{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T02:54:21Z","timestamp":1789008861178,"version":"build-2803163510"},"reference-count":21,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["bbmt.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biology of Blood and Marrow Transplantation"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.bbmt.2020.05.023","type":"journal-article","created":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T11:46:34Z","timestamp":1591184794000},"page":"e222-e226","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["A Case Series of Post-Transplantation Cyclophosphamide in Unrelated Donor Hematopoietic Cell Transplantation for Aplastic Anemia"],"prefix":"10.1016","volume":"26","author":[{"given":"Leonardo Javier","family":"Arcuri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samir Kanaan","family":"Nabhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gisele","family":"Loth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elias Hallack","family":"Atta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Nichele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato de Castro","family":"Araujo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmem","family":"Bonfim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbmt.2020.05.023_bib0001","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1182\/blood-2006-03-005041","article-title":"Optimization of conditioning for marrow transplantation from unrelated donors for patients with aplastic anemia after failure of immunosuppressive therapy","volume":"108","author":"Deeg","year":"2006","journal-title":"Blood."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0002","doi-asserted-by":"crossref","first-page":"e367","DOI":"10.1016\/S2352-3026(15)00147-7","article-title":"Cyclophosphamide conditioning in patients with severe aplastic anaemia given unrelated marrow transplantation: a phase 1-2 dose de-escalation study","volume":"2","author":"Anderlini","year":"2015","journal-title":"Lancet Haematol."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0003","doi-asserted-by":"crossref","first-page":"976","DOI":"10.3324\/haematol.2009.018267","article-title":"Fludarabine, cyclophosphamide, antithymocyte globulin, with or without low dose total body irradiation, for alternative donor transplants, in acquired severe aplastic anemia: a retrospective study from the EBMT-SAA Working Party","volume":"95","author":"Bacigalupo","year":"2010","journal-title":"Haematologica."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0004","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1182\/blood-2016-08-693481","article-title":"How I treat acquired aplastic anemia","volume":"129","author":"Bacigalupo","year":"2017","journal-title":"Blood."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0005","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1097\/MOH.0000000000000382","article-title":"Hematopoietic cell transplantation for aplastic anemia","volume":"24","author":"Kumar","year":"2017","journal-title":"Curr Opin Hematol."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0006","doi-asserted-by":"crossref","first-page":"e13552","DOI":"10.1111\/petr.13552","volume":"23","author":"Darrigo","year":"2019","journal-title":"Pediatr Transplant."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0007","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1016\/j.bbmt.2012.07.004","article-title":"Different outcomes between cyclophosphamide plus horse or rabbit antithymocyte globulin for HLA-identical sibling bone marrow transplant in severe aplastic anemia","volume":"18","author":"Atta","year":"2012","journal-title":"Biol Blood Marrow Transplant."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0008","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/j.bbmt.2016.01.012","article-title":"Comparing outcomes with bone marrow or peripheral blood stem cells as graft source for matched sibling transplants in severe aplastic anemia across different economic regions","volume":"22","author":"Kumar","year":"2016","journal-title":"Biol Blood Marrow Transplant."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0009","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1590\/S0037-86822010000400004","article-title":"Seroprevalence of cytomegalovirus antibodies in blood donors in southern Brazil","volume":"43","author":"Souza","year":"2010","journal-title":"Rev Soc Bras Med Trop."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0010","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.jiph.2018.07.001","article-title":"Seroprevalence of Toxoplasma gondii, cytomegalovirus and Epstein Barr virus in 578 tissue donors in Brazil","volume":"12","author":"Tuon","year":"2019","journal-title":"J Infect Public Health."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0011","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/bmt.2015.20","article-title":"Haploidentical BMT and post-transplant Cy for severe aplastic anemia: a multicenter retrospective study","volume":"50","author":"Esteves","year":"2015","journal-title":"Bone Marrow Transplant."