{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:38:55Z","timestamp":1792795135989,"version":"4.5.0"},"reference-count":95,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,3]],"date-time":"2025-02-03T00:00:00Z","timestamp":1738540800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004528","name":"Maastricht Universitair Medisch Centrum","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004528","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016244","name":"Health Foundation Limburg","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016244","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100030866","name":"Transcan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100030866","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000321","name":"World Cancer Research Fund","doi-asserted-by":"publisher","award":["IIG_FULL_2020_018"],"award-info":[{"award-number":["IIG_FULL_2020_018"]}],"id":[{"id":"10.13039\/501100000321","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000321","name":"World Cancer Research Fund","doi-asserted-by":"publisher","award":["2016\/1620"],"award-info":[{"award-number":["2016\/1620"]}],"id":[{"id":"10.13039\/501100000321","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000321","name":"World Cancer Research Fund","doi-asserted-by":"publisher","award":["SG_2021_076"],"award-info":[{"award-number":["SG_2021_076"]}],"id":[{"id":"10.13039\/501100000321","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004622","name":"Dutch Cancer Society","doi-asserted-by":"publisher","award":["UM 2014\\u20136877"],"award-info":[{"award-number":["UM 2014\\u20136877"]}],"id":[{"id":"10.13039\/501100004622","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004622","name":"Dutch Cancer Society","doi-asserted-by":"publisher","award":["2021\\u20131\/13387"],"award-info":[{"award-number":["2021\\u20131\/13387"]}],"id":[{"id":"10.13039\/501100004622","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004622","name":"Dutch Cancer Society","doi-asserted-by":"publisher","award":["UM 2010\\u20134867"],"award-info":[{"award-number":["UM 2010\\u20134867"]}],"id":[{"id":"10.13039\/501100004622","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013514","name":"Wereld Kanker Onderzoek Fonds","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013514","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014477","name":"National Health Insurance Administration","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014477","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014065","name":"Fundaci\u00f3n Focus","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013781","name":"Prince Mohammad Bin Fahd University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001835","name":"Universiteit Maastricht","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001835","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Federal Ministry of Education and Research Bonn Office","doi-asserted-by":"publisher","award":["01KT1503"],"award-info":[{"award-number":["01KT1503"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Federal Ministry of Education and Research Bonn Office","doi-asserted-by":"publisher","award":["01KD2101D"],"award-info":[{"award-number":["01KD2101D"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013743","name":"World Cancer Research Fund International","doi-asserted-by":"publisher","award":["00005739"],"award-info":[{"award-number":["00005739"]}],"id":[{"id":"10.13039\/100013743","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Institutes of Health National Cancer Institute","doi-asserted-by":"publisher","award":["U01 CA206110"],"award-info":[{"award-number":["U01 CA206110"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Institutes of Health National Cancer Institute","doi-asserted-by":"publisher","award":["R01 CA189184"],"award-info":[{"award-number":["R01 CA189184"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Institutes of Health National Cancer Institute","doi-asserted-by":"publisher","award":["R01 CA254108"],"award-info":[{"award-number":["R01 CA254108"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Institutes of Health National Cancer Institute","doi-asserted-by":"publisher","award":["R01 CA211705"],"award-info":[{"award-number":["R01 CA211705"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Institutes of Health National Cancer Institute","doi-asserted-by":"publisher","award":["R01 CA207371"],"award-info":[{"award-number":["R01 CA207371"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Institutes of Health National Cancer Institute","doi-asserted-by":"publisher","award":["1R01NR018762"],"award-info":[{"award-number":["1R01NR018762"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain, Behavior, and