{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T19:24:20Z","timestamp":1789154660544,"version":"build-2803163510"},"reference-count":167,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T00:00:00Z","timestamp":1729641600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007601","name":"Horizon 2020","doi-asserted-by":"publisher","award":["874583"],"award-info":[{"award-number":["874583"]}],"id":[{"id":"10.13039\/501100007601","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain, Behavior, and Immunity"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.bbi.2024.10.027","type":"journal-article","created":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T16:31:39Z","timestamp":1729528299000},"page":"752-764","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["A systematic approach to identify gaps in neuroimmunology: TNF-\u03b1 and fear learning deficits, a worked example"],"prefix":"10.1016","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8213-7657","authenticated-orcid":false,"given":"Elise J.","family":"Heesbeen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth Y.","family":"Bijlsma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tristan A.","family":"Risseeuw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen V.S.","family":"Hessel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucianne","family":"Groenink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbi.2024.10.027_b0005","unstructured":"Ackerman, S., 1992. Discovering the Brain. Washington (DC)."},{"key":"10.1016\/j.bbi.2024.10.027_b0010","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/(SICI)1098-2396(200002)35:2<151::AID-SYN8>3.0.CO;2-P","article-title":"Evidence for the involvement of TNF and NF-kappaB in hippocampal synaptic plasticity","volume":"35","author":"Albensi","year":"2000","journal-title":"Synapse"},{"key":"10.1016\/j.bbi.2024.10.027_b0015","doi-asserted-by":"crossref","first-page":"6211","DOI":"10.1523\/JNEUROSCI.1246-08.2008","article-title":"Contextual fear conditioning in humans: cortical-hippocampal and amygdala contributions","volume":"28","author":"Alvarez","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0020","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.neuro.2016.05.010","article-title":"Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity","volume":"59","author":"Bal-Price","year":"2017","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.bbi.2024.10.027_b0025","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s00210-009-0421-0","article-title":"NF-kappaB induces PGE2-synthesizing enzymes in neurons","volume":"380","author":"Barakat","year":"2009","journal-title":"Naunyn Schmiedebergs Arch. Pharmacol."},{"key":"10.1016\/j.bbi.2024.10.027_b0030","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1017\/S0033291708003516","article-title":"Influence of trait anxiety on brain activity during the acquisition and extinction of aversive conditioning","volume":"39","author":"Barrett","year":"2009","journal-title":"Psychol. Med."},{"key":"10.1016\/j.bbi.2024.10.027_b0035","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S0166-4328(02)00043-8","article-title":"Memory for context is impaired by a post context exposure injection of interleukin-1 beta into dorsal hippocampus","volume":"134","author":"Barrientos","year":"2002","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.bbi.2024.10.027_b0040","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1017\/S003329171200147X","article-title":"Global prevalence of anxiety disorders: a systematic review and meta-regression","volume":"43","author":"Baxter","year":"2013","journal-title":"Psychol. Med."},{"key":"10.1016\/j.bbi.2024.10.027_b0045","doi-asserted-by":"crossref","first-page":"2282","DOI":"10.1126\/science.1067859","article-title":"Control of synaptic strength by glial TNFalpha","volume":"295","author":"Beattie","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.bbi.2024.10.027_b0050","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.yrtph.2015.04.004","article-title":"Increasing scientific confidence in adverse outcome pathways: application of tailored bradford-hill considerations for evaluating weight of evidence","volume":"72","author":"Becker","year":"2015","journal-title":"Regul. Toxicol. Pharm."},{"key":"10.1016\/j.bbi.2024.10.027_b0055","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0736-5748(94)00061-7","article-title":"Differential regulation of astrocyte TNF-alpha expression by the cytokines TGF-beta, IL-6 and IL-10","volume":"13","author":"Benveniste","year":"1995","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0060","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1038\/34651","article-title":"Prostaglandins stimulate calcium-dependent glutamate release in astrocytes","volume":"391","author":"Bezzi","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.bbi.2024.10.027_b0065","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1038\/89490","article-title":"CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity","volume":"4","author":"Bezzi","year":"2001","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0070","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1016\/j.euroneuro.2015.07.004","article-title":"Lifelong disturbance of serotonin transporter functioning results in fear learning deficits: reversal by blockade of CRF1 receptors","volume":"25","author":"Bijlsma","year":"2015","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.bbi.2024.10.027_b0075","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1176\/ajp.155.9.1178","article-title":"Cerebral glucose metabolism in women with panic disorder","volume":"155","author":"Bisaga","year":"1998","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.bbi.2024.10.027_b0080","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1101\/lm.30901","article-title":"Synaptic plasticity in the lateral amygdala: a cellular hypothesis of fear conditioning","volume":"8","author":"Blair","year":"2001","journal-title":"Learn. Mem."},{"key":"10.1016\/j.bbi.2024.10.027_b0085","doi-asserted-by":"crossref","first-page":"13436","DOI":"10.1523\/JNEUROSCI.4430-07.2007","article-title":"Activation of hippocampal nuclear factor-kappa B by retrieval is required for memory reconsolidation","volume":"27","author":"Boccia","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0090","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S0006-3223(02)01355-0","article-title":"rCBF differences between panic disorder patients and control subjects during anticipatory anxiety and rest","volume":"52","author":"Boshuisen","year":"2002","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2024.10.027_b0095","doi-asserted-by":"crossref","first-page":"14076","DOI":"10.1074\/jbc.M600653200","article-title":"Caspase-3 cleaves and inactivates the glutamate transporter EAAT2","volume":"281","author":"Boston-Howes","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbi.2024.10.027_b0100","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1037\/0033-295X.108.1.4","article-title":"A modern learning theory perspective on the etiology of panic disorder","volume":"108","author":"Bouton","year":"2001","journal-title":"Psychol. Rev."