{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T01:50:43Z","timestamp":1789523443900,"version":"build-2803163510"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T00:00:00Z","timestamp":1757721600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100002220","name":"Robert E and Evelyn Mckee Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002220","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain, Behavior, & Immunity - Health"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.bbih.2025.101107","type":"journal-article","created":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T03:59:37Z","timestamp":1758081577000},"page":"101107","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Exploratory study of the dysregulation of age-related changes in neural\/glial antigen 2 and neuroinflammation markers in individuals with major depression"],"prefix":"10.1016","volume":"49","author":[{"given":"Javier","family":"Vargas-Medrano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Sotelo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guadalupe","family":"Vidal Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0089-4038","authenticated-orcid":false,"given":"Peter M.","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbih.2025.101107_bib1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.bbi.2013.10.017","article-title":"NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder","volume":"36","author":"Alcocer-G\u00f3mez","year":"2014","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbih.2025.101107_bib2","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1176\/ajp.157.4.635","article-title":"Age-related cognitive deficits mediated by changes in the striatal dopamine system","volume":"157","author":"B\u00e4ckman","year":"2000","journal-title":"Am. J. Psychiatr."},{"key":"10.1016\/j.bbih.2025.101107_bib3","doi-asserted-by":"crossref","first-page":"5151","DOI":"10.1038\/s41467-020-18984-7","article-title":"Myelination of parvalbumin interneurons shapes the function of cortical sensory inhibitory circuits","volume":"11","author":"Benamer","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbih.2025.101107_bib4","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1038\/35012083","article-title":"Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus","volume":"405","author":"Bergles","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.bbih.2025.101107_bib5","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/s41586-022-04554-y","article-title":"Brain charts for the human lifespan","volume":"604","author":"Bethlehem","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.bbih.2025.101107_bib6","doi-asserted-by":"crossref","first-page":"6946","DOI":"10.1523\/JNEUROSCI.0356-15.2015","article-title":"Age-dependent Netrin-1 signaling regulates NG2+ glial cell spatial homeostasis in normal adult gray matter","volume":"35","author":"Birey","year":"2015","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbih.2025.101107_bib7","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.neuron.2015.10.046","article-title":"Genetic and stress-induced loss of NG2 glia triggers emergence of depressive-like behaviors through reduced secretion of FGF2","volume":"88","author":"Birey","year":"2015","journal-title":"Neuron"},{"key":"10.1016\/j.bbih.2025.101107_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.mad.2021.111575","article-title":"Brain aging mechanisms with mechanical manifestations","volume":"200","author":"Blinkouskaya","year":"2021","journal-title":"Mech. Age. Dev."},{"key":"10.1016\/j.bbih.2025.101107_bib9","series-title":"International Review of Neurobiology","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0074-7742(09)00401-2","article-title":"Chapter 1 normal brain aging: clinical, immunological, neuropsychological, and neuroimaging features","author":"Caserta","year":"2009"},{"key":"10.1016\/j.bbih.2025.101107_bib10","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.jad.2021.12.111","article-title":"Reduced myelin density in unmedicated major depressive disorder: an inhomogeneous magnetization transfer MRI study","volume":"300","author":"Chen","year":"2022","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.bbih.2025.101107_bib11","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/0006-3223(95)00295-2","article-title":"Lifetime rates of suicide attempts among subjects with bipolar and unipolar disorders relative to subjects with other Axis I disorders","volume":"39","author":"Chen","year":"1996","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbih.2025.101107_bib12","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/wps.20128","article-title":"Risks of all-cause and suicide mortality in mental disorders: a meta-review","volume":"13","author":"Chesney","year":"2014","journal-title":"World Psychiatry"},{"key":"10.1016\/j.bbih.2025.101107_bib13","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1093\/cercor\/12.7.767","article-title":"Degenerative Age changes in white matter connectivity visualized in vivo using magnetic resonance imaging","volume":"12","author":"Davatzikos","year":"2002","journal-title":"Cerebr. Cortex"},{"key":"10.1016\/j.bbih.2025.101107_bib14","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/S1044-7431(03)00210-0","article-title":"NG2-expressing glial progenitor cells: an abundant and widespread population of cycling cells in the adult rat