Immunity"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.bbi.2025.02.003","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T19:44:32Z","timestamp":1738871072000},"page":"144-159","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Longitudinal associations of dietary intake with fatigue in colorectal cancer survivors up to 1\u00a0year post-treatment, and the potential mediating role of the kynurenine pathway"],"prefix":"10.1016","volume":"126","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4352-6198","authenticated-orcid":false,"given":"Dani\u00eblle D.B.","family":"Holthuijsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith J.M.","family":"Rijnhart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martijn J.L.","family":"Bours","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eline H.","family":"van Roekel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per M.","family":"Ueland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phanie O.","family":"Breukink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryska L.G.","family":"Janssen-Heijnen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joop L.","family":"Konsten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric T.P.","family":"Keulen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"McCann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"Brezina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biljana","family":"Gigic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelia M.","family":"Ulrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matty P.","family":"Weijenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone J.P.M.","family":"Eussen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbi.2025.02.003_b0010","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1093\/jnci\/85.5.365","article-title":"The European organization for research and treatment of cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology","volume":"85","author":"Aaronson","year":"1993","journal-title":"JNCI: J. Natl. Cancer Inst."},{"key":"10.1016\/j.bbi.2025.02.003_b0015","doi-asserted-by":"crossref","DOI":"10.1177\/1178646917691938","article-title":"Kynurenine pathway of tryptophan metabolism: regulatory and functional aspects","volume":"10","author":"Badawy","year":"2017","journal-title":"Int. J. Tryptophan Res."},{"key":"10.1016\/j.bbi.2025.02.003_b0020","doi-asserted-by":"crossref","DOI":"10.1177\/1178646919868978","article-title":"The plasma [kynurenine]\/[tryptophan] ratio and indoleamine 2, 3-dioxygenase: time for appraisal","volume":"12","author":"Badawy","year":"2019","journal-title":"Int. J. Tryptophan Res."},{"key":"10.1016\/j.bbi.2025.02.003_b0025","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1017\/S000711451800363X","article-title":"Nutrition therapy for the management of cancer-related fatigue and quality of life: a systematic review and meta-analysis","volume":"122","author":"Baguley","year":"2019","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.bbi.2025.02.003_b0030","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.clnu.2020.05.016","article-title":"Mediterranean-style dietary pattern improves cancer-related fatigue and quality of life in men with prostate cancer treated with androgen deprivation therapy: a pilot randomised control trial","volume":"40","author":"Baguley","year":"2021","journal-title":"Clin. Nutr."},{"key":"10.1016\/j.bbi.2025.02.003_b0035","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2014.00485","article-title":"Tryptophan-catabolizing enzymes\u2013party of three","volume":"5","author":"Ball","year":"2014","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbi.2025.02.003_b0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2458-14-749","article-title":"Which activity monitor to use? Validity, reproducibility and user friendliness of three activity monitors","volume":"14","author":"Berendsen","year":"2014","journal-title":"BMC Public Health"},{"key":"10.1016\/j.bbi.2025.02.003_b0045","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.bbi.2007.03.013","article-title":"Cancer-related fatigue: links with inflammation in cancer patients and survivors","volume":"21","author":"Bower","year":"2007","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbi.2025.02.003_b0050","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/nrclinonc.2014.127","article-title":"Cancer-related fatigue\u2014mechanisms, risk factors, and treatments","volume":"11","author":"Bower","year":"2014","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"10.1016\/j.bbi.2025.02.003_b0055","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1017\/S0007114518000661","article-title":"Colorectal cancers survivors\u2019 adherence to lifestyle recommendations and cross-sectional associations with health-related quality of life","volume":"120","author":"Breedveld-Peters","year":"2018","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.bbi.2025.02.003_b0060","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/jhn.12435","article-title":"Dietary and nutrition interventions for the therapeutic treatment of chronic fatigue syndrome\/myalgic encephalomyelitis: a systematic review","volume":"30","author":"Campagnolo","year":"2017","journal-title":"J. Hum. Nutr. Diet."