{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T12:59:31Z","timestamp":1791291571526,"version":"4.3.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2015,4,10]],"date-time":"2015-04-10T00:00:00Z","timestamp":1428624000000},"content-version":"vor","delay-in-days":2565,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bbmt.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biology of Blood and Marrow Transplantation"],"published-print":{"date-parts":[[2008,4]]},"DOI":"10.1016\/j.bbmt.2008.02.001","type":"journal-article","created":{"date-parts":[[2008,3,14]],"date-time":"2008-03-14T10:05:35Z","timestamp":1205489135000},"page":"426-437","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Circulating Endothelial Progenitor Cells Decreased in Patients with Sclerodermatous Chronic Graft-versus-Host Disease"],"prefix":"10.1016","volume":"14","author":[{"given":"Kazuho","family":"Shimura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eishi","family":"Ashihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chihiro","family":"Shimazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinsaku","family":"Matsunaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoko","family":"Taniguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoji","family":"Uchiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yosuke","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Kimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Matsubara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masafumi","family":"Taniwaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taira","family":"Maekawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbmt.2008.02.001_bib1","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/sj.bmt.1704410","article-title":"Chronic graft-versus-host disease: where do we go from here?","volume":"33","author":"Farag","year":"2004","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2008.02.001_bib2","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1016\/S0140-6736(02)08907-9","article-title":"Endothelial injury mediated by cytotoxic T lymphocytes and loss of microvessels in chronic graft versus host disease","volume":"359","author":"Biedermann","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.bbmt.2008.02.001_bib3","doi-asserted-by":"crossref","first-page":"2993","DOI":"10.1182\/blood-2005-09-3623","article-title":"Donor CD4+ T and B cells in transplants induce chronic graft-versus-host disease with autoimmune manifestations","volume":"107","author":"Zhang","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2008.02.001_bib4","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/S0889-857X(05)70295-7","article-title":"Systemic sclerosis. A vascular perspective","volume":"22","author":"LeRoy","year":"1996","journal-title":"Rheum Dis Clin North Am"},{"key":"10.1016\/j.bbmt.2008.02.001_bib5","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S0140-6736(04)16853-0","article-title":"Defective vasculogenesis in systemic sclerosis","volume":"364","author":"Kuwana","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.bbmt.2008.02.001_bib6","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1097\/00007890-197410000-00001","article-title":"Clinical manifestations of\u00a0graft-versus-host disease in human recipients of marrow from HL-A-matched sibling donors","volume":"18","author":"Glucksberg","year":"1974","journal-title":"Transplantation"},{"key":"10.1016\/j.bbmt.2008.02.001_bib7","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/0002-9343(80)90380-0","article-title":"Chronic graft-versus-host syndrome in man. A long-term clinicopathologic study of 20 Seattle patients","volume":"69","author":"Shulman","year":"1980","journal-title":"Am J Med"},{"key":"10.1016\/j.bbmt.2008.02.001_bib8","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1053\/bbmt.2003.50026","article-title":"Chronic graft-versus-host disease","volume":"9","author":"Lee","year":"2003","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2008.02.001_bib9","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/j.bbmt.2005.09.004","article-title":"National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. Diagnosis and staging working group report","volume":"11","author":"Filipovich","year":"2005","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2008.02.001_bib10","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1089\/scd.1.1996.5.213","article-title":"The ISHAGE guidelines for CD34+ cell determination by flow cytometry. International Society of Hematotherapy and Graft Engineering","volume":"5","author":"Sutherland","year":"1996","journal-title":"J Hematother"},{"key":"10.1016\/j.bbmt.2008.02.001_bib11","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1038\/nm0603-702","article-title":"Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration","volume":"9","author":"Rafii","year":"2003","journal-title":"Nat Med"},{"key":"10.1016\/j.bbmt.2008.02.001_bib12","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1182\/blood-2004-05-1831","article-title":"Increased circulating hematopoietic and endothelial progenitor cells in the early phase of acute myocardial infarction","volume":"105","author":"Massa","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2008.02.001_bib13","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1038\/7434","article-title":"Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization","volume":"5","author":"Takahashi","year":"1999","journal-title":"Nat Med"},{"key":"10.1016\/j.bbmt.2008.02.001_bib14","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/sj.leu.2404018","article-title":"Engraftment capacity of mesenchymal cells following hematopoietic stem cell transplantation in patients receiving reduced-intensity conditioning