{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T09:58:00Z","timestamp":1768816680134,"version":"3.49.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2015,4,10]],"date-time":"2015-04-10T00:00:00Z","timestamp":1428624000000},"content-version":"vor","delay-in-days":1287,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["bbmt.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biology of Blood and Marrow Transplantation"],"published-print":{"date-parts":[[2011,10]]},"DOI":"10.1016\/j.bbmt.2011.02.012","type":"journal-article","created":{"date-parts":[[2011,3,8]],"date-time":"2011-03-08T02:00:47Z","timestamp":1299549647000},"page":"1512-1519","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":85,"title":["Blood, and Not Urine, BK Viral Load Predicts Renal Outcome in Children with Hemorrhagic Cystitis following Hematopoietic Stem Cell Transplantation"],"prefix":"10.1016","volume":"17","author":[{"given":"Hilary L.","family":"Haines","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin L.","family":"Laskin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Goebel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stella M.","family":"Davies","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong J.","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Lawrence","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parinda A.","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack J.","family":"Bleesing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra H.","family":"Filipovich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca A.","family":"Marsh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonata","family":"Jodele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbmt.2011.02.012_bib1","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1097\/TP.0b013e318197c17d","article-title":"The decade of polyomavirus BK-associated nephropathy: state of affairs","volume":"87","author":"Ramos","year":"2009","journal-title":"Transplantation"},{"key":"10.1016\/j.bbmt.2011.02.012_bib2","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S1473-3099(03)00770-9","article-title":"Polyomavirus BK","volume":"3","author":"Hirsch","year":"2003","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.bbmt.2011.02.012_bib3","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1056\/NEJM198607243150405","article-title":"Association of BK viruria with hemorrhagic cystitis in recipients of bone marrow transplants","volume":"315","author":"Arthur","year":"1986","journal-title":"N Engl J Med"},{"key":"10.1016\/j.bbmt.2011.02.012_bib4","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1080\/08880010252899424","article-title":"BK virus-associated fatal renal failure following late-onset hemorrhagic cystitis in an unrelated bone marrow transplantation","volume":"19","author":"Iwamoto","year":"2002","journal-title":"Pediatr Hematol Oncol"},{"key":"10.1016\/j.bbmt.2011.02.012_bib5","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/ajh.21358","article-title":"BK virus nephropathy after allogeneic stem cell transplantation: a case report and literature review","volume":"84","author":"Lekakis","year":"2009","journal-title":"Am J Hematol"},{"key":"10.1016\/j.bbmt.2011.02.012_bib6","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1111\/j.1399-3046.2008.01069.x","article-title":"BK nephropathy in pediatric hematopoietic stem cell transplant recipients","volume":"13","author":"Verghese","year":"2009","journal-title":"Pediatr Transplant"},{"key":"10.1016\/j.bbmt.2011.02.012_bib7","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1002\/pbc.22860","article-title":"BK virus nephropathy in a pediatric autologous stem-cell transplant recipient","volume":"56","author":"Sanchez-Pinto","year":"2011","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.bbmt.2011.02.012_bib8","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1128\/jcm.27.6.1174-1179.1989","article-title":"Detection of BK virus and JC virus in urine and brain tissue by the polymerase chain reaction","volume":"27","author":"Arthur","year":"1989","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.bbmt.2011.02.012_bib9","doi-asserted-by":"crossref","first-page":"411","DOI":"10.3109\/13550289609146907","article-title":"Human polyomaviruses DNA detection in peripheral blood leukocytes from immunocompetent and immunocompromised individuals","volume":"2","author":"Azzi","year":"1996","journal-title":"J Neurovirol"},{"key":"10.1016\/j.bbmt.2011.02.012_bib10","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1200\/JCO.1995.13.5.1103","article-title":"Association of BK virus with failure of prophylaxis against hemorrhagic cystitis following bone marrow transplantation","volume":"13","author":"Bedi","year":"1995","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.bbmt.2011.02.012_bib11","first-page":"401","article-title":"The incidence of hemorrhagic cystitis and BK-viruria in allogeneic hematopoietic stem cell recipients according to intensity of the conditioning regimen","volume":"91","author":"Giraud","year":"2006","journal-title":"Haematologica"},{"key":"10.1016\/j.bbmt.2011.02.012_bib12","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1056\/NEJMoa020439","article-title":"Prospective study of polyomavirus type BK replication and nephropathy in renal-transplant recipients","volume":"347","author":"Hirsch","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.bbmt.2011.02.012_bib13","doi-asserted-by":"crossref","unstructured":"Laskin BL, Goebel J. Cost-efficient screening for BK virus in pediatric kidney transplantation: a single-center experience and review of the literature. Pediatr Transplant. 