{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T01:07:00Z","timestamp":1781658420425,"version":"3.54.5"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T00:00:00Z","timestamp":1751500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH133812"],"award-info":[{"award-number":["R01MH133812"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01MH116948"],"award-info":[{"award-number":["R01MH116948"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["RF1NS114628"],"award-info":[{"award-number":["RF1NS114628"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01MH112180"],"award-info":[{"award-number":["R01MH112180"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain, Behavior, & Immunity - Health"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.bbih.2025.101055","type":"journal-article","created":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T20:46:22Z","timestamp":1751661982000},"page":"101055","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Childhood trauma and inflammatory biomarker effects on cortical thinning in schizophrenia spectrum disorders"],"prefix":"10.1016","volume":"48","author":[{"given":"Samantha","family":"Narvaez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yizhou","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Chiappelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hemalatha","family":"Sampath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alia","family":"Warner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Kochunov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giselli","family":"Scaini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anilkumar","family":"Pillai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Elliot Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.bbih.2025.101055_bib1","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1176\/ajp.147.11.1457","article-title":"Auditory hallucinations and smaller superior temporal gyral volume in schizophrenia","volume":"147","author":"Barta","year":"1990","journal-title":"Am. J. Psychiatr."},{"issue":"5","key":"10.1016\/j.bbih.2025.101055_bib2","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1038\/mp.2015.67","article-title":"Childhood trauma and adulthood inflammation: a meta-analysis of peripheral C-reactive protein, interleukin-6 and tumour necrosis factor-\u03b1","volume":"21","author":"Baumeister","year":"2016","journal-title":"Mol. Psychiatr."},{"key":"10.1016\/j.bbih.2025.101055_bib3","author":"Beharelle"},{"issue":"2","key":"10.1016\/j.bbih.2025.101055_bib4","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0145-2134(02)00541-0","article-title":"Development and validation of a brief screening version of the Childhood Trauma Questionnaire","volume":"27","author":"Bernstein","year":"2003","journal-title":"Child Abuse Neglect"},{"issue":"1","key":"10.1016\/j.bbih.2025.101055_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1162\/08989290051137585","article-title":"Imaging cognition II: an empirical review of 275 PET and fMRI studies","volume":"12","author":"Cabeza","year":"2000","journal-title":"J. Cognit. Neurosci."},{"key":"10.1016\/j.bbih.2025.101055_bib6","article-title":"Associations between child maltreatment and depressive symptoms among Chinese college students: an analysis of sex differences","volume":"12","author":"Chen","year":"2021","journal-title":"Front. Psychiatr."},{"issue":"4","key":"10.1016\/j.bbih.2025.101055_bib7","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2015.43","article-title":"Alterations in frontal white matter neurochemistry and microstructure in schizophrenia: implications for neuroinflammation","volume":"5","author":"Chiappelli","year":"2015","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.bbih.2025.101055_bib8","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.psyneuen.2016.11.021","article-title":"Allostatic load and reduced cortical thickness in schizophrenia","volume":"77","author":"Chiappelli","year":"2017","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.bbih.2025.101055_bib9","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.psyneuen.2015.09.010","article-title":"Disrupted glucocorticoid\u2014immune interactions during stress response in schizophrenia","volume":"63","author":"Chiappelli","year":"2016","journal-title":"Psychoneuroendocrinology"},{"issue":"1","key":"10.1016\/j.bbih.2025.101055_bib10","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/npp.2016.198","article-title":"Psychoneuroimmunology of early-life stress: the hidden wounds of childhood trauma?","volume":"42","author":"Danese","year":"2017","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbih.2025.101055_bib11","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.schres.2018.10.017","article-title":"Inflammatory biomarkers in psychosis and clinical high risk populations","volume":"206","author":"Delaney","year":"2019","journal-title":"Schizophr. Res."