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0012","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.bbmt.2008.03.005","article-title":"HLA-haploidentical bone marrow transplantation for hematologic malignancies using nonmyeloablative conditioning and high-dose, posttransplantation cyclophosphamide","volume":"14","author":"Luznik","year":"2008","journal-title":"Biol Blood Marrow Transplant."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0013","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.bbmt.2009.01.017","article-title":"Rapid transport and infusion of hematopoietic cells is associated with improved outcome after myeloablative therapy and unrelated donor transplant","volume":"15","author":"Lazarus","year":"2009","journal-title":"Biol Blood Marrow Transplant."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.exphem.2015.07.006","article-title":"HLA haploidentical peripheral blood stem cell transplantation using reduced dose of posttransplantation cyclophosphamide for poor-prognosis or refractory leukemia and myelodysplastic syndrome","volume":"43","author":"Nakamae","year":"2015","journal-title":"Exp Hematol."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0015","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1007\/s00277-019-03673-3","article-title":"Reduced dose of post-transplantation cyclophosphamide compared to ATG for graft-versus-host disease prophylaxis in recipients of mismatched unrelated donor hematopoietic cell transplantation: a single-center study","volume":"98","author":"Soltermann","year":"2019","journal-title":"Ann Hematol."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0016","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/j.bbmt.2018.01.031","article-title":"A modified post-transplant cyclophosphamide regimen, for unmanipulated haploidentical marrow transplantation, in acute myeloid leukemia: a multicenter study","volume":"24","author":"Chiusolo","year":"2018","journal-title":"Biol Blood Marrow Transplant."},{"issue":"suppl 2","key":"10.1016\/j.bbmt.2020.05.023_bib0017","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/s41409-019-0594-1","article-title":"Graft versus host disease in unmanipulated haploidentical marrow transplantation with a modified post-transplant cyclophosphamide (PT-CY) regimen: an update on 425 patients","volume":"54","author":"Bacigalupo","year":"2019","journal-title":"Bone Marrow Transplant."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0018","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1016\/j.bbmt.2013.07.013","article-title":"Absence of post-transplantation lymphoproliferative disorder after allogeneic blood or marrow transplantation using post-transplantation cyclophosphamide as graft-versus-host disease prophylaxis","volume":"19","author":"Kanakry","year":"2013","journal-title":"Biol Blood Marrow Transplant."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0019","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1080\/10428194.2018.1543877","article-title":"Prophylactic rituximab prevents EBV PTLD in haplo-cord transplant recipients at high risk","volume":"60","author":"Van Besien","year":"2019","journal-title":"Leuk Lymphoma."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0020","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1038\/s41409-019-0773-0","article-title":"Haploidentical transplantation and posttransplant cyclophosphamide for treating aplastic anemia patients: a report from the EBMT Severe Aplastic Anemia Working Party","volume":"55","author":"Prata","year":"2020","journal-title":"Bone Marrow Transplant."},{"key":"10.1016\/j.bbmt.2020.05.023_bib0021","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1182\/bloodadvances.2020001729","article-title":"Haploidentical BMT for severe aplastic anemia with intensive GVHD prophylaxis including posttransplant cyclophosphamide","volume":"4","author":"DeZern","year":"2020","journal-title":"Blood Adv."}],"container-title":["Biology of Blood and Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S108387912030344X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S108387912030344X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:12:07Z","timestamp":1761059527000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S108387912030344X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":21,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["S108387912030344X"],"URL":"https:\/\/doi.org\/10.1016\/j.bbmt.2020.05.023","relation":{},"ISSN":["1083-8791"],"issn-type":[{"value":"1083-8791","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Case Series of Post-Transplantation Cyclophosphamide in Unrelated Donor Hematopoietic Cell Transplantation for Aplastic Anemia","name":"articletitle","label":"Article Title"},{"value":"Biology of Blood and Marrow Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbmt.2020.05.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 American Society for Transplantation and Cellular Therapy. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}