{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T08:01:04Z","timestamp":1779264064955,"version":"3.51.4"},"reference-count":64,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007052","name":"Memorial Sloan Kettering Cancer Center","doi-asserted-by":"publisher","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}],"id":[{"id":"10.13039\/100007052","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Clinical and Translational Science Center at Weill Cornell","award":["KL2 TR000458"],"award-info":[{"award-number":["KL2 TR000458"]}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K05 CA160724"],"award-info":[{"award-number":["K05 CA160724"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bbmt.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biology of Blood and Marrow Transplantation"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1016\/j.bbmt.2016.12.623","type":"journal-article","created":{"date-parts":[[2016,12,28]],"date-time":"2016-12-28T04:30:17Z","timestamp":1482899417000},"page":"475-482","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Cardiovascular Risk Factors in Survivors of Childhood Hematopoietic Cell Transplantation Treated with Total Body Irradiation: A Longitudinal Analysis"],"prefix":"10.1016","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4668-9176","authenticated-orcid":false,"given":"Danielle Novetsky","family":"Friedman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Hilden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaya S.","family":"Moskowitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0573-8795","authenticated-orcid":false,"given":"Maya","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farid","family":"Boulad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy A.","family":"Kernan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne L.","family":"Wolden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin C.","family":"Oeffinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1702-5031","authenticated-orcid":false,"given":"Charles A.","family":"Sklar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbmt.2016.12.623_bib0010","doi-asserted-by":"crossref","first-page":"3784","DOI":"10.1182\/blood-2007-03-082933","article-title":"Late mortality after allogeneic hematopoietic cell transplantation and functional status of long-term survivors: report from the Bone Marrow Transplant Survivor Study","volume":"110","author":"Bhatia","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0015","doi-asserted-by":"crossref","first-page":"4215","DOI":"10.1182\/blood-2005-01-0035","article-title":"Late mortality in survivors of autologous hematopoietic-cell transplantation: report from the Bone Marrow Transplant Survivor Study","volume":"105","author":"Bhatia","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0020","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1056\/NEJMra052638","article-title":"Hematopoietic stem-cell transplantation","volume":"354","author":"Copelan","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0025","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1016\/j.bbmt.2011.07.005","article-title":"NCI, NHLBI first international consensus conference on late effects after pediatric hematopoietic cell transplantation: etiology and pathogenesis of late effects after HCT performed in childhood: methodologic challenges","volume":"17","author":"Bhatia","year":"2011","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0030","doi-asserted-by":"crossref","first-page":"3129","DOI":"10.1182\/blood-2009-06-229369","article-title":"Prevalence and predictors of chronic health conditions after hematopoietic cell transplantation: a report from the Bone Marrow Transplant Survivor Study","volume":"116","author":"Sun","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0035","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.bbmt.2013.04.002","article-title":"Burden of morbidity in 10+-year survivors of hematopoietic cell transplantation: report from the bone marrow transplantation survivor study","volume":"19","author":"Sun","year":"2013","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0040","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1182\/blood-2011-01-331835","article-title":"Long-term health-related outcomes in survivors of childhood cancer treated with HSCT versus conventional therapy: a report from the Bone Marrow Transplant Survivor Study (BMTSS) and Childhood Cancer Survivor Study (CCSS)","volume":"118","author":"Armenian","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0045","doi-asserted-by":"crossref","first-page":"4505","DOI":"10.1182\/blood-2012-06-437178","article-title":"Cardiovascular risk factors in hematopoietic cell transplantation survivors: role in development of subsequent cardiovascular disease","volume":"120","author":"Armenian","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0050","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1016\/S0140-6736(00)02717-3","article-title":"Impaired glucose tolerance and dyslipidaemia as late effects after bone-marrow transplantation in childhood","volume":"356","author":"Taskinen","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0055","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1038\/bmt.2015.43","article-title":"Adverse health events and late mortality after pediatric allogeneic hematopoietic SCT\u2013two decades of longitudinal follow-up","volume":"50","author":"Wilhelmsson","year":"2015","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0060","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/s10654-010-9496-7","article-title":"Metabolic syndrome and all-cause mortality: a meta-analysis of prospective cohort studies","volume":"25","author":"Wu","year":"2010","journal-title":"Eur J Epidemiol"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0065","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/j.amjmed.2006.02.031","article-title":"Metabolic