{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T07:21:50Z","timestamp":1792480910513,"version":"4.5.0"},"reference-count":76,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T00:00:00Z","timestamp":1637712000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000006","name":"Office of Naval Research","doi-asserted-by":"publisher","award":["N00014-16-1-2868"],"award-info":[{"award-number":["N00014-16-1-2868"]}],"id":[{"id":"10.13039\/100000006","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain, Behavior, &amp; Immunity - Health"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.bbih.2021.100398","type":"journal-article","created":{"date-parts":[[2021,11,27]],"date-time":"2021-11-27T11:42:20Z","timestamp":1638013340000},"page":"100398","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["Astrocyte-derived microparticles initiate a neuroinflammatory cycle due to carbon monoxide poisoning"],"prefix":"10.1016","volume":"18","author":[{"given":"Deepa","family":"Ruhela","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veena M.","family":"Bhopale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8091-9978","authenticated-orcid":false,"given":"Sudhakar","family":"Kalakonda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen R.","family":"Thom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbih.2021.100398_bib1","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.29738","article-title":"Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI","volume":"6","author":"Absinta","year":"2017","journal-title":"Elife"},{"key":"10.1016\/j.bbih.2021.100398_bib2","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1038\/s41419-020-02985-x","article-title":"NLRP3 inflammasome in endothelial dysfunction","volume":"11","author":"Bai","year":"2020","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.bbih.2021.100398_bib3","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.mehy.2017.05.010","article-title":"Demyelinating diseases as a result of cerebral edema?","volume":"104","author":"Barz","year":"2017","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.bbih.2021.100398_bib4","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1042\/bj3260539","article-title":"P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain","volume":"326","author":"Beaulieu","year":"1997","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbih.2021.100398_bib5","doi-asserted-by":"crossref","first-page":"625","DOI":"10.3174\/ajnr.A3489","article-title":"The role of MR imaging in assessment of brain damage from carbon monoxide poisoning: a review of the literature","volume":"35","author":"Beppu","year":"2014","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.bbih.2021.100398_bib6","first-page":"1698","article-title":"Fractional anisotropy in the centrum semiovale as a quantitative indicator of cerebral white matter damage in the subacute phase in patients with carbon monoxide poisoning: correlation with the concentration of myelin basic protein in cerebrospinal fluid","volume":"259","author":"Beppu","year":"2012","journal-title":"J.\u00a0Neurol."},{"key":"10.1016\/j.bbih.2021.100398_bib7","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.freeradbiomed.2016.10.010","article-title":"Microparticle formation by platelets exposed to high gas pressures \u2013 an oxidative stress response","volume":"101","author":"Bhullar","year":"2016","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bbih.2021.100398_bib8","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/nrn2038","article-title":"Microglia-mediated neurotoxicity: uncovering the molecular mechanisms","volume":"8","author":"Block","year":"2007","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.bbih.2021.100398_bib9","first-page":"1309","article-title":"Carbon monoxide-related deaths-United States, 1999-2004","volume":"56","author":"CDC","year":"2007","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"10.1016\/j.bbih.2021.100398_bib10","first-page":"2504","article-title":"The class B scavenger receptor CD36 mediates free radical production and tissue injury in cerebral ischemia","volume":"25","author":"Cho","year":"2005","journal-title":"J.\u00a0Neurochem."},{"key":"10.1016\/j.bbih.2021.100398_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0108553","article-title":"Gene expression during the generation and activation of mouse neutrophils: implication of novel functional and regulatory pathways","volume":"9","author":"Ericson","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.bbih.2021.100398_bib12","doi-asserted-by":"crossref","first-page":"2012","DOI":"10.1016\/j.biocel.2007.03.012","article-title":"CD36: implications in cardiovascular disease","volume":"39","author":"Febbraio","year":"2007","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.bbih.2021.100398_bib13","doi-asserted-by":"crossref","first-page":"14783","DOI":"10.1523\/JNEUROSCI.2980-15.2015","article-title":"Endothelial CD36 contributes to postischemic brain injury by promoting neutrophil activation via CSF3","volume":"35","author":"Garcia-Bonilla","year":"2015","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.bbih.2021.100398_bib14","first-page":"1934","article-title":"Platelet CD36 mediates interactions with endothelial cell-derived microparticles and contributes to thrombosis in vivo","volume":"118","author":"Ghosh","year":"2008","journal-title":"J.