{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T23:54:44Z","timestamp":1790898884520,"version":"4.1.0"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100010029","name":"Taishan Scholar Foundation of Shandong Province","doi-asserted-by":"publisher","award":["NO.tsqn202211375"],"award-info":[{"award-number":["NO.tsqn202211375"]}],"id":[{"id":"10.13039\/501100010029","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain, Behavior, and Immunity"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.bbi.2026.106978","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T15:30:52Z","timestamp":1787931052000},"page":"106978","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Peripheral inflammation offers significant but limited explanation for the association between sleep and cognition health: evidence from two longitudinal studies"],"prefix":"10.1016","volume":"139","author":[{"given":"Liang-Jie","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang-Yu","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan-Juan","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen-Chen","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3310-5875","authenticated-orcid":false,"given":"Wei","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbi.2026.106978_b0005","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.psyneuen.2016.02.021","article-title":"Recurrent short sleep, chronic insomnia symptoms and salivary cortisol: a 10-year follow-up in the Whitehall II study","volume":"68","author":"Abell","year":"2016","journal-title":"Psychoneuroendocrinology"},{"issue":"11","key":"10.1016\/j.bbi.2026.106978_b0010","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26115157","article-title":"Neutrophil-to-lymphocyte ratio in the Alzheimer\u2019s disease continuum","volume":"26","author":"Aprile","year":"2025","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.bbi.2026.106978_b0015","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsaa164","article-title":"Systemic inflammation as a moderator between sleep and incident dementia","volume":"44","author":"Baril","year":"2021","journal-title":"Sleep"},{"issue":"10","key":"10.1016\/j.bbi.2026.106978_b0020","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1038\/s41574-018-0048-7","article-title":"Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications","volume":"14","author":"Biessels","year":"2018","journal-title":"Nat. Rev. Endocrinol."},{"issue":"6","key":"10.1016\/j.bbi.2026.106978_b0025","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/nrneurol.2011.60","article-title":"Depression and risk of developing dementia","volume":"7","author":"Byers","year":"2011","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.bbi.2026.106978_b0030","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1087571","article-title":"A meta-analysis investigating the relationship between inflammation in autoimmune disease, elevated CRP, and the risk of dementia","volume":"14","author":"Cooper","year":"2023","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.bbi.2026.106978_b0035","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1007\/s11682-012-9186-z","article-title":"Development and assessment of a composite score for memory in the Alzheimer\u2019s disease neuroimaging initiative (ADNI)","volume":"6","author":"Crane","year":"2012","journal-title":"Brain Imaging Behav."},{"issue":"18","key":"10.1016\/j.bbi.2026.106978_b0040","doi-asserted-by":"crossref","first-page":"3544","DOI":"10.1111\/bph.14586","article-title":"Neutralization of IL-17 rescues amyloid-\u03b2-induced neuroinflammation and memory impairment","volume":"176","author":"Cristiano","year":"2019","journal-title":"Br. J. Pharmacol."},{"issue":"5","key":"10.1016\/j.bbi.2026.106978_b0045","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1192\/bjp.bp.112.118307","article-title":"Late-life depression and risk of vascular dementia and Alzheimer\u2019s disease: systematic review and meta-analysis of community-based cohort studies","volume":"202","author":"Diniz","year":"2018","journal-title":"Br. J. Psychiatry"},{"issue":"2","key":"10.1016\/j.bbi.2026.106978_b0050","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1002\/ana.25159","article-title":"Neutrophil hyperactivation correlates with Alzheimer\u2019s disease progression","volume":"83","author":"Dong","year":"2018","journal-title":"Ann. Neurol."},{"issue":"12","key":"10.1016\/j.bbi.2026.106978_b0055","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1017\/S104161022400070X","article-title":"Sleep-related measurements to assess sleep disturbances among people living with dementia in nursing homes: a systematic review","volume":"36","author":"D\u00f6rner","year":"2024","journal-title":"Int. Psychogeriatr."