syndrome and risk of cardiovascular disease: a meta-analysis","volume":"119","author":"Galassi","year":"2006","journal-title":"Am J Med"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0070","doi-asserted-by":"crossref","first-page":"e6","DOI":"10.1007\/BF03346702","article-title":"A comparison between metabolic syndrome post-hematopoietic stem cell transplantation and spontaneously occurring metabolic syndrome","volume":"34","author":"Airaghi","year":"2011","journal-title":"J Endocrinol Invest"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0075","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1038\/bmt.2011.118","article-title":"Metabolic syndrome and cardiovascular risk in survivors after hematopoietic cell transplantation","volume":"47","author":"Baker","year":"2012","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0080","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1182\/blood-2006-05-022335","article-title":"Diabetes, hypertension, and cardiovascular events in survivors of hematopoietic cell transplantation: a report from the bone marrow transplantation survivor study","volume":"109","author":"Baker","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0085","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1038\/sj.bmt.1704481","article-title":"Disturbances of growth and endocrine function after busulphan-based conditioning for haematopoietic stem cell transplantation during infancy and childhood","volume":"33","author":"Bakker","year":"2004","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0090","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1002\/pbc.25603","article-title":"Early and progressive insulin resistance in young, non-obese cancer survivors treated with hematopoietic stem cell transplantation","volume":"62","author":"Bizzarri","year":"2015","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0095","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/bmt.2008.263","article-title":"High prevalence of metabolic syndrome after allogeneic hematopoietic cell transplantation","volume":"43","author":"Majhail","year":"2009","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0100","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1002\/cncr.10773","article-title":"High prevalence of endocrine dysfunction in long-term survivors after allogeneic bone marrow transplantation for hematologic diseases","volume":"95","author":"Tauchmanov\u00e0","year":"2002","journal-title":"Cancer"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0105","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1038\/sj.bmt.1705374","article-title":"Endocrine dysfunction and parameters of the metabolic syndrome after bone marrow transplantation during childhood and adolescence","volume":"37","author":"Shalitin","year":"2006","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0110","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1111\/petr.12002","article-title":"Metabolic syndrome and endocrine dysfunctions after HSCT in children","volume":"16","author":"Bajwa","year":"2012","journal-title":"Pediatr Transplant"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0115","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1002\/pbc.24104","article-title":"Evaluation of metabolic syndrome after hematopoietic stem cell transplantation in children and adolescents","volume":"59","author":"Paris","year":"2012","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0120","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1016\/j.bbmt.2010.05.016","article-title":"Increased cardiometabolic traits in pediatric survivors of acute lymphoblastic leukemia treated with total body irradiation","volume":"16","author":"Chow","year":"2010","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0125","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1002\/pbc.24252","article-title":"Late effects of total body irradiation and hematopoietic stem cell transplant in children under 3 years of age","volume":"60","author":"Mulcahy Levy","year":"2013","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0130","doi-asserted-by":"crossref","first-page":"4401","DOI":"10.1210\/jc.2006-0128","article-title":"Hyperinsulinemia, impaired glucose tolerance, and diabetes mellitus in survivors of childhood cancer: prevalence and risk factors","volume":"91","author":"Neville","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0135","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1038\/bmt.2010.307","article-title":"Glucose metabolism and body composition in young adults treated with TBI during childhood","volume":"46","author":"Frisk","year":"2011","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0145","first-page":"825","article-title":"1994 Consensus Conference on Acute GVHD Grading","volume":"15","author":"Przepiorka","year":"1995","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0150","first-page":"250","article-title":"Chronic graft-versus-host disease and other late complications of bone marrow transplantation","volume":"28","author":"Sullivan","year":"1991","journal-title":"Semin Hematol"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0155","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1464-5491.2006.01858.x","article-title":"Metabolic syndrome: a new world-wide definition. A consensus statement from the International Diabetes Federation","volume":"23","author":"Alberti","year":"2006","journal-title":"Diabet Med"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0160","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1158\/1055-9965.EPI-09-0555","article-title":"Cardiovascular risk factors in adult survivors of pediatric cancer: a report from the Childhood Cancer Survivor Study","volume":"19","author":"Meacham","year":"2010","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0165","doi-asserted-by":"crossref","first-page":"8473","DOI":"10.1158\/0008-5472.CAN-08-0131","article-title":"Nicotine