{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:08:46Z","timestamp":1789085326238,"version":"build-2803163510"},"reference-count":78,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T00:00:00Z","timestamp":1767571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["F31MH119745"],"award-info":[{"award-number":["F31MH119745"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["F32MH119750"],"award-info":[{"award-number":["F32MH119750"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH107033"],"award-info":[{"award-number":["R01MH107033"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["T32NS096050"],"award-info":[{"award-number":["T32NS096050"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007197","name":"U.S. Public Health Service","doi-asserted-by":"publisher","award":["UL1TR000454"],"award-info":[{"award-number":["UL1TR000454"]}],"id":[{"id":"10.13039\/100007197","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004764","name":"American Honda Motor","doi-asserted-by":"publisher","award":["F32MH119750"],"award-info":[{"award-number":["F32MH119750"]}],"id":[{"id":"10.13039\/100004764","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004764","name":"American Honda Motor","doi-asserted-by":"publisher","award":["R01MH107033"],"award-info":[{"award-number":["R01MH107033"]}],"id":[{"id":"10.13039\/100004764","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004764","name":"American Honda Motor","doi-asserted-by":"publisher","award":["F31MH119745"],"award-info":[{"award-number":["F31MH119745"]}],"id":[{"id":"10.13039\/100004764","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000874","name":"Brain and Behavior Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000874","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001068","name":"Dana Foundation","doi-asserted-by":"publisher","award":["CADF49143"],"award-info":[{"award-number":["CADF49143"]}],"id":[{"id":"10.13039\/100001068","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Institutes of Health National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain, Behavior, and Immunity"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.bbi.2025.106252","type":"journal-article","created":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T16:56:50Z","timestamp":1767113810000},"page":"106252","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Effects of Dopaminergic Therapy with Levodopa (L-DOPA) on Fear and Anxiety-Related Circuits and Symptoms in Patients with Depression and Higher Inflammation"],"prefix":"10.1016","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-9155-1907","authenticated-orcid":false,"given":"Genevieve E.","family":"Craig","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neeti D.","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mandakh","family":"Bekhbat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate P.","family":"Revill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Lucido","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changdo","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evanthia C.","family":"Wommack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy M.","family":"Baer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebrahim","family":"Haroon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew H.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer C.","family":"Felger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbi.2025.106252_b0260","series-title":"Manual of the State-Trait anxiety Inventory","author":"Spielberger","year":"1979"},{"issue":"8","key":"10.1016\/j.bbi.2025.106252_b0225","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1001\/archpsyc.1988.01800320058007","article-title":"A structured interview guide for the Hamilton Depression Rating Scale","volume":"45","author":"Williams","year":"1988","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.bbi.2025.106252_b0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbi.2019.05.011","article-title":"Inflammation and decreased functional connectivity in a widely-distributed network in depression: Centralized effects in the ventral medial prefrontal cortex","volume":"80","author":"Yin","year":"2019","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbi.2025.106252_b0005","doi-asserted-by":"crossref","unstructured":"Michopoulos V, Powers A, Gillespie C, Ressler K, Jovanovic T. Inflammation in Fear- and Anxiety-Based Disorders: PTSD, GAD, and Beyond. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2017;42(1):254\u201370. Epub 2016 Aug 1doi: 10.1038\/npp.2016.146. PubMed PMID: 27510423; PMCID: PMC5143487.","DOI":"10.1038\/npp.2016.146"},{"key":"10.1016\/j.bbi.2025.106252_b0015","doi-asserted-by":"crossref","unstructured":"van Eeden WA, El Filali E, van Hemert AM, Carlier IVE, Penninx B, Lamers F, Schoevers R, Giltay EJ. Basal and LPS-stimulated inflammatory markers and the course of anxiety symptoms. Brain, behavior, and immunity. 