},{"key":"10.1016\/j.bbi.2025.02.003_b0065","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1136\/bmjspcare-2021-003244","article-title":"Cancer-related fatigue\u2014pharmacological interventions: systematic review and network meta-analysis","volume":"13","author":"Chow","year":"2023","journal-title":"BMJ Support. Palliat. Care"},{"key":"10.1016\/j.bbi.2025.02.003_b0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13643-019-1230-2","article-title":"The effectiveness of psychological interventions for fatigue in cancer survivors: systematic review of randomised controlled trials","volume":"8","author":"Corbett","year":"2019","journal-title":"Syst. Rev."},{"key":"10.1016\/j.bbi.2025.02.003_b0075","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.3390\/nu14071496","article-title":"A molecular approach to understanding the role of diet in cancer-related fatigue: challenges and future opportunities","volume":"14","author":"Crowder","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.bbi.2025.02.003_b0080","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.arcmed.2019.12.015","article-title":"Effects of moderate-to-vigorous physical activity on cancer-related fatigue in patients with colorectal cancer: a systematic review and meta-analysis","volume":"51","author":"Dun","year":"2020","journal-title":"Arch. Med. Res."},{"key":"10.1016\/j.bbi.2025.02.003_b0085","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0227384","article-title":"Metabolic analysis of amino acids and vitamin B6 pathways in lymphoma survivors with cancer related chronic fatigue","volume":"15","author":"Foss\u00e5","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.bbi.2025.02.003_b0090","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/j.1467-9280.2007.01882.x","article-title":"Required sample size to detect the mediated effect","volume":"18","author":"Fritz","year":"2007","journal-title":"Psychol. Sci."},{"key":"10.1016\/j.bbi.2025.02.003_b0095","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2022-062930","article-title":"Cohort profile: Biomarkers related to folate-dependent one-carbon metabolism in colorectal cancer recurrence and survival\u2013the FOCUS Consortium","volume":"12","author":"Gigic","year":"2022","journal-title":"BMJ Open"},{"key":"10.1016\/j.bbi.2025.02.003_b0100","first-page":"156","article-title":"Immunosuppression routed via the kynurenine pathway: a biochemical and pathophysiologic approach","volume":"45","author":"Gonzalez","year":"2008","journal-title":"Adv. Clin. Chem."},{"key":"10.1016\/j.bbi.2025.02.003_b0105","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.nut.2005.06.003","article-title":"Efficacy of l-carnitine administration on fatigue, nutritional status, oxidative stress, and related quality of life in 12 advanced cancer patients undergoing anticancer therapy","volume":"22","author":"Gramignano","year":"2006","journal-title":"Nutrition"},{"key":"10.1016\/j.bbi.2025.02.003_b0110","first-page":"51","article-title":"Diet components associated with perceived fatigue in breast cancer survivors","volume":"22","author":"Guest","year":"2013","journal-title":"Eur. J. Cancer Care"},{"key":"10.1016\/j.bbi.2025.02.003_b0115","doi-asserted-by":"crossref","first-page":"4371","DOI":"10.3390\/nu16244371","article-title":"The mediating role of gut microbiota on the association between dietary quality and cancer-related fatigue among breast cancer patients: a cross-sectional study","volume":"16","author":"He","year":"2024","journal-title":"Nutrients"},{"key":"10.1016\/j.bbi.2025.02.003_b0120","doi-asserted-by":"crossref","unstructured":"Holthuijsen, D.D.B., Bours, M.J.L., van Roekel, E.H., Breukink, S.O., Janssen-Heijnen, M.L.G., Keulen, E.T.P., Ueland, P.M., Midttun, \u00d8., Brezina, S., Gigic, B., Gsur, A., Kok, D.E., Ose, J., Ulrich, C.M., Weijenberg, M.P., Eussen, S.J.P.M., 2022. Longitudinal Associations of Adherence to the Dietary World Cancer Research Fund\/American Institute for Cancer Research (WCRF\/AICR) and Dutch Healthy Diet (DHD) Recommendations with Plasma Kynurenines in Colorectal Cancer Survivors after Treatment. Nutrients 14, 5151.","DOI":"10.3390\/nu14235151"},{"key":"10.1016\/j.bbi.2025.02.003_b0005","unstructured":"Gezondheidsraad (Health Council of the Netherlands), 2015. Dutch dietary guidelines 2015 (Richtlijnen goede voeding 2015), The Hague. Available online: https:\/\/www.gezondheidsraad.nl\/documenten\/adviezen\/2015\/11\/04\/richtlijnen-goede-voeding-2015."