},{"key":"10.1016\/j.bbi.2024.10.027_b0105","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.biopsych.2005.12.015","article-title":"Contextual and temporal modulation of extinction: behavioral and biological mechanisms","volume":"60","author":"Bouton","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2024.10.027_b0110","doi-asserted-by":"crossref","first-page":"2736","DOI":"10.1093\/brain\/awr199","article-title":"Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination","volume":"134","author":"Brambilla","year":"2011","journal-title":"Brain"},{"key":"10.1016\/j.bbi.2024.10.027_b0115","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1176\/appi.ajp.160.5.924","article-title":"MRI and PET study of deficits in hippocampal structure and function in women with childhood sexual abuse and posttraumatic stress disorder","volume":"160","author":"Bremner","year":"2003","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.bbi.2024.10.027_b0120","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1038\/nri3834","article-title":"Regulation of tumour necrosis factor signalling: live or let die","volume":"15","author":"Brenner","year":"2015","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bbi.2024.10.027_b0125","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.biopsych.2004.12.025","article-title":"Corticolimbic blood flow in posttraumatic stress disorder during script-driven imagery","volume":"57","author":"Britton","year":"2005","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2024.10.027_b0130","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2022.957702","article-title":"Alterations of mitochondrial dynamics in serotonin transporter knockout rats: a possible role in the fear extinction recall mechanisms","volume":"16","author":"Brivio","year":"2022","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0135","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1002\/hbm.20415","article-title":"Enhanced amygdala and medial prefrontal activation during nonconscious processing of fear in posttraumatic stress disorder: an fMRI study","volume":"29","author":"Bryant","year":"2008","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.bbi.2024.10.027_b0140","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.neuron.2007.02.021","article-title":"Consolidation of fear extinction requires NMDA receptor-dependent bursting in the ventromedial prefrontal cortex","volume":"53","author":"Burgos-Robles","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.bbi.2024.10.027_b0145","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0896-6273(92)90120-3","article-title":"Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit","volume":"8","author":"Burnashev","year":"1992","journal-title":"Neuron"},{"key":"10.1016\/j.bbi.2024.10.027_b0150","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/ncb2883","article-title":"Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis","volume":"16","author":"Cai","year":"2014","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.bbi.2024.10.027_b0155","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1037\/0735-7044.106.3.569","article-title":"Intra-amygdala infusion of the N-methyl-D-aspartate receptor antagonist AP5 blocks acquisition but not expression of fear-potentiated startle to an auditory conditioned stimulus","volume":"106","author":"Campeau","year":"1992","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0160","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1196\/annals.1432.020","article-title":"Chronic low-dose oxidative stress induces caspase-3-dependent PKCdelta proteolytic activation and apoptosis in a cell culture model of dopaminergic neurodegeneration","volume":"1139","author":"Carvour","year":"2008","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.bbi.2024.10.027_b0165","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.neulet.2013.02.005","article-title":"The contribution of TNF-alpha in the amygdala to anxiety in mice with persistent inflammatory pain","volume":"541","author":"Chen","year":"2013","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.bbi.2024.10.027_b0170","doi-asserted-by":"crossref","first-page":"16247","DOI":"10.1074\/jbc.M112.435545","article-title":"Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling","volume":"288","author":"Chen","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbi.2024.10.027_b0175","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1037\/0735-7044.120.5.1187","article-title":"Human amygdala activity during the expression of fear responses","volume":"120","author":"Cheng","year":"2006","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0180","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1016\/j.cell.2009.05.037","article-title":"Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation","volume":"137","author":"Cho","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.bbi.2024.10.027_b0185","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1002\/neu.480230915","article-title":"Excitotoxic cell death","volume":"23","author":"Choi","year":"1992","journal-title":"J. Neurobiol."},{"key":"10.1016\/j.bbi.2024.10.027_b0190","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/j.1749-6632.1994.tb21789.x","article-title":"Induction of superoxide anion and nitric oxide production in cultured microglia","volume":"738","author":"Colton","year":"1994","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.bbi.2024.10.027_b0195","doi-asserted-by":"crossref","first-page":"2416","DOI":"10.1038\/sj.npp.1301642","article-title":"Disruption of AMPA receptor endocytosis impairs the extinction, but not acquisition of learned fear","volume":"33","author":"Dalton","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbi.2024.10.027_b0200","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.neuropharm.2011.09.001","article-title":"NMDA GluN2A and GluN2B receptors play separate roles in the induction of LTP and LTD in the amygdala and in the acquisition and extinction of conditioned fear","volume":"62","author":"Dalton","year":"2012","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.bbi.2024.10.027_b0205","doi-asserted-by":"crossref","first-page":"4572","DOI":"10.1073\/pnas.1400423111","article-title":"Hippocampal