{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:52:44Z","timestamp":1791921164708,"version":"4.3.4"},"reference-count":77,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:00:00Z","timestamp":1768435200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100022278","name":"Gueules Cass\u00e9es Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022278","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","award":["197462"],"award-info":[{"award-number":["197462"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","award":["223414"],"award-info":[{"award-number":["223414"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014262","name":"Soci\u00e9t\u00e9 Fran\u00e7aise d\u2019Anesth\u00e9sie et de R\u00e9animation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014262","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain, Behavior, and Immunity"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.bbi.2026.106293","type":"journal-article","created":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T07:38:04Z","timestamp":1768549084000},"page":"106293","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Chemogenetic activation of oxytocinergic neurons modulates acute neuroinflammation and improves brain development after pediatric traumatic brain injury"],"prefix":"10.1016","volume":"133","author":[{"given":"Marit","family":"Knoop","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ece","family":"Trak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Laure","family":"Possovre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohan","family":"van de Looij","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Schirmbeck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Ceyz\u00e9riat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Luc","family":"Pitetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Sanches","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Musardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Millet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stergios","family":"Tsartsalis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin B.","family":"Tournier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilla","family":"Bellone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane V.","family":"Sizonenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Jacquens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Baud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.bbi.2026.106293_b0005","doi-asserted-by":"crossref","first-page":"82","DOI":"10.2176\/nmc.ra.2016-0191","article-title":"Pediatric Traumatic Brain Injury: Characteristic Features, Diagnosis, and Management","volume":"57","author":"Araki","year":"2017","journal-title":"Neurologia Medico-Chirurgica"},{"key":"10.1016\/j.bbi.2026.106293_b0010","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.expneurol.2019.02.016","article-title":"Sex differences in pediatric traumatic brain injury","volume":"317","author":"Arambula","year":"2019","journal-title":"Experimental Neurology"},{"issue":"11","key":"10.1016\/j.bbi.2026.106293_b0015","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3003158","article-title":"Oxytocin neurons drive melanocortin circuit maturation via vesicle release during a neonatal critical period","volume":"23","author":"Barelle","year":"2025","journal-title":"PLOS Biology"},{"issue":"1","key":"10.1016\/j.bbi.2026.106293_b0020","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1609\/icwsm.v3i1.13937","article-title":"Gephi: an Open Source Software for Exploring and Manipulating Networks","volume":"3","author":"Bastian","year":"2009","journal-title":"Proceedings of the International AAAI Conference on Web and Social Media"},{"key":"10.1016\/j.bbi.2026.106293_b0025","first-page":"62964","article-title":"Magnetic Isolation of Microglial Cells from Neonate Mouse for Primary Cell Cultures","volume":"185","author":"Bokobza","year":"2022","journal-title":"Journal of Visualized Experiments"},{"key":"10.1016\/j.bbi.2026.106293_b0030","doi-asserted-by":"crossref","DOI":"10.1080\/0022250X.1972.9989806","article-title":"Factoring and weighting approaches to status scores and clique identification","author":"Bonacich","year":"1972","journal-title":"Journal of Mathematical Sociology."