{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T13:34:40Z","timestamp":1765805680966,"version":"build-2065373602"},"reference-count":56,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2015,4,10]],"date-time":"2015-04-10T00:00:00Z","timestamp":1428624000000},"content-version":"vor","delay-in-days":1013,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["bbmt.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biology of Blood and Marrow Transplantation"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1016\/j.bbmt.2012.05.002","type":"journal-article","created":{"date-parts":[[2012,5,9]],"date-time":"2012-05-09T21:52:54Z","timestamp":1336600374000},"page":"1023-1035","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Histological Assessment of the Sclerotic Graft-versus-Host Response in the Humanized RAG2\u2212\/\u2212\u03b3c\u2212\/\u2212 Mouse Model"],"prefix":"10.1016","volume":"18","author":[{"given":"Marieke C.H.","family":"Hogenes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne","family":"van Dorp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joyce","family":"van Kuik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filipa R.P.","family":"Monteiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie","family":"ter Hoeve","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marijke R.","family":"van Dijk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anton C.","family":"Martens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roel A.","family":"de Weger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbmt.2012.05.002_bib1","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/sj.bmt.1704410","article-title":"Chronic graft-versus-host disease: where do we go from here?","volume":"33","author":"Farag","year":"2004","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2012.05.002_bib2","series-title":"Thomas' Hematopoietic Cell Transplantation","first-page":"353","article-title":"The pathophysiology of graft-vs-host disease","author":"Ferrara","year":"2004"},{"key":"10.1016\/j.bbmt.2012.05.002_bib3","doi-asserted-by":"crossref","first-page":"4200","DOI":"10.1182\/blood-2004-10-4023","article-title":"New approaches for preventing and treating chronic graft-versus-host disease","volume":"105","author":"Lee","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2012.05.002_bib4","doi-asserted-by":"crossref","first-page":"2603","DOI":"10.1182\/blood-2004-05-1855","article-title":"Anti-CD20 monoclonal antibody treatment in 6 patients with therapy-refractory chronic graft-versus-host disease","volume":"104","author":"Canninga-van Dijk","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2012.05.002_bib5","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1002\/eji.200838433","article-title":"Mesenchymal stem cells for graft-versus-host disease: close encounters with T cells","volume":"38","author":"Dazzi","year":"2008","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.bbmt.2012.05.002_bib6","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.jaci.2008.01.004","article-title":"Human immature myeloid dendritic cells trigger a TH2-polarizing program via Jagged-1\/Notch interaction","volume":"121","author":"Liotta","year":"2008","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.bbmt.2012.05.002_bib7","first-page":"516","article-title":"Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory\/suppressive phenotype","volume":"90","author":"Maccario","year":"2005","journal-title":"Haematologica"},{"key":"10.1016\/j.bbmt.2012.05.002_bib8","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.cellimm.2008.04.009","article-title":"The immunosuppressive effects of human bone marrow\u2013derived mesenchymal stem cells target T cell proliferation but not its effector function","volume":"251","author":"Ramasamy","year":"2008","journal-title":"Cell Immunol"},{"key":"10.1016\/j.bbmt.2012.05.002_bib9","doi-asserted-by":"crossref","first-page":"4919","DOI":"10.1182\/blood-2008-10-161638","article-title":"The role of B cells in the pathogenesis of graft-versus-host disease","volume":"114","author":"Shimabukuro-Vornhagen","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2012.05.002_bib10","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1007\/s00011-008-7234-3","article-title":"Regulatory CD4+CD25+ T cells and macrophages: communication between two regulators of effector T cells","volume":"57","author":"Zhen","year":"2008","journal-title":"Inflamm Res"},{"key":"10.1016\/j.bbmt.2012.05.002_bib11","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1097\/00007890-200107150-00026","article-title":"Patterns of engraftment in different strains of immunodeficient mice reconstituted with human peripheral blood lymphocytes","volume":"72","author":"Berney","year":"2001","journal-title":"Transplantation"},{"key":"10.1016\/j.bbmt.2012.05.002_bib12","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1046\/j.1365-2141.1998.00980.x","article-title":"Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor gamma chain","volume":"103","author":"Goldman","year":"1998","journal-title":"Br J Haematol"},{"key":"10.1016\/j.bbmt.2012.05.002_bib13","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1182\/blood.V83.8.2368.2368","article-title":"Engraftment