molecular mechanisms involved in the enhancement of fear extinction caused by exposure to novelty","volume":"111","author":"de Carvalho Myskiw","year":"2014","journal-title":"PNAS"},{"key":"10.1016\/j.bbi.2024.10.027_b0210","doi-asserted-by":"crossref","first-page":"50","DOI":"10.3389\/fnmol.2015.00050","article-title":"NF-kappaB transcription factor role in consolidation and reconsolidation of persistent memories","volume":"8","author":"de la Fuente","year":"2015","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0215","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.autrev.2016.07.022","article-title":"Parkinson's disease: autoimmunity and neuroinflammation","volume":"15","author":"De Virgilio","year":"2016","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.bbi.2024.10.027_b0220","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0896-6273(02)01001-2","article-title":"Cellular and systems reconsolidation in the hippocampus","volume":"36","author":"Debiec","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.bbi.2024.10.027_b0225","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.celrep.2014.04.026","article-title":"MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates","volume":"7","author":"Dondelinger","year":"2014","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbi.2024.10.027_b0230","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1038\/aps.2009.24","article-title":"Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases","volume":"30","author":"Dong","year":"2009","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.bbi.2024.10.027_b0235","doi-asserted-by":"crossref","DOI":"10.3390\/ijms18102226","article-title":"Diurnal hypothalamic-pituitary-adrenal axis measures and inflammatory marker correlates in major depressive disorder","volume":"18","author":"Doolin","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbi.2024.10.027_b0240","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1037\/0735-7044.121.4.635","article-title":"Impact of continuous versus intermittent CS-UCS pairing on human brain activation during Pavlovian fear conditioning","volume":"121","author":"Dunsmoor","year":"2007","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0245","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1523\/JNEUROSCI.12-03-00854.1992","article-title":"Extinction of fear-potentiated startle: blockade by infusion of an NMDA antagonist into the amygdala","volume":"12","author":"Falls","year":"1992","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0250","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1037\/0735-7044.108.1.210","article-title":"Acquisition of contextual Pavlovian fear conditioning is blocked by application of an NMDA receptor antagonist D, L-2-amino-5-phosphonovaleric acid to the basolateral amygdala","volume":"108","author":"Fanselow","year":"1994","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0255","doi-asserted-by":"crossref","first-page":"4111","DOI":"10.1523\/JNEUROSCI.21-11-04111.2001","article-title":"Injections of the NMDA receptor antagonist aminophosphonopentanoic acid into the lateral nucleus of the amygdala block the expression of fear-potentiated startle and freezing","volume":"21","author":"Fendt","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0260","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/nature18626","article-title":"Unexpected role of interferon-gamma in regulating neuronal connectivity and social behaviour","volume":"535","author":"Filiano","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.bbi.2024.10.027_b0265","doi-asserted-by":"crossref","first-page":"2566","DOI":"10.1523\/JNEUROSCI.4998-04.2005","article-title":"Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors","volume":"25","author":"Floden","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0270","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1111\/j.1460-9568.2005.04126.x","article-title":"NF-kappaB transcription factor is required for inhibitory avoidance long-term memory in mice","volume":"21","author":"Freudenthal","year":"2005","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0275","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1046\/j.1471-4159.1998.70051876.x","article-title":"The transcription factor NF-kappaB mediates increases in calcium currents and decreases in NMDA- and AMPA\/kainate-induced currents induced by tumor necrosis factor-alpha in hippocampal neurons","volume":"70","author":"Furukawa","year":"1998","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbi.2024.10.027_b0280","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1096\/fj.05-3776fje","article-title":"Exaggerated neuroinflammation and sickness behavior in aged mice following activation of the peripheral innate immune system","volume":"19","author":"Godbout","year":"2005","journal-title":"FASEB J."},{"key":"10.1016\/j.bbi.2024.10.027_b0285","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.bbi.2019.07.003","article-title":"Interplay between inflammation and neural plasticity: both immune activation and suppression impair LTP and BDNF expression","volume":"81","author":"Golia","year":"2019","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbi.2024.10.027_b0290","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/0006-8993(94)90883-4","article-title":"TNF-alpha increases the frequency of spontaneous miniature synaptic currents in cultured rat hippocampal neurons","volume":"659","author":"Grassi","year":"1994","journal-title":"Brain Res."},{"key":"10.1016\/j.bbi.2024.10.027_b0295","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1016\/j.cell.2015.11.023","article-title":"Neuroinflammatory TNFalpha impairs memory via astrocyte signaling","volume":"163","author":"Habbas","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.bbi.2024.10.027_b0300","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.bbr.2014.08.052","article-title":"Intra-amygdala microinfusion of IL-6 impairs the auditory fear conditioning of rats via JAK\/STAT activation","volume":"275","author":"Hao","year":"2014","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.bbi.2024.10.027_b0305","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/j.cell.2009.05.021","article-title":"Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha","volume":"137","author":"He","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.bbi.2024.10.027_b0310","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1007\/s00213-023-06333-7","article-title":"The effect of SSRIs on fear learning: a systematic review and meta-analysis","volume":"240","author":"Heesbeen","year":"2023","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.bbi.2024.10.027_b0315","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2567.2005.02143.x","article-title":"The intriguing biology of the tumour necrosis factor\/tumour necrosis factor receptor superfamily: players, rules and the games","volume":"115","author":"Hehlgans","year":"2005","journal-title":"Immunology"},{"key":"10.1016\/j.bbi.2024.10.027_b0320","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2020.565841","article-title":"TNF-mediated homeostatic synaptic plasticity: from in vitro to in vivo models","volume":"14","author":"Heir","year":"2020","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0325","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1742-2094-3-2","article-title":"Primary glia expressing the G93A-SOD1 mutation present a neuroinflammatory phenotype and provide a cellular system for studies of glial inflammation","volume":"3","author":"Hensley","year":"2006","journal-title":"J. Neuroinflamm."