},{"key":"10.1016\/j.bbi.2026.106293_b0035","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.cortex.2022.05.014","article-title":"Resting-state network organisation in children with traumatic brain injury","volume":"154","author":"Botchway","year":"2022","journal-title":"Cortex"},{"issue":"4","key":"10.1016\/j.bbi.2026.106293_b0040","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.tics.2013.02.007","article-title":"The neurochemistry of music","volume":"17","author":"Chanda","year":"2013","journal-title":"Trends in Cognitive Sciences"},{"key":"10.1016\/j.bbi.2026.106293_b0045","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.neuroimage.2014.10.026","article-title":"Accelerated Microstructure Imaging via Convex Optimization (AMICO) from diffusion MRI data","volume":"105","author":"Daducci","year":"2015","journal-title":"NeuroImage"},{"key":"10.1016\/j.bbi.2026.106293_b0050","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.wneu.2016.03.045","article-title":"Epidemiology of Global Pediatric Traumatic Brain Injury: Qualitative Review","volume":"91","author":"Dewan","year":"2016","journal-title":"World Neurosurgery"},{"issue":"2","key":"10.1016\/j.bbi.2026.106293_b0055","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.expneurol.2008.03.012","article-title":"Mild traumatic brain injury to the infant mouse causes robust white matter axonal degeneration which precedes apoptotic death of cortical and thalamic neurons","volume":"211","author":"Dikranian","year":"2008","journal-title":"Experimental Neurology"},{"issue":"1","key":"10.1016\/j.bbi.2026.106293_b0060","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1186\/s12974-018-1302-6","article-title":"\u03b1-Synuclein disrupts the anti-inflammatory role of Drd2 via interfering \u03b2-arrestin2-TAB1 interaction in astrocytes","volume":"15","author":"Du","year":"2018","journal-title":"Journal of Neuroinflammation"},{"issue":"4","key":"10.1016\/j.bbi.2026.106293_b0065","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.yhbeh.2013.08.012","article-title":"Sex differences in oxytocin receptor binding in forebrain regions: Correlations with social interest in brain region- and sex- specific ways","volume":"64","author":"Dumais","year":"2013","journal-title":"Hormones and Behavior"},{"issue":"1","key":"10.1016\/j.bbi.2026.106293_b0070","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3390\/ijms25010007","article-title":"Peripheral Branch Injury Induces Oxytocin Receptor Expression at the Central Axon terminals of Primary Sensory Neurons","volume":"25","author":"El Heni","year":"2024","journal-title":"International Journal of Molecular Sciences"},{"issue":"30","key":"10.1016\/j.bbi.2026.106293_b0075","doi-asserted-by":"crossref","first-page":"12691","DOI":"10.1074\/jbc.M116.769695","article-title":"NLRC3 protein inhibits inflammation by disrupting NALP3 inflammasome assembly via competition with the adaptor protein ASC for pro-caspase-1 binding","volume":"292","author":"Eren","year":"2017","journal-title":"The Journal of Biological Chemistry"},{"issue":"6","key":"10.1016\/j.bbi.2026.106293_b0080","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1093\/brain\/awv075","article-title":"Disconnection of network hubs and cognitive impairment after traumatic brain injury","volume":"138","author":"Fagerholm","year":"2015","journal-title":"Brain"},{"issue":"10","key":"10.1016\/j.bbi.2026.106293_b0085","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1038\/nmeth.3125","article-title":"Neuronal morphometry directly from bitmap images","volume":"11","author":"Ferreira","year":"2014","journal-title":"Nature Methods"},{"issue":"11","key":"10.1016\/j.bbi.2026.106293_b0090","doi-asserted-by":"crossref","first-page":"3071","DOI":"10.1007\/s00381-023-06173-y","article-title":"An update on pediatric traumatic brain injury","volume":"39","author":"Figaji","year":"2023","journal-title":"Child\u2019s