{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T23:49:23Z","timestamp":1792021763795,"version":"4.4.0"},"reference-count":79,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100022720","name":"Fondazione Regionale per la Ricerca Biomedica","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022720","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021856","name":"Ministero dell'Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","award":["PRIN 2017AY8BP4"],"award-info":[{"award-number":["PRIN 2017AY8BP4"]}],"id":[{"id":"10.13039\/501100021856","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021856","name":"Ministero dell'Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","award":["PRIN 202277LAA7"],"award-info":[{"award-number":["PRIN 202277LAA7"]}],"id":[{"id":"10.13039\/501100021856","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021856","name":"Ministero dell'Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","award":["ARS01_01226"],"award-info":[{"award-number":["ARS01_01226"]}],"id":[{"id":"10.13039\/501100021856","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain, Behavior, and Immunity"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.bbi.2025.106077","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T15:38:28Z","timestamp":1755013108000},"page":"106077","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Transcriptional imprints of prenatal stress: sex- and time-specific signatures in early neurodevelopment"],"prefix":"10.1016","volume":"130","author":[{"given":"Maria Grazia","family":"Di Benedetto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moira","family":"Marizzoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Saleri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Bottanelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronica","family":"Begni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerstin","family":"Creutzberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco Andrea","family":"Riva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annamaria","family":"Cattaneo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbi.2025.106077_b0005","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.neulet.2009.12.046","article-title":"Prenatal stress alters presynaptic marker proteins in the hippocampus of rat pups","volume":"470","author":"Afadlal","year":"2010","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.bbi.2025.106077_b0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2021.101195","article-title":"Role of NAD+ in regulating cellular and metabolic signaling pathways","volume":"49","author":"Amjad","year":"2021","journal-title":"Mol. Metab."},{"key":"10.1016\/j.bbi.2025.106077_b0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2017.04.022","article-title":"Linking the biological underpinnings of depression: Role of mitochondria interactions with melatonin, inflammation, sirtuins, tryptophan catabolites, DNA repair and oxidative and nitrosative stress, with consequences for classification and cognition","author":"Anderson","year":"2018","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2025.106077_b0020","first-page":"724","article-title":"Prenatal stress increased \u03b32 GABAA receptor subunit gene expression in hippocampus and potentiated pentylenetetrazol-induced seizure in rats","volume":"23","author":"Bagheri","year":"2020","journal-title":"Iran. J. Basic Med. Sci."},{"key":"10.1016\/j.bbi.2025.106077_b0025","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0027549","article-title":"Prenatal stress induces long-term effects in cell turnover in the hippocampus-hypothalamus-pituitary axis in adult male rats","volume":"6","author":"Baquedano","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.bbi.2025.106077_b0030","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.ynstr.2017.05.001","article-title":"Circuit and synaptic mechanisms of repeated stress: Perspectives from differing contexts, duration, and development","volume":"7","author":"Bath","year":"2017","journal-title":"Neurobiol. Stress"},{"key":"10.1016\/j.bbi.2025.106077_b0035","doi-asserted-by":"crossref","first-page":"2326","DOI":"10.1111\/ejn.15181","article-title":"High-fat diet during adulthood interacts with prenatal stress, affecting both brain inflammatory and neuroendocrine markers in male rats","volume":"55","author":"Berry","year":"2022","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.bbi.2025.106077_b0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.peptides.2021.170550","article-title":"Relaxin increased blood pressure and sympathetic activity in paraventricular nucleus of hypertensive rats via enhancing oxidative stress","volume":"141","author":"Bian","year":"2021","journal-title":"Peptides (n.y.)"},{"key":"10.1016\/j.bbi.2025.106077_b0045","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.tox.2017.07.013","article-title":"Mitochondria targeting by environmental stressors: Implications for redox cellular signaling","volume":"391","author":"Blajszczak","year":"2017","journal-title":"Toxicology"},{"key":"10.1016\/j.bbi.2025.106077_b0050","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1007\/BF01181531","article-title":"The formation and maturation of synapses in the visual cortex of the rat. II. Quantitative analysis","volume":"12","author":"Blue","year":"1983","journal-title":"J Neurocytol"},{"key":"10.1016\/j.bbi.2025.106077_b0055","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1210\/en.2013-1874","article-title":"Prenatal stress and stress coping style interact to predict metabolic risk in male rats","volume":"155","author":"Boersma","year":"2014","journal-title":"Endocrinology"},{"key":"10.1016\/j.bbi.2025.106077_b0060","doi-asserted-by":"crossref","first-page":"109","DOI":"10.14336\/AD.2014.0305","article-title":"Metabolic syndrome, aging and involvement of oxidative stress","volume":"6","author":"Bonomini","year":"2015","journal-title":"Aging Dis."