},{"issue":"5","key":"10.1016\/j.bbi.2025.02.003_b0125","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/j.ajcnut.2023.08.003","article-title":"Longitudinal associations of macronutrient and micronutrient intake with plasma kynurenines in colorectal cancer survivors up to 12 months posttreatment","volume":"118","author":"Holthuijsen","year":"2023","journal-title":"Am. J. Clin. Nutr."},{"issue":"7","key":"10.1016\/j.bbi.2025.02.003_b0135","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1002\/ijc.34992","article-title":"Longitudinal associations of plasma kynurenines and ratios with fatigue and quality of life in colorectal cancer survivors up to 12 months post\u2010treatment","volume":"155","author":"Holthuijsen","year":"2024","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.bbi.2025.02.003_b0140","first-page":"2165","article-title":"Variation in fatigue among 6011 (long-term) cancer survivors and a normative population: a study from the population-based PROFILES registry","volume":"23","author":"Husson","year":"2015","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.bbi.2025.02.003_b0145","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1080\/01635581.2018.1513046","article-title":"Nutritional interventions for treating cancer-related fatigue: a qualitative review","volume":"71","author":"Inglis","year":"2019","journal-title":"Nutr. Cancer"},{"key":"10.1016\/j.bbi.2025.02.003_b0150","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.3390\/nu13031029","article-title":"Low carb and ketogenic diets increase quality of life, physical performance, body composition, and metabolic health of women with breast cancer","volume":"13","author":"K\u00e4mmerer","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.bbi.2025.02.003_b0155","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1017\/S0007114520003487","article-title":"Associations of the dietary world cancer research fund\/american institute for cancer research (WCRF\/AICR) recommendations with patient-reported outcomes in colorectal cancer survivors 2\u201310 years post-diagnosis: a cross-sectional analysis","volume":"125","author":"Kenkhuis","year":"2021","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.bbi.2025.02.003_b0160","doi-asserted-by":"crossref","first-page":"417","DOI":"10.3390\/cancers14020417","article-title":"Longitudinal associations of adherence to the world cancer research fund\/american institute for cancer research (WCRF\/AICR) lifestyle recommendations with quality of life and symptoms in colorectal cancer survivors up to 24 months post-treatment","volume":"14","author":"Kenkhuis","year":"2022","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.bbi.2025.02.003_b0165","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1093\/ajcn\/nqab360","article-title":"Longitudinal associations of fiber, vegetable, and fruit intake with quality of life and fatigue in colorectal cancer survivors up to 24 months posttreatment","volume":"115","author":"Kenkhuis","year":"2022","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.bbi.2025.02.003_b0170","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1002\/cncr.29302","article-title":"Inflammation\u2010induced activation of the indoleamine 2, 3\u2010dioxygenase pathway: relevance to cancer\u2010related fatigue","volume":"121","author":"Kim","year":"2015","journal-title":"Cancer"},{"key":"10.1016\/j.bbi.2025.02.003_b0175","doi-asserted-by":"crossref","first-page":"4202","DOI":"10.3390\/cancers14174202","article-title":"The effects of a Mediterranean diet intervention on cancer-related fatigue for patients undergoing chemotherapy: a pilot randomized controlled trial","volume":"14","author":"Kleckner","year":"2022","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.bbi.2025.02.003_b0180","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1001\/jamasurg.2021.2311","article-title":"Association of habitual preoperative dietary fiber intake with complications after colorectal cancer surgery","volume":"156","author":"Kok","year":"2021","journal-title":"JAMA Surg."},{"key":"10.1016\/j.bbi.2025.02.003_b0185","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.clnu.2018.12.037","article-title":"Is dietary supplement use longitudinally associated with fatigue in stage I-III colorectal cancer survivors?","volume":"39","author":"Koole","year":"2020","journal-title":"Clin. Nutr."},{"key":"10.1016\/j.bbi.2025.02.003_b0190","doi-asserted-by":"crossref","first-page":"379","DOI":"10.2307\/2983064","article-title":"Spurious correlation and the fallacy of the ratio standard revisited","volume":"156","author":"Kronmal","year":"1993","journal-title":"J. R. Stat. Soc. Ser. A Stat. Soc."