},{"key":"10.1016\/j.bbi.2024.10.027_b0330","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.taap.2018.03.013","article-title":"Design and validation of an ontology-driven animal-free testing strategy for developmental neurotoxicity testing","volume":"354","author":"Hessel","year":"2018","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.bbi.2024.10.027_b0335","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.22-06-j0001.2002","article-title":"Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS","volume":"22","author":"Higgins","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0340","doi-asserted-by":"crossref","first-page":"15072","DOI":"10.1073\/pnas.1408987111","article-title":"Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death","volume":"111","author":"Hildebrand","year":"2014","journal-title":"PNAS"},{"key":"10.1016\/j.bbi.2024.10.027_b0345","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.brainres.2007.01.089","article-title":"Brain responses to symptom provocation and trauma-related short-term memory recall in coal mining accident survivors with acute severe PTSD","volume":"1144","author":"Hou","year":"2007","journal-title":"Brain Res."},{"key":"10.1016\/j.bbi.2024.10.027_b0350","article-title":"Stress-related immune markers in depression: implications for treatment","volume":"19","author":"Hughes","year":"2016","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.bbi.2024.10.027_b0355","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.neures.2014.10.015","article-title":"Intra-amygdala microinjection of TNF-alpha impairs the auditory fear conditioning of rats via glutamate toxicity","volume":"91","author":"Jing","year":"2015","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.bbi.2024.10.027_b0360","doi-asserted-by":"crossref","first-page":"9503","DOI":"10.1523\/JNEUROSCI.2021-06.2006","article-title":"Context-dependent human extinction memory is mediated by a ventromedial prefrontal and hippocampal network","volume":"26","author":"Kalisch","year":"2006","journal-title":"J. Neurosci."},{"issue":"11","key":"10.1016\/j.bbi.2024.10.027_b0827","doi-asserted-by":"crossref","first-page":"4474","DOI":"10.1038\/s41380-022-01737-x","article-title":"Sustained TNF signaling is required for the synaptic and anxiety-like behavioral response to acute stress","volume":"27","author":"Kemp","year":"2022","journal-title":"Molecular psychiatry"},{"key":"10.1016\/j.bbi.2024.10.027_b0365","series-title":"Encyclopedia of Quality of Life and Well-Being Research","first-page":"974","article-title":"Cognitive function","author":"Kiely","year":"2014"},{"key":"10.1016\/j.bbi.2024.10.027_b0370","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.bbi.2016.08.001","article-title":"Differential effects of peripheral and brain tumor necrosis factor on inflammation, sickness, emotional behavior and memory in mice","volume":"58","author":"Klaus","year":"2016","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbi.2024.10.027_b0375","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.yrtph.2016.01.007","article-title":"Adverse outcome pathways: from research to regulation scientific workshop report","volume":"76","author":"Kleinstreuer","year":"2016","journal-title":"Regul. Toxicol. Pharm."},{"key":"10.1016\/j.bbi.2024.10.027_b0380","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.biopsycho.2011.10.018","article-title":"Genetic variation in serotonin transporter function affects human fear expression indexed by fear-potentiated startle","volume":"89","author":"Klumpers","year":"2012","journal-title":"Biol. Psychol."},{"key":"10.1016\/j.bbi.2024.10.027_b0385","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/npp.2013.191","article-title":"Learning not to fear: neural correlates of learned safety","volume":"39","author":"Kong","year":"2014","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbi.2024.10.027_b0390","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.bbi.2011.08.005","article-title":"Peripheral bacterial endotoxin administration triggers both memory consolidation and reconsolidation deficits in mice","volume":"26","author":"Kranjac","year":"2012","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbi.2024.10.027_b0395","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.jneuroim.2005.01.015","article-title":"Autocrine activation of microglia by tumor necrosis factor-alpha","volume":"162","author":"Kuno","year":"2005","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.bbi.2024.10.027_b0400","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.neuroscience.2006.10.046","article-title":"Microglia and macrophages express tumor necrosis factor receptor p75 following middle cerebral artery occlusion in mice","volume":"144","author":"Lambertsen","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbi.2024.10.027_b0405","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1101\/lm.928208","article-title":"The basolateral amygdala is necessary for learning but not relearning extinction of context conditioned fear","volume":"15","author":"Laurent","year":"2008","journal-title":"Learn. Mem."},{"key":"10.1016\/j.bbi.2024.10.027_b0410","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1101\/lm.1080108","article-title":"Distinct contributions of the basolateral amygdala and the medial prefrontal cortex to learning and relearning extinction of context conditioned fear","volume":"15","author":"Laurent","year":"2008","journal-title":"Learn. Mem."},{"key":"10.1016\/j.bbi.2024.10.027_b0415","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1101\/lm.1474609","article-title":"Inactivation of the infralimbic but not the prelimbic cortex impairs consolidation and retrieval of fear extinction","volume":"16","author":"Laurent","year":"2009","journal-title":"Learn. Mem."