{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T16:44:35Z","timestamp":1788281075132,"version":"build-2803163510"},"reference-count":88,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T00:00:00Z","timestamp":1754870400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Forschung, Technologie und Raumfahrt","doi-asserted-by":"publisher","award":["01GM1908A"],"award-info":[{"award-number":["01GM1908A"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Forschung, Technologie und Raumfahrt","doi-asserted-by":"publisher","award":["01GM1908C"],"award-info":[{"award-number":["01GM1908C"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Forschung, Technologie und Raumfahrt","doi-asserted-by":"publisher","award":["01GM2208C"],"award-info":[{"award-number":["01GM2208C"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Forschung, Technologie und Raumfahrt","doi-asserted-by":"publisher","award":["01GM1908D"],"award-info":[{"award-number":["01GM1908D"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Forschung, Technologie und Raumfahrt","doi-asserted-by":"publisher","award":["01GM2208A"],"award-info":[{"award-number":["01GM2208A"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Forschung, Technologie und Raumfahrt","doi-asserted-by":"publisher","award":["16GW0279K"],"award-info":[{"award-number":["16GW0279K"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100023719","name":"German-American Fulbright Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100023719","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001656","name":"Helmholtz-Gemeinschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001656","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017268","name":"Berlin Institute of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100017268","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009318","name":"Helmholtz Association","doi-asserted-by":"publisher","award":["HIL -A03"],"award-info":[{"award-number":["HIL -A03"]}],"id":[{"id":"10.13039\/501100009318","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 GM136724"],"award-info":[{"award-number":["R01 GM136724"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 NS110112"],"award-info":[{"award-number":["R01 NS110112"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 NS123712"],"award-info":[{"award-number":["R01 NS123712"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain, Behavior, and Immunity"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.bbi.2025.106073","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T23:20:54Z","timestamp":1754954454000},"page":"106073","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Specific viral antibodies associate with anti-NMDAR encephalitis after herpes simplex encephalitis"],"prefix":"10.1016","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2913-1015","authenticated-orcid":false,"given":"Jakob","family":"Kreye","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William R.","family":"Morgenlander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manjusha","family":"Thakar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poul M.","family":"Schulte-Frankenfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Schott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"B\u00fcnger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Christian","family":"Kornau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia W.","family":"Angkeow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahana","family":"Jayaraman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolin","family":"Otto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wiebke","family":"Hahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Lewerenz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franziska S.","family":"Thaler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirjam","family":"Korporal-Kuhnke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nico","family":"Melzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justina","family":"Dargvainiene","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian G.","family":"Bien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rose","family":"Kohlie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Lattwein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dietmar","family":"Schmitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter A.","family":"Calabresi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos A.","family":"Pardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harald","family":"Pr\u00fcss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klemens","family":"Ruprecht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Benjamin Larman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbi.2025.106073_b0005","first-page":"1007","article-title":"Statistical power analysis for the behavioral-sciences - cohen","volume":"67","author":"Statistical Power Analysis for the Behavioral-Sciences","year":"1988","journal-title":"J. Percept Motor Skill"},{"key":"10.1016\/j.bbi.2025.106073_b0010","series-title":"Herpes Simplex Encephalitis","author":"Ak","year":"2024"},{"key":"10.1016\/j.bbi.2025.106073_b0015","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1056\/NEJMoa066092","article-title":"Duration of humoral immunity to common viral and vaccine