14:589-595.","DOI":"10.1111\/j.1399-3046.2010.01318.x"},{"issue":"Suppl 3","key":"10.1016\/j.bbmt.2011.02.012_bib14","first-page":"S1","article-title":"KDIGO clinical practice guideline for the care of kidney transplant recipients","volume":"9","year":"2009","journal-title":"Am J Transplant"},{"key":"10.1016\/j.bbmt.2011.02.012_bib15","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1182\/blood-2004-12-4988","article-title":"BK DNA viral load in plasma: evidence for an association with hemorrhagic cystitis in allogeneic hematopoietic cell transplant recipients","volume":"106","author":"Erard","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2011.02.012_bib16","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1016\/j.bbmt.2009.04.016","article-title":"BK virus infection is associated with hematuria and renal impairment in recipients of allogeneic hematopoetic stem cell transplants","volume":"15","author":"O\u2019Donnell","year":"2009","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2011.02.012_bib17","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1097\/00007890-197410000-00001","article-title":"Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-A-matched sibling donors","volume":"18","author":"Glucksberg","year":"1974","journal-title":"Transplantation"},{"key":"10.1016\/j.bbmt.2011.02.012_bib18","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.bbmt.2005.06.001","article-title":"Blood and marrow transplant clinical trials network toxicity committee consensus summary: thrombotic microangiopathy after hematopoietic stem cell transplantation","volume":"11","author":"Ho","year":"2005","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2011.02.012_bib19","doi-asserted-by":"crossref","first-page":"95","DOI":"10.3324\/haematol.10699","article-title":"Diagnostic criteria for hematopoietic stem cell transplant-associated microangiopathy: results of a consensus process by an International Working Group","volume":"92","author":"Ruutu","year":"2007","journal-title":"Haematologica"},{"key":"10.1016\/j.bbmt.2011.02.012_bib20","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/bmt.2008.198","article-title":"BK virus encephalitis in an allogeneic hematopoietic stem cell recipient","volume":"42","author":"Behre","year":"2008","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2011.02.012_bib21","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/sj.bmt.1705886","article-title":"Polyomavirus BK infection in blood and marrow transplant recipients","volume":"41","author":"Dropulic","year":"2008","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2011.02.012_bib22","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1038\/sj.bmt.1700849","article-title":"BK papova virus pneumonia following hematopoietic stem cell transplantation","volume":"20","author":"Sandler","year":"1997","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2011.02.012_bib23","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1038\/sj.bmt.1705139","article-title":"Polyoma BK virus and haemorrhagic cystitis in haematopoietic stem cell transplantation: a changing paradigm","volume":"36","author":"Leung","year":"2005","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2011.02.012_bib24","doi-asserted-by":"crossref","first-page":"5394","DOI":"10.1128\/JCM.42.11.5394-5396.2004","article-title":"Association between a high BK virus load in urine samples of patients with graft-versus-host disease and development of hemorrhagic cystitis after hematopoietic stem cell transplantation","volume":"42","author":"Bogdanovic","year":"2004","journal-title":"J Clin Microbio"},{"key":"10.1016\/j.bbmt.2011.02.012_bib25","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1097\/01.TP.0000061767.32870.72","article-title":"Polyomavirus BK infection in pediatric kidney-allograft recipients: a single-center analysis of incidence, risk factors, and novel therapeutic approaches","volume":"75","author":"Ginevri","year":"2003","journal-title":"Transplantation"},{"key":"10.1016\/j.bbmt.2011.02.012_bib26","doi-asserted-by":"crossref","first-page":"2227","DOI":"10.2165\/11319260-000000000-00000","article-title":"Immunosuppressive drugs in kidney transplantation: impact on patient survival, and incidence of cardiovascular disease, malignancy and infection","volume":"69","author":"Marcen","year":"2009","journal-title":"Drugs"},{"key":"10.1016\/j.bbmt.2011.02.012_bib27","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.1182\/blood.V98.6.1971","article-title":"Quantification of polyoma BK viruria in hemorrhagic cystitis complicating bone marrow transplantation","volume":"98","author":"Leung","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2011.02.012_bib28","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1056\/NEJM200005043421802","article-title":"Testing for polyomavirus type BK DNA in plasma to identify renal-allograft recipients with viral nephropathy","volume":"342","author":"Nickeleit","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.bbmt.2011.02.012_bib29","doi-asserted-by":"crossref","first-page":"345","DOI":"10.2215\/CJN.02070508","article-title":"Renal thrombotic microangiopathy after hematopoietic cell transplant: role of GVHD in pathogenesis","volume":"4","author":"Changsirikulchai","year":"2009","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.bbmt.2011.02.012_bib30","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1097\/01.tp.0000230373.82376.46","article-title":"Risk factors and severe outcome in thrombotic microangiopathy after allogeneic hematopoietic stem cell