promotes mammary tumor migration via a signaling cascade involving protein kinase C and CDC42","volume":"68","author":"Guo","year":"2008","journal-title":"Cancer Res"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0170","first-page":"555","article-title":"The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents","volume":"114(2 Suppl 4th Report)","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0175","series-title":"The statistical analysis of failure time data","author":"Kalbfleisch","year":"2002"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0180","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1200\/JCO.2013.52.6582","article-title":"Influence of conventional cardiovascular risk factors and lifestyle characteristics on cardiovascular disease after hematopoietic cell transplantation","volume":"32","author":"Chow","year":"2014","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0185","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.2337\/diacare.28.7.1769","article-title":"Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome: a summary of the evidence","volume":"28","author":"Ford","year":"2005","journal-title":"Diabetes Care"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0190","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/j.bbmt.2014.02.012","article-title":"Late cardiovascular complications after hematopoietic cell transplantation","volume":"20","author":"Chow","year":"2014","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0195","doi-asserted-by":"crossref","first-page":"3673","DOI":"10.1200\/JCO.2013.49.3205","article-title":"Modifiable risk factors and major cardiac events among adult survivors of childhood cancer","volume":"31","author":"Armstrong","year":"2013","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0200","doi-asserted-by":"crossref","first-page":"4442","DOI":"10.1182\/blood-2010-09-304899","article-title":"Prevalence and risk factors of the metabolic syndrome in adult survivors of childhood leukemia","volume":"117","author":"Oudin","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0205","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1002\/pbc.21207","article-title":"Long-term follow-up of children who underwent hematopoeitic cell transplant (HCT) for AML or ALL at less than 3 years of age","volume":"49","author":"Perkins","year":"2007","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0210","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1046\/j.1365-2265.1999.00622.x","article-title":"Hyperleptinaemia in young adults following cranial irradiation in childhood: growth hormone deficiency or leptin insensitivity?","volume":"50","author":"Brennan","year":"1999","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0215","doi-asserted-by":"crossref","first-page":"2138","DOI":"10.1210\/en.2007-1200","article-title":"Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome","volume":"149","author":"Bingham","year":"2008","journal-title":"Endocrinology"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0220","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.cell.2008.07.043","article-title":"Hypothalamic IKKbeta\/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity","volume":"135","author":"Zhang","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0225","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jnutbio.2015.09.002","article-title":"An assessment of molecular pathways of obesity susceptible to nutrient, toxicant and genetically induced epigenetic perturbation","volume":"30","author":"Xue","year":"2016","journal-title":"J Nutr Biochem"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0230","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.bbmt.2009.11.018","article-title":"Hypertension in long-term survivors of pediatric hematopoietic cell transplantation","volume":"16","author":"Hoffmeister","year":"2010","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0235","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1002\/cncr.22120","article-title":"Metabolic syndrome and growth hormone deficiency in adult survivors of childhood acute lymphoblastic leukemia","volume":"107","author":"Gurney","year":"2006","journal-title":"Cancer"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0240","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1038\/bmt.2015.167","article-title":"Metabolic syndrome in adults who received hematopoietic stem cell transplantation for acute childhood leukemia: an LEA study","volume":"50","author":"Oudin","year":"2015","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0245","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1097\/MPH.0b013e3180f61b67","article-title":"Insufficient growth hormone secretion is associated with metabolic syndrome after allogeneic stem cell transplantation in childhood","volume":"29","author":"Taskinen","year":"2007","journal-title":"J Pediatr Hematol Oncol"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0250","first-page":"3051","article-title":"Long-term survivors of childhood cancer have an increased risk of manifesting the metabolic syndrome","volume":"81","author":"Talvensaari","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"issue":"Suppl A","key":"10.1016\/j.bbmt.2016.12.623_bib0255","doi-asserted-by":"crossref","first-page":"S62","DOI":"10.1016\/j.ghir.2006.03.004","article-title":"Visceral obesity, impaired glucose tolerance, metabolic syndrome, and growth hormone therapy","volume":"16","author":"Attallah","year":"2006","journal-title":"Growth Horm IGF Res"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0260","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0953-6205(03)00022-0","article-title":"Abdominal obesity, insulin resistance, and metabolic syndrome in a southern European