antigens","volume":"357","author":"Amanna","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.bbi.2025.106073_b0020","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1136\/jnnp.57.8.897","article-title":"Cerebrospinal fluid in the diagnosis of multiple sclerosis: a consensus report","volume":"57","author":"Andersson","year":"1994","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"1051\u20131066","key":"10.1016\/j.bbi.2025.106073_b0025","first-page":"e1054","article-title":"Phage display of environmental protein toxins and virulence factors reveals the prevalence, persistence, and genetics of antibody responses","volume":"55","author":"Angkeow","year":"2022","journal-title":"Immunity"},{"key":"10.1016\/j.bbi.2025.106073_b0030","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1212\/WNL.0000000000002125","article-title":"Autoimmune post-herpes simplex encephalitis of adults and teenagers","volume":"85","author":"Armangue","year":"2015","journal-title":"Neurology"},{"key":"10.1016\/j.bbi.2025.106073_b0035","doi-asserted-by":"crossref","first-page":"4306","DOI":"10.1093\/brain\/awad238","article-title":"Neurologic complications in herpes simplex encephalitis: clinical, immunological and genetic studies","volume":"146","author":"Armangue","year":"2023","journal-title":"Brain"},{"key":"10.1016\/j.bbi.2025.106073_b0040","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/S1474-4422(18)30244-8","article-title":"Frequency, symptoms, risk factors, and outcomes of autoimmune encephalitis after herpes simplex encephalitis: a prospective observational study and retrospective analysis","volume":"17","author":"Armangue","year":"2018","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0045","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1128\/JCM.37.5.1632-1633.1999","article-title":"Ability of a rapid serology test to detect seroconversion to herpes simplex virus type 2 glycoprotein G soon after infection","volume":"37","author":"Ashley","year":"1999","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.bbi.2025.106073_b0050","first-page":"28","article-title":"Fitting a mixture model by expectation maximization to discover motifs in biopolymers","volume":"2","author":"Bailey","year":"1994","journal-title":"Proc. Int. Conf. Intell. Syst. Mol. Biol."},{"key":"10.1016\/j.bbi.2025.106073_b0055","doi-asserted-by":"crossref","first-page":"W39","DOI":"10.1093\/nar\/gkv416","article-title":"The MEME Suite","volume":"43","author":"Bailey","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbi.2025.106073_b0060","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1093\/infdis\/jit458","article-title":"Seroprevalence of herpes simplex virus types 1 and 2\u2013United States, 1999\u20132010","volume":"209","author":"Bradley","year":"2014","journal-title":"J. Infect Dis."},{"key":"10.1016\/j.bbi.2025.106073_b0065","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1007\/s13311-016-0433-7","article-title":"Herpes simplex virus-1 encephalitis in adults: pathophysiology, diagnosis, and management","volume":"13","author":"Bradshaw","year":"2016","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.bbi.2025.106073_b0070","article-title":"Synapsin autoantibodies during pregnancy are associated with fetal abnormalities","volume":"33","author":"Bunger","year":"2023","journal-title":"Brain Behav. Immun. Health"},{"key":"10.1016\/j.bbi.2025.106073_b0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.113166","article-title":"Human NMDAR autoantibodies disrupt excitatory-inhibitory balance, leading to hippocampal network hypersynchrony","volume":"42","author":"Ceanga","year":"2023","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbi.2025.106073_b0080","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.01446-19","article-title":"Comprehensive mutagenesis of herpes simplex virus 1 genome identifies UL42 as an inhibitor of type I interferon induction","volume":"93","author":"Chapon","year":"2019","journal-title":"J. Virol."},{"key":"10.1016\/j.bbi.2025.106073_b0085","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0214151","article-title":"Characterizing herpes simplex virus type 1 and type 2 seroprevalence declines and epidemiological association in the United States","volume":"14","author":"Chemaitelly","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.bbi.2025.106073_b0090","doi-asserted-by":"crossref","first-page":"e1280","DOI":"10.1212\/WNL.0000000000207664","article-title":"Association of very early treatment initiation with the risk of long-term disability in patients with a first demyelinating event","volume":"101","author":"Cobo-Calvo","year":"2023","journal-title":"Neurology"},{"key":"10.1016\/j.bbi.2025.106073_b0095","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1002\/ana.24189","article-title":"Seroprevalence of autoantibodies against brain antigens in health and disease","volume":"76","author":"Dahm","year":"2014","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0100","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/S1474-4422(19)30244-3","article-title":"An update on anti-NMDA receptor encephalitis for neurologists and psychiatrists: mechanisms and