of human peripheral blood lymphocytes in normal strains of mice","volume":"83","author":"Lubin","year":"1994","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2012.05.002_bib14","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/335256a0","article-title":"Transfer of a functional human immune system to mice with severe combined immunodeficiency","volume":"335","author":"Mosier","year":"1988","journal-title":"Nature"},{"key":"10.1016\/j.bbmt.2012.05.002_bib15","doi-asserted-by":"crossref","first-page":"2522","DOI":"10.1182\/blood-2002-10-3241","article-title":"A new xenograft model for graft-versus-host disease by intravenous transfer of human peripheral blood mononuclear cells in RAG2-\/-\u03b3-\/- double-mutant mice","volume":"102","author":"van Rijn","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2012.05.002_bib16","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1182\/blood-2005-02-0516","article-title":"Development of functional human blood and immune systems in NOD\/SCID\/IL2 receptor \u03b3 chainnull mice","volume":"106","author":"Ishikawa","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2012.05.002_bib17","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1126\/science.2971269","article-title":"The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function","volume":"241","author":"McCune","year":"1988","journal-title":"Science"},{"key":"10.1016\/j.bbmt.2012.05.002_bib18","doi-asserted-by":"crossref","unstructured":"McDermott SP, Eppert K, Lechman ER, et\u00a0al. Comparison of human cord blood engraftment between immunocompromised mouse strains. Blood. XXXX;116:193\u2013200.","DOI":"10.1182\/blood-2010-02-271841"},{"key":"10.1016\/j.bbmt.2012.05.002_bib19","doi-asserted-by":"crossref","first-page":"6477","DOI":"10.4049\/jimmunol.174.10.6477","article-title":"Human lymphoid and myeloid cell development in NOD\/LtSz-scid IL2R\u03b3null mice engrafted with mobilized human hemopoietic stem cells","volume":"174","author":"Shultz","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.bbmt.2012.05.002_bib20","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/0167-5699(95)80046-8","article-title":"The human immune system in hu-PBL-SCID mice","volume":"16","author":"Tary-Lehmann","year":"1995","journal-title":"Immunol Today"},{"key":"10.1016\/j.bbmt.2012.05.002_bib21","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1097\/TP.0b013e3181a5cb07","article-title":"Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice","volume":"87","author":"Ito","year":"2009","journal-title":"Transplantation"},{"key":"10.1016\/j.bbmt.2012.05.002_bib22","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1111\/j.1365-2249.2009.03933.x","article-title":"Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor \u03b3 chain gene mouse model of xenogeneic graft-versus-host\u2013like disease and the role of host major histocompatibility complex","volume":"157","author":"King","year":"2009","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.bbmt.2012.05.002_bib23","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1016\/j.exphem.2007.06.007","article-title":"Factors affecting human T cell engraftment, trafficking, and associated xenogeneic graft-vs-host disease in NOD\/SCID \u03b22mnull mice","volume":"35","author":"Nervi","year":"2007","journal-title":"Exp Hematol"},{"key":"10.1016\/j.bbmt.2012.05.002_bib24","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1093\/infdis\/168.3.630","article-title":"Human peripheral blood xenografts in the SCID mouse: characterization of immunologic reconstitution","volume":"168","author":"Hesselton","year":"1993","journal-title":"J Infect Dis"},{"key":"10.1016\/j.bbmt.2012.05.002_bib25","doi-asserted-by":"crossref","first-page":"3440","DOI":"10.1182\/blood.V81.12.3440.3440","article-title":"Immunohistology and immunocytology of human T-cell chimerism and graft-versus-host disease in SCID mice","volume":"81","author":"Hoffmann-Fezer","year":"1993","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2012.05.002_bib26","doi-asserted-by":"crossref","first-page":"2752","DOI":"10.1182\/blood.V99.8.2752","article-title":"Intrathymic and extrathymic development of human plasmacytoid dendritic cell precursors in\u00a0vivo","volume":"99","author":"Weijer","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2012.05.002_bib27","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1111\/j.1600-6143.2008.02198.x","article-title":"T cells in cardiac allograft vasculopathy are skewed to memory Th-1 cells in the presence of a distinct Th-2 population","volume":"8","author":"Hagemeijer","year":"2008","journal-title":"Am J Transplant"},{"key":"10.1016\/j.bbmt.2012.05.002_bib28","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1111\/j.1537-2995.2006.00939.x","article-title":"Mirasol PRT treatment of donor white blood cells prevents the development of xenogeneic graft-versus-host disease in Rag2-\/-\u03b3c-\/- double-knockout mice","volume":"46","author":"Fast","year":"2006","journal-title":"Transfusion"},{"key":"10.1016\/j.bbmt.2012.05.002_bib29","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1242\/dmm.006668","article-title":"Mouse