population","volume":"14","author":"Ascaso","year":"2003","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0265","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1002\/pbc.25601","article-title":"Reduced insulin sensitivity in childhood survivors of haematopoietic stem cell transplantation is associated with lipodystropic and sarcopenic phenotypes","volume":"62","author":"Wei","year":"2015","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0270","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.3945\/ajcn.2008.26546","article-title":"Visceral adiposity and its anatomical distribution as predictors of the metabolic syndrome and cardiometabolic risk factor levels","volume":"88","author":"Demerath","year":"2008","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0275","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.jpeds.2011.06.041","article-title":"Body composition abnormalities in long-term survivors of pediatric hematopoietic stem cell transplantation","volume":"160","author":"Mostoufi-Moab","year":"2012","journal-title":"J Pediatr"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0280","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1002\/jbmr.2512","article-title":"Adverse fat depots and marrow adiposity are associated with skeletal deficits and insulin resistance in long-term survivors of pediatric hematopoietic stem cell transplantation","volume":"30","author":"Mostoufi-Moab","year":"2015","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0285","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1002\/cncr.20960","article-title":"Body mass index in long-term adult survivors of childhood cancer: a report of the Childhood Cancer Survivor Study","volume":"103","author":"Meacham","year":"2005","journal-title":"Cancer"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0290","doi-asserted-by":"crossref","first-page":"3991","DOI":"10.1200\/JCO.2011.40.0457","article-title":"Longitudinal changes in body mass and composition in survivors of childhood hematologic malignancies after allogeneic hematopoietic stem-cell transplantation","volume":"30","author":"Inaba","year":"2012","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0295","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/j.bbmt.2016.03.016","article-title":"Metabolic syndrome after hematopoietic cell transplantation: at the intersection of treatment toxicity and immune dysfunction","volume":"22","author":"Turcotte","year":"2016","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0300","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.febslet.2012.11.019","article-title":"Doxorubicin treatment inhibits PPAR\u03b3 and may induce lipotoxicity by mimicking a type 2 diabetes-like condition in rodent models","volume":"587","author":"Arunachalam","year":"2013","journal-title":"FEBS Lett"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0305","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1002\/jcsm.12104","article-title":"Doxorubicin caused severe hyperglycaemia and insulin resistance, mediated by inhibition in AMPk signalling in skeletal muscle","volume":"7","author":"de Lima Junior","year":"2016","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0310","doi-asserted-by":"crossref","first-page":"37731","DOI":"10.1074\/jbc.R100034200","article-title":"PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth","volume":"276","author":"Rosen","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0315","doi-asserted-by":"crossref","first-page":"e0148049","DOI":"10.1371\/journal.pone.0148049","article-title":"Chemotherapy agents alter plasma lipids in breast cancer patients and show differential effects on lipid metabolism genes in liver cells","volume":"11","author":"Sharma","year":"2016","journal-title":"PLoS ONE"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0320","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1001\/archinternmed.2009.209","article-title":"Diabetes mellitus in long-term survivors of childhood cancer. Increased risk associated with radiation therapy: a report for the Childhood Cancer Survivor Study","volume":"169","author":"Meacham","year":"2009","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0325","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/S1470-2045(12)70323-6","article-title":"Radiation dose to the pancreas and risk of diabetes mellitus in childhood cancer survivors: a retrospective cohort study","volume":"13","author":"de Vathaire","year":"2012","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.bbmt.2016.12.623_bib0330","doi-asserted-by":"crossref","first-page":"2036","DOI":"10.1002\/cncr.29300","article-title":"Validity of anthropometric measurements for characterizing obesity among adult survivors of childhood cancer: a report from the St. Jude Lifetime Cohort Study","volume":"121","author":"Karlage","year":"2015","journal-title":"Cancer"}],"container-title":["Biology of Blood and Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S108387911631182X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S108387911631182X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T14:58:44Z","timestamp":1761058724000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S108387911631182X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":64,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["S108387911631182X"],"URL":"https:\/\/doi.org\/10.1016\/j.bbmt.2016.12.623","relation":{},"ISSN":["1083-8791"],"issn-type":[{"value":"1083-8791","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cardiovascular Risk Factors in Survivors of Childhood Hematopoietic Cell Transplantation Treated with Total Body Irradiation: A Longitudinal Analysis","name":"articletitle","label":"Article Title"},{"value":"Biology of Blood and Marrow Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbmt.2016.12.623","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 American Society for Blood and Marrow Transplantation.","name":"copyright","label":"Copyright"}]}}