\u00a0Clin. Invest."},{"issue":"Suppl. l","key":"10.1016\/j.bbih.2021.100398_bib15","doi-asserted-by":"crossref","first-page":"S81","DOI":"10.1016\/S0092-8674(02)00703-1","article-title":"Missing pieces in the NF-kappaB puzzle","volume":"109","author":"Ghosh","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.bbih.2021.100398_bib16","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1182\/blood.V80.5.1105.1105","article-title":"Membrane glycoprotein CD36: a review of its roles in adherence, signal transduction, and transfusion medicine","volume":"80","author":"Greenwalt","year":"1992","journal-title":"Blood"},{"key":"10.1016\/j.bbih.2021.100398_bib17","first-page":"1768","article-title":"U.S. mortality due to carbon monoxide poisoning, 1999-2014: accidental and intentional deaths","volume":"13","author":"Hampson","year":"2016","journal-title":"Ann. Am Thorac. Soc."},{"key":"10.1016\/j.bbih.2021.100398_bib18","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1164\/rccm.201207-1284CI","article-title":"Practice recommendations in the diagnosis, management, and prevention of carbon monoxide poisoning","volume":"186","author":"Hampson","year":"2012","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.bbih.2021.100398_bib19","first-page":"667","article-title":"Cost of accidental carbon monoxide poisoning: a preventable expense","volume":"3","author":"Hampson","year":"2016","journal-title":"Prev. Med. Rep."},{"key":"10.1016\/j.bbih.2021.100398_bib20","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.toxlet.2007.02.006","article-title":"Xanthine oxidoreductase and neurological sequelae of carbon monoxide poisoning","volume":"170","author":"Han","year":"2007","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.bbih.2021.100398_bib21","doi-asserted-by":"crossref","first-page":"9894","DOI":"10.1073\/pnas.1706942114","article-title":"Interstitial solute transport in 3D reconstructed neuropil occurs by diffusion rather than bulk flow","volume":"114","author":"Holter","year":"2017","journal-title":"Proc. Natl. Acad. Sci. Unit. States Am."},{"key":"10.1016\/j.bbih.2021.100398_bib22","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.1093\/hmg\/ddt036","article-title":"A\u00a0critical role of astrocyte-mediated nuclear factor-kB-dependent inflammation in Huntington's disease","volume":"22","author":"Hsiao","year":"2013","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bbih.2021.100398_bib23","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/j.ajem.2008.07.009","article-title":"The early elevation of interleukin 6 concentration in cerebrospinal fluid and delayed encephalopathy of carbon monoxide poisoning","volume":"27","author":"Ide","year":"2009","journal-title":"Am. J. Emerg. Med."},{"key":"10.1016\/j.bbih.2021.100398_bib24","doi-asserted-by":"crossref","first-page":"147ra111","DOI":"10.1126\/scitranslmed.3003748","article-title":"A\u00a0paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid \u03b2","volume":"4","author":"Iliff","year":"2012","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.bbih.2021.100398_bib25","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1172\/JCI118667","article-title":"Nitric oxide production and perivascular tyrosine nitration in brain after carbon monoxide poisoning in the rat","volume":"97","author":"Ischiropoulos","year":"1996","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.bbih.2021.100398_bib26","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1001\/jamaneurol.2017.4618","article-title":"Acute brain lesions on magnetic resonance imaging and delayed neurological sequelae in carbon monoxide poisoning","volume":"75","author":"Jeon","year":"2018","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.bbih.2021.100398_bib27","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.ajem.2006.06.019","article-title":"Recurrent myelin basic protein elevation in cerebrospinal fluid as a predictive marker of delayed encephalopathy after carbon monoxide poisoning","volume":"25","author":"Kamijo","year":"2007","journal-title":"Am. J. Emerg. Med."},{"key":"10.1016\/j.bbih.2021.100398_bib28","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/s41420-017-0023-4","article-title":"Thrombospondin-1 protects against A\u03b2-induced mitochondrial fragmentation and dysfunction in hippocampal cells","volume":"4","author":"Kang","year":"2018","journal-title":"Cell Death Discovery"},{"key":"10.1016\/j.bbih.2021.100398_bib29","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1002\/ana.23569","article-title":"CD36 in the periphery and brain synergizes in stroke injury in hyperlipidemia","volume":"71","author":"Kim","year":"2012","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.bbih.2021.100398_bib30","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1111\/cns.12326","article-title":"Targeting CD36-mediated inflammation reduces acute brain injury in