{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T18:06:46Z","timestamp":1791828406601,"version":"4.3.4"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T00:00:00Z","timestamp":1758326400000},"content-version":"am","delay-in-days":262,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["R01NS121103"],"award-info":[{"award-number":["R01NS121103"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["R01NS119540"],"award-info":[{"award-number":["R01NS119540"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain, Behavior, and Immunity"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.bbi.2024.09.023","type":"journal-article","created":{"date-parts":[[2024,9,17]],"date-time":"2024-09-17T19:44:08Z","timestamp":1726602248000},"page":"244-253","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["Skull bone marrow-derived immune cells infiltrate the injured cerebral cortex and exhibit anti-inflammatory properties"],"prefix":"10.1016","volume":"123","author":[{"given":"Eman","family":"Soliman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erwin Kristobal","family":"Gudenschwager Basso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Ju","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Willison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6485-2104","authenticated-orcid":false,"given":"Michelle H.","family":"Theus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.bbi.2024.09.023_b0005","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1186\/s12974-020-02005-x","article-title":"Cellular infiltration in traumatic brain injury","volume":"17","author":"Alam","year":"2020","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.bbi.2024.09.023_b0010","doi-asserted-by":"crossref","first-page":"6373506","DOI":"10.1155\/2016\/6373506","article-title":"Nonessential role for the NLRP1 inflammasome complex in a murine model of traumatic brain injury","volume":"2016","author":"Brickler","year":"2016","journal-title":"Mediators Inflamm."},{"issue":"45","key":"10.1016\/j.bbi.2024.09.023_b0015","doi-asserted-by":"crossref","first-page":"9618","DOI":"10.1523\/JNEUROSCI.0914-18.2018","article-title":"Angiopoietin\/Tie2 axis regulates the age-at-injury cerebrovascular response to traumatic brain injury","volume":"38","author":"Brickler","year":"2018","journal-title":"J. Neurosci."},{"issue":"41","key":"10.1016\/j.bbi.2024.09.023_b0020","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2204700120","article-title":"Endothelial deletion of EPH receptor A4 alters single-cell profile and Tie2\/Akap12 signaling to preserve blood-brain barrier integrity","volume":"120","author":"Cash","year":"2023","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"1","key":"10.1016\/j.bbi.2024.09.023_b0025","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1186\/s12974-016-0738-9","article-title":"Neurogenic inflammation after traumatic brain injury and its potentiation of classical inflammation","volume":"13","author":"Corrigan","year":"2016","journal-title":"J. Neuroinflammation"},{"issue":"6553","key":"10.1016\/j.bbi.2024.09.023_b0030","doi-asserted-by":"crossref","DOI":"10.1126\/science.abf7844","article-title":"Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma","volume":"373","author":"Cugurra","year":"2021","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.bbi.2024.09.023_b0035","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1007\/s12975-010-0044-2","article-title":"A protocol for characterizing the impact of collateral flow after distal middle cerebral artery occlusion","volume":"2","author":"Defazio","year":"2011","journal-title":"Transl. Stroke Res."},{"key":"10.1016\/j.bbi.2024.09.023_b0040","doi-asserted-by":"crossref","first-page":"1353513","DOI":"10.3389\/fimmu.2024.1353513","article-title":"The emerging importance of skull-brain interactions in traumatic brain injury","volume":"15","author":"Goodman","year":"2024","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.bbi.2024.09.023_b0045","doi-asserted-by":"crossref","first-page":"8564","DOI":"10.1038\/s41598-019-45089-z","article-title":"Divergent age-dependent peripheral immune transcriptomic profile following traumatic brain injury","volume":"9","author":"Hazy","year":"2019","journal-title":"Sci. Rep."},{"issue":"9","key":"10.1016\/j.bbi.2024.09.023_b0050","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1038\/s41593-018-0213-2","article-title":"Direct vascular channels connect skull bone marrow and the brain surface enabling myeloid cell migration","volume":"21","author":"Herisson","year":"2018","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbi.2024.09.023_b0055","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/978-1-62703-496-8_24","article-title":"Generation of bone marrow and fetal liver chimeric mice","volume":"1032","author":"Holl","year":"2013","journal-title":"Methods Mol. Biol."