Nervous System"},{"issue":"1","key":"10.1016\/j.bbi.2026.106293_b0095","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1038\/s41467-020-14762-7","article-title":"Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery","volume":"11","author":"Forbes","year":"2020","journal-title":"Nature Communications"},{"issue":"4","key":"10.1016\/j.bbi.2026.106293_b0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.107580","article-title":"Netrin-G1 Regulates Microglial Accumulation along Axons and Supports the Survival of Layer V Neurons in the Postnatal Mouse Brain","volume":"31","author":"Fujita","year":"2020","journal-title":"Cell Reports"},{"issue":"6","key":"10.1016\/j.bbi.2026.106293_b0105","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1002\/jnr.23356","article-title":"Glucose pathways adaptation supports acquisition of activated microglia phenotype","volume":"92","author":"Gimeno-Bay\u00f3n","year":"2014","journal-title":"Journal of Neuroscience Research"},{"key":"10.1016\/j.bbi.2026.106293_b0110","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.psyneuen.2019.03.019","article-title":"Chemogenetic activation of oxytocin neurons: Temporal dynamics, hormonal release, and behavioral consequences","volume":"106","author":"Grund","year":"2019","journal-title":"Psychoneuroendocrinology"},{"issue":"1","key":"10.1016\/j.bbi.2026.106293_b0115","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-020-17514-9","article-title":"Knockout of reactive astrocyte activating factors slows disease progression in an ALS mouse model","volume":"11","author":"Guttenplan","year":"2020","journal-title":"Nature Communications"},{"issue":"4","key":"10.1016\/j.bbi.2026.106293_b0120","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1038\/nrneurol.2015.13","article-title":"The role of inflammation in perinatal brain injury","volume":"11","author":"Hagberg","year":"2015","journal-title":"Nature Reviews. Neurology"},{"issue":"7781","key":"10.1016\/j.bbi.2026.106293_b0125","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1038\/s41586-019-1716-z","article-title":"Hierarchical organization of cortical and thalamic connectivity","volume":"575","author":"Harris","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.bbi.2026.106293_b0130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2008.08.076","article-title":"Axl\u2212\/\u2212 mice have delayed recovery and prolonged axonal damage following cuprizone toxicity","volume":"1240","author":"Hoehn","year":"2008","journal-title":"Brain Research"},{"key":"10.1016\/j.bbi.2026.106293_b0135","article-title":"Microglial immune regulation by epigenetic reprogramming through histone H3K27 acetylation in neuroinflammation","volume":"14","author":"Huang","year":"2023","journal-title":"Frontiers in Immunology"},{"issue":"1","key":"10.1016\/j.bbi.2026.106293_b0140","doi-asserted-by":"crossref","first-page":"e6","DOI":"10.5334\/jors.ae","volume":"1","year":"2013","journal-title":"Journal of Open Research Software"},{"key":"10.1016\/j.bbi.2026.106293_b0145","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.bbi.2024.04.029","article-title":"Deleterious effect of sustained neuroinflammation in pediatric traumatic brain injury","volume":"120","author":"Jacquens","year":"2024","journal-title":"Brain, Behavior, and Immunity"},{"issue":"19","key":"10.1016\/j.bbi.2026.106293_b0150","doi-asserted-by":"crossref","DOI":"10.3390\/ijms231911193","article-title":"Neuro-Inflammation Modulation and Post-Traumatic Brain Injury Lesions: from Bench to Bed-Side","volume":"23","author":"Jacquens","year":"2022","journal-title":"International Journal of Molecular Sciences"},{"issue":"10","key":"10.1016\/j.bbi.2026.106293_b0155","first-page":"1297","article-title":"The prostaglandin EP4 receptor is a master regulator of the expression of PGE2 receptors following inflammatory activation in human monocytic cells. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of","volume":"1863","author":"Kashmiry","year":"2018","journal-title":"Lipids"},{"issue":"1","key":"10.1016\/j.bbi.2026.106293_b0160","doi-asserted-by":"crossref","first-page":"5290","DOI":"10.1038\/s41467-021-25595-3","article-title":"Microglia have a grip on brain microvasculature","volume":"12","author":"Kisler","year":"2021","journal-title":"Nature Communications"},{"issue":"23","key":"10.1016\/j.bbi.2026.106293_b0165","doi-asserted-by":"crossref","DOI":"10.3390\/cells11233899","article-title":"The Role of Oxytocin in Abnormal Brain Development: effect on Glial Cells and Neuroinflammation","volume":"11","author":"Knoop","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.bbi.2026.106293_b0170","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.pediatrneurol.2024.07.011","article-title":"Long-Term Neurodevelopmental Outcome of Children with Mild Traumatic Brain Injury","volume":"160","author":"Kooper","year":"2024","journal-title":"Pediatric Neurology"},{"key":"10.1016\/j.bbi.2026.106293_b0175","doi-asserted-by":"crossref","unstructured":"Korotkevich, G., Sukhov, V., Budin, N., Shpak, B., Artyomov, M. N., & Sergushichev, A. (2021). Fast gene set enrichment analysis (p. 060012). bioRxiv. https:\/\/doi.org\/10.1101\/060012.","DOI":"10.1101\/060012"},{"key":"10.1016\/j.bbi.2026.106293_b0180","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.pediatrneurol.2024.04.030","article-title":"Long-Term Quality of Life after Pediatric Traumatic Brain Injury Treated in the Intensive Care Unit","volume":"157","author":"Ky\u00f6sti","year":"2024","journal-title":"Pediatric Neurology"},{"issue":"1","key":"10.1016\/j.bbi.2026.106293_b0185","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.immuni.2019.11.013","article-title":"Immune Sensing of Cell Death through Recognition of Histone Sequences by C-Type Lectin-Receptor-2d Causes Inflammation and Tissue Injury","volume":"52","author":"Lai","year":"2020","journal-title":"Immunity"},{"issue":"1","key":"10.1016\/j.bbi.2026.106293_b0190","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.bioactmat.2020.01.005","article-title":"Angiogenic peptide hydrogels for treatment of traumatic brain injury","volume":"5","author":"Ma","year":"2020","journal-title":"Bioactive Materials"},{"issue":"8","key":"10.1016\/j.bbi.2026.106293_b0195","doi-asserted-by":"crossref","DOI":"10.1038\/nmeth.1641","article-title":"Functional ultrasound imaging of the brain","volume":"8","author":"Mac\u00e9","year":"2011","journal-title":"Nature Methods"},{"key":"10.1016\/j.bbi.2026.106293_b0200","doi-asserted-by":"crossref","unstructured":"Mairesse, J., Zinni, M., Pansiot, J., Hassan-Abdi, R., Demene, C., Colella, M., Charriaut-Marlangue, C., Rideau Batista Novais, A., Tanter, M., Maccari, S., Gressens, P., Vaiman, D., Soussi-Yanicostas, N., & Baud, O. (2019). Oxytocin receptor agonist reduces perinatal brain damage by targeting microglia. Glia, 67(2), 345\u2013359. https:\/\/doi.org\/10.1002\/glia.23546.","DOI":"10.1002\/glia.23546"},{"issue":"6301","key":"10.1016\/j.bbi.2026.106293_b0205","doi-asserted-by":"crossref","DOI":"10.1126\/science.aad8670","article-title":"Microglia development follows a stepwise program to regulate brain homeostasis","volume":"353","author":"Matcovitch-Natan","year":"2016","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.bbi.2026.106293_b0210","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0006-8993(99)02418-X","article-title":"LPS-induced Fos expression in oxytocin and vasopressin neurons of the rat hypothalamus","volume":"858","author":"Matsunaga","year":"2000","journal-title":"Brain Research"},{"issue":"5","key":"10.1016\/j.bbi.2026.106293_b0215","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1093\/brain\/awv066","article-title":"Roles of microglia in brain development, tissue maintenance and repair","volume":"138","author":"Michell-Robinson","year":"2015","journal-title":"Brain"},{"issue":"4","key":"10.1016\/j.bbi.2026.106293_b0220","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1089\/gg.2017.0017","article-title":"Sex-specific differences in Oxytocin Receptor Expression and Function for Parental Behavior","volume":"1","author":"Mitre","year":"2017","journal-title":"Gender and the