{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T04:05:44Z","timestamp":1774497944819,"version":"3.50.1"},"reference-count":42,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["bbmt.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biology of Blood and Marrow Transplantation"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.bbmt.2019.07.010","type":"journal-article","created":{"date-parts":[[2019,7,12]],"date-time":"2019-07-12T19:21:19Z","timestamp":1562959279000},"page":"2217-2221","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["Successful Outcome in Patients with Fanconi Anemia Undergoing T Cell-Replete Mismatched Related Donor Hematopoietic Cell Transplantation Using Reduced-Dose Cyclophosphamide Post-Transplantation"],"prefix":"10.1016","volume":"25","author":[{"given":"Mouhab","family":"Ayas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9581-7993","authenticated-orcid":false,"given":"Khawar","family":"Siddiqui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah","family":"Al-Jefri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Al-Ahmari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim","family":"Ghemlas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hawazen","family":"Al-Saedi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Awatif","family":"Alanazi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafat","family":"Jafri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamad F.","family":"Ayas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amal","family":"Al-Seraihi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbmt.2019.07.010_bib0001","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.hemonc.2017.05.014","article-title":"Hematopoietic cell transplantation in Fanconi anemia and dyskeratosis congenita: a minireview","volume":"10","author":"Ayas","year":"2017","journal-title":"Hematol Oncol Stem Cell Ther"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0002","doi-asserted-by":"crossref","first-page":"3676","DOI":"10.1182\/blood-2015-04-639476","article-title":"Improving survival for Fanconi anemia patients","volume":"125","author":"Gluckman","year":"2015","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0003","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.3324\/haematol.2010.025619","article-title":"Inherited bone marrow failure syndromes","volume":"95","author":"Dokal","year":"2010","journal-title":"Haematologica"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0004","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.beha.2014.10.002","article-title":"Fanconi anemia and the development of leukemia","volume":"27","author":"Alter","year":"2014","journal-title":"Best Pract Res Clin Haematol"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0005","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.hoc.2018.04.002","article-title":"Myelodysplastic syndrome, acute myeloid leukemia, and cancer surveillance in Fanconi anemia","volume":"32","author":"Savage","year":"2018","journal-title":"Hematol Oncol Clin North Am"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0006","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.critrevonc.2018.02.013","article-title":"Oral cancer in Fanconi anemia: review of 121 cases","volume":"125","author":"Furquim","year":"2018","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0007","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/nrc.2017.116","article-title":"Fanconi anaemia and cancer: an intricate relationship","volume":"18","author":"Nalepa","year":"2018","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0008","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1038\/sj.bmt.1702754","article-title":"Bone marrow transplantation from matched siblings in patients with Fanconi anemia utilizing low-dose cyclophosphamide, thoracoabdominal radiation and antithymocyte globulin","volume":"27","author":"Ayas","year":"2001","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0009","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1111\/j.1365-2141.2006.06460.x","article-title":"Matched sibling donor haematopoietic stem cell transplantation in Fanconi anaemia: an update of the Cincinnati Children's experience","volume":"136","author":"Farzin","year":"2007","journal-title":"Br J Haematol"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0010","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.bbmt.2011.08.015","article-title":"The Saudi experience in fludarabine-based conditioning regimens in patients with Fanconi anemia undergoing stem cell transplantation: excellent outcome in recipients of matched related stem cells but not in recipients of unrelated cord blood stem cells","volume":"18","author":"Ayas","year":"2012","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0011","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1016\/j.bbmt.2014.06.016","article-title":"Factors affecting the outcome of related allogeneic hematopoietic cell transplantation in patients with Fanconi anemia","volume":"20","author":"Ayas","year":"2014","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0012","doi-asserted-by":"crossref","first-page":"2256","DOI":"10.1182\/blood-2006-07-036657","article-title":"Unrelated donor bone marrow transplantation for the treatment of Fanconi anemia","volume":"109","author":"Wagner","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0013","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.bbmt.2007.05.015","article-title":"Results