{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T22:07:35Z","timestamp":1794002855358,"version":"4.8.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["bbmt.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biology of Blood and Marrow Transplantation"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.bbmt.2017.12.782","type":"journal-article","created":{"date-parts":[[2017,12,19]],"date-time":"2017-12-19T13:31:58Z","timestamp":1513690318000},"page":"772-778","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":74,"title":["Risk Factors, Treatment, and Immune Dysregulation in Autoimmune Cytopenia after Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients"],"prefix":"10.1016","volume":"24","author":[{"given":"Matthijs D.","family":"Kruizinga","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maarten J.D.","family":"van Tol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Bekker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja","family":"Netelenbos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frans J.","family":"Smiers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorine","family":"Bresters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja M.","family":"Jansen-Hoogendijk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monique M.","family":"van Ostaijen-ten Dam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wouter J.W.","family":"Kollen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaap J.","family":"Zwaginga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arjan C.","family":"Lankester","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robbert G.M.","family":"Bredius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbmt.2017.12.782_bib0010","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.bbmt.2013.11.014","article-title":"Autoimmune hematological diseases after allogeneic hematopoietic stem cell transplantation in children: an Italian multicenter experience","volume":"20","author":"Faraci","year":"2014","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0015","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1111\/bjh.13866","article-title":"How I manage Evans syndrome and AIHA cases in children","volume":"172","author":"Miano","year":"2016","journal-title":"Br J Haematol"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0020","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/j.1365-2141.2004.05138.x","article-title":"Autoimmune haemolytic anaemia complicating haematopoietic cell transplantation in paediatric patients: high incidence and significant mortality in unrelated donor transplants for non-malignant diseases","volume":"127","author":"O'Brien","year":"2004","journal-title":"Br J Haematol"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0025","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1182\/blood-2012-07-445965","article-title":"New autoimmune diseases after cord blood transplantation: a retrospective study of EUROCORD and the autoimmune disease working party of the European Group for Blood and Marrow Transplantation","volume":"121","author":"Daikeler","year":"2013","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0030","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1097\/00043426-200405000-00011","article-title":"Successful treatment of refractory autoimmune hemolytic anemia with monthly rituximab following nonmyeloablative stem cell transplantation for sickle cell disease","volume":"26","author":"Raj","year":"2004","journal-title":"J Pediatr Hematol Oncol"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0035","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1016\/j.bbmt.2014.06.032","article-title":"Bortezomib for refractory autoimmunity in pediatrics","volume":"20","author":"Khandelwal","year":"2014","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0040","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/trf.12815","article-title":"Successful treatment of severe immune hemolytic anemia after allogeneic stem cell transplantation with bortezomib: report of a case and review of literature","volume":"55","author":"Hosoba","year":"2015","journal-title":"Transfusion"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0045","doi-asserted-by":"crossref","first-page":"e5396","DOI":"10.1097\/MD.0000000000005396","article-title":"Risk factor analysis of autoimmune hemolytic anemia after allogeneic hematopoietic stem cell transplantation in children","volume":"95","author":"Chang","year":"2016","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0050","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1038\/sj.bmt.1701437","article-title":"Autoimmune diseases and autoimmunity post-bone marrow transplantation","volume":"22","author":"Sherer","year":"1998","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0055","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1159\/000439002","article-title":"New insights in the pathogenesis of autoimmune hemolytic anemia","volume":"42","author":"Barcellini","year":"2015","journal-title":"Transfus Med Hemother"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0060","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S1081-1206(10)62426-X","article-title":"T-cell subsets (Th1 versus Th2)","volume":"85","author":"Romagnani","year":"2000","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0065","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1111\/petr.12455","article-title":"The incidence of autoimmune hemolytic anemia in pediatric hematopoietic stem cell recipients post-first and post-second hematopoietic stem cell transplant","volume":"19","author":"Ahmed","year":"2015","journal-title":"Pediatr Transplant"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0070","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1046\/j.1365-2141.1996.7592380.x","article-title":"CMV infection after allogeneic bone marrow transplantation is associated