transplantation","volume":"82","author":"Uderzo","year":"2006","journal-title":"Transplantation"},{"key":"10.1016\/j.bbmt.2011.02.012_bib31","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1038\/bmt.2009.230","article-title":"Comparison of thrombotic microangiopathy after allogeneic hematopoietic cell transplantation with high-dose or nonmyeloablative conditioning","volume":"45","author":"Willems","year":"2010","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2011.02.012_bib32","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1038\/sj.bmt.1702003","article-title":"Thrombotic microangiopathy associated with reactivation of human herpesvirus-6 following high-dose chemotherapy with autologous bone marrow transplantation in young children","volume":"24","author":"Matsuda","year":"1999","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2011.02.012_bib33","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1007\/s00467-007-0616-x","article-title":"The thrombotic microangiopathies","volume":"23","author":"Copelovitch","year":"2008","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.bbmt.2011.02.012_bib34","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.2215\/CJN.01700407","article-title":"Spectrum of renal pathology in hematopoietic cell transplantation: a series of 20 patients and review of the literature","volume":"2","author":"Chang","year":"2007","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.bbmt.2011.02.012_bib35","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1399-3062.2010.00581.x","article-title":"BK virus encephalitis with thrombotic microangiopathy in an allogeneic hematopoietic stem cell transplant recipient","volume":"13","author":"Lopes da Silva","year":"2011","journal-title":"Transpl Infect Dis"},{"key":"10.1016\/j.bbmt.2011.02.012_bib36","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/j.1399-3046.2005.00391.x","article-title":"Intermediate-dose cidofovir without probenecid in the treatment of BK virus allograft nephropathy","volume":"10","author":"Araya","year":"2006","journal-title":"Pediatr Transplant"},{"key":"10.1016\/j.bbmt.2011.02.012_bib37","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1111\/j.1399-3046.2008.00937.x","article-title":"Intermediate dose cidofovir does not cause additive nephrotoxicity in BK virus allograft nephropathy","volume":"12","author":"Araya","year":"2008","journal-title":"Pediatr Transplant"},{"key":"10.1016\/j.bbmt.2011.02.012_bib38","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1111\/j.1399-3062.2010.00513.x","article-title":"Low-dose cidofovir in the treatment of symptomatic BK virus infection in patients undergoing allogeneic hematopoietic stem cell transplantation: a retrospective analysis of an algorithmic approach","volume":"12","author":"Ganguly","year":"2010","journal-title":"Transpl Infect Dis"},{"key":"10.1016\/j.bbmt.2011.02.012_bib39","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1038\/sj.bmt.1705678","article-title":"Low-dose cidofovir treatment of BK virus-associated hemorrhagic cystitis in recipients of hematopoietic stem cell transplant","volume":"39","author":"Savona","year":"2007","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2011.02.012_bib40","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1097\/TP.0b013e3181d0e15e","article-title":"Treatment of polyomavirus infection in kidney transplant recipients: a systematic review","volume":"89","author":"Johnston","year":"2010","journal-title":"Transplantation"},{"key":"10.1016\/j.bbmt.2011.02.012_bib41","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/j.1600-6143.2005.01152.x","article-title":"Concurrent antiviral and immunosuppressive activities of leflunomide in vivo","volume":"6","author":"Chong","year":"2006","journal-title":"Am J Transplant"},{"key":"10.1016\/j.bbmt.2011.02.012_bib42","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1055\/s-2006-933412","article-title":"Treatment of refractory CMV-infection following hematopoietic stem cell transplantation with the combination of foscarnet and leflunomide","volume":"218","author":"Ehlert","year":"2006","journal-title":"Klin Padiatr"},{"key":"10.1016\/j.bbmt.2011.02.012_bib43","doi-asserted-by":"crossref","first-page":"829","DOI":"10.2215\/CJN.03930907","article-title":"Higher levels of leflunomide are associated with hemolysis and are not superior to lower levels for BK virus clearance in renal transplant patients","volume":"3","author":"Leca","year":"2008","journal-title":"Clin J Am Soc Nephrol"}],"container-title":["Biology of Blood and Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083879111001200?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083879111001200?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T14:39:16Z","timestamp":1761057556000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1083879111001200"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10]]},"references-count":43,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2011,10]]}},"alternative-id":["S1083879111001200"],"URL":"https:\/\/doi.org\/10.1016\/j.bbmt.2011.02.012","relation":{},"ISSN":["1083-8791"],"issn-type":[{"value":"1083-8791","type":"print"}],"subject":[],"published":{"date-parts":[[2011,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Blood, and Not Urine, BK Viral Load Predicts Renal Outcome in Children with Hemorrhagic Cystitis following Hematopoietic Stem Cell Transplantation","name":"articletitle","label":"Article Title"},{"value":"Biology of Blood and Marrow Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbmt.2011.02.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 American Society for Blood and Marrow Transplantation. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}