models","volume":"18","author":"Dalmau","year":"2019","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0105","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/S1474-4422(08)70224-2","article-title":"Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies","volume":"7","author":"Dalmau","year":"2008","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0110","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1056\/NEJMra1708712","article-title":"Antibody-mediated encephalitis","volume":"378","author":"Dalmau","year":"2018","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.bbi.2025.106073_b0115","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1002\/ana.21050","article-title":"Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma","volume":"61","author":"Dalmau","year":"2007","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0120","doi-asserted-by":"crossref","first-page":"e643","DOI":"10.1097\/CCM.0000000000005485","article-title":"Herpes simplex virus encephalitis with initial negative polymerase chain reaction in the cerebrospinal fluid: prevalence, associated factors, and clinical impact","volume":"50","author":"de Montmollin","year":"2022","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.bbi.2025.106073_b0125","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1128\/JCM.01900-07","article-title":"Comparison of immunoblotting, calculation of the Goldmann-Witmer coefficient, and real-time PCR using aqueous humor samples for diagnosis of ocular toxoplasmosis","volume":"46","author":"Fekkar","year":"2008","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.bbi.2025.106073_b0130","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1177\/2472555219897567","article-title":"New advances in cell microarray technology to expand applications in target deconvolution and off-target screening","volume":"25","author":"Freeth","year":"2020","journal-title":"SLAS Discov"},{"key":"10.1016\/j.bbi.2025.106073_b0135","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0104169","article-title":"Encephalitis hospitalization rates and inpatient mortality in the United States, 2000-2010","volume":"9","author":"George","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.bbi.2025.106073_b0140","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S1474-4422(15)00401-9","article-title":"A clinical approach to diagnosis of autoimmune encephalitis","volume":"15","author":"Graus","year":"2016","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0145","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1136\/ard.2010.148502","article-title":"Autoantibodies as biomarkers for the prediction of neuropsychiatric events in systemic lupus erythematosus","volume":"70","author":"Hanly","year":"2011","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.bbi.2025.106073_b0150","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1001\/jamaneurol.2013.585","article-title":"Persistent intrathecal antibody synthesis 15 years after recovering from anti-N-methyl-D-aspartate receptor encephalitis","volume":"70","author":"Hansen","year":"2013","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0155","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1001\/jamaneurol.2018.4905","article-title":"Clinical outcomes of escalation vs early intensive disease-modifying therapy in patients with multiple sclerosis","volume":"76","author":"Harding","year":"2019","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0160","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S1474-4422(20)30067-3","article-title":"Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study","volume":"19","author":"He","year":"2020","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0165","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1086\/521262","article-title":"Herpes simplex encephalitis in Sweden, 1990-2001: incidence, morbidity, and mortality","volume":"45","author":"Hjalmarsson","year":"2007","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.bbi.2025.106073_b0170","doi-asserted-by":"crossref","first-page":"5866","DOI":"10.1523\/JNEUROSCI.0167-10.2010","article-title":"Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis","volume":"30","author":"Hughes","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2025.106073_b0175","doi-asserted-by":"crossref","first-page":"12696","DOI":"10.1038\/s41598-023-38462-6","article-title":"The relevance of NMDA receptor antibody-specific index for diagnosis and prognosis in patients with anti-NMDA receptor encephalitis","volume":"13","author":"Hummert","year":"2023","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbi.2025.106073_b0180","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1038\/s44319-024-00056-2","article-title":"Converging synaptic and network dysfunctions in distinct autoimmune encephalitis","volume":"25","author":"Hunter","year":"2024","journal-title":"EMBO Rep."},{"key":"10.1016\/j.bbi.2025.106073_b0185","doi-asserted-by":"crossref","first-page":"315","DOI":"10.2471\/BLT.19.237149","article-title":"Herpes simplex virus: global infection prevalence and incidence estimates, 2016","volume":"98","author":"James","year":"2020","journal-title":"Bull. World Health Organ."