},{"key":"10.1016\/j.bbi.2025.106077_b0065","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.cobeha.2015.11.018","article-title":"The stress Acceleration Hypothesis: Effects of early-life adversity on emotion circuits and behavior","volume":"7","author":"Callaghan","year":"2016","journal-title":"Curr. Opin. Behav. Sci."},{"key":"10.1016\/j.bbi.2025.106077_b0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.midw.2021.102939","article-title":"Stress during pregnancy and the development of diseases in the offspring: a systematic-review and meta-analysis","volume":"97","author":"Caparros-Gonzalez","year":"2021","journal-title":"Midwifery"},{"key":"10.1016\/j.bbi.2025.106077_b0075","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2021.725547","article-title":"Neuronal mitochondrial dysfunction and bioenergetic failure in inflammation-associated depression","author":"Casaril","year":"2021","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.bbi.2025.106077_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.euroneuro.2022.02.002","article-title":"Preclinical animal models of mental illnesses to translate findings from the bench to the bedside: Molecular brain mechanisms and peripheral biomarkers associated to early life stress or immune challenges","author":"Cattane","year":"2022","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.bbi.2025.106077_b0085","doi-asserted-by":"crossref","DOI":"10.1007\/s12035-019-1523-4","article-title":"Transcriptional signatures of cognitive impairment in rat exposed to prenatal stress","author":"Cattaneo","year":"2019","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.bbi.2025.106077_b0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2024.108686","article-title":"Early life adversities, psychopathologies and novel pharmacological strategies","author":"Cattaneo","year":"2024","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.bbi.2025.106077_b0095","doi-asserted-by":"crossref","DOI":"10.1038\/s41398-023-02653-6","article-title":"Vulnerability and resilience to prenatal stress exposure: behavioral and molecular characterization in adolescent rats","volume":"13","author":"Creutzberg","year":"2023","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.bbi.2025.106077_b0100","article-title":"Sex-specific metabolic and inflammatory alterations in adult animals vulnerable to prenatal stress exposure","volume":"138","author":"D\u2019Aprile","year":"2025","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2025.106077_b0105","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1016\/j.psyneuen.2011.12.016","article-title":"Prenatal psychobiological predictors of anxiety risk in preadolescent children","volume":"37","author":"Davis","year":"2012","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.bbi.2025.106077_b0110","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.neuroscience.2015.03.046","article-title":"Brain glucose metabolism in an animal model of depression","volume":"295","author":"Detka","year":"2015","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbi.2025.106077_b0115","doi-asserted-by":"crossref","DOI":"10.1159\/000531588","article-title":"Depression in women: potential biological and sociocultural factors driving the sex effect","author":"Di Benedetto","year":"2024","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.bbi.2025.106077_b0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.yfrne.2024.101121","article-title":"Neuroendocrine mechanisms in the links between early life stress, affect, and youth substance use: a conceptual model for the study of sex and gender differences","author":"Donovan","year":"2024","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.bbi.2025.106077_b0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.ynstr.2020.100251","article-title":"Proteomic and mitochondrial adaptations to early-life stress are distinct in juveniles and adults","volume":"13","author":"Eagleson","year":"2020","journal-title":"Neurobiol. Stress"},{"key":"10.1016\/j.bbi.2025.106077_b0130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fphar.2022.1075746","article-title":"Prenatal stress induces a depressive-like phenotype in adolescent rats: the key role of TGF-\u03b21 pathway","volume":"13","author":"Fidilio","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.bbi.2025.106077_b0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.tins.2008.02.008","article-title":"The mitochondrial impairment, oxidative stress and neurodegeneration connection: reality or just an attractive hypothesis?","author":"Fukui","year":"2008","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.bbi.2025.106077_b0140","doi-asserted-by":"crossref","first-page":"7351","DOI":"10.1007\/s12035-016-9807-4","article-title":"The effect of chronic tianeptine administration on the brain mitochondria: direct links with an animal model of depression","volume":"53","author":"G\u0142ombik","year":"2016","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.bbi.2025.106077_b0145","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.psyneuen.2015.06.015","article-title":"Maternal stress predicts altered biogenesis