},{"issue":"9","key":"10.1016\/j.bbih.2025.101055_bib12","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1017\/S0033291712000074","article-title":"Schizophrenia patients with a history of childhood trauma have a pro-inflammatory phenotype","volume":"42","author":"Dennison","year":"2012","journal-title":"Psychol. Med."},{"issue":"4","key":"10.1016\/j.bbih.2025.101055_bib13","doi-asserted-by":"crossref","first-page":"274","DOI":"10.3109\/07853890009011772","article-title":"Function of C-reactive protein","volume":"32","author":"Du Clos","year":"2000","journal-title":"Ann. Med."},{"issue":"20","key":"10.1016\/j.bbih.2025.101055_bib14","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.200033797","article-title":"Measuring the thickness of the human cerebral cortex from magnetic resonance images","volume":"97","author":"Fischl","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.bbih.2025.101055_bib15","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.bbi.2023.05.015","article-title":"Immune cell subsets in patients with bipolar disorder or schizophrenia with history of childhood maltreatment","volume":"112","author":"Foiselle","year":"2023","journal-title":"Brain Behav. Immun."},{"issue":"3","key":"10.1016\/j.bbih.2025.101055_bib16","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1007\/s00259-021-05529-3","article-title":"Peripheral inflammation is associated with brain SPECT perfusion changes in schizophrenia","volume":"49","author":"Fond","year":"2022","journal-title":"Eur. J. Nucl. Med. Mol. Imag."},{"issue":"1","key":"10.1016\/j.bbih.2025.101055_bib17","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-62051-w","article-title":"New insights into the effects of type and timing of childhood maltreatment on brain morphometry","volume":"14","author":"Grauduszus","year":"2024","journal-title":"Sci. Rep."},{"issue":"3","key":"10.1016\/j.bbih.2025.101055_bib18","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/j.neuroimage.2010.12.045","article-title":"Altered dynamic coupling of lateral occipital complex during visual perception in schizophrenia","volume":"55","author":"Harvey","year":"2011","journal-title":"Neuroimage"},{"issue":"3","key":"10.1016\/j.bbih.2025.101055_bib19","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1093\/schbul\/sbj079","article-title":"Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness","volume":"32","author":"Hennah","year":"2006","journal-title":"Schizophr. Bull."},{"issue":"16","key":"10.1016\/j.bbih.2025.101055_bib20","doi-asserted-by":"crossref","first-page":"9379","DOI":"10.1073\/pnas.96.16.9379","article-title":"Distributed representation of objects in the human ventral visual pathway","volume":"96","author":"Ishai","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.bbih.2025.101055_bib21","doi-asserted-by":"crossref","first-page":"2230","DOI":"10.3389\/fimmu.2018.02230","article-title":"C-reactive protein: higher during acute psychotic episodes and related to cortical thickness in schizophrenia and healthy controls","volume":"9","author":"Jacomb","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbih.2025.101055_bib22","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.bbi.2021.11.014","article-title":"Peripheral complement is increased in schizophrenia and inversely related to cortical thickness","volume":"101","author":"Ji","year":"2022","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbih.2025.101055_bib23","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/978-981-32-9705-0_9","article-title":"The role of early life stress in HPA Axis and anxiety","volume":"1191","author":"Juruena","year":"2020","journal-title":"Adv. Exp. Med. Biol."