{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T17:42:54Z","timestamp":1793727774610,"version":"4.6.1"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,17]],"date-time":"2026-12-17T00:00:00Z","timestamp":1797465600000},"content-version":"am","delay-in-days":319,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000005","name":"US Department of Defense","doi-asserted-by":"publisher","award":["W81XWH 2210646"],"award-info":[{"award-number":["W81XWH 2210646"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000005","name":"US Department of Defense","doi-asserted-by":"publisher","award":["W81XWH2110885"],"award-info":[{"award-number":["W81XWH2110885"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000005","name":"US Department of Defense","doi-asserted-by":"publisher","award":["W81XWH2110756"],"award-info":[{"award-number":["W81XWH2110756"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain, Behavior, and Immunity"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.bbi.2025.106219","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T00:28:11Z","timestamp":1765412891000},"page":"106219","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["NPD1\/GPR37 signaling protects against painful traumatic brain injury and comorbidities by regulating demyelination, glial responses, and neuroinflammation in the mouse brain"],"prefix":"10.1016","volume":"132","author":[{"given":"Junli","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Runda","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharat","family":"Chandra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haichen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9355-3688","authenticated-orcid":false,"given":"Ru-Rong","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbi.2025.106219_b0010","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2312662120","article-title":"The neurobiology of stress: Vulnerability, resilience, and major depression","volume":"120","author":"Akil","year":"2023","journal-title":"PNAS"},{"issue":"Pt 3","key":"10.1016\/j.bbi.2025.106219_b0015","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.expneurol.2015.02.011","article-title":"White matter involvement after TBI: Clues to axon and myelin repair capacity","volume":"275","author":"Armstrong","year":"2016","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bbi.2025.106219_b0020","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.tins.2024.07.003","article-title":"White matter damage and degeneration in traumatic brain injury","volume":"47","author":"Armstrong","year":"2024","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.bbi.2025.106219_b0025","doi-asserted-by":"crossref","DOI":"10.3390\/cells9020506","article-title":"G-Protein-coupled receptors in CNS: a potential therapeutic target for intervention in neurodegenerative disorders and associated cognitive deficits","volume":"9","author":"Azam","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.bbi.2025.106219_b0030","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.5664\/jcsm.7482","article-title":"Increased sleep disturbances and pain in veterans with comorbid traumatic brain injury and posttraumatic stress disorder","volume":"14","author":"Balba","year":"2018","journal-title":"J. Clin. Sleep Med."},{"key":"10.1016\/j.bbi.2025.106219_b0035","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1038\/s41467-021-21940-8","article-title":"Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice","volume":"12","author":"Bang","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbi.2025.106219_b0040","doi-asserted-by":"crossref","first-page":"3568","DOI":"10.1172\/JCI99888","article-title":"GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain","volume":"128","author":"Bang","year":"2018","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbi.2025.106219_b0045","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1385\/MN:32:1:089","article-title":"Lipid signaling in neural plasticity, brain repair, and neuroprotection","volume":"32","author":"Bazan","year":"2005","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.bbi.2025.106219_b0050","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1750-3639.2005.tb00513.x","article-title":"Neuroprotectin D1 (NPD1): a DHA-derived mediator that protects brain and retina against cell injury-induced oxidative stress","volume":"15","author":"Bazan","year":"2005","journal-title":"Brain Pathol."},{"key":"10.1016\/j.bbi.2025.106219_b0055","doi-asserted-by":"crossref","first-page":"3318","DOI":"10.1021\/acschemneuro.3c00479","article-title":"Orphan G Protein-coupled Receptor GPR37 as an Emerging Therapeutic Target","volume":"14","author":"Bolinger","year":"2023","journal-title":"ACS Chem. Nerosci."