models of graft-versus-host disease: advances and limitations","volume":"4","author":"Schroeder","year":"2011","journal-title":"Dis Model Mech"},{"key":"10.1016\/j.bbmt.2012.05.002_bib30","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/0008-8749(85)90086-3","article-title":"Chronic graft-versus-host disease as a model for scleroderma, II: mast cell depletion with deposition of immunoglobulins in the skin and fibrosis","volume":"94","author":"Claman","year":"1985","journal-title":"Cell Immunol"},{"key":"10.1016\/j.bbmt.2012.05.002_bib31","doi-asserted-by":"crossref","first-page":"476","DOI":"10.4049\/jimmunol.143.2.476","article-title":"Hepatic homing of mononuclear inflammatory cells isolated during murine chronic graft-vs-host disease","volume":"143","author":"Howell","year":"1989","journal-title":"J Immunol"},{"key":"10.1016\/j.bbmt.2012.05.002_bib32","doi-asserted-by":"crossref","first-page":"5693","DOI":"10.4049\/jimmunol.163.10.5693","article-title":"Anti\u2013TGF-\u03b2 treatment prevents skin and lung fibrosis in murine sclerodermatous graft-versus-host disease: a model for human scleroderma","volume":"163","author":"McCormick","year":"1999","journal-title":"J Immunol"},{"key":"10.1016\/j.bbmt.2012.05.002_bib33","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.bbmt.2007.12.002","article-title":"Murine models of chronic graft-versus-host disease: insights and unresolved issues","volume":"14","author":"Chu","year":"2008","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2012.05.002_bib34","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1097\/00007890-199805270-00014","article-title":"In\u00a0vivo alloreactive potential of ex\u00a0vivo\u2013expanded primary T lymphocytes","volume":"65","author":"Contassot","year":"1998","journal-title":"Transplantation"},{"key":"10.1016\/j.bbmt.2012.05.002_bib35","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1172\/JCI9920","article-title":"Cytokines and the regulation of tolerance","volume":"105","author":"Ferrara","year":"2000","journal-title":"J Clin Invest"},{"key":"10.1016\/j.bbmt.2012.05.002_bib36","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/00000478-199701000-00003","article-title":"Immunohistochemical study of skin lesions in acute and chronic graft-versus-host disease following bone marrow transplantation","volume":"21","author":"Favre","year":"1997","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.bbmt.2012.05.002_bib37","doi-asserted-by":"crossref","first-page":"3620","DOI":"10.1182\/blood-2008-07-168351","article-title":"Increased T-bet+ cytotoxic effectors and type I interferon\u2013mediated processes in chronic graft-versus-host disease of the oral mucosa","volume":"113","author":"Imanguli","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2012.05.002_bib38","first-page":"209","article-title":"Demonstration of direct involvement of cytokines in graft-versus-host reactions using an in\u00a0vitro human skin explant model","volume":"7","author":"Dickinson","year":"1991","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2012.05.002_bib39","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/S0171-2985(99)80051-5","article-title":"The role of intestinal bacterial flora in the tuning of the T cell repertoire","volume":"201","author":"Sawamura","year":"1999","journal-title":"Immunobiology"},{"key":"10.1016\/j.bbmt.2012.05.002_bib40","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/sj.bmt.1703386","article-title":"Progressive interstitial fibrosis of the lung in sclerodermoid chronic graft-versus-host disease","volume":"29","author":"Wolff","year":"2002","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2012.05.002_bib41","doi-asserted-by":"crossref","first-page":"3903","DOI":"10.1182\/blood-2002-03-0857","article-title":"Hepatitic variant of graft-versus-host disease after donor lymphocyte infusion","volume":"100","author":"Akpek","year":"2002","journal-title":"Blood"},{"issue":"1 Pt 2","key":"10.1016\/j.bbmt.2012.05.002_bib42","first-page":"1250","article-title":"Graft-versus-host disease: liver morphology and pheno\/genotypes of inflammatory cells and target cells in sex-mismatched allogeneic bone marrow transplant patients","volume":"25","author":"Andersen","year":"1993","journal-title":"Transplant Proc"},{"key":"10.1016\/j.bbmt.2012.05.002_bib43","first-page":"319","article-title":"Severe isolated acute hepatic graft-versus-host disease with vanishing bile duct syndrome","volume":"14","author":"Yeh","year":"1994","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2012.05.002_bib44","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/BF02982546","article-title":"Cytokines in graft-versus-host disease and the graft-versus-leukemia reaction","volume":"74","author":"Deeg","year":"2001","journal-title":"Int J Hematol"},{"key":"10.1016\/j.bbmt.2012.05.002_bib45","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1002\/1529-0131(200102)44:2<474::AID-ANR67>3.0.CO;2-#","article-title":"Blockade of endogenous transforming growth factor \u03b2 signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: association with increased expression of transforming growth factor \u03b2 