Genome"},{"key":"10.1016\/j.bbi.2026.106293_b0225","doi-asserted-by":"crossref","DOI":"10.1016\/j.infbeh.2020.101482","article-title":"Neuroendocrine mechanisms involved in the physiological effects caused by skin-to-skin contact \u2013 with a particular focus on the oxytocinergic system","volume":"61","author":"Moberg","year":"2020","journal-title":"Infant Behavior and Development"},{"key":"10.1016\/j.bbi.2026.106293_b0230","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1038\/s42003-022-03879-8","article-title":"Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats","volume":"5","author":"Nishimura","year":"2022","journal-title":"Communications Biology"},{"issue":"3","key":"10.1016\/j.bbi.2026.106293_b0235","doi-asserted-by":"crossref","first-page":"398","DOI":"10.3758\/BF03195394","article-title":"EthoVision: a versatile tracking system for automation of behavioral experiments","volume":"33","author":"Noldus","year":"2001","journal-title":"Behavior Research Methods, Instruments & Computers"},{"issue":"1","key":"10.1016\/j.bbi.2026.106293_b0240","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s40478-023-01515-y","article-title":"A single mild juvenile TBI in male mice leads to regional brain tissue abnormalities at 12months of age that correlate with cognitive impairment at the middle age","volume":"11","author":"Obenaus","year":"2023","journal-title":"Acta Neuropathologica Communications"},{"issue":"12","key":"10.1016\/j.bbi.2026.106293_b0245","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1038\/nm.3407","article-title":"Development, maintenance and disruption of the blood-brain barrier","volume":"19","author":"Obermeier","year":"2013","journal-title":"Nature Medicine"},{"issue":"1","key":"10.1016\/j.bbi.2026.106293_b0250","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41398-021-01361-3","article-title":"Maternal immune activation generates anxiety in offspring: a translational meta-analysis","volume":"11","author":"Quagliato","year":"2021","journal-title":"Translational Psychiatry"},{"key":"10.1016\/j.bbi.2026.106293_b0255","doi-asserted-by":"crossref","unstructured":"Rokicki, J., Kaufmann, T., Glas\u00f8deLange, A.-M., Meer, D. van der, Bahrami, S., Sartorius, A. M., K.Haukvik, U., EielSteen, N., Emanuel, S., Stein, D. J., N\u00e6rland, T., Andreassen, O. A., Westlye, L. T., & Quintana, D. (2021). Oxytocin receptor expression patterns in the human brain across development. OSF Preprints. https:\/\/doi.org\/10.31219\/osf.io\/j3b5d.","DOI":"10.31219\/osf.io\/j3b5d"},{"issue":"3","key":"10.1016\/j.bbi.2026.106293_b0260","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0061-21.2021","article-title":"Intranasal Administration of Oxytocin Attenuates Social Recognition Deficits and Increases Prefrontal Cortex Inhibitory Postsynaptic Currents following Traumatic Brain Injury","volume":"8","author":"Runyan","year":"2021","journal-title":"eNeuro"},{"key":"10.1016\/j.bbi.2026.106293_b0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2019.116391","article-title":"Music enhances structural maturation of emotional processing neural pathways in very preterm infants","volume":"207","author":"Sa de Almeida","year":"2020","journal-title":"NeuroImage"},{"issue":"1","key":"10.1016\/j.bbi.2026.106293_b0270","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.bbr.2005.01.011","article-title":"Basal forebrain cholinergic lesions in 7-day-old rats alter ultrasound vocalisations and homing behaviour","volume":"161","author":"Scattoni","year":"2005","journal-title":"Behavioural Brain Research"},{"issue":"7","key":"10.1016\/j.bbi.2026.106293_b0275","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2019","article-title":"Fiji: an open-source platform for biological-image analysis","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nature Methods"},{"issue":"7","key":"10.1016\/j.bbi.2026.106293_b0280","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1002\/glia.24148","article-title":"The roles of microglia and astrocytes in phagocytosis and myelination: Insights from the cuprizone model of multiple sclerosis","volume":"70","author":"Sen","year":"2022","journal-title":"Glia"},{"key":"10.1016\/j.bbi.2026.106293_b0285","doi-asserted-by":"crossref","unstructured":"Serhan, C. N., Jain, A., Marleau, S., Clish, C., Kantarci, A., Behbehani, B., Colgan, S. P., Stahl, G. L., Merched, A., Petasis, N. A., Chan, L., & Van Dyke, T. E. (2003). Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators. Journal of Immunology (Baltimore, Md.: 1950), 171(12), 6856\u20136865. https:\/\/doi.org\/10.4049\/jimmunol.171.12.6856.","DOI":"10.4049\/jimmunol.171.12.6856"},{"issue":"6","key":"10.1016\/j.bbi.2026.106293_b0290","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/j.celrep.2017.04.047","article-title":"Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia via P2Y1 Receptor Downregulation","volume":"19","author":"Shinozaki","year":"2017","journal-title":"Cell Reports"},{"key":"10.1016\/j.bbi.2026.106293_b0295","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.1012459","article-title":"Negative regulator NLRC3: its potential role and regulatory mechanism in immune response and immune-related diseases","volume":"13","author":"Sun","year":"2022","journal-title":"Frontiers in Immunology"},{"key":"10.1016\/j.bbi.2026.106293_b0300","doi-asserted-by":"crossref","DOI":"10.1016\/j.peptides.2020.170398","article-title":"Chronic Oxytocin treatment has long lasting therapeutic potential in a rat model of neonatal hypercapnic-hypoxia injury, through enhanced GABAergic signaling and by reducing hippocampal gliosis with its anti-inflammatory feature","volume":"135","author":"S\u00fcnnet\u00e7i","year":"2021","journal-title":"Peptides"},{"issue":"4","key":"10.1016\/j.bbi.2026.106293_b0305","doi-asserted-by":"crossref","DOI":"10.1111\/jne.12364","article-title":"Sex differences in the Embryonic Development of the Central Oxytocin System in mice","volume":"28","author":"Tamborski","year":"2016","journal-title":"Journal of Neuroendocrinology"},{"issue":"11","key":"10.1016\/j.bbi.2026.106293_b0310","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0294236","article-title":"SRplot: a free online platform for data visualization and graphing","volume":"18","author":"Tang","year":"2023","journal-title":"PloS One"},{"issue":"24","key":"10.1016\/j.bbi.2026.106293_b0315","doi-asserted-by":"crossref","first-page":"7886","DOI":"10.1523\/JNEUROSCI.0087-09.2009","article-title":"The Nitric Oxide\u2013cGMP Pathway Controls the Directional Polarity of Growth Cone Guidance via Modulating Cytosolic Ca2+ Signals","volume":"29","author":"Tojima","year":"2009","journal-title":"The Journal of Neuroscience"},{"key":"10.1016\/j.bbi.2026.106293_b0320","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2023.120470","article-title":"Dynamic Functional Connectivity in Pediatric Mild Traumatic Brain Injury","volume":"285","author":"van der Horn","year":"2024","journal-title":"NeuroImage"},{"issue":"12","key":"10.1016\/j.bbi.2026.106293_b0325","doi-asserted-by":"crossref","first-page":"3806","DOI":"10.1093\/brain\/awz319","article-title":"Decreased microglial Wnt\/\u03b2-catenin signalling drives microglial pro-inflammatory activation in the developing brain","volume":"142","author":"Van Steenwinckel","year":"2019","journal-title":"Brain: A Journal of Neurology"},{"issue":"1","key":"10.1016\/j.bbi.2026.106293_b0330","doi-asserted-by":"crossref","first-page":"16492","DOI":"10.1038\/s41598-017-16797-1","article-title":"A quantitative method for microstructural analysis of myelinated axons in the injured rodent brain","volume":"7","author":"van Tilborg","year":"2017","journal-title":"Scientific Reports"},{"issue":"5","key":"10.1016\/j.bbi.2026.106293_b0335","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1002\/mrm.26059","article-title":"Diffusion MRI noise mapping using random matrix theory","volume":"76","author":"Veraart","year":"2016","journal-title":"Magnetic Resonance in Medicine"},{"key":"10.1016\/j.bbi.2026.106293_b0340","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.neuroimage.2013.05.028","article-title":"Weighted linear least squares estimation of diffusion MRI parameters: Strengths, limitations, and