of unrelated cord blood transplant in Fanconi anemia patients: risk factor analysis for engraftment and survival","volume":"13","author":"Gluckman","year":"2007","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0014","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1038\/bmt.2009.350","article-title":"Unrelated cord blood transplantation in pediatric patients: a report from Saudi Arabia","volume":"45","author":"Ayas","year":"2010","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0015","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/bmt.2015.20","article-title":"Haploidentical BMT and post-transplant Cy for severe aplastic anemia: a multicenter retrospective study","volume":"50","author":"Esteves","year":"2015","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0016","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1016\/j.bbmt.2018.03.031","article-title":"Haploidentical peripheral blood stem cell transplantation demonstrates stable engraftment in adults with sickle cell disease","volume":"24","author":"Saraf","year":"2018","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0017","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/j.bbmt.2016.02.001","article-title":"Alternative-donor hematopoietic stem cell transplantation with post-transplantation cyclophosphamide for nonmalignant disorders","volume":"22","author":"Klein","year":"2016","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0018","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1097\/MOH.0000000000000412","article-title":"Have haploidentical transplants replaced umbilical cord transplants for acute leukemias?","volume":"25","author":"Liu","year":"2018","journal-title":"Curr Opin Hematol"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0019","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1002\/ajh.23995","article-title":"An overview of conditioning regimens for haploidentical stem cell transplantation with post-transplantation cyclophosphamide","volume":"90","author":"Shabbir-Moosajee","year":"2015","journal-title":"Am J Hematol"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0020","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1111\/j.1365-2141.1980.tb07179.x","article-title":"In vitro effect of cyclophosphamide metabolites on chromosomes of Fanconi anaemia patients","volume":"45","author":"Berger","year":"1980","journal-title":"Br J Haematol"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0021","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/j.1365-2141.1983.tb02117.x","article-title":"Radiosensitivity in Fanconi anaemia: application to the conditioning regimen for bone marrow transplantation","volume":"54","author":"Gluckman","year":"1983","journal-title":"Br J Haematol"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0022","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1016\/j.bbmt.2007.08.004","article-title":"HLA-matched related donor hematopoietic cell transplantation in 43 patients with Fanconi anemia conditioned with 60 mg\/kg of cyclophosphamide","volume":"13","author":"Bonfim","year":"2007","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0023","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/sj.bmt.1704787","article-title":"Stem cell transplantation for patients with Fanconi anemia with low-dose cyclophosphamide and antithymocyte globulins without the use of radiation therapy","volume":"35","author":"Ayas","year":"2005","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0024","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/sj.bmt.1704785","article-title":"Fludarabine-based conditioning for allogeneic stem cell transplantation for multiply transfused patients with Fanconi's anemia","volume":"35","author":"George","year":"2005","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0025","doi-asserted-by":"crossref","first-page":"3798","DOI":"10.1182\/blood-2015-02-626002","article-title":"Alternative donor hematopoietic cell transplantation for Fanconi anemia","volume":"125","author":"MacMillan","year":"2015","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0026","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1532\/IJH97.04004","article-title":"Unmanipulated HLA-haploidentical bone marrow transplantation for the treatment of fatal, nonmalignant diseases in children and adolescents","volume":"80","author":"Yabe","year":"2004","journal-title":"Int J Hematol"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0027","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1111\/j.1365-2141.2006.06300.x","article-title":"Current status of haploidentical stem cell transplantation","volume":"135","author":"Dey","year":"2006","journal-title":"Br J Haematol"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0028","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1002\/pbc.22584","article-title":"Haploidentical stem cell transplantation as a salvage therapy for cord blood engraftment failure in a patient with Fanconi anemia","volume":"55","author":"Rihani","year":"2010","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0029","first-page":"1153","article-title":"Stem cell transplantation for the treatment of Fanconi anaemia using a fludarabine-based cytoreductive regimen and T-cell-depleted related HLA-mismatched peripheral blood stem cell grafts","volume":"111","author":"Boulad","year":"2000","journal-title":"Br J