2021;98:378-87. Epub 2021 Sep 9. doi: 10.1016\/j.bbi.2021.09.001. PubMed PMID: 34509625.","DOI":"10.1016\/j.bbi.2021.09.001"},{"key":"10.1016\/j.bbi.2025.106252_b0020","doi-asserted-by":"crossref","unstructured":"Lindqvist D, Mellon SH, Dhabhar FS, Yehuda R, Grenon SM, Flory JD, Bierer LM, Abu-Amara D, Coy M, Makotkine I, Reus VI, Aschbacher K, Bersani FS, Marmar CR, Wolkowitz OM. Increased circulating blood cell counts in combat-related PTSD: Associations with inflammation and PTSD severity. Psychiatry research. 2017;258:330-6. Epub 2017 Aug 2doi: 10.1016\/j.psychres.2017.08.052. PubMed PMID: 28942957.","DOI":"10.1016\/j.psychres.2017.08.052"},{"key":"10.1016\/j.bbi.2025.106252_b0030","doi-asserted-by":"crossref","unstructured":"Furman D, Campisi J, Verdin E, Carrera-Bastos P, Targ S, Franceschi C, Ferrucci L, Gilroy DW, Fasano A, Miller GW, Miller AH, Mantovani A, Weyand CM, Barzilai N, Goronzy JJ, Rando TA, Effros RB, Lucia A, Kleinstreuer N, Slavich GM. Chronic inflammation in the etiology of disease across the life span. Nat Med. 2019;25(12):1822-32. Epub 2019 Dec 5. doi: 10.1038\/s41591-019-0675-0. PubMed PMID: 31806905; PMCID: PMC7147972.","DOI":"10.1038\/s41591-019-0675-0"},{"key":"10.1016\/j.bbi.2025.106252_b0035","doi-asserted-by":"crossref","unstructured":"Haroon E, Daguanno A, Woolwine B, Goldsmith D, Baer W, Wommack E, Felger J, Miller A. Antidepressant treatment resistance is associated with increased inflammatory markers in patients with major depressive disorder. Psychoneuroendocrinology. 2018;95:43\u20139. Epub 2018 May 19. doi: 10.1016\/j.psyneuen.2018.05.026. PubMed PMID: 29800779; PMCID: PMC6427066.","DOI":"10.1016\/j.psyneuen.2018.05.026"},{"key":"10.1016\/j.bbi.2025.106252_b0040","doi-asserted-by":"crossref","unstructured":"Amitai M, Taler M, Carmel M, Michaelovsky E, Eilat T, Yablonski M, Orpaz N, Chen A, Apter A, Weizman A, Fennig S. The Relationship Between Plasma Cytokine Levels and Response to Selective Serotonin Reuptake Inhibitor Treatment in Children and Adolescents with Depression and\/or Anxiety Disorders. J Child Adolesc Psychopharmacol. 2016;26(8):727-32. Epub 2016 Jan 15. doi: 10.1089\/cap.2015.0147. PubMed PMID: 26771135.","DOI":"10.1089\/cap.2015.0147"},{"key":"10.1016\/j.bbi.2025.106252_b0050","doi-asserted-by":"crossref","unstructured":"Goldsmith D, Bekhbat M, Mehta N, Felger J. Inflammation-Related Functional and Structural Dysconnectivity as a Pathway to Psychopathology. Biological psychiatry. 2023;93(5):405\u201318. Epub 2022 Nov 9. doi: 10.1016\/j.biopsych.2022.11.003. PubMed PMID: 36725140; PMCID: PMC9895884.","DOI":"10.1016\/j.biopsych.2022.11.003"},{"key":"10.1016\/j.bbi.2025.106252_b0055","doi-asserted-by":"crossref","unstructured":"Menard C, Pfau ML, Hodes GE, Kana V, Wang VX, Bouchard S, Takahashi A, Flanigan ME, Aleyasin H, LeClair KB, Janssen WG, Labont\u00e9 B, Parise EM, Lorsch ZS, Golden SA, Heshmati M, Tamminga C, Turecki G, Campbell M, Fayad ZA, Tang CY, Merad M, Russo SJ. Social stress induces neurovascular pathology promoting depression. Nature neuroscience. 2017;20(12):1752-60. Epub 2017 Nov 13. doi: 10.1038\/s41593-017-0010-3. PubMed PMID: 29184215; PMCID: PMC5726568.","DOI":"10.1038\/s41593-017-0010-3"},{"key":"10.1016\/j.bbi.2025.106252_b0065","doi-asserted-by":"crossref","unstructured":"Felger J, Lotrich F. Inflammatory cytokines in depression: neurobiological mechanisms and therapeutic implications. Neuroscience. 2013;246:199\u2013229. Epub 2013 May 3. doi: 10.1016\/j.neuroscience.2013.04.060. PubMed PMID: 23644052; PMCID: PMC3741070.","DOI":"10.1016\/j.neuroscience.2013.04.060"},{"key":"10.1016\/j.bbi.2025.106252_b0070","doi-asserted-by":"crossref","unstructured":"Harrison NA, Brydon L, Walker C, Gray MA, Steptoe A, Critchley HD. Inflammation causes mood changes through alterations in subgenual cingulate activity and mesolimbic connectivity. Biological psychiatry. 2009;66(5):407-Epub 2009 May 7. doi: 10.1016\/j.biopsych.2009.03.015. PubMed PMID: 19423079; PMCID: PMC2885494.","DOI":"10.1016\/j.biopsych.2009.03.015"},{"key":"10.1016\/j.bbi.2025.106252_b0080","doi-asserted-by":"crossref","unstructured":"Inagaki TK, Muscatell KA, Irwin MR, Cole SW, Eisenberger NI. Inflammation selectively enhances amygdala activity to socially threatening images. Neuroimage. 2012;59(4):3222-6. Epub 2011 Nov 4. doi: 10.1016\/j.neuroimage.2011.10.090. PubMed PMID: 22079507; PMCID: PMC3348143.","DOI":"10.1016\/j.neuroimage.2011.10.090"},{"key":"10.1016\/j.bbi.2025.106252_b0085","doi-asserted-by":"crossref","unstructured":"Davies KA, Cooper E, Voon V, Tibble J, Cercignani M, Harrison NA. Interferon and anti-TNF therapies differentially modulate amygdala reactivity which predicts associated bidirectional changes in depressive symptoms. Molecular psychiatry. 