},{"issue":"1","key":"10.1016\/j.bbih.2025.101055_bib24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/nrdp.2015.67","article-title":"Schizophrenia","volume":"1","author":"Kahn","year":"2015","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.bbih.2025.101055_bib25","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.jad.2023.12.071","article-title":"The effect of inflammation markers on cortical thinning in major depressive disorder: a possible mediator of depression and cortical changes","volume":"348","author":"Kang","year":"2024","journal-title":"J. Affect. Disord."},{"issue":"10","key":"10.1016\/j.bbih.2025.101055_bib26","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1001\/jamapsychiatry.2014.1332","article-title":"Association of serum interleukin 6 and C-reactive protein in childhood with depression and psychosis in young adult life: a population-based longitudinal study","volume":"71","author":"Khandaker","year":"2014","journal-title":"JAMA Psychiatry"},{"issue":"2","key":"10.1016\/j.bbih.2025.101055_bib27","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1017\/S0033291712000736","article-title":"Prenatal maternal infection, neurodevelopment and adult schizophrenia: a systematic review of population-based studies","volume":"43","author":"Khandaker","year":"2013","journal-title":"Psychol. Med."},{"key":"10.1016\/j.bbih.2025.101055_bib28","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.psyneuen.2015.02.007","article-title":"Isolation rearing impaired sensorimotor gating but increased pro-inflammatory cytokines and disrupted metabolic parameters in both sexes of rats","volume":"55","author":"Ko","year":"2015","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.bbih.2025.101055_bib29","author":"Kochunov"},{"issue":"47","key":"10.1016\/j.bbih.2025.101055_bib30","doi-asserted-by":"crossref","first-page":"14980","DOI":"10.1523\/JNEUROSCI.3706-09.2009","article-title":"Superior parietal cortex is critical for the manipulation of information in working memory","volume":"29","author":"Koenigs","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbih.2025.101055_bib31","doi-asserted-by":"crossref","unstructured":"Li, M., Deng, W., Li, Y., Zhao, L., Ma, X., Yu, H., Li, X., Meng, Y., Wang, Q., Du, X., Sham, P. C., Palaniyappan, L., & Li, T. (n.d.). Ameliorative patterns of grey matter in patients with first-episode and treatment-na\u00efve schizophrenia. Psychol. Med., 53(8), 3500\u20133510. https:\/\/doi.org\/10.1017\/S0033291722000058.","DOI":"10.1017\/S0033291722000058"},{"key":"10.1016\/j.bbih.2025.101055_bib32","first-page":"1","article-title":"Temporal changes in brain morphology related to inflammation and schizophrenia: an omnigenic Mendelian randomization study","author":"Liu","year":"2024","journal-title":"Psychol. Med."},{"issue":"1","key":"10.1016\/j.bbih.2025.101055_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41398-022-01936-8","article-title":"An epigenetic association analysis of childhood trauma in psychosis reveals possible overlap with methylation changes associated with PTSD","volume":"12","author":"L\u00f8khammer","year":"2022","journal-title":"Transl. Psychiatry"},{"issue":"1","key":"10.1016\/j.bbih.2025.101055_bib34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41537-023-00415-3","article-title":"Effects of independent versus dependent stressful life events on major symptom domains of schizophrenia","volume":"9","author":"Ma","year":"2023","journal-title":"Schizophrenia"},{"issue":"6","key":"10.1016\/j.bbih.2025.101055_bib35","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.biopsych.2008.04.016","article-title":"Interleukin-6 covaries inversely with hippocampal grey matter volume in middle-aged adults","volume":"64","author":"Marsland","year":"2008","journal-title":"Biol. Psychiatry"},{"issue":"Pt 6","key":"10.1016\/j.bbih.2025.101055_bib36","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1093\/brain\/121.6.1013","article-title":"From sensation to cognition","volume":"121","author":"Mesulam","year":"1998","journal-title":"Brain: J. Neurol."},{"issue":"7","key":"10.1016\/j.bbih.2025.101055_bib37","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.biopsych.2011.04.013","article-title":"Meta-analysis of cytokine alterations in schizophrenia: clinical status and antipsychotic effects","volume":"70","author":"Miller","year":"2011","journal-title":"Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.bbih.2025.101055_bib38","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1037\/0033-2909.133.1.25","article-title":"If it goes up, must it come down? Chronic stress and the hypothalamic-pituitary-adrenocortical axis in humans","volume":"133","author":"Miller","year":"2007","journal-title":"Psychol. Bull."