},{"key":"10.1016\/j.bbi.2025.106219_b0060","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.pain.2013.04.037","article-title":"Polymorphisms in the glucocorticoid receptor co-chaperone FKBP5 predict persistent musculoskeletal pain after traumatic stress exposure","volume":"154","author":"Bortsov","year":"2013","journal-title":"Pain"},{"key":"10.1016\/j.bbi.2025.106219_b0065","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1089\/neu.2014.3352","article-title":"Long-Term Consequences of Traumatic Brain Injury: Current Status of potential Mechanisms of Injury and Neurological Outcomes","volume":"32","author":"Bramlett","year":"2015","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.bbi.2025.106219_b0070","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1038\/s41583-018-0057-5","article-title":"Microglial signatures and their role in health and disease","volume":"19","author":"Butovsky","year":"2018","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.bbi.2025.106219_b0075","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1523\/JNEUROSCI.4178-07.2008","article-title":"A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function","volume":"28","author":"Cahoy","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2025.106219_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuint.2023.105630","article-title":"Mechanisms and treatments of chronic pain after traumatic brain injury","volume":"171","author":"Chen","year":"2023","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.bbi.2025.106219_b0085","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1007\/s12264-023-01030-z","article-title":"Double-Edged Mossy Cells in Temporal Lobe Epilepsy: Evil in the Early stage through a BDNF-Dependent Strengthening Dentate Gyrus Circuit","volume":"39","author":"Cheng","year":"2023","journal-title":"Neurosci. Bull."},{"key":"10.1016\/j.bbi.2025.106219_b0090","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1038\/nature04223","article-title":"BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain","volume":"438","author":"Coull","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.bbi.2025.106219_b0095","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1089\/neu.2015.4087","article-title":"Trigeminal Pain Molecules, Allodynia, and Photosensitivity are Pharmacologically and Genetically Modulated in a Model of Traumatic Brain Injury","volume":"33","author":"Daiutolo","year":"2016","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.bbi.2025.106219_b0100","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1146\/annurev-neuro-110719-095912","article-title":"Endogenous Opioids at the Intersection of Opioid Addiction, Pain, and Depression: the Search for a Precision Medicine Approach","volume":"43","author":"Emery","year":"2020","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.bbi.2025.106219_b0105","doi-asserted-by":"crossref","first-page":"4891","DOI":"10.1523\/JNEUROSCI.21-13-04891.2001","article-title":"Brain-derived neurotrophic factor increases in the uninjured dorsal root ganglion neurons in selective spinal nerve ligation model","volume":"21","author":"Fukuoka","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2025.106219_b0110","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.2522\/ptj.20130597","article-title":"Chronic stress, cortisol dysfunction, and pain: a psychoneuroendocrine rationale for stress management in pain rehabilitation","volume":"94","author":"Hannibal","year":"2014","journal-title":"Phys. Ther."},{"key":"10.1016\/j.bbi.2025.106219_b0115","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.biopsych.2021.09.024","article-title":"Mental Health Consequences of Traumatic Brain Injury","volume":"91","author":"Howlett","year":"2022","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2025.106219_b0120","doi-asserted-by":"crossref","first-page":"2737","DOI":"10.1007\/s10072-020-04458-7","article-title":"Post-Traumatic stress Disorder after Traumatic Brain Injury-a Systematic Review and Meta-Analysis","volume":"41","author":"Iljazi","year":"2020","journal-title":"Neurol. Sci."},{"key":"10.1016\/j.bbi.2025.106219_b0125","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/S0092-8674(01)00407-X","article-title":"An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin","volume":"105","author":"Imai","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.bbi.2025.106219_b0130","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1093\/pm\/pnx153","article-title":"Chronic Pain after Traumatic Brain Injury: Pathophysiology and Pain Mechanisms","volume":"19","author":"Irvine","year":"2018","journal-title":"Pain Med."