2021;26(9):5150-60. Epub 2020 May 26. doi: 10.1038\/s41380-020-0790-9. PubMed PMID: 32457424; PMCID: PMC8589643.","DOI":"10.1038\/s41380-020-0790-9"},{"key":"10.1016\/j.bbi.2025.106252_b0090","doi-asserted-by":"crossref","unstructured":"O'Donovan A, Chao LL, Paulson J, Samuelson KW, Shigenaga JK, Grunfeld C, Weiner MW, Neylan TC. Altered inflammatory activity associated with reduced hippocampal volume and more severe posttraumatic stress symptoms in Gulf War veterans. Psychoneuroendocrinology. 2015;51:557-66. Epub 2014 Nov doi: 10.1016\/j.psyneuen.2014.11.010. PubMed PMID: 25465168; PMCID: PMC4374733.","DOI":"10.1016\/j.psyneuen.2014.11.010"},{"key":"10.1016\/j.bbi.2025.106252_b0095","doi-asserted-by":"crossref","unstructured":"Cha J, Raj D, Choi KS, Rajendra JK, Nemeroff CB, Felger JC, Craighead WE, Mayberg HS, Dunlop BW. Impact of inflammation on white matter integrity and functional connectivity in chronic major depressive disorder. Biological psychiatry. 2025;S0006-3223(25):01300-9. Epub 2025 Jul 7. doi: 10.1016\/j.biopsych.2025.06.026. PubMed PMID: 40633889; PMCID: PMC12631980.","DOI":"10.1016\/j.biopsych.2025.06.026"},{"key":"10.1016\/j.bbi.2025.106252_b0100","doi-asserted-by":"crossref","unstructured":"Goldsmith DR, Ning CS, Strauss GP, Gross RE, Cooper JA, Wommack EC, Haroon E, Felger JC, Walker EF, Treadway MT, Miller AH. Inflammation is associated with avolition and reduced resting state functional connectivity in corticostriatal reward circuitry in patients with schizophrenia. Neuropsychopharmacology. 2025;50(11):1706-14. Epub 2025 Apr 24. doi: 10.1038\/s41386-025-02114-2. PubMed PMID: 40274974; PMCID: PMC12436628.","DOI":"10.1038\/s41386-025-02114-2"},{"key":"10.1016\/j.bbi.2025.106252_b0105","doi-asserted-by":"crossref","unstructured":"Bekhbat M, Li Z, Mehta ND, Treadway MT, Lucido MJ, Woolwine BJ, Haroon E, Miller AH, Felger JC. Functional connectivity in reward circuitry and symptoms of anhedonia as therapeutic targets in depression with high inflammation: evidence from a dopamine challenge study. Molecular psychiatry. 2022;27(10):4113-Epub 2022 Aug 4. doi: 10.1038\/s41380-022-01715-3. PubMed PMID: 35927580; PMCID: PMC9718669.","DOI":"10.1038\/s41380-022-01715-3"},{"key":"10.1016\/j.bbi.2025.106252_b0110","doi-asserted-by":"crossref","unstructured":"Bekhbat M, Li Z, Dunlop BW, Treadway MT, Mehta ND, Revill KP, Lucido MJ, Hong C, Ashchi A, Wommack EC, Goldsmith DR, Haroon E, Miller AH, Felger JC. Sustained effects of repeated levodopa (L-DOPA) administration on reward circuitry, effort-based motivation, and anhedonia in depressed patients with higher inflammation. Brain, behavior, and immunity. 2025;125:240\u20138. Epub 2024 Dec 16. doi: 10.1016\/j.bbi.2024.12.026. PubMed PMID: 39694342; PMCID: PMC11903141.","DOI":"10.1016\/j.bbi.2024.12.026"},{"key":"10.1016\/j.bbi.2025.106252_b0115","doi-asserted-by":"crossref","unstructured":"Treadway MT, Etuk SM, Cooper JA, Hossein S, Hahn E, Betters SA, Liu S, Arulpragasam AR, DeVries BAM, Irfan N, Nuutinen MR, Wommack EC, Woolwine BJ, Bekhbat M, Kragel PA, Felger JC, Haroon E, Miller AH. A randomized proof-of-mechanism trial of TNF antagonism for motivational deficits and related corticostriatal circuitry in depressed patients with high inflammation. Molecular psychiatry. 2025;30(4):1407-17. Epub 2024 Sept 17. doi: 10.1038\/s41380-024-02751-x. PubMed PMID: 39289477; PMCID: PMC11911248.","DOI":"10.1038\/s41380-024-02751-x"},{"key":"10.1016\/j.bbi.2025.106252_b0120","doi-asserted-by":"crossref","unstructured":"Felger J, Li Z, Haroon E, Woolwine B, Jung M, Hu X, Miller A. Inflammation is associated with decreased functional connectivity within corticostriatal reward circuitry in depression. Molecular psychiatry. 2016;21(10):1358\u201365. Epub 2015 Nov 10. doi: 10.1038\/mp.2015.168. PubMed PMID: 26552591; PMCID: PMC4862934.","DOI":"10.1038\/mp.2015.168"},{"key":"10.1016\/j.bbi.2025.106252_b0125","doi-asserted-by":"crossref","unstructured":"Mehta N, Haroon E, Xu X, Woolwine B, Li Z, Felger J. Inflammation negatively correlates with amygdala-ventromedial prefrontal functional connectivity in association with anxiety in patients with depression: Preliminary results. Brain, behavior, and immunity. 2018;73:725\u201330. Epub 2018 Aug 1. doi: 10.1016\/j.bbi.2018.07.026. PubMed PMID: 30076980; PMCID: PMC6129411.","DOI":"10.1016\/j.bbi.2018.07.026"},{"key":"10.1016\/j.bbi.2025.106252_b0135","doi-asserted-by":"crossref","unstructured":"Mehta ND, Stevens JS, Li Z, Gillespie CF, Fani N, Michopoulos V, Felger JC. Inflammation, reward circuitry and symptoms of anhedonia and PTSD in trauma-exposed women. Social cognitive and affective neuroscience. 