and the profile of mitochondrial proteins in the frontal cortex and hippocampus of adult offspring rats","volume":"60","author":"G\u0142ombik","year":"2015","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.bbi.2025.106077_b0150","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/j.physbeh.2012.02.011","article-title":"Sex differences in the programming effects of prenatal stress on psychopathology and stress responses: an evolutionary perspective","volume":"106","author":"Glover","year":"2012","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.bbi.2025.106077_b0155","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1038\/s41386-018-0195-5","article-title":"Early life stress leads to sex differences in development of depressive-like outcomes in a mouse model","volume":"44","author":"Goodwill","year":"2019","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbi.2025.106077_b0160","doi-asserted-by":"crossref","first-page":"8940","DOI":"10.1523\/JNEUROSCI.0026-12.2012","article-title":"Oxidative phosphorylation, not glycolysis, powers presynaptic and postsynaptic mechanisms underlying brain information processing","volume":"32","author":"Hall","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2025.106077_b0165","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41537-023-00357-w","article-title":"Nicotinamide ameliorates mitochondria-related neuronal apoptosis and cognitive impairment via the NAD+\/SIRT3 pathway","volume":"9","author":"Hao","year":"2023","journal-title":"Schizophrenia"},{"key":"10.1016\/j.bbi.2025.106077_b0170","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.neuron.2012.08.019","article-title":"Synaptic energy use and supply","volume":"75","author":"Harris","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.bbi.2025.106077_b0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.yfrne.2019.100796","article-title":"Neurobiological mechanisms underlying sex-related differences in stress-related disorders: Effects of neuroactive steroids on the hippocampus","author":"Hillerer","year":"2019","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.bbi.2025.106077_b0180","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2018.00306","article-title":"The mitochondrion as potential interface in early-life stress brain programming","author":"Hoffmann","year":"2018","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.bbi.2025.106077_b0185","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2021.726457","article-title":"Micronutrients may be a unique weapon against the neurotoxic triad of excitotoxicity, oxidative stress and neuroinflammation: a perspective","volume":"15","author":"Holton","year":"2021","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.bbi.2025.106077_b0190","first-page":"363","article-title":"Control mechanisms in mitochondrial oxidative phosphorylation","volume":"8","author":"Hroudov\u00e1","year":"2013","journal-title":"Neural Regen. Res."},{"key":"10.1016\/j.bbi.2025.106077_b0195","first-page":"1","article-title":"The development of synapses in striate cortex of man","volume":"6","author":"Huttenlocher","year":"1987","journal-title":"Hum. Neurobiol."},{"key":"10.1016\/j.bbi.2025.106077_b0200","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.ijdevneu.2009.09.003","article-title":"Repeated restraint stress and corticosterone injections during late pregnancy alter GAP-43 expression in the hippocampus and prefrontal cortex of rat pups","volume":"28","author":"Jutapakdeegul","year":"2010","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.bbi.2025.106077_b0205","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0126929","article-title":"Association between prenatal and postnatal psychological distress and toddler cognitive development: a systematic review","volume":"10","author":"Kingston","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.bbi.2025.106077_b0210","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1007\/s10995-013-1418-3","article-title":"Prenatal and postnatal maternal mental health and school-age child development: a systematic review","volume":"18","author":"Kingston","year":"2014","journal-title":"Matern. Child Health J."},{"key":"10.1016\/j.bbi.2025.106077_b0215","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1007\/s10578-012-0291-4","article-title":"Prenatal and postpartum maternal psychological distress and infant development: a systematic review","volume":"43","author":"Kingston","year":"2012","journal-title":"Child Psychiatry Hum. Dev."},{"key":"10.1016\/j.bbi.2025.106077_bib401","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1038\/bjc.2012.288","article-title":"Antenatal maternal bereavement and childhood cancer in the offspring: a population-based cohort study in 6 million children","volume":"107","author":"Li","year":"2012","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.bbi.2025.106077_b0220","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fnmol.2020.00158","article-title":"Prenatal stress impairs postnatal learning and memory development via disturbance of the cGMP\u2013PKG pathway and oxidative phosphorylation in the hippocampus of rats","volume":"13","author":"Li","year":"2020","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.bbi.2025.106077_b0225","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.1074911","article-title":"PPAR\u03b1: an emerging target of metabolic syndrome, neurodegenerative and cardiovascular