},{"key":"10.1016\/j.bbi.2025.02.003_b0195","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0036956","article-title":"Fatigue in patients with lung cancer is related with accelerated tryptophan breakdown","volume":"7","author":"Kurz","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bbi.2025.02.003_b0200","doi-asserted-by":"crossref","first-page":"2908","DOI":"10.1093\/jn\/nxab231","article-title":"Inflammation-related marker profiling of dietary patterns and all-cause mortality in the Melbourne collaborative cohort study","volume":"151","author":"Li","year":"2021","journal-title":"J. Nutr."},{"key":"10.1016\/j.bbi.2025.02.003_b0205","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1111\/codi.16746","article-title":"Trajectories and risk factors of fatigue following colorectal cancer diagnosis","volume":"25","author":"Li","year":"2023","journal-title":"Colorectal Dis."},{"key":"10.1016\/j.bbi.2025.02.003_b0210","doi-asserted-by":"crossref","first-page":"3065","DOI":"10.1080\/10408398.2021.1983768","article-title":"Gut microbiota as a potential target for developing anti-fatigue foods","volume":"63","author":"Li","year":"2023","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.bbi.2025.02.003_b0215","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.pmn.2022.09.002","article-title":"Tryptophan and kynurenine pathway metabolites and psychoneurological symptoms among breast cancer survivors","volume":"24","author":"Li","year":"2023","journal-title":"Pain Manag. Nurs."},{"key":"10.1016\/j.bbi.2025.02.003_b0220","series-title":"Impact of Low Carbohydrate Diet on Self-Report Fatigue and Weakness in Prostate Cancer Patients","first-page":"499","author":"Lin","year":"2021"},{"key":"10.1016\/j.bbi.2025.02.003_b0225","doi-asserted-by":"crossref","DOI":"10.1111\/spc3.12708","article-title":"Improving causal inference of mediation analysis with multiple mediators using interventional indirect effects","volume":"16","author":"Loh","year":"2022","journal-title":"Soc. Pers. Psychol. Compass"},{"key":"10.1016\/j.bbi.2025.02.003_b0230","doi-asserted-by":"crossref","first-page":"2289","DOI":"10.1017\/S136898001700091X","article-title":"Development and evaluation of the Dutch Healthy Diet index 2015","volume":"20","author":"Looman","year":"2017","journal-title":"Public Health Nutr."},{"key":"10.1016\/j.bbi.2025.02.003_b0235","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1093\/ajcn\/nqy026","article-title":"Mediterranean diet and risk of frailty syndrome among women with type 2 diabetes","volume":"107","author":"Lopez-Garcia","year":"2018","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.bbi.2025.02.003_b0240","first-page":"3","article-title":"Overview of the role of vitamins and minerals on the kynurenine pathway in health and disease","volume":"67","author":"Majewski","year":"2016","journal-title":"J. Physiol. Pharmacol."},{"key":"10.1016\/j.bbi.2025.02.003_b0245","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.3390\/nu9111224","article-title":"Efficacy and effectiveness of carnitine supplementation for cancer-related fatigue: a systematic literature review and meta-analysis","volume":"9","author":"Marx","year":"2017","journal-title":"Nutrients"},{"key":"10.1016\/j.bbi.2025.02.003_b0250","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1002\/rcm.4013","article-title":"Quantitative profiling of biomarkers related to B\u2010vitamin status, tryptophan metabolism and inflammation in human plasma by liquid chromatography\/tandem mass spectrometry","volume":"23","author":"Midttun","year":"2009","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.bbi.2025.02.003_b0255","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1007\/s00216-012-6602-6","article-title":"High-throughput, low-volume, multianalyte quantification of plasma metabolites related to one-carbon metabolism using HPLC-MS\/MS","volume":"405","author":"Midttun","year":"2013","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.bbi.2025.02.003_b0260","doi-asserted-by":"crossref","first-page":"916","DOI":"10.4103\/jcrt.JCRT_50_17","article-title":"Cancer-related fatigue treatment: an overview","volume":"13","author":"Mohandas","year":"2017","journal-title":"J. Cancer Res. Ther."},{"key":"10.1016\/j.bbi.2025.02.003_b0265","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.3390\/cells10071603","article-title":"Role of kynurenine pathway in oxidative stress during neurodegenerative disorders","volume":"10","author":"Mor","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.bbi.2025.02.003_b0270","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1001\/jamaoncol.2016.6914","article-title":"Comparison of pharmaceutical, psychological, and exercise treatments for cancer-related fatigue: a meta-analysis","volume":"3","author":"Mustian","year":"2017","journal-title":"JAMA Oncol."