},{"key":"10.1016\/j.bbi.2024.10.027_b0420","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1038\/s41467-020-15466-8","article-title":"Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation","volume":"11","author":"Laurien","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbi.2024.10.027_b0425","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/j.biopsych.2005.01.023","article-title":"D-cycloserine facilitates extinction of learned fear: effects on reacquisition and generalized extinction","volume":"57","author":"Ledgerwood","year":"2005","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2024.10.027_b0430","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1523\/JNEUROSCI.5159-07.2008","article-title":"Rapid tumor necrosis factor alpha-induced exocytosis of glutamate receptor 2-lacking AMPA receptors to extrasynaptic plasma membrane potentiates excitotoxicity","volume":"28","author":"Leonoudakis","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0435","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1038\/s41386-018-0064-2","article-title":"Repeated social defeat-induced neuroinflammation, anxiety-like behavior and resistance to fear extinction were attenuated by the cannabinoid receptor agonist WIN55,212\u20132","volume":"43","author":"Lisboa","year":"2018","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbi.2024.10.027_b0440","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.biopsych.2013.07.025","article-title":"Generalized anxiety disorder is associated with overgeneralization of classically conditioned fear","volume":"75","author":"Lissek","year":"2014","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2024.10.027_b0445","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1016\/j.peptides.2010.07.018","article-title":"alpha-Melanocyte-stimulating hormone (alpha-MSH) reverses impairment of memory reconsolidation induced by interleukin-1 beta (IL-1 beta) hippocampal infusions","volume":"31","author":"Machado","year":"2010","journal-title":"Peptides"},{"key":"10.1016\/j.bbi.2024.10.027_b0450","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.bbi.2015.01.012","article-title":"Interleukin-1beta-induced memory reconsolidation impairment is mediated by a reduction in glutamate release and zif268 expression and alpha-melanocyte-stimulating hormone prevented these effects","volume":"46","author":"Machado","year":"2015","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbi.2024.10.027_b0455","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.neuropharm.2017.09.041","article-title":"IL-1beta reduces GluA1 phosphorylation and its surface expression during memory reconsolidation and alpha-melanocyte-stimulating hormone can modulate these effects","volume":"128","author":"Machado","year":"2018","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.bbi.2024.10.027_b0460","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1007\/s11064-012-0967-y","article-title":"The pro-inflammatory cytokine TNF-alpha regulates the activity and expression of the serotonin transporter (SERT) in astrocytes","volume":"38","author":"Malynn","year":"2013","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.bbi.2024.10.027_b0465","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1002\/(SICI)1097-4547(19970915)49:6<681::AID-JNR3>3.0.CO;2-3","article-title":"Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration","volume":"49","author":"Mattson","year":"1997","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.bbi.2024.10.027_b0470","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1001\/archpsyc.64.1.97","article-title":"Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorder","volume":"64","author":"McClure","year":"2007","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.bbi.2024.10.027_b0475","doi-asserted-by":"crossref","first-page":"2422","DOI":"10.1523\/JNEUROSCI.4001-13.2014","article-title":"Reconsolidation and extinction are dissociable and mutually exclusive processes: behavioral and molecular evidence","volume":"34","author":"Merlo","year":"2014","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0480","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0092-8674(03)00521-X","article-title":"Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes","volume":"114","author":"Micheau","year":"2003","journal-title":"Cell"},{"key":"10.1016\/j.bbi.2024.10.027_b0485","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/npp.2016.146","article-title":"Inflammation in fear- and anxiety-based disorders: PTSD, GAD, and beyond","volume":"42","author":"Michopoulos","year":"2017","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbi.2024.10.027_b0490","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.jpsychires.2008.01.017","article-title":"Presence and acquired origin of reduced recall for fear extinction in PTSD: results of a twin study","volume":"42","author":"Milad","year":"2008","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.bbi.2024.10.027_b0495","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/nature01138","article-title":"Neurons in medial prefrontal cortex signal memory for fear extinction","volume":"420","author":"Milad","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.bbi.2024.10.027_b0500","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.neuroscience.2009.05.049","article-title":"Tumor necrosis factor alpha and interferon gamma cooperatively induce oxidative stress and motoneuron death in rat spinal cord embryonic explants","volume":"162","author":"Mir","year":"2009","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbi.2024.10.027_b0505","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0006-8993(01)03124-9","article-title":"Na+ dependent glutamate transporters (EAAT1, EAAT2, and EAAT3) in primary astrocyte cultures: effect of oxidative stress","volume":"922","author":"Miralles","year":"2001","journal-title":"Brain Res."