pitfalls","volume":"81","author":"Veraart","year":"2013","journal-title":"NeuroImage"},{"issue":"9","key":"10.1016\/j.bbi.2026.106293_b0345","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1002\/glia.23171","article-title":"Sexual dimorphism in the inflammatory response to traumatic brain injury","volume":"65","author":"Villapol","year":"2017","journal-title":"Glia"},{"issue":"3","key":"10.1016\/j.bbi.2026.106293_b0350","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1093\/scan\/nsw150","article-title":"Oxytocin receptor gene variations predict neural and behavioral response to oxytocin in autism","volume":"12","author":"Watanabe","year":"2017","journal-title":"Social Cognitive and Affective Neuroscience"},{"issue":"5","key":"10.1016\/j.bbi.2026.106293_b0355","doi-asserted-by":"crossref","first-page":"797","DOI":"10.3727\/096368916X690403","article-title":"Intracranial Transplantation of Hypoxia-Preconditioned iPSC-derived Neural Progenitor Cells Alleviates Neuropsychiatric Defects after Traumatic Brain Injury in Juvenile Rats","volume":"25","author":"Wei","year":"2016","journal-title":"Cell Transplantation"},{"issue":"7","key":"10.1016\/j.bbi.2026.106293_b0360","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1161\/STROKEAHA.123.043391","article-title":"Oxytocin Improves Intracerebral Hemorrhage Outcomes by Suppressing Neuronal Pyroptosis and Mitochondrial Fission","volume":"54","author":"Yang","year":"2023","journal-title":"Stroke"},{"key":"10.1016\/j.bbi.2026.106293_b0365","doi-asserted-by":"crossref","DOI":"10.1007\/s12035-025-05061-7","article-title":"Oxytocin Regulated Neuroinflammation through OTR\/Mitochondria Mediated Pathway to Improve Hypoxia-Induced Brain Injury","author":"Yang","year":"2025","journal-title":"Molecular Neurobiology"},{"issue":"1","key":"10.1016\/j.bbi.2026.106293_b0370","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1186\/1471-2105-13-134","article-title":"Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction","volume":"13","author":"Ye","year":"2012","journal-title":"BMC Bioinformatics"},{"issue":"1","key":"10.1016\/j.bbi.2026.106293_b0375","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/s12974-016-0541-7","article-title":"Oxytocin inhibits lipopolysaccharide-induced inflammation in microglial cells and attenuates microglial activation in lipopolysaccharide-treated mice","volume":"13","author":"Yuan","year":"2016","journal-title":"Journal of Neuroinflammation"},{"issue":"Suppl 1","key":"10.1016\/j.bbi.2026.106293_b0380","doi-asserted-by":"crossref","first-page":"L15","DOI":"10.1186\/1750-1326-7-S1-L15","article-title":"Suppression of neuroinflammation by the dopamine receptor D2 via alphaB-crystallin","volume":"7","author":"Zhou","year":"2012","journal-title":"Molecular Neurodegeneration"},{"issue":"11","key":"10.1016\/j.bbi.2026.106293_b0385","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1038\/s41418-018-0127-2","article-title":"Dopamine D2 receptor restricts astrocytic NLRP3 inflammasome activation via enhancing the interaction of \u03b2-arrestin2 and NLRP3","volume":"25","author":"Zhu","year":"2018","journal-title":"Cell Death and Differentiation"}],"container-title":["Brain, Behavior, and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159126000413?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159126000413?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T23:36:14Z","timestamp":1789083374000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889159126000413"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":77,"alternative-id":["S0889159126000413"],"URL":"https:\/\/doi.org\/10.1016\/j.bbi.2026.106293","relation":{},"ISSN":["0889-1591"],"issn-type":[{"value":"0889-1591","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chemogenetic activation of oxytocinergic neurons modulates acute neuroinflammation and improves brain development after pediatric traumatic brain injury","name":"articletitle","label":"Article Title"},{"value":"Brain, Behavior, and Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbi.2026.106293","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"106293"}}