2020;15(10):1046-55. Epub 2020 Apr 4. doi: 10.1093\/scan\/nsz100. PubMed PMID: 32291455; PMCID: PMC7657453.","DOI":"10.1093\/scan\/nsz100"},{"key":"10.1016\/j.bbi.2025.106252_b0140","doi-asserted-by":"crossref","unstructured":"Mehta ND, Stevens JS, Li Z, Fani N, Gillespie CF, Ravi M, Michopoulos V, Felger JC. Inflammation, amygdala-ventromedial prefrontal functional connectivity and symptoms of anxiety and PTSD in African American women recruited from an inner-city hospital: Preliminary results. Brain, behavior, and immunity. 2022;105:122-30. Epub 2022 Jun 27. doi: 10.1016\/j.bbi.2022.06.013. PubMed PMID: 35772683; PMCID: PMC11041384.","DOI":"10.1016\/j.bbi.2022.06.013"},{"key":"10.1016\/j.bbi.2025.106252_b0150","doi-asserted-by":"crossref","unstructured":"Felger J, Treadway M. Inflammation Effects on Motivation and Motor Activity: Role of Dopamine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2017;42(1):216\u201341. Epub 2016 Aug 2. doi: 10.1038\/npp.2016.143. PubMed PMID: 27480574; PMCID: PMC5143486.","DOI":"10.1038\/npp.2016.143"},{"key":"10.1016\/j.bbi.2025.106252_b0155","doi-asserted-by":"crossref","unstructured":"Felger JC, Mun J, Kimmel HL, Nye JA, Drake DF, Hernandez CR, Freeman AA, Rye DB, Goodman MM, Howell LL. Chronic interferon-\u03b1 decreases dopamine 2 receptor binding and striatal dopamine release in association with anhedonia-like behavior in nonhuman primates. Neuropsychopharmacology. 2013;38(11):2179-87. Epub 2013 May 9. doi: 10.1038\/npp.2013.115. PubMed PMID: 23657438; PMCID: PMC3773667.","DOI":"10.1038\/npp.2013.115"},{"key":"10.1016\/j.bbi.2025.106252_b0160","doi-asserted-by":"crossref","unstructured":"Yohn SE, Arif Y, Haley A, Tripodi G, Baqi Y, Muller CE, Miguel NS, Correa M, Salamone JD. Effort-related motivational effects of the pro-inflammatory cytokine interleukin-6: pharmacological and neurochemical characterization. Psychopharmacology (Berl). 2016;233(19-20):3575-86. Epub 2016 Aug 6. doi: 10.1007\/s00213-016-4392-9. PubMed PMID: 27497935.","DOI":"10.1007\/s00213-016-4392-9"},{"key":"10.1016\/j.bbi.2025.106252_b0165","doi-asserted-by":"crossref","unstructured":"Bekhbat M, Block AM, Dickinson SY, Tharp GK, Bosinger SE, Felger JC. Neurotransmitter and metabolic effects of interferon-alpha in association with decreased striatal dopamine in a non-human primate model of cytokine-Induced depression. Brain, behavior, and immunity. 2025;125:308-18. Epub 2025 Jan 16. doi: 10.1016\/j.bbi.2025.01.010. PubMed PMID: 39826580; PMCID: PMC11903159.","DOI":"10.1016\/j.bbi.2025.01.010"},{"key":"10.1016\/j.bbi.2025.106252_b0175","doi-asserted-by":"crossref","unstructured":"Berry A, White R, Furman D, Naskolnakorn J, Shah V, D'Esposito M, Jagust W. Dopaminergic Mechanisms Underlying Normal Variation in Trait Anxiety. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2019;39(14):2735\u201344. Epub 2019 Feb 8. doi: 10.1523\/JNEUROSCI.2382-18.2019. PubMed PMID: 30737306; PMCID: PMC6445999.","DOI":"10.1523\/JNEUROSCI.2382-18.2019"},{"key":"10.1016\/j.bbi.2025.106252_b0185","doi-asserted-by":"crossref","unstructured":"Azzinnari D, Sigrist H, Staehli S, Palme R, Hildebrandt T, Leparc G, Hengerer B, Seifritz E, Pryce C. Mouse social stress induces increased fear conditioning, helplessness and fatigue to physical challenge together with markers of altered immune and dopamine function. Neuropharmacology. 2014;85:328\u201341. Epub 2014 Jun 5. doi: 10.1016\/j.neuropharm.2014.05.039. PubMed PMID: 24907589.","DOI":"10.1016\/j.neuropharm.2014.05.039"},{"key":"10.1016\/j.bbi.2025.106252_b0190","doi-asserted-by":"crossref","unstructured":"Felger J, Li L, Marvar P, Woolwine B, Harrison D, Raison C, Miller A. Tyrosine metabolism during interferon-alpha administration: association with fatigue and CSF dopamine concentrations. Brain, behavior, and immunity. 2013;31:153\u201360. Epub 2012 Oct 13. doi: 10.1016\/j.bbi.2012.10.010. PubMed PMID: 23072726; PMCID: PMC3578984.","DOI":"10.1016\/j.bbi.2012.10.010"},{"key":"10.1016\/j.bbi.2025.106252_b0205","doi-asserted-by":"crossref","unstructured":"Esser R, Korn C, Ganzer F, Haaker J. L-DOPA modulates activity in the vmPFC, nucleus accumbens, and VTA during threat extinction learning in humans. eLife. 2021;10:e65280. doi: 10.7554\/eLife.65280. PubMed PMID: 34473055; PMCID: PMC8443250.","DOI":"10.7554\/eLife.65280"},{"key":"10.1016\/j.bbi.2025.106252_b0210","doi-asserted-by":"crossref","unstructured":"Haaker J, Lonsdorf T, Kalisch R. Effects of post-extinction l-DOPA administration on the spontaneous recovery and reinstatement of fear in a human fMRI study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 2015;25(10):1544\u201355. Epub 2015 Jul 21. doi: 10.1016\/j.euroneuro.2015.07.016. PubMed PMID: 26238968.","DOI":"10.1016\/j.euroneuro.2015.07.016"},{"key":"10.1016\/j.bbi.2025.106252_b0220","doi-asserted-by":"crossref","unstructured":"McAllister T, Zafonte R, Jain S, Flashman L, George M, Grant G, He F, Lohr J, Andaluz N, Summerall L, Paulus M, Raman R, Stein M. Randomized Placebo-Controlled Trial of Methylphenidate or Galantamine for Persistent Emotional and Cognitive Symptoms Associated with PTSD and\/or Traumatic Brain Injury. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2016;41(5):1191\u20138. Epub 2015 Sep 11. doi: 10.1038\/npp.2015.282. PubMed PMID: 26361060; PMCID: PMC4793116.","DOI":"10.1038\/npp.2015.282"},{"key":"10.1016\/j.bbi.2025.106252_b0235","doi-asserted-by":"crossref","unstructured":"Singh A, Bekhbat M, Goldsmith DR, Le NA, Wommack EC, Li Z, Haroon E, Felger JC. Lipids and C-reactive protein predict anhedonia and reward circuit functional connectivity responses to anti-cytokine and dopaminergic therapies in patients with depression. Comprehensive psychoneuroendocrinology. 2025;21:100284. Epub 2025 Feb 26. doi: 10.1016\/j.cpnec.2025.100284. PubMed PMID: 39981264; PMCID: PMC11840189.","DOI":"10.1016\/j.cpnec.2025.100284"},{"key":"10.1016\/j.bbi.2025.106252_b0240","doi-asserted-by":"crossref","unstructured":"Ridker PM, Everett BM, Thuren T, MacFadyen JG, Chang WH, Ballantyne C, Fonseca F, Nicolau J, Koenig W, Anker SD, Kastelein JJP, Cornel JH, Pais P, Pella D, Genest J, Cifkova R, Lorenzatti A, Forster T, Kobalava Z, Vida-Simiti L, Flather M, Shimokawa H, Ogawa H, Dellborg M, Rossi PRF, Troquay RPT, Libby P, Glynn RJ, Group CT. Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease. N Engl J Med. 2017;377(12):1119-31. Epub 2017 Aug 29. doi: 10.1056\/NEJMoa1707914. PubMed PMID: 28845751.","DOI":"10.1056\/NEJMoa1707914"},{"key":"10.1016\/j.bbi.2025.106252_b0245","doi-asserted-by":"crossref","unstructured":"Felger JC, Haroon E, Patel TA, Goldsmith DR, Wommack EC, Woolwine BJ, Le NA, Feinberg R, Tansey MG, Miller AH. What does plasma CRP tell us about peripheral and central inflammation in depression? Molecular psychiatry. 2020;25(6):1301-11. Epub 2018 Jun 12. doi: 10.1038\/s41380-018-0096-3. PubMed PMID: 29895893; PMCID: PMC6291384.","DOI":"10.1038\/s41380-018-0096-3"},{"key":"10.1016\/j.bbi.2025.106252_b0250","doi-asserted-by":"crossref","unstructured":"Hamilton M. A rating scale for depression. Journal of neurology, neurosurgery, and psychiatry. 1960;23:56-62. PubMed PMID: 14399272; PMCID: PMC495331.","DOI":"10.1136\/jnnp.23.1.56"},{"key":"10.1016\/j.bbi.2025.106252_b0255","doi-asserted-by":"crossref","unstructured":"Trivedi MH, Rush AJ, Ibrahim HM, Carmody TJ, Biggs MM, Suppes T, Crismon ML, Shores-Wilson K, Toprac MG, Dennehy EB, Witte B, Kashner TM. The Inventory of Depressive Symptomatology, Clinician Rating (IDS-C) and Self-Report (IDS-SR), and the Quick Inventory of Depressive Symptomatology, Clinician Rating (QIDS-C) and Self-Report (QIDS-SR) in public sector patients with mood disorders: a psychometric evaluation. Psychological medicine. 2004;34(1):73-82. Epub 2004 Jan 14. doi: 10.1017\/S0033291703001107. PubMed PMID: 14971628.","DOI":"10.1017\/S0033291703001107"},{"key":"10.1016\/j.bbi.2025.106252_b0275","article-title":"Specific symptom change associated with ecological momentary assessments of intrusive trauma memories","volume":"2(1):18","author":"Pollmann","year":"2024","journal-title":"NPP\u2014Digital Psychiatry and Neuroscience."},{"issue":"3","key":"10.1016\/j.bbi.2025.106252_b0230","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1161\/01.CIR.0000053730.47739.3C","article-title":"Clinical application of C-reactive protein for cardiovascular disease detection and prevention","volume":"107","author":"Ridker","year":"2003","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.bbi.2025.106252_b0200","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/s41398-023-02708-8","article-title":"Fear extinction rescuing effects of dopamine and L-DOPA in the ventromedial prefrontal cortex","volume":"14","author":"Sartori","year":"2024","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.bbi.2025.106252_b0270","doi-asserted-by":"crossref","unstructured":"Blevins CA, Weathers FW, Davis MT, Witte TK, Domino JL. The Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5): Development and Initial Psychometric Evaluation. Journal of traumatic stress. 2015;28(6):489\u201398. Epub 2015 Nov 25. doi: 10.1002\/jts.22059. PubMed PMID: 26606250.","DOI":"10.1002\/jts.22059"},{"key":"10.1016\/j.bbi.2025.106252_b0280","doi-asserted-by":"crossref","unstructured":"Forkus SR, Raudales AM, Rafiuddin HS, Weiss NH, Messman BA, Contractor AA. The Posttraumatic Stress Disorder (PTSD) Checklist for DSM-5: A Systematic Review of Existing Psychometric Evidence. Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association. 