},{"issue":"O111","key":"10.1016\/j.bbi.2025.106073_b0190","article-title":"Rapid identification of monospecific monoclonal antibodies using a human proteome microarray","volume":"11","author":"Jeong","year":"2012","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.bbi.2025.106073_b0195","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1002\/ana.25588","article-title":"Chronic dengue virus panencephalitis in a patient with progressive dementia with extrapyramidal features","volume":"86","author":"Johnson","year":"2019","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0200","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1186\/s13054-015-1046-y","article-title":"Long-term outcome of severe herpes simplex encephalitis: a population-based observational study","volume":"19","author":"Jouan","year":"2015","journal-title":"Crit. Care"},{"key":"10.1016\/j.bbi.2025.106073_b0205","doi-asserted-by":"crossref","first-page":"2641","DOI":"10.1093\/brain\/aww208","article-title":"Human cerebrospinal fluid monoclonal N-methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis","volume":"139","author":"Kreye","year":"2016","journal-title":"Brain"},{"key":"10.1016\/j.bbi.2025.106073_b0210","article-title":"Encephalitis patient-derived monoclonal GABAA receptor antibodies cause epileptic seizures","volume":"218","author":"Kreye","year":"2021","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.bbi.2025.106073_b0215","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaut.2013.01.013","article-title":"PhIP-Seq characterization of autoantibodies from patients with multiple sclerosis, type 1 diabetes and rheumatoid arthritis","volume":"43","author":"Larman","year":"2013","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.bbi.2025.106073_b0220","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1038\/nbt.1856","article-title":"Autoantigen discovery with a synthetic human peptidome","volume":"29","author":"Larman","year":"2011","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.bbi.2025.106073_b0225","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S1074-7613(01)00126-1","article-title":"Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo","volume":"14","author":"Le Bon","year":"2001","journal-title":"Immunity"},{"key":"10.1016\/j.bbi.2025.106073_b0230","first-page":"171","article-title":"Counteraction of interferon-induced antiviral responses by herpes simplex viruses","volume":"269","author":"Leib","year":"2002","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"10.1016\/j.bbi.2025.106073_b0235","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1001\/jamaneurol.2014.2956","article-title":"Investigations on CXCL13 in anti-N-methyl-D-aspartate receptor encephalitis: a potential biomarker of treatment response","volume":"72","author":"Leypoldt","year":"2015","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0240","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1038\/s41467-024-45601-8","article-title":"Efficient encoding of large antigenic spaces by epitope prioritization with Dolphyn","volume":"15","author":"Liebhoff","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbi.2025.106073_b0245","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1038\/s41564-019-0421-x","article-title":"Decoding type I and III interferon signalling during viral infection","volume":"4","author":"Mesev","year":"2019","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.bbi.2025.106073_b0250","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1038\/s41596-018-0025-6","article-title":"PhIP-Seq characterization of serum antibodies using oligonucleotide-encoded peptidomes","volume":"13","author":"Mohan","year":"2018","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.bbi.2025.106073_b0255","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1038\/s41467-020-20622-1","article-title":"Profiling serum antibodies with a pan allergen phage library identifies key wheat allergy epitopes","volume":"12","author":"Monaco","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbi.2025.106073_b0260","article-title":"ARscore","author":"Morgenlander","year":"2022","journal-title":"GitHub"},{"key":"10.1016\/j.bbi.2025.106073_b0265","doi-asserted-by":"crossref","first-page":"5833","DOI":"10.1038\/s41467-024-49461-0","article-title":"Precision arbovirus serology with a pan-arbovirus peptidome","volume":"15","author":"Morgenlander","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbi.2025.106073_b0270","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1001\/jamaneurol.2021.3188","article-title":"Use and safety of immunotherapeutic management of N-Methyl-d-aspartate receptor antibody encephalitis: a meta-analysis","volume":"78","author":"Nosadini","year":"2021","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0275","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1111\/dmcn.13448","article-title":"Herpes simplex virus-induced anti-N-methyl-d-aspartate receptor encephalitis: a systematic literature review with analysis of 43 cases","volume":"59","author":"Nosadini","year":"2017","journal-title":"Dev. Med. Child Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0280","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1089\/jir.2011.0028","article-title":"The role of nuclear factor kappaB in the interferon response","volume":"31","author":"Pfeffer","year":"2011","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.bbi.2025.106073_b0285","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1136\/annrheumdis-2019-216599","article-title":"Machine learning algorithms reveal unique gene expression profiles in muscle biopsies from patients with