transient, but not permanent, ischemic stroke","volume":"21","author":"Kim","year":"2015","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.bbih.2021.100398_bib31","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1182\/blood-2010-05-284513","article-title":"Myeloperoxidase attracts neutrophils by physical forces","volume":"117","author":"Klinke","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.bbih.2021.100398_bib32","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1111\/j.1463-1326.2011.01402.x","article-title":"JSH-23 targets nuclear factor-kappa B and reverses various deficits in experimental diabetic neuropathy: effect on neuroinflammation and antioxidant defence","volume":"13","author":"Kumar","year":"2011","journal-title":"Diabetes Obes. Metabol."},{"issue":"47","key":"10.1016\/j.bbih.2021.100398_bib33","first-page":"1","article-title":"Microglial-derived microparticles mediate neuroinflammation after traumatic brain injury","volume":"14","author":"Kumar","year":"2017","journal-title":"J.\u00a0Neuroinflammation"},{"key":"10.1016\/j.bbih.2021.100398_bib34","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1523\/JNEUROSCI.5205-07.2008","article-title":"Nuclear factor-kB activation and postischemic inflammation are suppressed in CD36-null mice after middle cerebral artery occlusion","volume":"28","author":"Kunz","year":"2008","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.bbih.2021.100398_bib35","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.jns.2015.12.006","article-title":"Altered white matter metabolism in delayed neurologic sequelae after carbon monoxide poisoning: a proton magnetic resonance spectroscopic study","volume":"360","author":"Kuroda","year":"2016","journal-title":"J.\u00a0Neurol. Sci."},{"key":"10.1016\/j.bbih.2021.100398_bib36","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1096\/fj.09-150573","article-title":"Thrombospondin 1\u2013a key astrocyte-derived neurogenic factor","volume":"24","author":"Lu","year":"2010","journal-title":"Faseb. J."},{"key":"10.1016\/j.bbih.2021.100398_bib37","first-page":"292","article-title":"Residues F16-G33 and A784-N823 within platelet thrombospondin-1 play a major role in binding human neutrophils: evaluation by two novel binding assays","volume":"136","author":"Majluf-Cruz","year":"2000","journal-title":"J.\u00a0Lab. Clin. Med."},{"key":"10.1016\/j.bbih.2021.100398_bib38","doi-asserted-by":"crossref","first-page":"7090","DOI":"10.1158\/0008-5472.CAN-08-0643","article-title":"Thrombospondin 1 promotes tumor macrophage recruitment and enhances tumor cell cytotoxicity of differentiated U937 cells","volume":"68","author":"Martin-Manso","year":"2000","journal-title":"Cancer Res."},{"key":"10.1016\/j.bbih.2021.100398_bib39","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1177\/0960327119891214","article-title":"Worldwide epidemiology of carbon monoxide poisoning","volume":"39","author":"Mattiuzzi","year":"2020","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.bbih.2021.100398_bib40","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1161\/CIRCRESAHA.110.226456","article-title":"Microparticles: protagonists of a novel communication network for intercellular information exchange","volume":"107","author":"Mause","year":"2010","journal-title":"Circ. Res."},{"key":"10.1016\/j.bbih.2021.100398_bib41","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1084\/jem.20182191","article-title":"Fyn kinase regulates misfolded \u03b1-synuclein uptake and NLRP3 inflammasome activation in microglia","volume":"216","author":"Panicker","year":"2019","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.bbih.2021.100398_bib42","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/S1474-4422(18)30318-1","article-title":"The glymphatic pathway in neurological disorders","volume":"17","author":"Rasmussen","year":"2018","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.bbih.2021.100398_bib43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0300-483X(99)00217-6","article-title":"Carbon monoxide poisoning--a public health perspective","volume":"145","author":"Raub","year":"2000","journal-title":"Toxicology"},{"key":"10.1016\/j.bbih.2021.100398_bib44","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1164\/rccm.201606-1275CI","article-title":"Carbon monoxide poisoning: pathogenesis, management, and future directions of therapy","volume":"195","author":"Rose","year":"2017","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.bbih.2021.100398_bib45","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.bbi.2020.01.017","article-title":"Blood-borne and brain-derived microparticles in morphine-induced anti-nociceptive tolerance","volume":"87","author":"Ruhela","year":"2020","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbih.2021.100398_bib46","doi-asserted-by":"crossref","first-page":"30353","DOI":"10.1074\/jbc.274.43.30353","article-title":"IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain","volume":"274","author":"Sakurai","year":"1999","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbih.2021.100398_bib47","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1002\/cbic.200400144","article-title":"NF-kappaB: