{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:09:44Z","timestamp":1761487784782,"version":"build-2065373602"},"reference-count":27,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2015,4,10]],"date-time":"2015-04-10T00:00:00Z","timestamp":1428624000000},"content-version":"vor","delay-in-days":2901,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["bbmt.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biology of Blood and Marrow Transplantation"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1016\/j.bbmt.2006.12.449","type":"journal-article","created":{"date-parts":[[2007,2,23]],"date-time":"2007-02-23T11:36:58Z","timestamp":1172230618000},"page":"560-567","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["A Prospective Multicenter Trial of Peripheral Blood Stem Cell Sibling Allografts for Acute Myeloid Leukemia in First Complete Remission Using Fludarabine-Cyclophosphamide Reduced Intensity Conditioning"],"prefix":"10.1016","volume":"13","author":[{"given":"A.P.","family":"Grigg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Gibson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.G.","family":"Bardy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Reynolds","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Shuttleworth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.L.","family":"Koelmeyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Szer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.W.","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.B.","family":"To","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Kennedy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.F.","family":"Bradstock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbmt.2006.12.449_bib1","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1046\/j.1365-2141.2002.03698.x","article-title":"Current controversies: which patients with acute myeloid leukaemia should receive a bone marrow transplantation?","volume":"118","author":"Burnett","year":"2002","journal-title":"Br J Haematol."},{"key":"10.1016\/j.bbmt.2006.12.449_bib2","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1046\/j.1365-2141.2002.03696.x","article-title":"Current controversies: which patients with acute myeloid leukaemia should receive a bone marrow transplantation?","volume":"118","author":"Wheatley","year":"2002","journal-title":"Br J Haematol."},{"key":"10.1016\/j.bbmt.2006.12.449_bib3","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.1200\/JCO.1998.16.8.2817","article-title":"Transplant-lite: induction of graft-versus-malignancy using fludarabine-based nonablative chemotherapy and allogeneic blood progenitor-cell transplantation as treatment for lymphoid malignancies","volume":"16","author":"Khouri","year":"1998","journal-title":"J Clin Oncol."},{"key":"10.1016\/j.bbmt.2006.12.449_bib4","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1182\/blood.V97.3.631","article-title":"Melphalan and purine analog-containing preparative regimens: reduced-intensity conditioning for patients with hematologic malignancies undergoing allogeneic progenitor cell transplantation","volume":"97","author":"Giralt","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2006.12.449_bib5","doi-asserted-by":"crossref","first-page":"4075","DOI":"10.1182\/blood.V96.13.4075","article-title":"Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group\/Eastern Cooperative Oncology Group study","volume":"96","author":"Slovak","year":"2000","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2006.12.449_bib6","doi-asserted-by":"crossref","first-page":"2322","DOI":"10.1182\/blood.V92.7.2322","article-title":"The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial","volume":"92","author":"Grimwade","year":"1998","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2006.12.449_bib7","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1046\/j.1365-2141.2002.03724.x","article-title":"The value of allogeneic bone marrow transplant in patients with acute myeloid leukaemia at differing risk of relapse: results of the UK MRC AML 10 trial","volume":"118","author":"Burnett","year":"2002","journal-title":"Br J Haematol."},{"key":"10.1016\/j.bbmt.2006.12.449_bib8","doi-asserted-by":"crossref","first-page":"3234","DOI":"10.1182\/blood.V94.9.3234","article-title":"Engraftment kinetics after nonmyeloablative allogeneic peripheral blood stem cell transplantation: full donor T-cell chimerism precedes alloimmune responses","volume":"94","author":"Childs","year":"1999","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2006.12.449_bib9","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S1083-8791(03)00128-9","article-title":"Graft-versus-host disease, donor chimerism, and organ toxicity in stem cell transplantation after conditioning with fludarabine and melphalan","volume":"9","author":"Ritchie","year":"2003","journal-title":"Biol Blood Marrow Transplant."},{"key":"10.1016\/j.bbmt.2006.12.449_bib10","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1200\/JCO.1989.7.9.1288","article-title":"Regimen-related toxicity and early posttransplant survival in patients undergoing marrow transplantation for lymphoma","volume":"7","author":"Bearman","year":"1989","journal-title":"J Clin Oncol."},{"key":"10.1016\/j.bbmt.2006.12.449_bib11","doi-asserted-by":"crossref","first-page":"3569","DOI":"10.1182\/blood.V98.13.3569","article-title":"Busulfan plus cyclophosphamide compared with total-body irradiation plus cyclophosphamide before marrow transplantation for myeloid leukemia: long-term follow-up of 4 randomized studies","volume":"98","author":"Soci\u00e9","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2006.12.449_bib12","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1038\/sj.leu.2404328","article-title":"Reduced-intensity conditioning for acute myeloid leukemia: is this strategy correct","volume":"20","author":"Lazarus","year":"2006","journal-title":"Leukemia"},{"key":"10.1016\/j.bbmt.2006.12.449_bib13","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1002\/cncr.21418","article-title":"Reduced intensity conditioning prior to allogeneic stem cell transplantation for patients with acute myeloblastic leukemia as a first-line treatment","volume":"104","author":"Blaise","year":"2005","journal-title":"Cancer"},{"key":"10.1016\/j.bbmt.2006.12.449_bib14","doi-asserted-by":"crossref","first-page":"3959","DOI":"10.1200\/JCO.2006.05.5855","volume":"24","author":"Gorin","year":"2006","journal-title":"J Clin Oncol."