2023;30(1):110-21. Epub 2022 Sept 8. doi: 10.1037\/cps0000111. PubMed PMID: 37378352; PMCID: PMC10292741.","DOI":"10.1037\/cps0000111"},{"issue":"7","key":"10.1016\/j.bbi.2025.106252_b0145","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1016\/j.bbi.2011.04.005","article-title":"Acute amygdaloid response to systemic inflammation","volume":"25","author":"Engler","year":"2011","journal-title":"Brain Behav. Immun."},{"issue":"5","key":"10.1016\/j.bbi.2025.106252_b0045","doi-asserted-by":"crossref","first-page":"533","DOI":"10.2174\/1570159X15666171123201142","article-title":"Imaging the Role of Inflammation in Mood and Anxiety-related Disorders","volume":"16","author":"Felger","year":"2018","journal-title":"Curr. Neuropharmacol."},{"issue":"4","key":"10.1016\/j.bbi.2025.106252_b0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/ijnp\/pyu084","article-title":"Levodopa reverses cytokine-induced reductions in striatal dopamine release","volume":"18","author":"Felger","year":"2015","journal-title":"Int. J. Neuropsychopharmacol."},{"issue":"1\u20132","key":"10.1016\/j.bbi.2025.106252_b0195","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/S0006-8993(03)02776-8","article-title":"Mechanism of systemically injected interferon-alpha impeding monoamine biosynthesis in rats: role of nitric oxide as a signal crossing the blood-brain barrier","volume":"978","author":"Kitagami","year":"2003","journal-title":"Brain Res."},{"issue":"1","key":"10.1016\/j.bbi.2025.106252_b0025","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1038\/s41398-025-03372-w","article-title":"Role of inflammation in depressive and anxiety disorders, affect, and cognition: genetic and non-genetic findings in the lifelines cohort study","volume":"15","author":"Mac Giollabhui","year":"2025","journal-title":"Transl. Psychiatry"},{"issue":"1","key":"10.1016\/j.bbi.2025.106252_b0010","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1038\/nri.2015.5","article-title":"The role of inflammation in depression: from evolutionary imperative to modern treatment target","volume":"16","author":"Miller","year":"2016","journal-title":"Nat. Rev. Immunol."},{"issue":"1","key":"10.1016\/j.bbi.2025.106252_b0180","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1038\/s41467-022-29155-1","article-title":"Midbrain projection to the basolateral amygdala encodes anxiety-like but not depression-like behaviors","volume":"13","author":"Morel","year":"2022","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.bbi.2025.106252_b0285","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1002\/mrm.1910150117","article-title":"Three-dimensional magnetization-prepared rapid gradient-echo imaging (3D MP RAGE)","volume":"15","author":"Mugler","year":"1990","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.bbi.2025.106252_b0290","doi-asserted-by":"crossref","unstructured":"Jo HJ, Saad ZS, Simmons WK, Milbury LA, Cox RW. Mapping sources of correlation in resting state FMRI, with artifact detection and removal. Neuroimage. 2010;52(2):571-82. Epub 2010 Apr 24. doi: 10.1016\/j.neuroimage.2010.04.246. PubMed PMID: 20420926; PMCID: PMC2897154.","DOI":"10.1016\/j.neuroimage.2010.04.246"},{"key":"10.1016\/j.bbi.2025.106252_b0295","doi-asserted-by":"crossref","unstructured":"Birn RM, Molloy EK, Patriat R, Parker T, Meier TB, Kirk GR, Nair VA, Meyerand ME, Prabhakaran V. The effect of scan length on the reliability of resting-state fMRI connectivity estimates. Neuroimage. 2013;83:550-8. Epub 2013 Jun 6. doi: 10.1016\/j.neuroimage.2013.05.099. PubMed PMID: 23747458; PMCID: PMC4104183.","DOI":"10.1016\/j.neuroimage.2013.05.099"},{"key":"10.1016\/j.bbi.2025.106252_b0300","doi-asserted-by":"crossref","unstructured":"Goldsmith DR, Bekhbat M, Le NA, Chen X, Woolwine BJ, Li Z, Haroon E, Felger JC. Protein and gene markers of metabolic dysfunction and inflammation together associate with functional connectivity in reward and motor circuits in depression. Brain, behavior, and immunity. 2020;88:193-202. Epub 2020 May 5. doi: 10.1016\/j.bbi.2020.05.013. PubMed PMID: 32387344; PMCID: PMC7415617.","DOI":"10.1016\/j.bbi.2020.05.013"},{"key":"10.1016\/j.bbi.2025.106252_b0305","doi-asserted-by":"crossref","unstructured":"Cullen KR, Westlund MK, Klimes-Dougan B, Mueller BA, Houri A, Eberly LE, Lim KO. Abnormal amygdala resting-state functional connectivity in adolescent depression. JAMA Psychiatry. 