Haematol"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0030","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1038\/bmt.2011.148","article-title":"Feasibility and outcome of haploidentical SCT in pediatric high-risk hematologic malignancies and Fanconi anemia in Uruguay","volume":"47","author":"Dufort","year":"2012","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0031","doi-asserted-by":"crossref","first-page":"568","DOI":"10.3109\/08880018.2012.708708","article-title":"Cyclophosphamide-based in vivo T-cell depletion for HLA-haploidentical transplantation in Fanconi anemia","volume":"29","author":"Thakar","year":"2012","journal-title":"Pediatr Hematol Oncol"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0032","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1038\/sj.bmt.1703903","article-title":"Successful T-cell-depleted, related haploidentical peripheral blood stem cell transplantation in a patient with Fanconi anaemia using a fludarabine-based preparative regimen without radiation","volume":"31","author":"Rossi","year":"2003","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0033","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.bbmt.2014.01.015","article-title":"HLA-haploidentical T cell-depleted allogeneic hematopoietic stem cell transplantation in children with Fanconi anemia","volume":"20","author":"Zecca","year":"2014","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0034","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.1182\/blood-2016-09-743112","article-title":"Radiation-free, alternative-donor HCT for Fanconi anemia patients: results from a prospective multi-institutional study","volume":"129","author":"Mehta","year":"2017","journal-title":"Blood"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0035","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1111\/j.1365-2141.2007.06975.x","article-title":"Fludarabine-based cytoreductive regimen and T-cell-depleted grafts from alternative donors for the treatment of high-risk patients with Fanconi anaemia","volume":"140","author":"Chaudhury","year":"2008","journal-title":"Br J Haematol"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0036","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1038\/sj.bmt.1702701","article-title":"Successful haploidentical bone marrow transplantation in Fanconi anemia","volume":"26","author":"Elhasid","year":"2000","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0037","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.bbmt.2016.12.628","article-title":"Alternative donor transplantation with high-dose post-transplantation cyclophosphamide for refractory severe aplastic anemia","volume":"23","author":"DeZern","year":"2017","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0038","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.bbmt.2012.08.014","article-title":"Unmanipulated haploidentical bone marrow transplantation and posttransplantation cyclophosphamide for hematologic malignancies after myeloablative conditioning","volume":"19","author":"Raiola","year":"2013","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0039","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1038\/bmt.2016.301","article-title":"Dose-adapted post-transplant cyclophosphamide for HLA-haploidentical transplantation in Fanconi anemia","volume":"52","author":"Thakar","year":"2017","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0040","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.bbmt.2016.11.006","article-title":"Haploidentical bone marrow transplantation with post-transplant cyclophosphamide for children and adolescents with Fanconi anemia","volume":"23","author":"Bonfim","year":"2017","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0041","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1182\/bloodadvances.2016001552","article-title":"ATG in allogeneic stem cell transplantation: standard of care in 2017? Counterpoint","volume":"1","author":"Kekre","year":"2017","journal-title":"Blood Adv"},{"key":"10.1016\/j.bbmt.2019.07.010_bib0042","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1111\/tid.12455","article-title":"Incidence and risk factors for hemorrhagic cystitis in unmanipulated haploidentical transplant recipients","volume":"17","author":"Ruggeri","year":"2015","journal-title":"Transpl Infect Dis"}],"container-title":["Biology of Blood and Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083879119304422?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083879119304422?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:06:13Z","timestamp":1761059173000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1083879119304422"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":42,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["S1083879119304422"],"URL":"https:\/\/doi.org\/10.1016\/j.bbmt.2019.07.010","relation":{},"ISSN":["1083-8791"],"issn-type":[{"value":"1083-8791","type":"print"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Successful Outcome in Patients with Fanconi Anemia Undergoing T Cell-Replete Mismatched Related Donor Hematopoietic Cell Transplantation Using Reduced-Dose Cyclophosphamide Post-Transplantation","name":"articletitle","label":"Article Title"},{"value":"Biology of Blood and Marrow Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbmt.2019.07.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 American Society for Transplantation and Cellular Therapy. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}