},{"issue":"3","key":"10.1016\/j.bbi.2026.106978_b0060","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/s00408-016-9869-0","article-title":"Snoring as a determinant factor of oxidative stress in the airway of patients with obstructive sleep Apnea","volume":"194","author":"Fernandez Alvarez","year":"2016","journal-title":"Lung"},{"issue":"5","key":"10.1016\/j.bbi.2026.106978_b0065","doi-asserted-by":"crossref","DOI":"10.1111\/acel.13610","article-title":"Role of sleep quality in the acceleration of biological aging and its potential for preventive interaction on air pollution insults: Findings from the UK Biobank cohort","volume":"21","author":"Gao","year":"2022","journal-title":"Aging Cell"},{"issue":"6","key":"10.1016\/j.bbi.2026.106978_b0070","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1111\/jdi.12087","article-title":"Diabetes mellitus and risk of dementia: a meta\u2010analysis of prospective observational studies","volume":"4","author":"Gudala","year":"2013","journal-title":"J. Diabetes Invest."},{"issue":"3","key":"10.1016\/j.bbi.2026.106978_b0075","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.cell.2024.11.027","article-title":"Norepinephrine-mediated slow vasomotion drives glymphatic clearance during sleep","volume":"188","author":"Hauglund","year":"2025","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.bbi.2026.106978_b0080","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s13195-022-00968-y","article-title":"Association of peripheral immunity with cognition, neuroimaging, and Alzheimer\u2019s pathology","volume":"14","author":"Hou","year":"2022","journal-title":"Alzheimers Res. Ther."},{"issue":"1","key":"10.1016\/j.bbi.2026.106978_b0085","doi-asserted-by":"crossref","first-page":"117","DOI":"10.14283\/jpad.2023.78","article-title":"Relationships of hypnotics with incident dementia and Alzheimer\u2019s disease: a longitudinal study and meta-analysis","volume":"11","author":"Hou","year":"2024","journal-title":"J. Prev Alzheimers Dis."},{"key":"10.1016\/j.bbi.2026.106978_b0090","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.jad.2021.02.013","article-title":"Sleep, inflammation and cognitive function in middle-aged and older adults: a population-based study","volume":"284","author":"Hu","year":"2021","journal-title":"J. Affect. Disord."},{"issue":"1","key":"10.1016\/j.bbi.2026.106978_b0095","doi-asserted-by":"crossref","DOI":"10.1186\/s13024-024-00706-y","article-title":"Unraveling the dual nature of brain CD8+ T cells in Alzheimer\u2019s disease","volume":"19","author":"Hu","year":"2024","journal-title":"Mol. Neurodegener."},{"issue":"1","key":"10.1016\/j.bbi.2026.106978_b0100","doi-asserted-by":"crossref","DOI":"10.1186\/s12916-025-04255-z","article-title":"Sleep quality, APOE \u03b54, and Alzheimer\u2019s disease: associations from two prospective cohort studies and mechanisms by plasma proteomic analysis","volume":"23","author":"Huang","year":"2025","journal-title":"BMC Med."},{"key":"10.1016\/j.bbi.2026.106978_b0105","article-title":"Association of peripheral blood cell profile with Alzheimer\u2019s disease: a meta-analysis","volume":"14","author":"Huang","year":"2022","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.bbi.2026.106978_b0110","article-title":"Association of peripheral blood cell profile with Alzheimer\u2019s disease: a meta-analysis","volume":"14","author":"Huang","year":"2022","journal-title":"Front. Aging Neurosci."},{"issue":"1","key":"10.1016\/j.bbi.2026.106978_b0115","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1038\/npp.2016.148","article-title":"Sleep health: reciprocal regulation of sleep and innate immunity","volume":"42","author":"Irwin","year":"2016","journal-title":"Neuropsychopharmacology"},{"issue":"16","key":"10.1016\/j.bbi.2026.106978_b0120","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1001\/archinte.166.16.1756","article-title":"Sleep deprivation and activation of morning levels of cellular and genomic markers of inflammation","volume":"166","author":"Irwin","year":"2006","journal-title":"Arch. Intern. Med."},{"issue":"6","key":"10.1016\/j.bbi.2026.106978_b0125","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.biopsych.2008.05.004","article-title":"Sleep loss activates cellular inflammatory signaling","volume":"64","author":"Irwin","year":"2008","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbi.2026.106978_b0130","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.bbi.2014.09.017","article-title":"Sleep loss activates cellular inflammation and signal transducer and activator of transcription (STAT) family proteins in humans","volume":"47","author":"Irwin","year":"2015","journal-title":"Brain Behav. Immun."},{"issue":"2","key":"10.1016\/j.bbi.2026.106978_b0135","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1093\/ije\/dyr218","article-title":"Recommendations for presenting analyses of effect modification and interaction","volume":"41","author":"Knol","year":"2012","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.bbi.2026.106978_b0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2024.102514","article-title":"Sleep disorders and risk of Alzheimer\u2019s disease: a two-way road","volume":"101","author":"Lacerda","year":"2024","journal-title":"Ageing Res. Rev."