume":"24","author":"Orlovska-Waast","year":"2019","journal-title":"Mol. Psychiatry"},{"issue":"4","key":"10.1016\/j.bbi.2024.06.017_b0260","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1152\/physrev.90100.2007","article-title":"Muscle as an endocrine organ: focus on muscle-derived interleukin-6","volume":"88","author":"Pedersen","year":"2008","journal-title":"Physiol. Rev."},{"issue":"4","key":"10.1016\/j.bbi.2024.06.017_b0265","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1152\/japplphysiol.00164.2004","article-title":"The anti-inflammatory effect of exercise","volume":"98","author":"Petersen","year":"2005","journal-title":"J. Appl. Physiol."},{"issue":"4","key":"10.1016\/j.bbi.2024.06.017_b0270","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1152\/japplphysiol.00164.2004","article-title":"The anti-inflammatory effect of exercise","volume":"98","author":"Petersen","year":"2005","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.bbi.2024.06.017_b0275","unstructured":"Riebe D, Ehrman JK, Liguori G, Magal M, Medicine ACoS. ACSM's guidelines for exercise testing and prescription: Wolters Kluwer; 2018."},{"key":"10.1016\/j.bbi.2024.06.017_b0280","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1007\/s12035-019-01737-z","article-title":"The role of aberrations in the immune-inflammatory response system (IRS) and the compensatory immune-regulatory reflex system (CIRS) in different phenotypes of schizophrenia: the IRS-CIRS theory of schizophrenia","volume":"57","author":"Roomruangwong","year":"2020","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.bbi.2024.06.017_b0285","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.genhosppsych.2019.11.002","article-title":"Physical exercise for negative symptoms of schizophrenia: Systematic review of randomized controlled trials and meta-analysis","volume":"62","author":"Sabe","year":"2020","journal-title":"Gen. Hosp. Psychiatry"},{"key":"10.1016\/j.bbi.2024.06.017_b0290","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.cyto.2017.10.001","article-title":"T-cells and their cytokine production: The anti-inflammatory and immunosuppressive effects of strenuous exercise","volume":"104","author":"Shaw","year":"2018","journal-title":"Cytokine"},{"issue":"4","key":"10.1016\/j.bbi.2024.06.017_b0295","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1093\/schbul\/sbn167","article-title":"Periods of recovery in deficit syndrome schizophrenia: A 20-year multi\u2013follow-up longitudinal study","volume":"36","author":"Strauss","year":"2010","journal-title":"Schizophr. Bull."},{"issue":"1","key":"10.1016\/j.bbi.2024.06.017_b0300","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0735-1097(00)01054-8","article-title":"Age-predicted maximal heart rate revisited","volume":"37","author":"Tanaka","year":"2001","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.bbi.2024.06.017_b0305","first-page":"49","article-title":"Cytokines, oxidative stress and cellular markers of inflammation in schizophrenia","author":"Upthegrove","year":"2020","journal-title":"Neuroinflammat. Schizophrenia."},{"issue":"1\u20133","key":"10.1016\/j.bbi.2024.06.017_b0310","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.schres.2014.03.005","article-title":"Cytokine function in medication-naive first episode psychosis: a systematic review and meta-analysis","volume":"155","author":"Upthegrove","year":"2014","journal-title":"Schizophr. Res."},{"issue":"1","key":"10.1016\/j.bbi.2024.06.017_b0315","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1111\/eip.12946","article-title":"Changes in inflammation are related to depression and amount of aerobic exercise in first episode schizophrenia","volume":"15","author":"Ventura","year":"2021","journal-title":"Early Interv. Psychiatry"},{"key":"10.1016\/j.bbi.2024.06.017_b0320","doi-asserted-by":"crossref","DOI":"10.1001\/jamapsychiatry.2022.0407","article-title":"Inflammation and Brain Structure in Schizophrenia and Other Neuropsychiatric Disorders: A Mendelian Randomization Study","author":"Williams","year":"2022","journal-title":"JAMA Psychiat."}],"container-title":["Brain, Behavior, and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159124004574?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159124004574?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T15:10:50Z","timestamp":1721661050000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889159124004574"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":64,"alternative-id":["S0889159124004574"],"URL":"https:\/\/doi.org\/10.1016\/j.bbi.2024.06.017","relation":{},"ISSN":["0889-1591"],"issn-type":[{"value":"0889-1591","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exercise4Psychosis: A randomised control trial assessing the effect of moderate-to-vigorous exercise on inflammatory biomarkers and negative symptom profiles in men with first-episode psychosis","name":"articletitle","label":"Article Title"},{"value":"Brain, Behavior, and Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbi.2024.06.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}