},{"issue":"12","key":"10.1016\/j.bbih.2025.101055_bib39","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.4088\/JCP.10m06745","article-title":"Stress and inflammation reduce brain-derived neurotrophic factor expression in first-episode psychosis: a pathway to smaller hippocampal volume","volume":"72","author":"Mondelli","year":"2011","journal-title":"J. Clin. Psychiatry"},{"issue":"4","key":"10.1016\/j.bbih.2025.101055_bib40","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1111\/eip.12859","article-title":"Role of inflammation in the pathogenesis of schizophrenia: a review of the evidence, proposed mechanisms and implications for treatment","volume":"14","author":"Mongan","year":"2020","journal-title":"Early Interven. Psychiatr."},{"issue":"4","key":"10.1016\/j.bbih.2025.101055_bib41","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s00406-021-01237-z","article-title":"Increased peripheral inflammation in schizophrenia is associated with worse cognitive performance and related cortical thickness reductions","volume":"271","author":"North","year":"2021","journal-title":"Eur. Arch. Psychiatr. Clin. Neurosci."},{"key":"10.1016\/j.bbih.2025.101055_bib42","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.psyneuen.2015.06.009","article-title":"Cumulative stress pathophysiology in schizophrenia as indexed by allostatic load","volume":"60","author":"Nugent","year":"2015","journal-title":"Psychoneuroendocrinology"},{"issue":"9","key":"10.1016\/j.bbih.2025.101055_bib43","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1176\/appi.ajp.161.9.1603","article-title":"Middle and inferior temporal gyrus gray matter volume abnormalities in chronic schizophrenia: an MRI study","volume":"161","author":"Onitsuka","year":"2004","journal-title":"Am. J. Psychiatr."},{"issue":"9","key":"10.1016\/j.bbih.2025.101055_bib44","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1176\/ajp.2006.163.9.1630","article-title":"Increased stress-induced inflammatory responses in male patients with major depression and increased early life stress","volume":"163","author":"Pace","year":"2006","journal-title":"Am. J. Psychiatr."},{"key":"10.1016\/j.bbih.2025.101055_bib45","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.bbi.2021.07.009","article-title":"Associations of immunological proteins\/traits with schizophrenia, major depression and bipolar disorder: a Bi-directional two-sample mendelian randomization study","volume":"97","author":"Perry","year":"2021","journal-title":"Brain Behav. Immun."},{"issue":"4","key":"10.1016\/j.bbih.2025.101055_bib46","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1017\/S0033291700005092","article-title":"Perceptual changes in schizophrenia: a questionnaire survey","volume":"15","author":"Phillipson","year":"1985","journal-title":"Psychol. Med."},{"issue":"16","key":"10.1016\/j.bbih.2025.101055_bib47","doi-asserted-by":"crossref","first-page":"2736","DOI":"10.1017\/S0033291718003690","article-title":"Association between childhood trauma exposure and pro-inflammatory cytokines in schizophrenia and bipolar-I disorder","volume":"49","author":"Quid\u00e9","year":"2019","journal-title":"Psychol. Med."},{"key":"10.1016\/j.bbih.2025.101055_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2020.110013","article-title":"Systemic inflammation and grey matter volume in schizophrenia and bipolar disorder: moderation by childhood trauma severity","volume":"105","author":"Quid\u00e9","year":"2021","journal-title":"Prog. Neuro Psychopharmacol. Biol. Psychiatr."},{"issue":"5","key":"10.1016\/j.bbih.2025.101055_bib49","first-page":"2984","article-title":"Cortical thickness of functionally defined visual areas in schizophrenia and bipolar disorder","volume":"27","author":"Reavis","year":"2017","journal-title":"Cerebr. Cortex"},{"issue":"1","key":"10.1016\/j.bbih.2025.101055_bib50","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.biopsych.2010.03.036","article-title":"Cortical thickness and subcortical volumes in schizophrenia and bipolar disorder","volume":"68","author":"Rimol","year":"2010","journal-title":"Biol. Psychiatry"},{"issue":"1\u20132","key":"10.1016\/j.bbih.2025.101055_bib51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0920-9964(01)00163-3","article-title":"A review of MRI findings in schizophrenia","volume":"49","author":"Shenton","year":"2001","journal-title":"Schizophr. Res."