},{"issue":"6","key":"10.1016\/j.bbi.2026.106978_b0145","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1002\/ana.23908","article-title":"Comparing positron emission tomography imaging and cerebrospinal fluid measurements of \u03b2-amyloid","volume":"74","author":"Landau","year":"2013","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.bbi.2026.106978_b0150","doi-asserted-by":"crossref","DOI":"10.2147\/CIA.S74042","article-title":"Link between type 2 diabetes and Alzheimer\u2019s disease: from epidemiology to mechanism and treatment","author":"Li","year":"2015","journal-title":"Clin. Interv. Aging"},{"key":"10.1016\/j.bbi.2026.106978_b0155","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2020.00279","article-title":"Pathways connecting late-life depression and dementia","volume":"11","author":"Linnemann","year":"2020","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.bbi.2026.106978_b0160","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.bbi.2023.02.009","article-title":"Lung function and risk of incident dementia: a prospective cohort study of 431,834 individuals","volume":"109","author":"Ma","year":"2023","journal-title":"Brain Behav. Immun."},{"issue":"6","key":"10.1016\/j.bbi.2026.106978_b0165","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0305322","article-title":"Neutrophil to lymphocyte ratio in Alzheimer\u2019s disease: a systematic review and meta-analysis","volume":"19","author":"Mohammadi","year":"2024","journal-title":"PLoS One"},{"issue":"6512","key":"10.1016\/j.bbi.2026.106978_b0170","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1126\/science.abb8739","article-title":"Glymphatic failure as a final common pathway to dementia","volume":"370","author":"Nedergaard","year":"2020","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.bbi.2026.106978_b0175","doi-asserted-by":"crossref","DOI":"10.1098\/rsfs.2019.0092","article-title":"Sleep deprivation and stress: a reciprocal relationship","volume":"10","author":"Nollet","year":"2020","journal-title":"Interface Focus"},{"key":"10.1016\/j.bbi.2026.106978_b0180","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2018.01213","article-title":"Imbalance of circulating Th17 and regulatory T cells in Alzheimer\u2019s disease: a case control study","volume":"9","author":"Oberstein","year":"2018","journal-title":"Front. Immunol."},{"issue":"5","key":"10.1016\/j.bbi.2026.106978_b0185","doi-asserted-by":"crossref","DOI":"10.1001\/archpsyc.63.5.530","article-title":"Depression and risk for Alzheimer disease","volume":"63","author":"Ownby","year":"2006","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.bbi.2026.106978_b0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.smim.2022.101594","article-title":"APOE mediated neuroinflammation and neurodegeneration in Alzheimer\u2019s disease","volume":"59","author":"Parhizkar","year":"2022","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.bbi.2026.106978_b0195","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.02231","article-title":"Mimicry of central-peripheral immunity in Alzheimer\u2019s disease and discovery of neurodegenerative roles in neutrophil","volume":"10","author":"Park","year":"2019","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.bbi.2026.106978_b0200","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3233\/JAD-2011-111349","article-title":"Performance of a\u03b21-40, a\u03b21-42, total tau, and phosphorylated tau as predictors of dementia in a cohort of patients with mild cognitive impairment","volume":"29","author":"Parnetti","year":"2012","journal-title":"J. Alzheimer\u2019s Dis.: JAD"},{"issue":"10","key":"10.1016\/j.bbi.2026.106978_b0205","doi-asserted-by":"crossref","first-page":"2990","DOI":"10.1038\/s41591-024-03122-3","article-title":"Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer\u2019s disease","volume":"30","author":"Rosenzweig","year":"2024","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbi.2026.106978_b0210","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1146\/annurev-immunol-042718-041717","article-title":"Regulatory T cells and human disease","volume":"38","author":"Sakaguchi","year":"2020","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.bbi.2026.106978_b0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.jneuroim.2020.577398","article-title":"The neutrophil-to-lymphocyte ratio in Alzheimer\u2019s disease: current understanding and potential applications","volume":"349","author":"Sayed","year":"2020","journal-title":"J. Neuroimmunol."},{"issue":"1","key":"10.1016\/j.bbi.2026.106978_b0220","doi-asserted-by":"crossref","DOI":"10.1111\/jsr.14288","article-title":"Sleep discrepancy and cognitive function in community-dwelling older adults","volume":"34","author":"Soh","year":"2025","journal-title":"J. Sleep Res."},{"key":"10.1016\/j.bbi.2026.106978_b0225","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2018.00754","article-title":"Role of C-reactive protein at sites of inflammation and infection","volume":"9","author":"Sproston","year":"2018","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.bbi.2026.106978_b0230","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001779","article-title":"UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age","volume":"12","author":"Sudlow","year":"2015","journal-title":"PLoS Med."