},{"key":"10.1016\/j.bbi.2024.10.027_b0510","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1001\/archpsyc.65.5.568","article-title":"Amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorder","volume":"65","author":"Monk","year":"2008","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.bbi.2024.10.027_b0515","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.bbr.2013.10.006","article-title":"Analysis of cognition, motor performance and anxiety in young and aged tumor necrosis factor alpha receptor 1 and 2 deficient mice","volume":"258","author":"Naude","year":"2014","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.bbi.2024.10.027_b0520","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1176\/appi.ajp.2008.07101682","article-title":"Anticipatory activation in the amygdala and anterior cingulate in generalized anxiety disorder and prediction of treatment response","volume":"166","author":"Nitschke","year":"2009","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.bbi.2024.10.027_b0525","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/S0006-3223(98)00026-2","article-title":"Regional cerebral metabolic asymmetries replicated in an independent group of patients with panic disorders","volume":"44","author":"Nordahl","year":"1998","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2024.10.027_b0530","doi-asserted-by":"crossref","DOI":"10.1289\/EHP5297","article-title":"Evaluating chemicals for thyroid disruption: opportunities and challenges with in vitro testing and adverse outcome pathway approaches","volume":"127","author":"Noyes","year":"2019","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.bbi.2024.10.027_b0535","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.expneurol.2004.12.026","article-title":"Tumor necrosis-factor-alpha (TNF-alpha) induces rapid insertion of Ca2+-permeable alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA)\/kainate (Ca-A\/K) channels in a subset of hippocampal pyramidal neurons","volume":"193","author":"Ogoshi","year":"2005","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bbi.2024.10.027_b0540","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1037\/0021-843X.109.2.290","article-title":"De novo conditioning in trauma-exposed individuals with and without posttraumatic stress disorder","volume":"109","author":"Orr","year":"2000","journal-title":"J. Abnorm. Psychol."},{"issue":"6","key":"10.1016\/j.bbi.2024.10.027_b0826","doi-asserted-by":"crossref","first-page":"2963","DOI":"10.1007\/s12035-021-02322-z","article-title":"Hippocampal TNF-\u03b1 Signaling Mediates Heroin Withdrawal-Enhanced Fear Learning and Withdrawal-Induced Weight Loss","volume":"58","author":"Parekh","year":"2021","journal-title":"Molecular neurobiology"},{"key":"10.1016\/j.bbi.2024.10.027_b0545","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.nlm.2005.01.001","article-title":"Effects of multiple exposures to D-cycloserine on extinction of conditioned fear in rats","volume":"83","author":"Parnas","year":"2005","journal-title":"Neurobiol. Learn. Mem."},{"issue":"625\u2013640","key":"10.1016\/j.bbi.2024.10.027_b0550","article-title":"Microglia require CD4 T cells to complete the fetal-to-adult transition","volume":"182","author":"Pasciuto","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.bbi.2024.10.027_b0555","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.biopsych.2006.03.042","article-title":"An insular view of anxiety","volume":"60","author":"Paulus","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2024.10.027_b0560","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1038\/npp.2010.231","article-title":"Acquisition of Pavlovian fear conditioning using beta-adrenoceptor activation of the dorsal premammillary nucleus as an unconditioned stimulus to mimic live predator-threat exposure","volume":"36","author":"Pavesi","year":"2011","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbi.2024.10.027_b0565","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/S0006-3223(99)00144-4","article-title":"Psychophysiologic assessment of aversive conditioning in posttraumatic stress disorder","volume":"47","author":"Peri","year":"2000","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2024.10.027_b0570","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.cotox.2019.03.009","article-title":"The virtual human in chemical safety assessment","volume":"15","author":"Piersma","year":"2019","journal-title":"Curr. Opin. Toxicol."},{"key":"10.1016\/j.bbi.2024.10.027_b0575","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.janxdis.2006.04.001","article-title":"Recognition of happy facial affect in panic disorder: an fMRI study","volume":"21","author":"Pillay","year":"2007","journal-title":"J. Anxiety Disord."},{"key":"10.1016\/j.bbi.2024.10.027_b0580","doi-asserted-by":"crossref","first-page":"e200418","DOI":"10.2903\/j.efsa.2022.e200418","article-title":"Assessment of endocrine disruptive properties of PFOS: EFSA\/ECHA guidance case study utilising AOP networks and alternative methods","volume":"20","author":"Pipal","year":"2022","journal-title":"EFSA J."},{"key":"10.1016\/j.bbi.2024.10.027_b0585","doi-asserted-by":"crossref","DOI":"10.1016\/j.jneumeth.2020.108766","article-title":"Protocols for instrumental memory reconsolidation in rodents: a methodological review","volume":"342","author":"Piva","year":"2020","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.bbi.2024.10.027_b0590","doi-asserted-by":"crossref","first-page":"15879","DOI":"10.1523\/JNEUROSCI.0530-13.2013","article-title":"TNF-alpha downregulates inhibitory neurotransmission through protein phosphatase 1-dependent trafficking of GABA(A) receptors","volume":"33","author":"Pribiag","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0595","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.biopsych.2004.12.026","article-title":"Differential time courses and specificity of amygdala activity in posttraumatic stress disorder subjects and normal control subjects","volume":"57","author":"Protopopescu","year":"2005","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2024.10.027_b0600","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1037\/0033-2909.86.3.638","article-title":"The file drawer problem and tolerance for null results","volume":"86","author":"Rosenthal","year":"1979","journal-title":"Psychol. Bull."},{"key":"10.1016\/j.bbi.2024.10.027_b0605","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.taap.2018.02.024","article-title":"Development of the Adverse Outcome Pathway (AOP): Chronic binding of antagonist to N-methyl-d-aspartate receptors (NMDARs) during brain development induces impairment of learning and memory abilities of children","volume":"354","author":"Sachana","year":"2018","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.bbi.2024.10.027_b0610","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1097\/00001756-200506210-00010","article-title":"Cerebral glucose metabolism associated with a fear network in panic disorder","volume":"16","author":"Sakai","year":"2005","journal-title":"Neuroreport"},{"key":"10.1016\/j.bbi.2024.10.027_b0615","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1038\/s41577-021-00508-z","article-title":"Neuromodulation by the immune system: a focus on cytokines","volume":"21","author":"Salvador","year":"2021","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bbi.2024.10.027_b0620","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1111\/cns.12822","article-title":"Impaired fear extinction in serotonin transporter knockout rats is associated with increased 