different types of myositis","volume":"79","author":"Pinal-Fernandez","year":"2020","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.bbi.2025.106073_b0290","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1136\/ard-2024-225773","article-title":"Pathological autoantibody internalisation in myositis","volume":"83","author":"Pinal-Fernandez","year":"2024","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.bbi.2025.106073_b0295","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1093\/brain\/awu310","article-title":"Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice","volume":"138","author":"Planaguma","year":"2015","journal-title":"Brain"},{"key":"10.1016\/j.bbi.2025.106073_b0300","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1038\/s41577-021-00543-w","article-title":"Autoantibodies in neurological disease","volume":"21","author":"Pruss","year":"2021","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bbi.2025.106073_b0305","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1002\/ana.23689","article-title":"N-methyl-D-aspartate receptor antibodies in herpes simplex encephalitis","volume":"72","author":"Pruss","year":"2012","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0310","first-page":"99","article-title":"Cerebrospinal fluid\u2013physiology, analysis and interpretation of protein patterns for diagnosis of neurological diseases","volume":"4","author":"Reiber","year":"1998","journal-title":"Mult. Scler."},{"key":"10.1016\/j.bbi.2025.106073_b0315","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/0009-8981(87)90250-6","article-title":"Protein transfer at the blood cerebrospinal fluid barrier and the quantitation of the humoral immune response within the central nervous system","volume":"163","author":"Reiber","year":"1987","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.bbi.2025.106073_b0320","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1093\/clinchem\/37.7.1153","article-title":"Quantification of virus-specific antibodies in cerebrospinal fluid and serum: sensitive and specific detection of antibody synthesis in brain","volume":"37","author":"Reiber","year":"1991","journal-title":"Clin. Chem."},{"key":"10.1016\/j.bbi.2025.106073_b0325","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1038\/s41419-019-2106-z","article-title":"Autoantibodies to synapsin I sequestrate synapsin I and alter synaptic function","volume":"10","author":"Rocchi","year":"2019","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.bbi.2025.106073_b0330","doi-asserted-by":"crossref","first-page":"25540","DOI":"10.1038\/s41598-024-76969-8","article-title":"Intrathecal IgG and IgM synthesis correlates with neurodegeneration markers and corresponds to meningeal B cell presence in MS","volume":"14","author":"Rodriguez-Mogeda","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbi.2025.106073_b0335","doi-asserted-by":"crossref","first-page":"e458","DOI":"10.1212\/NXI.0000000000000458","article-title":"Anti-NMDA receptor encephalitis and nonencephalitic HSV-1 infection","volume":"5","author":"Salovin","year":"2018","journal-title":"Neurol. Neuroimmunol. Neuroinflamm."},{"key":"10.1016\/j.bbi.2025.106073_b0340","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1016\/j.cmi.2021.03.015","article-title":"The role of antibody indexes in clinical virology","volume":"27","author":"Shamier","year":"2021","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.bbi.2025.106073_b0345","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.jcv.2014.03.010","article-title":"Herpes simplex virus encephalitis: clinical manifestations, diagnosis and outcome in 106 adult patients","volume":"60","author":"Sili","year":"2014","journal-title":"J. Clin. Virol."},{"key":"10.1016\/j.bbi.2025.106073_b0350","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s00415-015-7960-8","article-title":"Predictors of outcome in HSV encephalitis","volume":"263","author":"Singh","year":"2016","journal-title":"J. Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0355","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.nbt.2015.09.002","article-title":"Exploration of high-density protein microarrays for antibody validation and autoimmunity profiling","volume":"33","author":"Sjoberg","year":"2016","journal-title":"N. Biotechnol."},{"key":"10.1016\/j.bbi.2025.106073_b0360","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1017\/S0950268811000483","article-title":"Herpes simplex encephalitis and management of acyclovir in encephalitis patients in France","volume":"140","author":"Stahl","year":"2012","journal-title":"Epidemiol. Infect."},{"key":"10.1016\/j.bbi.2025.106073_b0365","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1097\/WCO.0b013e328346be6f","article-title":"Herpes simplex virus encephalitis: new infection or reactivation?","volume":"24","author":"Steiner","year":"2011","journal-title":"Curr. Opin. Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0370","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S1474-4422(17)30470-2","article-title":"Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria","volume":"17","author":"Thompson","year":"2018","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0375","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S1474-4422(12)70310-1","article-title":"Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study","volume":"12","author":"Titulaer","year":"2013","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0380","doi-asserted-by":"crossref","first-page":"E4990","DOI":"10.1073\/pnas.1716788115","article-title":"Isolation of state-dependent monoclonal antibodies against the 12-transmembrane domain glucose transporter 4 using virus-like particles","volume":"115","author":"Tucker","year":"2018","journal-title":"PNAS"},{"key":"10.1016\/j.bbi.2025.106073_b0385","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/S0140-6736(18)32526-1","article-title":"Acute encephalitis in immunocompetent adults","volume":"393","author":"Venkatesan","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.bbi.2025.106073_b0390","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1038\/s41591-021-01409-3","article-title":"Population-wide diversity and stability of serum antibody epitope repertoires against human microbiota","volume":"27","author":"Vogl","year":"2021","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbi.2025.106073_b0395","article-title":"High-throughput identification of autoantibodies that target the human exoproteome","volume":"2","author":"Wang","year":"2022","journal-title":"Cell Rep. Methods"},{"key":"10.1016\/j.bbi.2025.106073_b0400","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1002\/ana.24153","article-title":"Cerebrospinal fluid JC virus antibody index for diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy","volume":"76","author":"Warnke","year":"2014","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.bbi.2025.106073_b0405","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2020-041808","article-title":"Protocol for DexEnceph: a randomised controlled trial of dexamethasone therapy in adults with herpes simplex virus encephalitis","volume":"11","author":"Whitfield","year":"2021","journal-title":"BMJ Open"},{"key":"10.1016\/j.bbi.2025.106073_b0410","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1038\/s42003-021-02635-8","article-title":"Multimodal electrophysiological analyses reveal that reduced synaptic excitatory neurotransmission underlies seizures in a model of NMDAR antibody-mediated encephalitis","volume":"4","author":"Wright","year":"2021","journal-title":"Commun. Biol."},{"key":"10.1016\/j.bbi.2025.106073_b0415","doi-asserted-by":"crossref","first-page":"9788","DOI":"10.1128\/JVI.01440-13","article-title":"Herpes simplex virus 1-encoded tegument protein VP16 abrogates the production of beta interferon (IFN) by inhibiting NF-kappaB activation and blocking IFN regulatory factor 3 to recruit its coactivator CBP","volume":"87","author":"Xing","year":"2013","journal-title":"J. Virol."},{"key":"10.1016\/j.bbi.2025.106073_b0420","doi-asserted-by":"crossref","DOI":"10.1126\/science.aaa0698","article-title":"Viral immunology. Comprehensive serological profiling of human populations using a synthetic human virome","volume":"348","author":"Xu","year":"2015","journal-title":"Science"},{"key":"10.1016\/j.bbi.2025.106073_b0425","doi-asserted-by":"crossref","first-page":"E7526","DOI":"10.1073\/pnas.1615990113","article-title":"Systematic autoantigen analysis identifies a distinct subtype of scleroderma with coincident cancer","volume":"113","author":"Xu","year":"2016","journal-title":"PNAS"},{"key":"10.1016\/j.bbi.2025.106073_b0430","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s00430-013-0295-0","article-title":"Herpes simplex virus 1 DNA polymerase processivity factor UL42 inhibits TNF-alpha-induced NF-kappaB activation by interacting with p65\/RelA and p50\/NF-kappaB1","volume":"202","author":"Zhang","year":"2013","journal-title":"Med. Microbiol. Immunol."},{"key":"10.1016\/j.bbi.2025.106073_b0435","doi-asserted-by":"crossref","first-page":"952","DOI":"10.2340\/00015555-2127","article-title":"Serum reactivity against herpes simplex virus type 1 UL48 protein in Behcet's disease patients and a Behcet's disease-like mouse model","volume":"95","author":"Zheng","year":"2015","journal-title":"Acta Derm. Venereol."},{"key":"10.1016\/j.bbi.2025.106073_bib436","doi-asserted-by":"crossref","unstructured":"Jayaraman, S, Tiniakou, E., Morgenlander, W.R., Na, M., Christopher-Stine, L., Larman, H.B., 2025. Comprehensive Enteroviral Serology Links Infection and Anti-Melanoma Differentiation-Associated Protein 5 Dermatomyositis. ACR Open Rheumatol. 2025 Jan;7(1):e11752. doi: 10.1002\/acr2.11752.","DOI":"10.1002\/acr2.11752"}],"container-title":["Brain, Behavior, and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159125003083?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159125003083?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T12:28:51Z","timestamp":1778761731000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889159125003083"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":88,"alternative-id":["S0889159125003083"],"URL":"https:\/\/doi.org\/10.1016\/j.bbi.2025.106073","relation":{},"ISSN":["0889-1591"],"issn-type":[{"value":"0889-1591","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Specific viral antibodies associate with anti-NMDAR encephalitis after herpes simplex encephalitis","name":"articletitle","label":"Article Title"},{"value":"Brain, Behavior, and Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbi.2025.106073","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"106073"}}