a multifaceted transcription factor regulated at several levels","volume":"5","author":"Schmitz","year":"2004","journal-title":"Chembiochem"},{"key":"10.1016\/j.bbih.2021.100398_bib48","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.febslet.2004.06.056","article-title":"Inhibitory action of novel aromatic diamine compound on lipopolysaccharide-induced nuclear translocation of NF-kB without affecting IkB degradation","volume":"571","author":"Shin","year":"2004","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbih.2021.100398_bib49","doi-asserted-by":"crossref","first-page":"re3","DOI":"10.1126\/scisignal.272re3","article-title":"CD36, a scavenger receptor involved in immunity, metabolism, angiogenesis, and behavior","volume":"2","author":"Silverstein","year":"2009","journal-title":"Sci. Signal."},{"key":"10.1016\/j.bbih.2021.100398_bib50","doi-asserted-by":"crossref","first-page":"2886","DOI":"10.4049\/jimmunol.1601810","article-title":"Neutrophil microparticles deliver active myeloperoxidase to injured mucosa to inhibit epithelial wound healing","volume":"198","author":"Slater","year":"2017","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.bbih.2021.100398_bib51","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s00401-009-0619-8","article-title":"Astrocytes: biology and pathology","volume":"119","author":"Sofroniew","year":"2010","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.bbih.2021.100398_bib52","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3233\/NRE-2010-0536","article-title":"The syndrome of delayed post-hypoxic leukoencephalopathy","volume":"26","author":"Sprecher","year":"2010","journal-title":"NeuroRehabilitation"},{"key":"10.1016\/j.bbih.2021.100398_bib53","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1152\/jappl.1990.68.3.997","article-title":"Carbon monoxide-mediated brain lipid peroxidation in the rat","volume":"68","author":"Thom","year":"1990","journal-title":"J.\u00a0Appl. Physiol."},{"key":"10.1016\/j.bbih.2021.100398_bib54","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1152\/jappl.1992.73.4.1584","article-title":"Dehydrogenase conversion to oxidase and lipid peroxidation in brain after carbon monoxide poisoning","volume":"73","author":"Thom","year":"1992","journal-title":"J.\u00a0Appl. Physiol."},{"key":"10.1016\/j.bbih.2021.100398_bib55","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1006\/taap.1993.1242","article-title":"Leukocytes in carbon monoxide-mediated brain oxidative injury","volume":"123","author":"Thom","year":"1993","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.bbih.2021.100398_bib56","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1152\/japplphysiol.00380.2015","article-title":"Association of microparticles and neutrophil activation with decompression sickness","volume":"119","author":"Thom","year":"2015","journal-title":"J.\u00a0Appl. Physiol."},{"key":"10.1016\/j.bbih.2021.100398_bib57","doi-asserted-by":"crossref","first-page":"13660","DOI":"10.1073\/pnas.0405642101","article-title":"Delayed neuropathology after carbon monoxide poisoning is immune-mediated","volume":"101","author":"Thom","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbih.2021.100398_bib58","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1164\/rccm.200604-557OC","article-title":"Intravascular neutrophil activation due to carbon monoxide poisoning","volume":"174","author":"Thom","year":"2006","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.bbih.2021.100398_bib59","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.freeradbiomed.2017.03.005","article-title":"Increased carbon dioxide levels stimulate neutrophils to produce microparticles and activate the nucleotide-binding domain-like receptor 3 inflammasome","volume":"106","author":"Thom","year":"2017","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bbih.2021.100398_bib60","doi-asserted-by":"crossref","first-page":"18831","DOI":"10.1074\/jbc.M113.543702","article-title":"Neutrophils generate microparticles during exposure to inert gases due to cytoskeletal oxidative stress","volume":"289","author":"Thom","year":"2014","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbih.2021.100398_bib61","doi-asserted-by":"crossref","first-page":"18312","DOI":"10.1074\/jbc.M117.802629","article-title":"Neutrophil microparticle production and inflammasome activation by hyperglycemia due to cytoskeletal instability","volume":"292","author":"Thom","year":"2017","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbih.2021.100398_bib62","first-page":"H984","article-title":"Role of nitric oxide-derived oxidants in vascular injury from carbon monoxide in the rat","volume":"276","author":"Thom","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.bbih.2021.100398_bib63","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/S0196-0644(95)70261-X","article-title":"Delayed neuropsychologic sequelae after carbon monoxide poisoning: prevention by treatment with hyperbaric oxygen","volume":"25","author":"Thom","year":"1995","journal-title":"Ann. Emerg. Med."