diseases","author":"Lin","year":"2022","journal-title":"Front. Endocrinol. (lausanne)"},{"key":"10.1016\/j.bbi.2025.106077_b0230","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.ijdevneu.2010.08.002","article-title":"Developmental pathology, dopamine, stress and schizophrenia","volume":"29","author":"Lodge","year":"2011","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.bbi.2025.106077_b0235","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1111\/bph.13659","article-title":"Distribution, physiology and pharmacology of relaxin-3\/RXFP3 systems in brain","volume":"174","author":"Ma","year":"2016","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bbi.2025.106077_b0240","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.psyneuen.2015.07.005","article-title":"Activation of presynaptic oxytocin receptors enhances glutamate release in the ventral hippocampus of prenatally restraint stressed rats","volume":"62","author":"Mairesse","year":"2015","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.bbi.2025.106077_b0245","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fcell.2021.653384","article-title":"Exposure to prenatal stress is associated with an excitatory\/inhibitory imbalance in rat prefrontal cortex and amygdala and an increased risk for emotional dysregulation","volume":"9","author":"Marchisella","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.bbi.2025.106077_b0250","doi-asserted-by":"crossref","first-page":"17143","DOI":"10.1523\/JNEUROSCI.1040-12.2012","article-title":"Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus","volume":"32","author":"Marrocco","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2025.106077_b0255","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.mce.2013.04.014","article-title":"Steroid hormone synthesis in mitochondria","volume":"379","author":"Miller","year":"2013","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.bbi.2025.106077_b0260","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41398-023-02701-1","article-title":"Bdnf-Nrf-2 crosstalk and emotional behavior are disrupted in a sex-dependent fashion in adolescent mice exposed to maternal stress or maternal obesity","volume":"13","author":"Musillo","year":"2023","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.bbi.2025.106077_b0265","doi-asserted-by":"crossref","DOI":"10.3390\/antiox10111734","article-title":"Peroxisome proliferator-activated receptors (Ppars) and oxidative stress in physiological conditions and in cancer","author":"Muzio","year":"2021","journal-title":"Antioxidants"},{"key":"10.1016\/j.bbi.2025.106077_b0270","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/antiox9090774","article-title":"Human relaxin-2 (Serelaxin) attenuates oxidative stress in cardiac muscle cells exposed in vitro to hypoxia\u2013reoxygenation. evidence for the involvement of reduced glutathione up-regulation","volume":"9","author":"Nistri","year":"2020","journal-title":"Antioxidants"},{"key":"10.1016\/j.bbi.2025.106077_b0275","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1016\/j.biopsych.2022.11.023","article-title":"Prenatal stress and the developing brain: postnatal environments promoting resilience","volume":"93","author":"Nolvi","year":"2023","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2025.106077_b0280","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2024.111162","article-title":"Emotional dysregulation following prenatal stress is associated with altered prefrontal cortex responsiveness to an acute challenge in adolescence","volume":"136","author":"Orso","year":"2025","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2025.106077_b0285","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fnbeh.2017.00113","article-title":"Long-term sex-dependent vulnerability to metabolic challenges in prenatally stressed rats","volume":"11","author":"Panetta","year":"2017","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.bbi.2025.106077_b0290","doi-asserted-by":"crossref","DOI":"10.3390\/ijms222111798","article-title":"Cell cycle regulation of hippocampal progenitor cells in experimental models of depression and after treatment with fluoxetine","volume":"22","author":"Patr\u00edcio","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbi.2025.106077_b0295","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/nmeth.4197","article-title":"Salmon provides fast and bias-aware quantification of transcript expression","volume":"14","author":"Patro","year":"2017","journal-title":"Nat. Methods"},{"key":"10.1016\/j.bbi.2025.106077_b0300","article-title":"Psychological stress and Mitochondria: a Conceptual Framework","author":"Picard","year":"2018","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.bbi.2025.106077_b0305","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1080\/10253890.2021.1978425","article-title":"Prenatal stress promotes insulin resistance without inflammation or obesity in C57BL\/6J male mice","volume":"24","author":"Quiroga","year":"2021","journal-title":"Stress"},{"key":"10.1016\/j.bbi.2025.106077_b0310","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1111\/bph.13564","article-title":"Relaxin\u2019 the brain: a case for targeting the nucleus incertus network and relaxin-3\/RXFP3 system in neuropsychiatric disorders","volume":"174","author":"Rajesh Kumar","year":"2017","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bbi.2025.106077_b0315","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1038\/nbt.2931","article-title":"Normalization of RNA-seq data using factor analysis of control genes or