},{"key":"10.1016\/j.bbi.2025.106219_b0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2019.112976","article-title":"Enhanced descending pain facilitation in acute traumatic brain injury","volume":"320","author":"Irvine","year":"2019","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bbi.2025.106219_b0140","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1146\/annurev-pharmtox-051921-084047","article-title":"Specialized Pro-Resolving Mediators as Resolution Pharmacology for the Control of Pain and Itch","volume":"63","author":"Ji","year":"2023","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.bbi.2025.106219_b0145","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1111\/bph.13125","article-title":"The contribution of astrocytes and microglia to traumatic brain injury","volume":"173","author":"Karve","year":"2016","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bbi.2025.106219_b0150","first-page":"5","article-title":"RNA-seq analysis is easy as 1-2-3 with limma","volume":"F1000Res","author":"Law","year":"2016","journal-title":"Glimma and edgeR."},{"key":"10.1016\/j.bbi.2025.106219_b0155","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1007\/s12264-022-00845-6","article-title":"Astrocytes in Post-traumatic stress Disorder","volume":"38","author":"Li","year":"2022","journal-title":"Neurosci. Bull."},{"key":"10.1016\/j.bbi.2025.106219_b0160","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/nature21029","article-title":"Neurotoxic reactive astrocytes are induced by activated microglia","volume":"541","author":"Liddelow","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.bbi.2025.106219_b0165","doi-asserted-by":"crossref","first-page":"8407","DOI":"10.1523\/JNEUROSCI.3458-17.2018","article-title":"A Functional riboSNitch in the 3' Untranslated Region of FKBP5 Alters MicroRNA-320a Binding Efficiency and Mediates Vulnerability to Chronic Post-Traumatic Pain","volume":"38","author":"Linnstaedt","year":"2018","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2025.106219_b0170","doi-asserted-by":"crossref","first-page":"2414","DOI":"10.1002\/glia.23480","article-title":"Glio- and neuro-protection by prosaposin is mediated by orphan G-protein coupled receptors GPR37L1 and GPR37","volume":"66","author":"Liu","year":"2018","journal-title":"Glia"},{"key":"10.1016\/j.bbi.2025.106219_b0175","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1097\/j.pain.0000000000003084","article-title":"Neuroinflammation drives sex-dependent effects on pain and negative affect in a murine model of repeated mild traumatic brain injury","volume":"165","author":"Liu","year":"2024","journal-title":"Pain"},{"key":"10.1016\/j.bbi.2025.106219_b0180","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1101\/lm.54603","article-title":"BDNF and activity-dependent synaptic modulation","volume":"10","author":"Lu","year":"2003","journal-title":"Learn. Mem."},{"key":"10.1016\/j.bbi.2025.106219_b0185","doi-asserted-by":"crossref","first-page":"2774","DOI":"10.1172\/JCI25420","article-title":"A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease","volume":"115","author":"Lukiw","year":"2005","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbi.2025.106219_b0190","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/S1474-4422(22)00309-X","article-title":"Traumatic brain injury: progress and challenges in prevention, clinical care, and research","volume":"21","author":"Maas","year":"2022","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.bbi.2025.106219_b0195","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2022.854396","article-title":"Mild traumatic brain injury results in significant and lasting cortical demyelination","volume":"13","author":"Mahoney","year":"2022","journal-title":"Front. Neurol."},{"key":"10.1016\/j.bbi.2025.106219_b0200","doi-asserted-by":"crossref","first-page":"9846","DOI":"10.1073\/pnas.0703368104","article-title":"GPR37 associates with the dopamine transporter to modulate dopamine uptake and behavioral responses to dopaminergic drugs","volume":"104","author":"Marazziti","year":"2007","journal-title":"PNAS"},{"key":"10.1016\/j.bbi.2025.106219_b0205","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1038\/nn1971","article-title":"New insights into BDNF function in depression and anxiety","volume":"10","author":"Martinowich","year":"2007","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbi.2025.106219_b0210","doi-asserted-by":"crossref","first-page":"10680","DOI":"10.1096\/fj.201900070R","article-title":"Protective effects of GPR37 via regulation of inflammation and multiple cell death pathways after ischemic stroke in mice","volume":"33","author":"McCrary","year":"2019","journal-title":"FASEB J."