CNS","volume":"24","author":"Dawson","year":"2003","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.bbih.2025.101107_bib15","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.jad.2009.04.027","article-title":"Regionally-specific changes in levels of tumour necrosis factor in the dorsolateral prefrontal cortex obtained postmortem from subjects with major depressive disorder","volume":"120","author":"Dean","year":"2010","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.bbih.2025.101107_bib16","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.biopsych.2009.09.033","article-title":"A meta-analysis of cytokines in major depression","volume":"67","author":"Dowlati","year":"2010","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbih.2025.101107_bib17","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aam7816","article-title":"BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions","volume":"9","author":"Fard","year":"2017","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.bbih.2025.101107_bib18","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.neuron.2024.10.019","article-title":"White matter aging and its impact on brain function","volume":"113","author":"Groh","year":"2025","journal-title":"Neuron"},{"key":"10.1016\/j.bbih.2025.101107_bib19","doi-asserted-by":"crossref","first-page":"5124","DOI":"10.1038\/s41380-020-0754-0","article-title":"Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group","volume":"26","author":"Han","year":"2021","journal-title":"Mol. Psychiatr."},{"key":"10.1016\/j.bbih.2025.101107_bib20","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.colsurfb.2007.09.009","article-title":"HGF protects cultured cortical neurons against hypoxia\/reoxygenation induced cell injury via ERK1\/2 and PI-3K\/Akt pathways","volume":"61","author":"He","year":"2008","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.bbih.2025.101107_bib21","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1038\/s41593-018-0120-6","article-title":"Lifelong cortical myelin plasticity and age-related degeneration in the live mammalian brain","volume":"21","author":"Hill","year":"2018","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbih.2025.101107_bib22","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.chembiol.2016.06.006","article-title":"Structural basis for KDM5A histone lysine demethylase inhibition by diverse compounds","volume":"23","author":"Horton","year":"2016","journal-title":"Cell Chem. Biol."},{"key":"10.1016\/j.bbih.2025.101107_bib23","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1038\/nn.3390","article-title":"Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain","volume":"16","author":"Hughes","year":"2013","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbih.2025.101107_bib24","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1038\/s41593-018-0121-5","article-title":"Myelin remodeling through experience-dependent oligodendrogenesis in the adult somatosensory cortex","volume":"21","author":"Hughes","year":"2018","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbih.2025.101107_bib25","first-page":"462","article-title":"Accelerated brain aging in adults with major depressive disorder predicts poorer outcome with sertraline: findings from the EMBARC Study","volume":"8","author":"Jha","year":"2023","journal-title":"Biol. Psychiatry Cogn. Neurosci. Neuroimaging"},{"key":"10.1016\/j.bbih.2025.101107_bib26","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.neuron.2010.09.009","article-title":"NG2+ CNS glial progenitors remain committed to the oligodendrocyte lineage in postnatal life and following neurodegeneration","volume":"68","author":"Kang","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.bbih.2025.101107_bib27","doi-asserted-by":"crossref","first-page":"2659","DOI":"10.1038\/s41380-022-01511-z","article-title":"The blood-brain barrier in aging and neurodegeneration","volume":"27","author":"Knox","year":"2022","journal-title":"Mol. Psychiatr."},{"key":"10.1016\/j.bbih.2025.101107_bib28","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.bbih.2025.101107_bib29","doi-asserted-by":"crossref","first-page":"4716","DOI":"10.1523\/JNEUROSCI.14-08-04716.1994","article-title":"Increased expression of the NG2 chondroitin-sulfate proteoglycan after brain injury","volume":"14","author":"Levine","year":"1994","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbih.2025.101107_bib30","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/nn1162","article-title":"Synaptic signaling between GABAergic interneurons and oligodendrocyte precursor cells in the hippocampus","volume":"7","author":"Lin","year":"2004","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbih.2025.101107_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2022.105926","article-title":"Blood brain barrier and inflammation in depression","volume":"175","author":"Medina-Rodriguez","year":"2022","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.bbih.2025.101107_bib32","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1097\/00004647-199804000-00001","article-title":"Protection of hippocampal neurons from ischemia-induced delayed neuronal death by hepatocyte growth factor: a novel neurotrophic factor","volume":"18","author":"Miyazawa","year":"1998","journal-title":"J. Cerebr. Blood Flow Metabol."},{"key":"10.1016\/j.bbih.2025.101107_bib33","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/j.1365-2990.2008.01003a.x","article-title":"pH measurement as quality control on human post mortem brain tissue: a study of the BrainNet Europe consortium","volume":"35","author":"Monoranu","year":"2009","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"10.1016\/j.bbih.2025.101107_bib34","first-page":"12","article-title":"The neuropsychology of memory and aging","volume":"315","author":"Moscovitch","year":"1992","journal-title":"Handbook Aging Cogn."