2014;71(10):1138-47. Epub 2014 Aug 19. doi: 10.1001\/jamapsychiatry.2014.1087. PubMed PMID: 25133665; PMCID: PMC4378862.","DOI":"10.1001\/jamapsychiatry.2014.1087"},{"issue":"1","key":"10.1016\/j.bbi.2025.106252_b0215","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1038\/s41398-020-00975-3","article-title":"L-DOPA and consolidation of fear extinction learning among women with posttraumatic stress disorder","volume":"10","author":"Cisler","year":"2020","journal-title":"Transl. Psychiatry"},{"issue":"1\u20133","key":"10.1016\/j.bbi.2025.106252_b0060","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S1566-0702(00)00220-4","article-title":"Neural and humoral pathways of communication from the immune system to the brain: parallel or convergent?","volume":"85","author":"Dantzer","year":"2000","journal-title":"Auton. Neurosci."},{"issue":"7","key":"10.1016\/j.bbi.2025.106252_b0310","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1016\/j.neuropsychologia.2012.02.007","article-title":"The role of the human ventral striatum and the medial orbitofrontal cortex in the representation of reward magnitude - an activation likelihood estimation meta-analysis of neuroimaging studies of passive reward expectancy and outcome processing","volume":"50","author":"Diekhof","year":"2012","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.bbi.2025.106252_b0315","doi-asserted-by":"crossref","unstructured":"Stevens J, Jovanovic T, Fani N, Ely T, Glover E, Bradley B, Ressler K. Disrupted amygdala-prefrontal functional connectivity in civilian women with posttraumatic stress disorder. Journal of psychiatric research. 2013;47(10):1469\u201378. Epub 2013 Jul 1. doi: 10.1016\/j.jpsychires.2013.05.031. PubMed PMID: 23827769; PMCID: PMC3743923.","DOI":"10.1016\/j.jpsychires.2013.05.031"},{"key":"10.1016\/j.bbi.2025.106252_b0320","doi-asserted-by":"crossref","unstructured":"McLean C, Asnaani A, Litz B, Hofmann S. Gender differences in anxiety disorders: prevalence, course of illness, comorbidity and burden of illness. Journal of psychiatric research. 2011;45(8):1027\u201335. Epub 2011 Mar 25. doi: 10.1016\/j.jpsychires.2011.03.006. PubMed PMID: 21439576; PMCID: PMC3135672.","DOI":"10.1016\/j.jpsychires.2011.03.006"},{"key":"10.1016\/j.bbi.2025.106252_b0325","doi-asserted-by":"crossref","unstructured":"Swartz JR, Carranza AF, Tully LM, Knodt AR, Jiang J, Irwin MR, Hostinar CE. Associations between peripheral inflammation and resting state functional connectivity in adolescents. Brain, behavior, and immunity. 2021;95:96-105. Epub 2021 Feb 23. doi: 10.1016\/j.bbi.2021.02.018. PubMed PMID: 33631285; PMCID: PMC8241234.","DOI":"10.1016\/j.bbi.2021.02.018"},{"key":"10.1016\/j.bbi.2025.106252_b0330","doi-asserted-by":"crossref","unstructured":"Leschak CJ, Dutcher JM, Haltom KEB, Breen EC, Bower JE, Eisenberger NI. Associations between amygdala reactivity to social threat, perceived stress and C-reactive protein in breast cancer survivors. Social cognitive and affective neuroscience. 2020;15(10):1056-63. Epub 2020 Feb 11. doi: 10.1093\/scan\/nsz103. PubMed PMID: 32039441; PMCID: PMC7657448.","DOI":"10.1093\/scan\/nsz103"},{"key":"10.1016\/j.bbi.2025.106252_b0335","doi-asserted-by":"crossref","unstructured":"Gong J, Chen G, Chen F, Zhong S, Chen P, Zhong H, Lai S, Tang G, Wang J, Luo Z, Qi Z, Jia Y, Huang L, Wang Y. Association between resting-state functional connectivity of amygdala subregions and peripheral pro-inflammation cytokines levels in bipolar disorder. Brain imaging and behavior. 2022;16(4):1614\u201326. Epub 2022 Feb 17. doi: 10.1007\/s11682-022-00636-7. PubMed PMID: 35175549.","DOI":"10.1007\/s11682-022-00636-7"},{"key":"10.1016\/j.bbi.2025.106252_b0340","doi-asserted-by":"crossref","unstructured":"Miller GE, White SF, Chen E, Nusslock R. Association of Inflammatory Activity With Larger Neural Responses to Threat and Reward Among Children Living in Poverty. Am J Psychiatry. 2021;178(4):313-20. Epub 2020 Nov 19. doi: 10.1176\/appi.ajp.2020.20050635. PubMed PMID: 33207936; PMCID: PMC8016707.","DOI":"10.1176\/appi.ajp.2020.20050635"},{"key":"10.1016\/j.bbi.2025.106252_b0345","doi-asserted-by":"crossref","unstructured":"Boukezzi S, Costi S, Shin LM, Kim-Schulze S, Cathomas F, Collins A, Russo SJ, Morris LS, Murrough JW. Exaggerated amygdala response to threat and association with immune hyperactivity in depression. Brain, behavior, and immunity. 2022;104:205-12. Epub 2022 May 27. doi: 10.1016\/j.bbi.2022.05.015. PubMed PMID: 35636614; PMCID: PMC10966680.","DOI":"10.1016\/j.bbi.2022.05.015"},{"key":"10.1016\/j.bbi.2025.106252_b0350","doi-asserted-by":"crossref","unstructured":"Cichocki AC, Zinbarg RE, Craske MG, Chat IK, Young KS, Bookheimer SY, Nusslock R. Transdiagnostic symptom of depression and anxiety associated with reduced gray matter volume in prefrontal cortex. Psychiatry research Neuroimaging. 