},{"key":"10.1016\/j.bbi.2025.02.003_b0275","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1002\/cam4.3766","article-title":"Nutrition intervention is beneficial to the quality of life of patients with gastrointestinal cancer undergoing chemotherapy in Vietnam","volume":"10","author":"Nguyen","year":"2021","journal-title":"Cancer Med."},{"key":"10.1016\/j.bbi.2025.02.003_b0280","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12885-018-4923-3","article-title":"Colorectal cancer survivors: an investigation of symptom burden and influencing factors","volume":"18","author":"O\u2019Gorman","year":"2018","journal-title":"BMC Cancer"},{"key":"10.1016\/j.bbi.2025.02.003_b0285","first-page":"859","article-title":"A pilot phase II trial of magnesium supplements to reduce menopausal hot flashes in breast cancer patients","volume":"19","author":"Park","year":"2011","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.bbi.2025.02.003_b0290","article-title":"Interventions for cancer\u2010related fatigue: a scoping review","volume":"27","author":"Pearson","year":"2018","journal-title":"Eur. J. Cancer Care"},{"key":"10.1016\/j.bbi.2025.02.003_b0295","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.lungcan.2018.07.021","article-title":"EORTC QLQ-C30 summary score reliably detects changes in QoL three months after anatomic lung resection for non-small cell lung cancer (NSCLC)","volume":"123","author":"Pompili","year":"2018","journal-title":"Lung Cancer"},{"key":"10.1016\/j.bbi.2025.02.003_b0300","unstructured":"R Core Team, 2024. R: A Language and Environment for Statistical Computing."},{"key":"10.1016\/j.bbi.2025.02.003_b0305","article-title":"Randomized-controlled trial of a modified Mediterranean dietary program for multiple sclerosis: a pilot study","volume":"36","author":"Sand","year":"2019","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.bbi.2025.02.003_b0310","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/art.10993","article-title":"The self\u2010administered comorbidity questionnaire: a new method to assess comorbidity for clinical and health services research","volume":"49","author":"Sangha","year":"2003","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.bbi.2025.02.003_b0315","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1080\/01635581.2022.2159044","article-title":"Effects of a plant-based high-protein diet on fatigue in breast cancer patients undergoing adjuvant chemotherapy\u2013a randomized controlled trial","volume":"75","author":"Sathiaraj","year":"2023","journal-title":"Nutr. Cancer"},{"key":"10.1016\/j.bbi.2025.02.003_b0320","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/s00432-007-0191-3","article-title":"Diminished quality of life in patients with cancer correlates with tryptophan degradation","volume":"133","author":"Schroecksnadel","year":"2007","journal-title":"J. Cancer Res. Clin. Oncol."},{"key":"10.1016\/j.bbi.2025.02.003_b0325","first-page":"11","article-title":"Fatigue in disease-free cancer patients compared with fatigue in patients with chronic fatigue syndrome","volume":"9","author":"Servaes","year":"2001","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.bbi.2025.02.003_b0330","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.3390\/nu11071572","article-title":"Operationalizing the 2018 world cancer research fund\/american institute for cancer research (WCRF\/AICR) cancer prevention recommendations: a standardized scoring system","volume":"11","author":"Shams-White","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.bbi.2025.02.003_b0335","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1158\/1055-9965.EPI-19-1444","article-title":"Further guidance in implementing the standardized 2018 world cancer research fund\/american institute for cancer research (WCRF\/AICR) scorefurther guidance in implementing the 2018 WCRF\/AICR score","volume":"29","author":"Shams-White","year":"2020","journal-title":"Cancer Epidemiol. Biomark. Prev."},{"issue":"8","key":"10.1016\/j.bbi.2025.02.003_b0340","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1093\/aje\/kwae026","article-title":"Methodological examination of the 2018 World Cancer Research Fund\/American Institute for Cancer Research (WCRF\/AICR) Score","volume":"193","author":"Shams-White","year":"2024","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.bbi.2025.02.003_b0345","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1080\/01635581.2015.1040520","article-title":"Low recent protein intake predicts cancer-related fatigue and increased mortality in patients with advanced tumor disease undergoing chemotherapy","volume":"67","author":"Stob\u00e4us","year":"2015","journal-title":"Nutr. Cancer"},{"key":"10.1016\/j.bbi.2025.02.003_b0350","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1517\/13543784.10.4.633","article-title":"Kynurenic acid antagonists and kynurenine pathway inhibitors","volume":"10","author":"Stone","year":"2001","journal-title":"Expert Opin. Invest. Drugs"},{"key":"10.1016\/j.bbi.2025.02.003_b0355","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1038\/nrd870","article-title":"Endogenous kynurenines as targets for drug discovery and development","volume":"1","author":"Stone","year":"2002","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.bbi.2025.02.003_b0360","first-page":"209","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J. Clin."