samples","volume":"32","author":"Risso","year":"2014","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.bbi.2025.106077_b0320","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbr.2018.06.027","article-title":"Maternal stress during pregnancy induces depressive-like behavior only in female offspring and correlates to their hippocampal Avp and Oxt receptor expression","volume":"353","author":"Schmidt","year":"2018","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.bbi.2025.106077_b0330","doi-asserted-by":"crossref","unstructured":"Sharma, R., Yang, Y., Sharma, A., Awasthi, S., Awasthi, Y.C., 2004. Antioxidant Role of Glutathione S-Transferases: Protection Against Oxidant Toxicity and Regulation of Stress-Mediated Apoptosis. Antioxid Redox Signal 6.","DOI":"10.1089\/152308604322899350"},{"key":"10.1016\/j.bbi.2025.106077_b0335","article-title":"Mitochondria, energetics, epigenetics, and cellular responses to stress","author":"Shaughnessy","year":"2015","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.bbi.2025.106077_b0340","doi-asserted-by":"crossref","DOI":"10.1002\/dmrr.3502","article-title":"Metabolic syndrome and cardiovascular diseases: going beyond traditional risk factors","author":"Silveira Rossi","year":"2022","journal-title":"Diabetes Metab. Res. Rev."},{"key":"10.1016\/j.bbi.2025.106077_b0345","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.12688\/f1000research.7563.1","article-title":"Differential analyses for RNA-seq: transcript-level estimates improve gene-level inferences","volume":"4","author":"Soneson","year":"2015","journal-title":"F1000Res"},{"key":"10.1016\/j.bbi.2025.106077_b0350","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1007\/s11064-008-9838-y","article-title":"Prenatal stress causes oxidative damage to mitochondrial DNA in hippocampus of offspring rats","volume":"34","author":"Song","year":"2009","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.bbi.2025.106077_b0355","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/dev.22305","article-title":"Sex differences in the vulnerability of the hippocampus to prenatal stress","volume":"64","author":"Soti","year":"2022","journal-title":"Dev. Psychobiol."},{"key":"10.1016\/j.bbi.2025.106077_b0360","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2016.11.088","article-title":"The role of mitochondria in metabolism and cell death","author":"Vakifahmetoglu-Norberg","year":"2017","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbi.2025.106077_b0365","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1016\/j.euroneuro.2012.09.011","article-title":"Vulnerability versus resilience to prenatal stress in male and female rats; Implications from gene expression profiles in the hippocampus and frontal cortex","volume":"23","author":"Van den Hove","year":"2013","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.bbi.2025.106077_b0370","doi-asserted-by":"crossref","first-page":"331","DOI":"10.21307\/ane-2020-029","article-title":"Decreased serotonin content and release in the ventral hippocampus of prenatally stressed male rats in response to forced swim test","volume":"80","author":"V\u00e1squez","year":"2020","journal-title":"Acta Neurobiol. Exp. (Wars)"},{"key":"10.1016\/j.bbi.2025.106077_b0375","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.ynstr.2016.08.004","article-title":"Prenatal stressors in rodents: Effects on behavior","volume":"6","author":"Weinstock","year":"2017","journal-title":"Neurobiol. Stress"},{"key":"10.1016\/j.bbi.2025.106077_b0380","doi-asserted-by":"crossref","first-page":"849","DOI":"10.2174\/1568026615666150827095102","article-title":"Relationships between Mitochondria and Neuroinflammation: Implications for Alzheimer\u2019s Disease","volume":"16","author":"Wilkins","year":"2016","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/j.bbi.2025.106077_b0390","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1177\/01926233211046933","article-title":"Comparative milestones in rodent and human postnatal central nervous system development","volume":"49","author":"Zeiss","year":"2021","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.bbi.2025.106077_b0395","doi-asserted-by":"crossref","DOI":"10.1016\/j.ynstr.2021.100333","article-title":"Prenatal stress leads to deficits in brain development, mood related behaviors and gut microbiota in offspring","volume":"15","author":"Zhang","year":"2021","journal-title":"Neurobiol. Stress"},{"key":"10.1016\/j.bbi.2025.106077_b0400","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1002\/jnr.20338","article-title":"Prenatal stress causes gender-dependent neuronal loss and oxidative stress in rat hippocampus","volume":"78","author":"Zhu","year":"2004","journal-title":"J. Neurosci. Res."}],"container-title":["Brain, Behavior, and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159125003125?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159125003125?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T22:00:26Z","timestamp":1761256826000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889159125003125"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":79,"alternative-id":["S0889159125003125"],"URL":"https:\/\/doi.org\/10.1016\/j.bbi.2025.106077","relation":{},"ISSN":["0889-1591"],"issn-type":[{"value":"0889-1591","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transcriptional imprints of prenatal stress: sex- and time-specific signatures in early neurodevelopment","name":"articletitle","label":"Article Title"},{"value":"Brain, Behavior, and Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbi.2025.106077","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"106077"}}