5-hydroxymethylcytosine in the amygdala","volume":"24","author":"Shan","year":"2018","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.bbi.2024.10.027_b0625","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/npp.2009.83","article-title":"The neurocircuitry of fear, stress, and anxiety disorders","volume":"35","author":"Shin","year":"2010","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbi.2024.10.027_b0630","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0043973","article-title":"Activation of NF-kappaB in basolateral amygdala is required for memory reconsolidation in auditory fear conditioning","volume":"7","author":"Si","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bbi.2024.10.027_b0635","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.biopsych.2005.10.013","article-title":"TNFalpha signaling in depression and anxiety: behavioral consequences of individual receptor targeting","volume":"59","author":"Simen","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2024.10.027_b0640","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1038\/sj.emboj.7600555","article-title":"Positive and negative regulation of EAAT2 by NF-kappaB: a role for N-myc in TNFalpha-controlled repression","volume":"24","author":"Sitcheran","year":"2005","journal-title":"EMBO J."},{"key":"10.1016\/j.bbi.2024.10.027_b0645","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1093\/cercor\/bhn099","article-title":"Dissociable roles for the ventromedial prefrontal cortex and amygdala in fear extinction: NR2B contribution","volume":"19","author":"Sotres-Bayon","year":"2009","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.bbi.2024.10.027_b0650","doi-asserted-by":"crossref","first-page":"2759","DOI":"10.1007\/s00204-019-02551-1","article-title":"Development and analysis of an adverse outcome pathway network for human neurotoxicity","volume":"93","author":"Spinu","year":"2019","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.bbi.2024.10.027_b0655","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a021766","article-title":"Memory consolidation","volume":"7","author":"Squire","year":"2015","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.bbi.2024.10.027_b0660","doi-asserted-by":"crossref","first-page":"3219","DOI":"10.1523\/JNEUROSCI.4486-04.2005","article-title":"Differential regulation of AMPA receptor and GABA receptor trafficking by tumor necrosis factor-alpha","volume":"25","author":"Stellwagen","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0665","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1016\/j.str.2014.07.014","article-title":"A plug release mechanism for membrane permeation by MLKL","volume":"22","author":"Su","year":"2014","journal-title":"Structure"},{"key":"10.1016\/j.bbi.2024.10.027_b0670","doi-asserted-by":"crossref","first-page":"9505","DOI":"10.1074\/jbc.M109488200","article-title":"Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3","volume":"277","author":"Sun","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbi.2024.10.027_b0675","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1016\/j.scitotenv.2010.12.029","article-title":"Why and how to combine evidence in environmental assessments: weighing evidence and building cases","volume":"409","author":"Suter","year":"2011","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.bbi.2024.10.027_b0680","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1093\/toxsci\/kfab113","article-title":"A pragmatic approach to adverse outcome pathway development and evaluation","volume":"184","author":"Svingen","year":"2021","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.bbi.2024.10.027_b0685","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.bbi.2021.02.033","article-title":"Tumor necrosis factor alpha negatively regulates the retrieval and reconsolidation of hippocampus-dependent memory","volume":"94","author":"Takahashi","year":"2021","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbi.2024.10.027_b0690","doi-asserted-by":"crossref","first-page":"121","DOI":"10.2131\/jts.48.121","article-title":"Amelioration of lipopolysaccharides-induced impairment of fear memory acquisition by alpha-glycosyl isoquercitrin through suppression of neuroinflammation in rats","volume":"48","author":"Tang","year":"2023","journal-title":"J. Toxicol. Sci."},{"key":"10.1016\/j.bbi.2024.10.027_b0695","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/0092-8674(93)90464-2","article-title":"A novel domain within the 55 kd TNF receptor signals cell death","volume":"74","author":"Tartaglia","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.bbi.2024.10.027_b0700","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.pscychresns.2008.03.003","article-title":"Increased activation of the left hippocampus region in Complex PTSD during encoding and recognition of emotional words: a pilot study","volume":"171","author":"Thomaes","year":"2009","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.bbi.2024.10.027_b0705","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0895-4356(99)00161-4","article-title":"Publication bias in meta-analysis: its causes and consequences","volume":"53","author":"Thornton","year":"2000","journal-title":"J. Clin. Epidemiol."},{"key":"10.1016\/j.bbi.2024.10.027_b0710","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.mcn.2010.09.001","article-title":"TNF-alpha potentiates glutamate-induced spinal cord motoneuron death via NF-kappaB","volume":"46","author":"Tolosa","year":"2011","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0715","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/S0165-6147(98)01230-9","article-title":"Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration?","volume":"19","author":"Trotti","year":"1998","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.bbi.2024.10.027_b0720","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1126\/science.274.5288.787","article-title":"Suppression of TNF-alpha-induced apoptosis by NF-kappaB","volume":"274","author":"Van Antwerp","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.bbi.2024.10.027_b0725","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1001\/archpsyc.62.8.922","article-title":"Disorder-specific neuroanatomical correlates of attentional bias in obsessive-compulsive disorder, panic disorder, and hypochondriasis","volume":"62","author":"van den Heuvel","year":"2005","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.bbi.2024.10.027_b0730","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.mcn.2010.06.014","article-title":"Activation of TNF receptor 2 in microglia promotes induction of anti-inflammatory pathways","volume":"45","author":"Veroni","year":"2010","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0735","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.tox.2013.08.011","article-title":"The