},{"key":"10.1016\/j.bbi.2025.02.003_b0365","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1016\/S0021-9258(19)77982-4","article-title":"Mechanism of interferon-gamma action. Characterization of indoleamine 2, 3-dioxygenase in cultured human cells induced by interferon-gamma and evaluation of the enzyme-mediated tryptophan degradation in its anticellular activity","volume":"263","author":"Takikawa","year":"1988","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbi.2025.02.003_b0370","doi-asserted-by":"crossref","first-page":"6974","DOI":"10.3390\/ijms22136974","article-title":"A role for xanthurenic acid in the control of brain dopaminergic activity","volume":"22","author":"Taleb","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbi.2025.02.003_b0375","doi-asserted-by":"crossref","first-page":"228","DOI":"10.3390\/nu12010228","article-title":"Vitamins and minerals for energy, fatigue and cognition: a narrative review of the biochemical and clinical evidence","volume":"12","author":"Tardy","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.bbi.2025.02.003_b0380","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/cei.12092","article-title":"A community\u2010based study on determinants of circulating markers of cellular immune activation and kynurenines: the Hordaland Health Study","volume":"173","author":"Theofylaktopoulou","year":"2013","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.bbi.2025.02.003_b0385","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1017\/S0007114514001858","article-title":"Vitamins B2 and B6 as determinants of kynurenines and related markers of interferon-\u03b3-mediated immune activation in the community-based Hordaland Health Study","volume":"112","author":"Theofylaktopoulou","year":"2014","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.bbi.2025.02.003_b0390","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1016\/j.ejca.2013.01.012","article-title":"Quantifying fatigue in (long-term) colorectal cancer survivors: a study from the population-based patient reported outcomes following initial treatment and long term evaluation of survivorship registry","volume":"49","author":"Thong","year":"2013","journal-title":"Eur. J. Cancer"},{"key":"10.1016\/j.bbi.2025.02.003_b0395","doi-asserted-by":"crossref","first-page":"692","DOI":"10.3758\/s13428-011-0076-x","article-title":"RMediation: An R package for mediation analysis confidence intervals","volume":"43","author":"Tofighi","year":"2011","journal-title":"Behav. Res. Methods"},{"key":"10.1016\/j.bbi.2025.02.003_b0400","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1093\/ajcn\/nqab266","article-title":"Adjustment for energy intake in nutritional research: a causal inference perspective","volume":"115","author":"Tomova","year":"2022","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.bbi.2025.02.003_b0405","doi-asserted-by":"crossref","first-page":"934","DOI":"10.3945\/ajcn.113.064998","article-title":"Substrate product ratios of enzymes in the kynurenine pathway measured in plasma as indicators of functional vitamin B-6 status","volume":"98","author":"Ulvik","year":"2013","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.bbi.2025.02.003_b0410","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1093\/ajcn\/nqz228","article-title":"Tryptophan catabolites as metabolic markers of vitamin B-6 status evaluated in cohorts of healthy adults and cardiovascular patients","volume":"111","author":"Ulvik","year":"2020","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.bbi.2025.02.003_b0415","doi-asserted-by":"crossref","first-page":"7616","DOI":"10.1021\/acs.analchem.1c00119","article-title":"Quantifying precision loss in targeted metabolomics based on mass spectrometry and nonmatching internal standards","volume":"93","author":"Ulvik","year":"2021","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bbi.2025.02.003_b0420","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1158\/1055-9965.EPI-13-1144","article-title":"The applicability of the international classification of functioning, disability, and health to study lifestyle and quality of life of colorectal cancer survivors","volume":"23","author":"van Roekel","year":"2014","journal-title":"Cancer Epidemiol. Biomark. Prev."