with the occurrence of various autoantibodies and monoclonal gammopathies","volume":"95","author":"Hebart","year":"1996","journal-title":"Br J Haematol"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0075","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1002\/jmv.2111","article-title":"Autoantibody appearance in cytomegalovirus-infected liver transplant recipients: correlation with antigenemia","volume":"66","author":"Varani","year":"2002","journal-title":"J Med Virol"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0080","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.bbmt.2014.01.018","article-title":"Early cytomegalovirus reactivation leaves a specific and dynamic imprint on the reconstituting T cell compartment long-term after hematopoietic stem cell transplantation","volume":"20","author":"Lugthart","year":"2014","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0085","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1007\/s12185-010-0597-6","article-title":"Immune reconstitution and cytomegalovirus infection after allogeneic stem cell transplantation: the important impact of in vivo T cell depletion","volume":"91","author":"Schmidt-Hieber","year":"2010","journal-title":"Int J Hematol"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0090","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.bbmt.2014.11.674","article-title":"Impact of serotherapy on immune reconstitution and survival outcomes after stem cell transplantations in children: thymoglobulin versus alemtuzumab","volume":"21","author":"Willemsen","year":"2015","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0095","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1517\/14712598.2011.592824","article-title":"Alemtuzumab in allogeneic hematopoetic stem cell transplantation","volume":"11","author":"Poire","year":"2011","journal-title":"Expert Opin Biol Ther"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0100","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1038\/sj.bmt.1705641","article-title":"Autoimmune hemolytic anemia following allogeneic hematopoietic stem cell transplantation in adult patients","volume":"39","author":"Sanz","year":"2007","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0105","doi-asserted-by":"crossref","first-page":"e105706","DOI":"10.1371\/journal.pone.0105706","article-title":"Complete suppression of the gut microbiome prevents acute graft-versus-host disease following allogeneic bone marrow transplantation","volume":"9","author":"Vossen","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0110","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.semarthrit.2003.11.002","article-title":"Th1\/Th2 cytokines in patients with systemic lupus erythematosus: is tumor necrosis factor alpha protective?","volume":"33","author":"Gomez","year":"2004","journal-title":"Semin Arthritis Rheum"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0115","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/1471-2377-12-95","article-title":"TH1\/TH2 Cytokine profile in relapsing-remitting multiple sclerosis patients treated with Glatiramer acetate or Natalizumab","volume":"12","author":"Oreja-Guevara","year":"2012","journal-title":"BMC Neurol"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0120","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1006\/clim.2001.5178","article-title":"Impaired T cell function in RANTES-deficient mice","volume":"102","author":"Makino","year":"2002","journal-title":"Clin Immunol"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0125","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.vaccine.2004.06.024","article-title":"Differential polarization of immune responses by co-administration of antigens with chemokines","volume":"23","author":"Frauenschuh","year":"2004","journal-title":"Vaccine"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0130","doi-asserted-by":"crossref","first-page":"3457","DOI":"10.1182\/blood.V126.23.3457.3457","article-title":"Bortezomib yields high response rates in antibody-mediated autoimmune hematological diseases refractory to conventional immunosuppression","volume":"126","author":"Ratnasingam","year":"2015","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0135","doi-asserted-by":"crossref","first-page":"2324","DOI":"10.1002\/pbc.25172","article-title":"Bortezomib for effective treatment of a child with refractory autoimmune hemolytic anemia post allogeneic Hematopoietic Stem Cell Transplant","volume":"61","author":"Mehta","year":"2014","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.bbmt.2017.12.782_bib0140","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1182\/blood-2015-07-657981","article-title":"Sirolimus is effective in relapsed\/refractory autoimmune cytopenias: results of a prospective multi-institutional trial","volume":"127","author":"Bride","year":"2016","journal-title":"Blood"}],"container-title":["Biology of Blood and Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083879117317081?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083879117317081?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:01:13Z","timestamp":1761058873000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1083879117317081"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["S1083879117317081"],"URL":"https:\/\/doi.org\/10.1016\/j.bbmt.2017.12.782","relation":{},"ISSN":["1083-8791"],"issn-type":[{"value":"1083-8791","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Risk Factors, Treatment, and Immune Dysregulation in Autoimmune Cytopenia after Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients","name":"articletitle","label":"Article Title"},{"value":"Biology of Blood and Marrow Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbmt.2017.12.782","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 American Society for Blood and Marrow Transplantation.","name":"copyright","label":"Copyright"}]}}