},{"key":"10.1016\/j.bbih.2025.101107_bib35","doi-asserted-by":"crossref","first-page":"4094","DOI":"10.1523\/JNEUROSCI.4825-12.2013","article-title":"Altered synaptic dynamics during normal brain aging","volume":"33","author":"Mostany","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbih.2025.101107_bib36","doi-asserted-by":"crossref","DOI":"10.1038\/srep42041","article-title":"NG2 glial cells regulate neuroimmunological responses to maintain neuronal function and survival","volume":"7","author":"Nakano","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbih.2025.101107_bib37","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/nrn2797","article-title":"Myelination and the trophic support of long axons","volume":"11","author":"Nave","year":"2010","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.bbih.2025.101107_bib38","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.ejphar.2006.01.037","article-title":"Effects of hepatocyte growth factor on phosphorylation of extracellular signal-regulated kinase and hippocampal cell death in rats with transient forebrain ischemia","volume":"535","author":"Niimura","year":"2006","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bbih.2025.101107_bib39","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/nrn2495","article-title":"Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity","volume":"10","author":"Nishiyama","year":"2009","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.bbih.2025.101107_bib40","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1146\/annurev.psych.59.103006.093656","article-title":"The adaptive brain: aging and neurocognitive scaffolding","volume":"60","author":"Park","year":"2009","journal-title":"Annu. Rev. Psychol."},{"key":"10.1016\/j.bbih.2025.101107_bib41","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1017\/S1740925X09990354","article-title":"Cell cycle dynamics of NG2 cells in the postnatal and ageing brain","volume":"5","author":"Psachoulia","year":"2009","journal-title":"Neuron Glia Biol."},{"key":"10.1016\/j.bbih.2025.101107_bib42","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jpsychires.2015.04.010","article-title":"Oligodendrocyte morphometry and expression of myelin - related mRNA in ventral prefrontal white matter in major depressive disorder","volume":"65","author":"Rajkowska","year":"2015","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.bbih.2025.101107_bib43","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1038\/nn.2220","article-title":"PDGFRA\/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice","volume":"11","author":"Rivers","year":"2008","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbih.2025.101107_bib44","doi-asserted-by":"crossref","first-page":"2200","DOI":"10.1038\/s41598-017-02062-y","article-title":"Myelination of the brain in major depressive disorder: an in vivo quantitative magnetic resonance imaging study","volume":"7","author":"Sacchet","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbih.2025.101107_bib45","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0127222","article-title":"Oligodendrocyte precursor cells synthesize neuromodulatory factors","volume":"10","author":"Sakry","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.bbih.2025.101107_bib46","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1093\/cercor\/bhh032","article-title":"Thinning of the cerebral cortex in aging","volume":"14","author":"Salat","year":"2004","journal-title":"Cerebr. Cortex"},{"key":"10.1016\/j.bbih.2025.101107_bib47","doi-asserted-by":"crossref","DOI":"10.1042\/NS20210008","article-title":"Oligodendrocytes in the aging brain","volume":"5","author":"Sams","year":"2021","journal-title":"Neuronal Signal."},{"key":"10.1016\/j.bbih.2025.101107_bib48","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1016\/S0140-6736(21)02143-7","article-title":"Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic","volume":"398","author":"Santomauro","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.bbih.2025.101107_bib49","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1007\/s00429-022-02503-z","article-title":"Aging and white matter microstructure and macrostructure: a longitudinal multi-site diffusion MRI study of 1218 participants","volume":"227","author":"Schilling","year":"2022","journal-title":"Brain Struct. Funct."},{"issue":"Suppl. 20","key":"10.1016\/j.bbih.2025.101107_bib50","first-page":"22","article-title":"The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10","volume":"59","author":"Sheehan","year":"1998","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.bbih.2025.101107_bib51","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1161\/01.CIR.0000109496.82683.49","article-title":"Novel therapeutic strategy to treat brain ischemia: overexpression of hepatocyte growth factor gene reduced ischemic injury without cerebral edema in rat model","volume":"109","author":"Shimamura","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.bbih.2025.101107_bib52","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/0003-2697(85)90442-7","article-title":"Measurement of protein using bicinchoninic acid","volume":"150","author":"Smith","year":"1985","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bbih.2025.101107_bib53","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2006.09.025","article-title":"Human postmortem tissue: what quality markers matter?","volume":"1123","author":"Stan","year":"2006","journal-title":"Brain Res."