receptors","volume":"44","author":"Ihn","year":"2001","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.bbmt.2012.05.002_bib46","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1002\/1529-0131(200103)44:3<731::AID-ANR124>3.0.CO;2-U","article-title":"Up-regulated expression of transforming growth factor \u03b2 receptors in dermal fibroblasts in skin sections from patients with localized scleroderma","volume":"44","author":"Kubo","year":"2001","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.bbmt.2012.05.002_bib47","doi-asserted-by":"crossref","first-page":"3478","DOI":"10.1002\/art.22877","article-title":"T cells expressing allograft inflammatory factor 1 display increased chemotaxis and induce a profibrotic phenotype in normal fibroblasts in\u00a0vitro","volume":"56","author":"Del Galdo","year":"2007","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.bbmt.2012.05.002_bib48","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1046\/j.1523-1747.2003.12517.x","article-title":"Latency-associated peptide prevents skin fibrosis in murine sclerodermatous graft-versus-host disease, a model for human scleroderma","volume":"121","author":"Zhang","year":"2003","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.bbmt.2012.05.002_bib49","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1111\/1523-1747.ep12345771","article-title":"Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders","volume":"106","author":"Igarashi","year":"1996","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.bbmt.2012.05.002_bib50","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1111\/1523-1747.ep12318465","article-title":"Significant correlation between connective tissue growth factor gene expression and skin sclerosis in tissue sections from patients with systemic sclerosis","volume":"105","author":"Igarashi","year":"1995","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.bbmt.2012.05.002_bib51","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1038\/modpathol.2010.48","article-title":"CD20, AIF-1, and TGF-\u03b2 in\u00a0graft-versus-host disease: a study of mRNA expression in histologically matched skin biopsies","volume":"23","author":"Wu","year":"2010","journal-title":"Mod Pathol"},{"key":"10.1016\/j.bbmt.2012.05.002_bib52","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1172\/JCI3906","article-title":"Differential effects of the absence of interferon-\u03b3 and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice","volume":"102","author":"Murphy","year":"1998","journal-title":"J Clin Invest"},{"key":"10.1016\/j.bbmt.2012.05.002_bib53","doi-asserted-by":"crossref","first-page":"3558","DOI":"10.1182\/blood.V93.10.3558.410k31_3558_3564","article-title":"Prevention of graft-versus-host disease by induction of immune tolerance with ultraviolet B-irradiated leukocytes in H-2 disparate bone marrow donor","volume":"93","author":"del Rosario","year":"1999","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2012.05.002_bib54","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1038\/sj.bmt.1701478","article-title":"IFN-\u03b3\u2013mediated prevention of graft-versus-host disease: pharmacodynamic studies and influence on proliferative capacity of chimeric spleen cells","volume":"22","author":"Brok","year":"1998","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2012.05.002_bib55","doi-asserted-by":"crossref","first-page":"4651","DOI":"10.1182\/blood.V90.11.4651","article-title":"Interleukin-12 preserves the graft-versus-leukemia effect of allogeneic CD8 T cells while inhibiting CD4-dependent graft-versus-host disease in mice","volume":"90","author":"Yang","year":"1997","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2012.05.002_bib56","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1097\/TP.0b013e318183eefa","article-title":"Amelioration of human allograft arterial injury by atorvastatin or simvastatin correlates with reduction of interferon-\u03b3 production by infiltrating T cells","volume":"86","author":"Yi","year":"2008","journal-title":"Transplantation"}],"container-title":["Biology of Blood and Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083879112001802?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083879112001802?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T14:41:03Z","timestamp":1761057663000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1083879112001802"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":56,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["S1083879112001802"],"URL":"https:\/\/doi.org\/10.1016\/j.bbmt.2012.05.002","relation":{},"ISSN":["1083-8791"],"issn-type":[{"type":"print","value":"1083-8791"}],"subject":[],"published":{"date-parts":[[2012,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Histological Assessment of the Sclerotic Graft-versus-Host Response in the Humanized RAG2\u2212\/\u2212\u03b3c\u2212\/\u2212 Mouse Model","name":"articletitle","label":"Article Title"},{"value":"Biology of Blood and Marrow Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbmt.2012.05.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 American Society for Blood and Marrow Transplantation. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}