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Physiol."},{"issue":"1","key":"10.1016\/j.bbi.2025.03.022_b0460","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1186\/s40478-019-0829-9","article-title":"Region-specific interneuron demyelination and heightened anxiety-like behavior induced by adolescent binge alcohol treatment","volume":"7","author":"Rice","year":"2019","journal-title":"Acta Neuropathologica Communications"},{"issue":"123","key":"10.1016\/j.bbi.2025.03.022_b0465","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1152\/japplphysiol.00856.2016","article-title":"Automated full-range pressure-volume curves in mice and rats","volume":"1985","author":"Robichaud","year":"2017","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.bbi.2025.03.022_b0470","doi-asserted-by":"crossref","unstructured":"Rodrigues, D.H., Vilela, M. de C., Lacerda-Queiroz, N., Miranda, A.S. de, Sousa, L.F. da C., Reis, H.J. dos, Teixeira, A.L., 2011. Behavioral investigation of mice with experimental autoimmune encephalomyelitis. Arq. Neuropsiquiatr. 69, 938\u2013942. doi: 10.1590\/S0004-282X2011000700018.","DOI":"10.1590\/S0004-282X2011000700018"},{"key":"10.1016\/j.bbi.2025.03.022_b0475","article-title":"Post-COVID-19 syndrome: Descriptive analysis based on a survivors\u2019 cohort in Colombia","volume":"6","author":"Romero","year":"2023","journal-title":"Glob Epidemiol"},{"key":"10.1016\/j.bbi.2025.03.022_b0480","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuint.2023.105567","article-title":"Neuromuscular defects after infection with a beta coronavirus in mice","volume":"169","author":"Rossi","year":"2023","journal-title":"Neurochem. 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Rev."},{"key":"10.1016\/j.bbi.2025.03.022_b0565","doi-asserted-by":"crossref","unstructured":"Takahashi, T., Ellingson, M.K., Wong, P., Israelow, B., Lucas, C., Klein, J., Silva, J., Mao, T., Oh, J.E., Tokuyama, M., Lu, P., Venkataraman, A., Park, A., Liu, F., Meir, A., Sun, J., Wang, E.Y., Casanovas-Massana, A., Wyllie, A.L., Vogels, C.B.F., Earnest, R., Lapidus, S., Ott, I.M., Moore, A.J., Anastasio, K., Askenase, M.H., Batsu, M., Beatty, H., Bermejo, S., Bickerton, S., Brower, K., Bucklin, M.L., Cahill, S., Campbell, M., Cao, Y., Courchaine, E., Datta, R., DeIuliis, G., Geng, B., Glick, L., Handoko, R., Kalinich, C., Khoury-Hanold, W., Kim, D., Knaggs, L., Kuang, M., Kudo, E., Lim, J., Linehan, M., Lu-Culligan, A., Malik, A.A., Martin, A., Matos, I., McDonald, D., Minasyan, M., Mohanty, S., Muenker, M.C., Naushad, N., Nelson, A., Nouws, J., Nunez-Smith, M., Obaid, A., Ott, I., Park, H.J., Peng, X., Petrone, M., Prophet, S., Rahming, H., Rice, T., Rose, K.A., Sewanan, L., Sharma, L., Shepard, D., Silva, E., Simonov, M., Smolgovsky, M., Song, E., Sonnert, N., Strong, Y., Todeasa, C., Valdez, J., Velazquez, S., Vijayakumar, P., Wang, H., Watkins, A., White, E.B., Yang, Y., Shaw, A., Fournier, J.B., Odio, C.D., Farhadian, S., Dela Cruz, C., Grubaugh, N.D., Schulz, W.L., Ring, A.M., Ko, A.I., Omer, S.B., Iwasaki, A., 2020. Sex differences in immune responses that underlie COVID-19 disease outcomes. Nature 2020 588:7837 588, 315\u2013320. doi: 10.1038\/s41586-020-2700-3.","DOI":"10.1038\/s41586-020-2700-3"},{"key":"10.1016\/j.bbi.2025.03.022_b0570","doi-asserted-by":"crossref","first-page":"3663","DOI":"10.1007\/s10238-023-01057-6","article-title":"Five cluster classifications of long COVID and their background factors: a cross-sectional study in Japan","volume":"23","author":"Tsuchida","year":"2023","journal-title":"Clin. Exp. Med."},{"key":"10.1016\/j.bbi.2025.03.022_b0575","doi-asserted-by":"crossref","unstructured":"Vandenbark, A.A., Offner, H., Matejuk, S., Matejuk, A., 2021. Microglia and astrocyte involvement in neurodegeneration and brain cancer. 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