},{"issue":"1","key":"10.1016\/j.bbi.2024.09.023_b0060","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1186\/s12974-019-1605-2","article-title":"Peripheral loss of EphA4 ameliorates TBI-induced neuroinflammation and tissue damage","volume":"16","author":"Kowalski","year":"2019","journal-title":"J. Neuroinflammation"},{"issue":"15","key":"10.1016\/j.bbi.2024.09.023_b0065","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.156319","article-title":"Monocyte proinflammatory phenotypic control by ephrin type A receptor 4 mediates neural tissue damage","volume":"7","author":"Kowalski","year":"2022","journal-title":"JCI Insight"},{"issue":"8","key":"10.1016\/j.bbi.2024.09.023_b0070","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/j.bbi.2012.06.008","article-title":"Neuroinflammation after traumatic brain injury: opportunities for therapeutic intervention","volume":"26","author":"Kumar","year":"2012","journal-title":"Brain Behav. Immun."},{"issue":"5","key":"10.1016\/j.bbi.2024.09.023_b0075","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1038\/s41593-022-01029-1","article-title":"Cerebrospinal fluid regulates skull bone marrow niches via direct access through dural channels","volume":"25","author":"Mazzitelli","year":"2022","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbi.2024.09.023_b0080","unstructured":"in Data Integration in Learning Health Care Systems for Traumatic Brain Injury: Proceedings of a Workshop. 2024: Washington (DC)."},{"issue":"7","key":"10.1016\/j.bbi.2024.09.023_b0085","doi-asserted-by":"crossref","first-page":"e0159930","DOI":"10.1371\/journal.pone.0159930","article-title":"Endothelial-specific EphA4 negatively regulates native pial collateral formation and re-perfusion following hindlimb ischemia","volume":"11","author":"Okyere","year":"2016","journal-title":"PLoS One"},{"issue":"6301","key":"10.1016\/j.bbi.2024.09.023_b0090","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1126\/science.aaf6260","article-title":"Inflammatory neuroprotection following traumatic brain injury","volume":"353","author":"Russo","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.bbi.2024.09.023_b0095","doi-asserted-by":"crossref","DOI":"10.3389\/fnmol.2021.747770","article-title":"Conditional deletion of EphA4 on Cx3cr1-expressing microglia fails to influence histopathological outcome and blood brain barrier disruption following brain injury","volume":"14","author":"Soliman","year":"2021","journal-title":"Front. Mol. Neurosci."},{"issue":"1","key":"10.1016\/j.bbi.2024.09.023_b0100","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1186\/s12974-023-02940-5","article-title":"Efferocytosis is restricted by axon guidance molecule EphA4 via ERK\/Stat6\/MERTK signaling following brain injury","volume":"20","author":"Soliman","year":"2023","journal-title":"J Neuroinflammation"},{"key":"10.1016\/j.bbi.2024.09.023_b0105","doi-asserted-by":"crossref","first-page":"1334847","DOI":"10.3389\/fneur.2024.1334847","article-title":"Neuroinflammation and acquired traumatic CNS injury: a mini review","volume":"15","author":"Theus","year":"2024","journal-title":"Front. Neurol."},{"issue":"6","key":"10.1016\/j.bbi.2024.09.023_b0110","doi-asserted-by":"crossref","DOI":"10.3390\/biom12060748","article-title":"The underlying role of the glymphatic system and meningeal lymphatic vessels in cerebral small vessel disease","volume":"12","author":"Tian","year":"2022","journal-title":"Biomolecules"},{"issue":"1","key":"10.1016\/j.bbi.2024.09.023_b0115","doi-asserted-by":"crossref","first-page":"52","DOI":"10.2144\/00291bm09","article-title":"Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT)","volume":"29","author":"Truett","year":"2000","journal-title":"Biotechniques"},{"key":"10.1016\/j.bbi.2024.09.023_b0120","unstructured":"Whiting, M.D., A.I. Baranova, R.J. Hamm. (2006). Cognitive Impairment following Traumatic Brain Injury, in Animal Models of Cognitive Impairment, E.D. Levin and J.J. Buccafusco, Editors. Boca Raton (FL)."}],"container-title":["Brain, Behavior, and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159124006263?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159124006263?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T22:26:11Z","timestamp":1747866371000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889159124006263"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":24,"alternative-id":["S0889159124006263"],"URL":"https:\/\/doi.org\/10.1016\/j.bbi.2024.09.023","relation":{},"ISSN":["0889-1591"],"issn-type":[{"value":"0889-1591","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Skull bone marrow-derived immune cells infiltrate the injured cerebral cortex and exhibit anti-inflammatory properties","name":"articletitle","label":"Article Title"},{"value":"Brain, Behavior, and Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbi.2024.09.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}