},{"key":"10.1016\/j.bbih.2025.101107_bib54","doi-asserted-by":"crossref","first-page":"4350","DOI":"10.1073\/pnas.76.9.4350","article-title":"Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications","volume":"76","author":"Towbin","year":"1979","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.bbih.2025.101107_bib55","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1179\/016164101101198659","article-title":"Hepatocyte growth factor reduces the infarct volume after transient focal cerebral ischemia in rats","volume":"23","author":"Tsuzuki","year":"2001","journal-title":"Neurol. Res."},{"key":"10.1016\/j.bbih.2025.101107_bib56","series-title":"Proceedings of the 11th International Symposium, Newcastle-upon-Tyne, United Kingdom, June 6\u201310, 1999","first-page":"311","article-title":"Hepatocyte growth factor reduces infarct volume after transient focal cerebral ischemia in rats. Brain Edema XI","author":"Tsuzuki","year":"2000"},{"key":"10.1016\/j.bbih.2025.101107_bib57","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1590\/1806-9282.65.3.361","article-title":"Increased levels of plasma IL-1b and BDNF can predict resistant depression patients","volume":"65","author":"Uint","year":"2019","journal-title":"Rev. Assoc. M\u00e9d. Bras."},{"key":"10.1016\/j.bbih.2025.101107_bib58","doi-asserted-by":"crossref","DOI":"10.1155\/2011\/174689","article-title":"Age-related increase in the number of oligodendrocytes is dysregulated in schizophrenia and mood disorders","volume":"2011","author":"Vostrikov","year":"2011","journal-title":"Schizophr Res Treatment"},{"key":"10.1016\/j.bbih.2025.101107_bib59","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0109387","article-title":"Pro-inflammatory cytokines reduce the proliferation of NG2 cells and increase shedding of NG2 in vivo and in vitro","volume":"9","author":"Wennstr\u00f6m","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.bbih.2025.101107_bib60","series-title":"Preventing Suicide: a Resource for Media Professionals, 2023 Update","year":"2023"},{"key":"10.1016\/j.bbih.2025.101107_bib61","doi-asserted-by":"crossref","first-page":"4967","DOI":"10.1523\/JNEUROSCI.23-12-04967.2003","article-title":"Oligodendrocytes promote neuronal survival and axonal length by distinct intracellular mechanisms: a novel role for oligodendrocyte-derived glial cell line-derived neurotrophic factor","volume":"23","author":"Wilkins","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbih.2025.101107_bib62","article-title":"The DNA methylome and transcriptome of different brain regions in schizophrenia and bipolar disorder","volume":"9","author":"Xiao","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.bbih.2025.101107_bib63","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/S0002-9440(10)64058-8","article-title":"Hepatocyte growth factor enhances vascular endothelial growth factor-induced angiogenesis in vitro and in vivo","volume":"158","author":"Xin","year":"2001","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.bbih.2025.101107_bib64","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.neuron.2013.01.006","article-title":"Oligodendrocyte dynamics in the healthy adult CNS: evidence for myelin remodeling","volume":"77","author":"Young","year":"2013","journal-title":"Neuron"},{"key":"10.1016\/j.bbih.2025.101107_bib65","series-title":"NG2 Cells Generate both Oligodendrocytes and Gray Matter Astrocytes","author":"Zhu","year":"2008"},{"key":"10.1016\/j.bbih.2025.101107_bib66","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1017\/S1740925X09000015","article-title":"NG2 cells generate oligodendrocytes and gray matter astrocytes in the spinal cord","volume":"4","author":"Zhu","year":"2008","journal-title":"Neuron Glia Biol."},{"key":"10.1016\/j.bbih.2025.101107_bib67","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1038\/nn1854","article-title":"Vesicular release of glutamate from unmyelinated axons in white matter","volume":"10","author":"Ziskin","year":"2007","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbih.2025.101107_bib68","doi-asserted-by":"crossref","DOI":"10.3390\/diagnostics10121014","article-title":"Postmortem protein degradation as a tool to estimate the PMI: a systematic review","volume":"10","author":"Zissler","year":"2020","journal-title":"Diagnostics"}],"container-title":["Brain, Behavior, & Immunity - Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666354625001656?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666354625001656?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T21:21:20Z","timestamp":1772918480000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666354625001656"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":68,"alternative-id":["S2666354625001656"],"URL":"https:\/\/doi.org\/10.1016\/j.bbih.2025.101107","relation":{},"ISSN":["2666-3546"],"issn-type":[{"value":"2666-3546","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exploratory study of the dysregulation of age-related changes in neural\/glial antigen 2 and neuroinflammation markers in individuals with major depression","name":"articletitle","label":"Article Title"},{"value":"Brain, Behavior, & Immunity - Health","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbih.2025.101107","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"101107"}}