},{"key":"10.1016\/j.bbih.2021.100398_bib64","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1152\/japplphysiol.00811.2010","article-title":"Microparticles initiate decompression-induced neutrophil activation and subsequent vascular injuries","volume":"110","author":"Thom","year":"2011","journal-title":"J.\u00a0Appl. Physiol."},{"key":"10.1016\/j.bbih.2021.100398_bib65","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.ajpath.2011.05.002","article-title":"Astrocyte-derived thrombospondin-2 is critical for the repair of the blood-brain barrier","volume":"179","author":"Tian","year":"2011","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.bbih.2021.100398_bib66","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1177\/1971400916689342","article-title":"Advanced neuroimaging of carbon monoxide poisoning","volume":"30","author":"Varrassi","year":"2017","journal-title":"NeuroRadiol. J."},{"key":"10.1016\/j.bbih.2021.100398_bib67","doi-asserted-by":"crossref","first-page":"239","DOI":"10.15252\/embj.201592705","article-title":"Astrocytes as secretory cells of the central nervous system: idiosyncrasies of vesicular secretion","volume":"35","author":"Verkhratsky","year":"2016","journal-title":"EMBO J."},{"issue":"4","key":"10.1016\/j.bbih.2021.100398_bib68","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1007\/s00213-018-5147-6","article-title":"Chronic stress impairs the aquaporin-4-mediated glymphatic transport through glucocorticoid signaling","volume":"236","author":"Wei","year":"2019","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.bbih.2021.100398_bib69","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/j.1750-3639.2008.00133.x","article-title":"Perivascular drainage of amyloid-b peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer's Disease","volume":"18","author":"Weller","year":"2008","journal-title":"Brain Pathol."},{"key":"10.1016\/j.bbih.2021.100398_bib70","doi-asserted-by":"crossref","first-page":"230","DOI":"10.4049\/jimmunol.180.1.230","article-title":"CD36 is differentially expressed on B cell subsets during development and in responses to antigen","volume":"180","author":"Won","year":"2008","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.bbih.2021.100398_bib71","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.taap.2013.09.019","article-title":"Carbon monoxide inhalation increases microparticles causing vascular and CNS dysfunction","volume":"273","author":"Xu","year":"2013","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.bbih.2021.100398_bib72","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1152\/japplphysiol.00745.2013","article-title":"Microparticles generated by decompression stress cause central nervous system injury manifested as neurohypophiseal terminal action potential broadening","volume":"115","author":"Yang","year":"2013","journal-title":"J.\u00a0Appl. Physiol."},{"key":"10.1016\/j.bbih.2021.100398_bib73","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1152\/japplphysiol.00953.2011","article-title":"Microparticle enlargement and altered surface proteins after air decompression are associated with inflammatory vascular injuries","volume":"112","author":"Yang","year":"2012","journal-title":"J.\u00a0Appl. Physiol."},{"key":"10.1016\/j.bbih.2021.100398_bib74","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1111\/jnc.13426","article-title":"Inhibition of myeloperoxidase at the peak of exerimental autoimmune encephalomyelitis restores blood-brain barrier integrity and ameliorates disease severity","volume":"136","author":"Zhang","year":"2016","journal-title":"J.\u00a0Neurochem."},{"key":"10.1016\/j.bbih.2021.100398_bib75","doi-asserted-by":"crossref","first-page":"3368","DOI":"10.1096\/fj.09-131649","article-title":"Thrombospondin-1 modulates vascular endothelial growth factor activity at the receptor level","volume":"23","author":"Zhang","year":"2009","journal-title":"Faseb. J."},{"key":"10.1016\/j.bbih.2021.100398_bib76","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1007\/s13238-017-0414-6","article-title":"Cellular microparticles and pathophysiology of traumatic brain injury","volume":"8","author":"Zhao","year":"2017","journal-title":"Protein Cell"}],"container-title":["Brain, Behavior, &amp; Immunity - Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666354621002015?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666354621002015?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T22:26:37Z","timestamp":1762986397000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666354621002015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":76,"alternative-id":["S2666354621002015"],"URL":"https:\/\/doi.org\/10.1016\/j.bbih.2021.100398","relation":{},"ISSN":["2666-3546"],"issn-type":[{"value":"2666-3546","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Astrocyte-derived microparticles initiate a neuroinflammatory cycle due to carbon monoxide poisoning","name":"articletitle","label":"Article Title"},{"value":"Brain, Behavior, & Immunity - Health","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbih.2021.100398","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100398"}}