},{"key":"10.1016\/j.bbi.2026.106978_b0235","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.bbi.2020.05.070","article-title":"CD8+ T-cells infiltrate Alzheimer\u2019s disease brains and regulate neuronal- and synapse-related gene expression in APP-PS1 transgenic mice","volume":"89","author":"Unger","year":"2020","journal-title":"Brain Behav. Immun."},{"issue":"4","key":"10.1016\/j.bbi.2026.106978_b0240","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.smrv.2012.09.005","article-title":"Insomnia with objective short sleep duration: the most biologically severe phenotype of the disorder","volume":"17","author":"Vgontzas","year":"2013","journal-title":"Sleep Med. Rev."},{"issue":"6","key":"10.1016\/j.bbi.2026.106978_b0245","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/s10654-019-00499-1","article-title":"Identifying dementia outcomes in UK Biobank: a validation study of primary care, hospital admissions and mortality data","volume":"34","author":"Wilkinson","year":"2019","journal-title":"Eur. J. Epidemiol."},{"issue":"8","key":"10.1016\/j.bbi.2026.106978_b0250","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1002\/alz.12117","article-title":"Sleep characteristics and cerebrospinal fluid biomarkers of Alzheimer\u2019s disease pathology in cognitively intact older adults: the CABLE study","volume":"16","author":"Xu","year":"2020","journal-title":"Alzheimers Dement."},{"issue":"3","key":"10.1016\/j.bbi.2026.106978_b0255","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1136\/jnnp-2019-321896","article-title":"Sleep problems and risk of all-cause cognitive decline or dementia: an updated systematic review and meta-analysis","volume":"91","author":"Xu","year":"2020","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"4","key":"10.1016\/j.bbi.2026.106978_b0260","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.3233\/JAD-201582","article-title":"Insomnia moderates the relationship between amyloid-\u03b2 and cognitive decline in late-life adults without dementia","volume":"81","author":"Xu","year":"2021","journal-title":"J. Alzheimer\u2019s Dis.: JAD"},{"key":"10.1016\/j.bbi.2026.106978_b0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2019.100944","article-title":"Diabetes mellitus and risks of cognitive impairment and dementia: a systematic review and meta-analysis of 144 prospective studies","volume":"55","author":"Xue","year":"2019","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.bbi.2026.106978_b0270","doi-asserted-by":"crossref","DOI":"10.1016\/j.micres.2022.127292","article-title":"Acute sleep deprivation exacerbates systemic inflammation and psychiatry disorders through gut microbiota dysbiosis and disruption of circadian rhythms","volume":"268","author":"Yang","year":"2023","journal-title":"Microbiol. Res."},{"issue":"11","key":"10.1016\/j.bbi.2026.106978_b0275","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1136\/jnnp-2019-321913","article-title":"Evidence-based prevention of Alzheimer\u2019s disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials","volume":"91","author":"Yu","year":"2020","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"4","key":"10.1016\/j.bbi.2026.106978_b0280","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1038\/s41380-022-01446-5","article-title":"Peripheral immunity is associated with the risk of incident dementia","volume":"27","author":"Zhang","year":"2022","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.bbi.2026.106978_b0285","first-page":"1","article-title":"Oxidative stress and the pathogenesis of Alzheimer\u2019s disease","volume":"2013","author":"Zhao","year":"2013","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"6","key":"10.1016\/j.bbi.2026.106978_b0290","doi-asserted-by":"crossref","DOI":"10.1111\/jsr.13679","article-title":"Acute sleep deprivation increases inflammation and aggravates heart failure after myocardial infarction","volume":"31","author":"Zhu","year":"2022","journal-title":"J. Sleep Res."}],"container-title":["Brain, Behavior, and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159126007269?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889159126007269?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T23:11:47Z","timestamp":1790896307000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889159126007269"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":58,"alternative-id":["S0889159126007269"],"URL":"https:\/\/doi.org\/10.1016\/j.bbi.2026.106978","relation":{},"ISSN":["0889-1591"],"issn-type":[{"value":"0889-1591","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Peripheral inflammation offers significant but limited explanation for the association between sleep and cognition health: evidence from two longitudinal studies","name":"articletitle","label":"Article Title"},{"value":"Brain, Behavior, and Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbi.2026.106978","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"106978"}}