},{"key":"10.1016\/j.bbi.2025.106219_b0215","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1523\/JNEUROSCI.0733-19.2019","article-title":"Revisiting the stress concept: implications for affective disorders","volume":"40","author":"McEwen","year":"2020","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbi.2025.106219_b0220","doi-asserted-by":"crossref","DOI":"10.1002\/glia.24513","article-title":"Transient demyelination causes long-term cognitive impairment, myelin alteration and network synchrony defects","author":"Mercier","year":"2024","journal-title":"Glia"},{"key":"10.1016\/j.bbi.2025.106219_b0225","doi-asserted-by":"crossref","first-page":"9529","DOI":"10.1073\/pnas.1219004110","article-title":"GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin","volume":"110","author":"Meyer","year":"2013","journal-title":"PNAS"},{"key":"10.1016\/j.bbi.2025.106219_b0230","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.neuropharm.2011.04.028","article-title":"Pain and post traumatic stress disorder - review of clinical and experimental evidence","volume":"62","author":"Moeller-Bertram","year":"2012","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.bbi.2025.106219_b0235","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s40035-021-00232-7","article-title":"Ecto-GPR37: a potential biomarker for Parkinson's disease","volume":"10","author":"Morato","year":"2021","journal-title":"Transl Neurodegener"},{"key":"10.1016\/j.bbi.2025.106219_b0240","doi-asserted-by":"crossref","first-page":"436","DOI":"10.25122\/jml-2022-0120","article-title":"Evaluation of post-traumatic stress disorder (PTSD) and related comorbidities in clinical studies","volume":"15","author":"Muresanu","year":"2022","journal-title":"J. Med. Life"},{"key":"10.1016\/j.bbi.2025.106219_b0245","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1038\/nrd3366","article-title":"Potential therapeutic uses of BDNF in neurological and psychiatric disorders","volume":"10","author":"Nagahara","year":"2011","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.bbi.2025.106219_b0250","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1001\/jama.300.6.711","article-title":"Prevalence of chronic pain after traumatic brain injury: a systematic review","volume":"300","author":"Nampiaparampil","year":"2008","journal-title":"J. Am. Med. Assoc."},{"key":"10.1016\/j.bbi.2025.106219_b0255","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0014-2999(03)01272-X","article-title":"The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review","volume":"463","author":"Prut","year":"2003","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bbi.2025.106219_b0260","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abi5811","article-title":"Osteocalcin attenuates oligodendrocyte differentiation and myelination via GPR37 signaling in the mouse brain","volume":"7","author":"Qian","year":"2021","journal-title":"Sci. Adv."},{"key":"10.1016\/j.bbi.2025.106219_b0265","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S0091-3057(00)00374-9","article-title":"Long-lasting delayed hyperalgesia after subchronic swim stress","volume":"67","author":"Quintero","year":"2000","journal-title":"Pharmacol. Biochem. Behav"},{"key":"10.1016\/j.bbi.2025.106219_b0270","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/nature13479","article-title":"Pro-resolving lipid mediators are leads for resolution physiology","volume":"510","author":"Serhan","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.bbi.2025.106219_b0275","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1176\/appi.ajp.20240536","article-title":"Neurobiology and Treatment of Posttraumatic stress Disorder","volume":"181","author":"Shalev","year":"2024","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.bbi.2025.106219_b0280","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/nrneurol.2017.13","article-title":"The far-reaching scope of neuroinflammation after traumatic brain injury","volume":"13","author":"Simon","year":"2017","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.bbi.2025.106219_b0285","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.neubiorev.2019.10.007","article-title":"The interaction between stress and chronic pain through the lens of threat learning","volume":"107","author":"Timmers","year":"2019","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.bbi.2025.106219_b0290","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1038\/nprot.2007.44","article-title":"The use of the elevated plus maze as an assay of anxiety-related behavior in rodents","volume":"2","author":"Walf","year":"2007","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.bbi.2025.106219_b0295","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.expneurol.2007.03.031","article-title":"Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury","volume":"206","author":"Wang","year":"2007","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bbi.2025.106219_b0300","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.bbi.2023.05.008","article-title":"Cannabidiol