regimen","volume":"20","author":"Poloni","year":"2006","journal-title":"Leukemia"},{"key":"10.1016\/j.bbmt.2008.02.001_bib15","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1136\/ard.62.9.904","article-title":"European Scleroderma Study Group to define disease activity criteria for systemic sclerosis. IV. Assessment of skin thickening by modified Rodnan skin score","volume":"62","author":"Valentini","year":"2003","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.bbmt.2008.02.001_bib16","first-page":"258","article-title":"Sclerodermatous chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation: incidence, predictors and outcome","volume":"91","author":"Skert","year":"2006","journal-title":"Haematologica"},{"key":"10.1016\/j.bbmt.2008.02.001_bib17","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/j.exphem.2005.04.009","article-title":"Posttransplant hematopoiesis in patients undergoing sibling allogeneic stem cell transplantation reflects that of their respective donors although with a lower functional capability","volume":"33","author":"Sanchez-Guijo","year":"2005","journal-title":"Exp Hematol"},{"key":"10.1016\/j.bbmt.2008.02.001_bib18","doi-asserted-by":"crossref","first-page":"3603","DOI":"10.1182\/blood-2003-10-3479","article-title":"Circulating endothelial cells as a marker of endothelial damage in allogeneic hematopoietic stem cell transplantation","volume":"103","author":"Woywodt","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2008.02.001_bib19","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1126\/science.275.5302.964","article-title":"Isolation of putative progenitor endothelial cells for angiogenesis","volume":"275","author":"Asahara","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.bbmt.2008.02.001_bib20","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.1161\/hh1301.093953","article-title":"Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease","volume":"89","author":"Vasa","year":"2001","journal-title":"Circ Res"},{"key":"10.1016\/j.bbmt.2008.02.001_bib21","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1056\/NEJMoa022287","article-title":"Circulating endothelial progenitor cells, vascular function, and cardiovascular risk","volume":"348","author":"Hill","year":"2003","journal-title":"N Engl J Med"},{"issue":"1 Suppl","key":"10.1016\/j.bbmt.2008.02.001_bib22","first-page":"I114","article-title":"The impact of the capability of circulating progenitor cell to differentiate on myocardial salvage in patients with primary acute myocardial infarction","volume":"114","author":"Numaguchi","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.bbmt.2008.02.001_bib23","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/S0008-6363(02)00785-X","article-title":"Post-natal endothelial progenitor cells for neovascularization in tissue regeneration","volume":"58","author":"Masuda","year":"2003","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.bbmt.2008.02.001_bib24","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S0140-6736(02)09670-8","article-title":"Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial","volume":"360","author":"Tateishi-Yuyama","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.bbmt.2008.02.001_bib25","doi-asserted-by":"crossref","first-page":"2605","DOI":"10.1002\/art.22035","article-title":"Bone marrow endothelial progenitors are defective in systemic sclerosis","volume":"54","author":"Del Papa","year":"2006","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.bbmt.2008.02.001_bib26","doi-asserted-by":"crossref","first-page":"2781","DOI":"10.1161\/01.CIR.0000039526.42991.93","article-title":"Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures","volume":"106","author":"Tepper","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.bbmt.2008.02.001_bib27","first-page":"5875","article-title":"Endothelial progenitor cells as putative targets for angiostatin","volume":"59","author":"Ito","year":"1999","journal-title":"Cancer Res"},{"key":"10.1016\/j.bbmt.2008.02.001_bib28","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1182\/blood-2006-08-043471","article-title":"Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem\/progenitor cell principals","volume":"109","author":"Yoder","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2008.02.001_bib29","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1038\/sj.leu.2403996","article-title":"Rituximab is effective for steroid-refractory sclerodermatous chronic graft-versus-host disease","volume":"20","author":"Okamoto","year":"2006","journal-title":"Leukemia"},{"key":"10.1016\/j.bbmt.2008.02.001_bib30","doi-asserted-by":"crossref","first-page":"3074","DOI":"10.1182\/blood-2005-09-3907","article-title":"Extracorporeal photochemotherapy for the treatment of steroid-resistant chronic GVHD","volume":"107","author":"Couriel","year":"2006","journal-title":"Blood"}],"container-title":["Biology of Blood and Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083879108000670?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083879108000670?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T14:30:58Z","timestamp":1761057058000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1083879108000670"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["S1083879108000670"],"URL":"https:\/\/doi.org\/10.1016\/j.bbmt.2008.02.001","relation":{},"ISSN":["1083-8791"],"issn-type":[{"value":"1083-8791","type":"print"}],"subject":[],"published":{"date-parts":[[2008,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Circulating Endothelial Progenitor Cells Decreased in Patients with Sclerodermatous Chronic Graft-versus-Host Disease","name":"articletitle","label":"Article Title"},{"value":"Biology of Blood and Marrow Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbmt.2008.02.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}