},{"key":"10.1016\/j.bbmt.2006.12.449_bib15","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1182\/blood-2003-11-3750","article-title":"Nonablative versus reduced-intensity conditioning regimens in the treatment of acute myeloid leukemia and high-risk myelodysplastic syndrome: dose is relevant for long-term disease control after allogeneic hematopoietic stem cell transplantation","volume":"104","author":"de-Lima","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2006.12.449_bib16","doi-asserted-by":"crossref","first-page":"18a","DOI":"10.1182\/blood.V106.11.47.47","article-title":"Allogeneic hematopoietic stem-cell transplantation in AML and MDS using myeloablative versus reduced intensity conditioning: the role of dose-intensity","volume":"106","author":"Shimoni","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2006.12.449_bib17","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1111\/j.1365-2141.2005.05614.x","article-title":"Influence of the intensity of the conditioning regimen on the characteristics of acute and chronic graft-versus-host disease after allogeneic transplantation","volume":"130","author":"Perez-Simon","year":"2005","journal-title":"Br J Haematol."},{"key":"10.1016\/j.bbmt.2006.12.449_bib18","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1182\/blood-2002-02-0400","article-title":"Evidence for a graft-versus-leukemia effect after allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning in acute myelogenous leukemia and myelodysplastic syndromes","volume":"100","author":"Martino","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2006.12.449_bib19","doi-asserted-by":"crossref","first-page":"2304","DOI":"10.1038\/sj.leu.2403967","volume":"19","author":"Aoudjhane","year":"2005","journal-title":"Leukemia"},{"key":"10.1016\/j.bbmt.2006.12.449_bib20","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1182\/blood-2002-11-3567","article-title":"Conditioning with fludarabine and targeted busulfan for transplantation of allogeneic hematopoietic stem cells","volume":"102","author":"Bornhauser","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2006.12.449_bib21","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1038\/sj.bmt.1703230","article-title":"The gut mucosa barrier is preserved during allogeneic, haemopoietic stem cell transplantation with reduced intensity conditioning","volume":"28","author":"Johansson","year":"2001","journal-title":"Bone Marrow Transplant."},{"key":"10.1016\/j.bbmt.2006.12.449_bib22","doi-asserted-by":"crossref","first-page":"9387","DOI":"10.1200\/JCO.2005.02.0057","article-title":"Allogeneic stem-cell transplantation using a reduced-intensity conditioning regimen has the capacity to produce durable remissions and long-term disease-free survival in patients with high-risk acute myeloid leukemia and myelodysplasia","volume":"23","author":"Tauro","year":"2005","journal-title":"J Clin Oncol."},{"key":"10.1016\/j.bbmt.2006.12.449_bib23","doi-asserted-by":"crossref","first-page":"5728","DOI":"10.1200\/JCO.2005.15.602","article-title":"Fludarabine, melphalan, and alemtuzumab conditioning in adults with standard-risk advanced acute myeloid leukemia and myelodysplastic syndrome","volume":"23","author":"Van Besien","year":"2005","journal-title":"J Clin Oncol."},{"key":"10.1016\/j.bbmt.2006.12.449_bib24","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1111\/j.1365-2141.2005.05533.x","article-title":"Outcomes of patients with acute leukaemia who relapsed after reduced-intensity stem cell transplantation from HLA-identical or one antigen-mismatched related donors","volume":"129","author":"Kobayashi","year":"2005","journal-title":"Br J Haematol."},{"key":"10.1016\/j.bbmt.2006.12.449_bib25","doi-asserted-by":"crossref","first-page":"3314","DOI":"10.1182\/blood-2005-04-1377","article-title":"Conditioning with 8-Gy total body irradiation and fludarabine for allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia","volume":"106","author":"Stelljes","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2006.12.449_bib26","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1182\/blood-2002-08-2628","article-title":"Graft-versus-host disease after nonmyeloablative versus conventional hematopoietic stem cell transplantation","volume":"102","author":"Mielcarek","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2006.12.449_bib27","doi-asserted-by":"crossref","first-page":"6a","DOI":"10.1182\/blood.V108.11.4.4","article-title":"Gene mutations as predictive markers for pertremission therapy in younger adults with normal karyotype AML","volume":"108","author":"Schlenk","year":"2006","journal-title":"Blood"}],"container-title":["Biology of Blood and Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083879106013140?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083879106013140?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T14:29:17Z","timestamp":1761056957000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1083879106013140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["S1083879106013140"],"URL":"https:\/\/doi.org\/10.1016\/j.bbmt.2006.12.449","relation":{},"ISSN":["1083-8791"],"issn-type":[{"type":"print","value":"1083-8791"}],"subject":[],"published":{"date-parts":[[2007,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Prospective Multicenter Trial of Peripheral Blood Stem Cell Sibling Allografts for Acute Myeloid Leukemia in First Complete Remission Using Fludarabine-Cyclophosphamide Reduced Intensity Conditioning","name":"articletitle","label":"Article Title"},{"value":"Biology of Blood and Marrow Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbmt.2006.12.449","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}