2024;339:111791. Epub 2024 Feb 10. doi: 10.1016\/j.pscychresns.2024.111791. PubMed PMID: 38359709; PMCID: PMC10938645.","DOI":"10.1016\/j.pscychresns.2024.111791"},{"key":"10.1016\/j.bbi.2025.106252_b0355","doi-asserted-by":"crossref","unstructured":"Duek O, Spiller TR, Rubenstein A, Pietrzak RH, Harpaz-Rotem I. Exploration of a Novel Model of Intrusive Symptoms in Posttraumatic Stress Disorder Among US Veterans. JAMA network open. 2022;5(3):e223555. Epub 2022 Mar 1. doi: 10.1001\/jamanetworkopen.2022.3555. PubMed PMID: 35311966; PMCID: PMC8938717.","DOI":"10.1001\/jamanetworkopen.2022.3555"},{"key":"10.1016\/j.bbi.2025.106252_b0360","doi-asserted-by":"crossref","unstructured":"Remy P, Doder M, Lees A, Turjanski N, Brooks D. Depression in Parkinson's disease: loss of dopamine and noradrenaline innervation in the limbic system. Brain : a journal of neurology. 2005;128(Pt 6):1314-22. Epub 2005 Feb 16. doi: 10.1093\/brain\/awh445. PubMed PMID: 15716302.","DOI":"10.1093\/brain\/awh445"},{"issue":"6","key":"10.1016\/j.bbi.2025.106252_b0265","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1037\/0022-006X.56.6.893","article-title":"An inventory for measuring clinical anxiety: psychometric properties","volume":"56","author":"Beck","year":"1988","journal-title":"J. Consult. Clin. Psychol."},{"issue":"10","key":"10.1016\/j.bbi.2025.106252_b0075","first-page":"1044","article-title":"Dopaminergic mechanisms of reduced basal ganglia responses to hedonic reward during interferon alfa administration","volume":"69","author":"Capuron","year":"2012","journal-title":"JAMA Psychiat."},{"issue":"1","key":"10.1016\/j.bbi.2025.106252_b0365","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1177\/1756285613495723","article-title":"Anxiety in Parkinson\u2019s disease: identification and management","volume":"7","author":"Chen","year":"2014","journal-title":"Ther. Adv. Neurol. Disord."},{"key":"10.1016\/j.bbi.2025.106252_b0370","doi-asserted-by":"crossref","unstructured":"Hinkle JT, Mills KA, Morrow CB, Pontone GM. Anxiety Change After Dopamine Therapy in Parkinson Disease is Independent of Motor Improvement. The American Journal of Geriatric Psychiatry. 2024;32(2):220-9. Epub 2023 Sep 10. doi: 10.1016\/j.jagp.2023.09.001. PubMed PMID: 37867011; PMCID: PMC10846408.","DOI":"10.1016\/j.jagp.2023.09.001"},{"key":"10.1016\/j.bbi.2025.106252_b0375","doi-asserted-by":"crossref","unstructured":"Bloch Y, Aviram S, Segev A, Nitzan U, Levkovitz Y, Braw Y, Mimouni Bloch A. Methylphenidate Reduces State Anxiety During a Continuous Performance Test That Distinguishes Adult ADHD Patients From Controls. Journal of attention disorders. 2017;21(1):46-51. Epub 2016 Jul 28. doi: 10.1177\/1087054712474949. PubMed PMID: 23413186.","DOI":"10.1177\/1087054712474949"},{"key":"10.1016\/j.bbi.2025.106252_b0380","doi-asserted-by":"crossref","unstructured":"Zhang X, Flick K, Rizzo M, Pignatelli M, Tonegawa S. Dopamine induces fear extinction by activating the reward-responding amygdala neurons. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(18):e2501331122. Epub 2025 Apr 28. doi: 10.1073\/pnas.2501331122. PubMed PMID: 40294263; PMCID: PMC12067255.","DOI":"10.1073\/pnas.2501331122"},{"key":"10.1016\/j.bbi.2025.106252_b0385","doi-asserted-by":"crossref","unstructured":"Mac Giollabhui N, Madison AA, Lydston M, Lenoel Quang E, Miller AH, Liu RT. Effect of Anti-Inflammatory Treatment on Depressive Symptom Severity and Anhedonia in Depressed Individuals With Elevated Inflammation: Systematic Review and Meta-Analysis of Randomized Controlled Trials. Am J Psychiatry. 2025:appiajp20241115. Epub 2025 Dec 10. doi: 10.1176\/appi.ajp.20241115. PubMed PMID: 41366844.","DOI":"10.1176\/appi.ajp.20241115"},{"key":"10.1016\/j.bbi.2025.106252_b0390","doi-asserted-by":"crossref","unstructured":"Cools R, D'Esposito M. Inverted-U-shaped dopamine actions on human working memory and cognitive control. Biological psychiatry. 2011;69(12):e113-25. Epub 2011 May 4. doi: 10.1016\/j.biopsych.2011.03.028. PubMed PMID: 21531388; PMCID: PMC3111448.","DOI":"10.1016\/j.biopsych.2011.03.028"}],"container-title":["Brain, Behavior, and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159125004945?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159125004945?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T23:36:04Z","timestamp":1789083364000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889159125004945"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":78,"alternative-id":["S0889159125004945"],"URL":"https:\/\/doi.org\/10.1016\/j.bbi.2025.106252","relation":{},"ISSN":["0889-1591"],"issn-type":[{"value":"0889-1591","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of Dopaminergic Therapy with Levodopa (L-DOPA) on Fear and Anxiety-Related Circuits and Symptoms in Patients with Depression and Higher Inflammation","name":"articletitle","label":"Article Title"},{"value":"Brain, Behavior, and Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbi.2025.106252","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"106252"}}