},{"key":"10.1016\/j.bbi.2025.02.003_b0430","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1002\/ijc.34252","article-title":"Longitudinal associations of plasma metabolites with persistent fatigue among colorectal cancer survivors up to 2 years after treatment","volume":"152","author":"van Roekel","year":"2023","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.bbi.2025.02.003_b0435","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/0022-3999(94)90099-X","article-title":"Dimensional assessment of chronic fatigue syndrome","volume":"38","author":"Vercoulen","year":"1994","journal-title":"J. Psychosom. Res."},{"key":"10.1016\/j.bbi.2025.02.003_b0425","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.pmedr.2016.06.022","article-title":"Associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivors","volume":"4","author":"van Roekel","year":"2016","journal-title":"Prev. Med. Rep."},{"key":"10.1016\/j.bbi.2025.02.003_b0440","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1001\/archneur.1996.00550070080014","article-title":"The measurement of fatigue in patients with multiple sclerosis: a multidimensional comparison with patients with chronic fatigue syndrome and healthy subjects","volume":"53","author":"Vercoulen","year":"1996","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.bbi.2025.02.003_b0450","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/S0895-4356(03)00220-8","article-title":"Reproducibility and relative validity of the short questionnaire to assess health-enhancing physical activity","volume":"56","author":"Wendel-Vos","year":"2003","journal-title":"J. Clin. Epidemiol."},{"key":"10.1016\/j.bbi.2025.02.003_b0455","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jpsychores.2017.05.007","article-title":"The assessment of fatigue: psychometric qualities and norms for the Checklist individual strength","volume":"98","author":"Worm-Smeitink","year":"2017","journal-title":"J. Psychosom. Res."},{"key":"10.1016\/j.bbi.2025.02.003_b0460","doi-asserted-by":"crossref","first-page":"314","DOI":"10.3945\/jn.116.241711","article-title":"Increases in plasma tryptophan are inversely associated with incident cardiovascular disease in the Prevencion con Dieta Mediterranea (PREDIMED) Study","volume":"147","author":"Yu","year":"2017","journal-title":"J. Nutr."},{"key":"10.1016\/j.bbi.2025.02.003_b0465","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.seizure.2019.05.006","article-title":"Changes in tryptophan and kynurenine pathway metabolites in the blood of children treated with ketogenic diet for refractory epilepsy","volume":"69","author":"\u017barnowska","year":"2019","journal-title":"Seizure"},{"key":"10.1016\/j.bbi.2025.02.003_b0470","doi-asserted-by":"crossref","DOI":"10.1016\/j.medmic.2022.100070","article-title":"The gut microbiome: linking dietary fiber to inflammatory diseases","volume":"14","author":"Zhang","year":"2022","journal-title":"Med. Microecol."},{"key":"10.1016\/j.bbi.2025.02.003_b0475","first-page":"153","article-title":"Effectiveness of exercise interventions in the management of cancer-related fatigue: a systematic review of systematic reviews","volume":"31","author":"Zhang","year":"2023","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.bbi.2025.02.003_b0480","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s10549-016-4070-y","article-title":"Fatigue reduction diet in breast cancer survivors: a pilot randomized clinical trial","volume":"161","author":"Zick","year":"2017","journal-title":"Breast Cancer Res. Treat."},{"key":"10.1016\/j.bbi.2025.02.003_b0445","unstructured":"World Cancer Research Fund\/American Institute for Cancer Research, 2018. Diet, Nutrition, Physical Activity and Cancer: A Global Perspective - Continuous Update Project Export Report 2018.Available online: https:\/\/www.wcrf.org\/dietandcancer."}],"container-title":["Brain, Behavior, and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159125000443?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159125000443?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T03:51:48Z","timestamp":1777348308000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889159125000443"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":95,"alternative-id":["S0889159125000443"],"URL":"https:\/\/doi.org\/10.1016\/j.bbi.2025.02.003","relation":{},"ISSN":["0889-1591"],"issn-type":[{"value":"0889-1591","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Longitudinal associations of dietary intake with fatigue in colorectal cancer survivors up to 1\u00a0year post-treatment, and the potential mediating role of the kynurenine pathway","name":"articletitle","label":"Article Title"},{"value":"Brain, Behavior, and Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbi.2025.02.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}