adverse outcome pathway concept: a pragmatic tool in toxicology","volume":"312","author":"Vinken","year":"2013","journal-title":"Toxicology"},{"key":"10.1016\/j.bbi.2024.10.027_b0740","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2021.152846","article-title":"Safer chemicals using less animals: kick-off of the European ONTOX project","volume":"458","author":"Vinken","year":"2021","journal-title":"Toxicology"},{"key":"10.1016\/j.bbi.2024.10.027_b0745","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.jpsychires.2006.06.009","article-title":"Evidence for low-grade systemic proinflammatory activity in patients with posttraumatic stress disorder","volume":"41","author":"von Kanel","year":"2007","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.bbi.2024.10.027_b0750","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/sj.cdd.4401189","article-title":"Tumor necrosis factor signaling","volume":"10","author":"Wajant","year":"2003","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.bbi.2024.10.027_b0755","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1111\/j.1742-4658.2011.08015.x","article-title":"TNFR1-induced activation of the classical NF-kappaB pathway","volume":"278","author":"Wajant","year":"2011","journal-title":"FEBS J."},{"key":"10.1016\/j.bbi.2024.10.027_b0760","doi-asserted-by":"crossref","first-page":"2343","DOI":"10.1523\/JNEUROSCI.22-06-02343.2002","article-title":"Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of D-cycloserine as assessed with fear-potentiated startle in rats","volume":"22","author":"Walker","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0765","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.cell.2008.03.036","article-title":"TNF-alpha induces two distinct caspase-8 activation pathways","volume":"133","author":"Wang","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.bbi.2024.10.027_b0770","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S0042-6822(03)00181-8","article-title":"Reduced expression of glutamate transporter EAAT2 and impaired glutamate transport in human primary astrocytes exposed to HIV-1 or gp120","volume":"312","author":"Wang","year":"2003","journal-title":"Virology"},{"key":"10.1016\/j.bbi.2024.10.027_b0775","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.molcel.2014.03.003","article-title":"Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3","volume":"54","author":"Wang","year":"2014","journal-title":"Mol. Cell"},{"key":"10.1016\/j.bbi.2024.10.027_b0780","doi-asserted-by":"crossref","first-page":"365","DOI":"10.3389\/fcell.2020.00365","article-title":"The balance of TNF mediated pathways regulates inflammatory cell death signaling in healthy and diseased tissues","volume":"8","author":"Webster","year":"2020","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.bbi.2024.10.027_b0785","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1111\/j.1471-4159.2009.06038.x","article-title":"Tumor necrosis factor-alpha-induced neutral sphingomyelinase-2 modulates synaptic plasticity by controlling the membrane insertion of NMDA receptors","volume":"109","author":"Wheeler","year":"2009","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbi.2024.10.027_b0790","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1038\/cdd.2014.77","article-title":"Distinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosis","volume":"21","author":"Wu","year":"2014","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.bbi.2024.10.027_b0795","doi-asserted-by":"crossref","first-page":"46720","DOI":"10.1074\/jbc.M206258200","article-title":"A requirement of nuclear factor-kappaB activation in fear-potentiated startle","volume":"277","author":"Yeh","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbi.2024.10.027_b0800","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1124\/mol.65.5.1286","article-title":"Acetylation of nuclear factor-kappaB in rat amygdala improves long-term but not short-term retention of fear memory","volume":"65","author":"Yeh","year":"2004","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.bbi.2024.10.027_b0805","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1006\/nbdi.2002.0530","article-title":"Tumor necrosis factor alpha increases neuronal vulnerability to excitotoxic necrosis by inducing expression of the AMPA-glutamate receptor subunit GluR1 via an acid sphingomyelinase- and NF-kappaB-dependent mechanism","volume":"11","author":"Yu","year":"2002","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.bbi.2024.10.027_b0810","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1038\/sj.npp.1301029","article-title":"The proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha activate serotonin transporters","volume":"31","author":"Zhu","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbi.2024.10.027_b0815","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1111\/j.1460-9568.2010.07223.x","article-title":"NMDA receptor antagonism in the basolateral but not central amygdala blocks the extinction of Pavlovian fear conditioning in rats","volume":"31","author":"Zimmerman","year":"2010","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.bbi.2024.10.027_b0820","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0959-4388(99)80045-2","article-title":"Calcium- and activity-dependent synaptic plasticity","volume":"9","author":"Zucker","year":"1999","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.bbi.2024.10.027_b0825","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1523\/JNEUROSCI.3842-06.2007","article-title":"Facilitation of extinction learning for contextual fear memory by PEPA: a potentiator of AMPA receptors","volume":"27","author":"Zushida","year":"2007","journal-title":"J. Neurosci."}],"container-title":["Brain, Behavior, and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159124006688?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159124006688?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T22:39:46Z","timestamp":1747867186000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889159124006688"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":167,"alternative-id":["S0889159124006688"],"URL":"https:\/\/doi.org\/10.1016\/j.bbi.2024.10.027","relation":{},"ISSN":["0889-1591"],"issn-type":[{"value":"0889-1591","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A systematic approach to identify gaps in neuroimmunology: TNF-\u03b1 and fear learning deficits, a worked example","name":"articletitle","label":"Article Title"},{"value":"Brain, Behavior, and Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbi.2024.10.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}