},{"issue":"2","key":"10.1016\/j.bbih.2025.101055_bib52","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.psychres.2014.02.004","article-title":"Role of C-reactive protein in schizophrenia: an overview","volume":"216","author":"Singh","year":"2014","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.bbih.2025.101055_bib53","doi-asserted-by":"crossref","first-page":"754","DOI":"10.3389\/fimmu.2018.00754","article-title":"Role of C-reactive protein at sites of inflammation and infection","volume":"9","author":"Sproston","year":"2018","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.bbih.2025.101055_bib54","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1139\/jpn.0725","article-title":"Empirical evaluation of language disorder in schizophrenia","volume":"32","author":"Stephane","year":"2007","journal-title":"J. Psychiatry Neurosci.: JPN"},{"issue":"8","key":"10.1016\/j.bbih.2025.101055_bib55","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.3390\/molecules23082087","article-title":"Current concepts and treatments of schizophrenia","volume":"23","author":"St\u0119pnicki","year":"2018","journal-title":"Molecules : J. Synthetic Chem. Nat. Product Chem."},{"issue":"1","key":"10.1016\/j.bbih.2025.101055_bib56","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.schres.2012.10.012","article-title":"Next-generation negative symptom assessment for clinical trials: validation of the brief negative symptom scale","volume":"142","author":"Strauss","year":"2012","journal-title":"Schizophr. Res."},{"issue":"1","key":"10.1016\/j.bbih.2025.101055_bib57","doi-asserted-by":"crossref","first-page":"sgaa054","DOI":"10.1093\/schizbullopen\/sgaa054","article-title":"Semantic memory impairment across the schizophrenia continuum: a meta-analysis of category fluency performance","volume":"1","author":"Tan","year":"2020","journal-title":"Schizophrenia Bull. Open"},{"issue":"1\u20133","key":"10.1016\/j.bbih.2025.101055_bib58","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.schres.2009.03.005","article-title":"Schizophrenia, \u201cjust the facts\u201d 4. Clinical features and conceptualization","volume":"110","author":"Tandon","year":"2009","journal-title":"Schizophr. Res."},{"issue":"7","key":"10.1016\/j.bbih.2025.101055_bib59","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0040247","article-title":"Decrease in temporal gyrus gray matter volume in first-episode, early onset schizophrenia: an MRI study","volume":"7","author":"Tang","year":"2012","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.bbih.2025.101055_bib60","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.biopsych.2018.04.023","article-title":"Cortical brain abnormalities in 4474 individuals with schizophrenia and 5098 control subjects via the enhancing neuro imaging genetics through meta analysis (ENIGMA) consortium","volume":"84","author":"van Erp","year":"2018","journal-title":"Biol. Psychiatry"},{"issue":"5","key":"10.1016\/j.bbih.2025.101055_bib61","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1001\/jamapsychiatry.2022.0407","article-title":"Inflammation and brain structure in schizophrenia and other neuropsychiatric disorders: a mendelian randomization study","volume":"79","author":"Williams","year":"2022","journal-title":"JAMA Psychiatry"}],"container-title":["Brain, Behavior, & Immunity - Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666354625001139?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666354625001139?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T18:20:29Z","timestamp":1758133229000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666354625001139"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":61,"alternative-id":["S2666354625001139"],"URL":"https:\/\/doi.org\/10.1016\/j.bbih.2025.101055","relation":{},"ISSN":["2666-3546"],"issn-type":[{"value":"2666-3546","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Childhood trauma and inflammatory biomarker effects on cortical thinning in schizophrenia spectrum disorders","name":"articletitle","label":"Article Title"},{"value":"Brain, Behavior, & Immunity - Health","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbih.2025.101055","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"101055"}}