alleviates neuroinflammation and attenuates neuropathic pain via targeting FKBP5","volume":"111","author":"Wang","year":"2023","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbi.2025.106219_b0305","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1089\/neu.2019.6890","article-title":"Damage mechanisms to oligodendrocytes and white matter in central nervous system injury: the Australian Context","volume":"37","author":"Warnock","year":"2020","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.bbi.2025.106219_b0310","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1007\/s12264-023-01075-0","article-title":"Peripheral BDNF Regulates Somatosensory-Sympathetic Coupling in Brachial Plexus Avulsion-Induced Neuropathic Pain","volume":"39","author":"Xian","year":"2023","journal-title":"Neurosci. Bull."},{"key":"10.1016\/j.bbi.2025.106219_b0315","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.cjtee.2018.02.003","article-title":"Current understanding of neuroinflammation after traumatic brain injury and cell-based therapeutic opportunities","volume":"21","author":"Xiong","year":"2018","journal-title":"Chin. J. Traumatol."},{"key":"10.1016\/j.bbi.2025.106219_b0320","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2025.107746","article-title":"Neuroprotectin D1 and GPR37 protect against chemotherapy-induced peripheral neuropathy and the transition from acute to chronic pain","volume":"216","author":"Xu","year":"2025","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.bbi.2025.106219_b0325","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1002\/ana.23928","article-title":"Neuroprotectin\/protectin D1 protects against neuropathic pain in mice after nerve trauma","volume":"74","author":"Xu","year":"2013","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.bbi.2025.106219_b0330","doi-asserted-by":"crossref","first-page":"10884","DOI":"10.1038\/ncomms10884","article-title":"G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination","volume":"7","author":"Yang","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbi.2025.106219_b0335","article-title":"Inflammation and Infection in Pain and the Role of GPR37","volume":"23","author":"Zhang","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"2709\u20132726","key":"10.1016\/j.bbi.2025.106219_b0340","doi-asserted-by":"crossref","first-page":"e2709","DOI":"10.1016\/j.neuron.2023.05.022","article-title":"PD-L1\/PD-1 checkpoint pathway regulates hippocampal neuronal excitability and learning and memory behavior","volume":"111","author":"Zhao","year":"2023","journal-title":"Neuron"},{"key":"10.1016\/j.bbi.2025.106219_b0345","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1097\/ALN.0000000000005553","article-title":"General Anesthesia-activated Neurons in the Central Amygdala Mediate Antinociception: Distinct Roles in Acute versus Chronic Phases of Nerve Injury","volume":"143","author":"Zhao","year":"2025","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bbi.2025.106219_b0350","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2023.108476","article-title":"Immunotherapies in chronic pain through modulation of neuroimmune interactions","volume":"248","author":"Zhao","year":"2023","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.bbi.2025.106219_b0355","series-title":"Neuroimmune Interactions in Pain : Mechanisms and Therapeutics","first-page":"223","article-title":"Immunotherapy and Pain","author":"Zhao","year":"2023"},{"key":"10.1016\/j.bbi.2025.106219_b0360","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.bbi.2017.02.002","article-title":"Therapeutic potential of an anti-high mobility group box-1 monoclonal antibody in epilepsy","volume":"64","author":"Zhao","year":"2017","journal-title":"Brain Behav. Immun."}],"container-title":["Brain, Behavior, and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159125004611?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159125004611?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T13:39:26Z","timestamp":1782481166000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889159125004611"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":71,"alternative-id":["S0889159125004611"],"URL":"https:\/\/doi.org\/10.1016\/j.bbi.2025.106219","relation":{},"ISSN":["0889-1591"],"issn-type":[{"value":"0889-1591","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"NPD1\/GPR37 signaling protects against painful traumatic brain injury and comorbidities by regulating demyelination, glial responses, and neuroinflammation in the mouse brain","name":"articletitle","label":"Article Title"},{"value":"Brain, Behavior, and Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbi.2025.106219","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"106219"}}