{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T09:33:34Z","timestamp":1789205614967,"version":"build-2803163510"},"reference-count":78,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Behavioural Brain Research"],"published-print":{"date-parts":[[2011,10]]},"DOI":"10.1016\/j.bbr.2011.05.008","type":"journal-article","created":{"date-parts":[[2011,5,22]],"date-time":"2011-05-22T19:13:54Z","timestamp":1306091634000},"page":"223-232","source":"Crossref","is-referenced-by-count":23,"title":["Sex-specific neuroendocrine and behavioral phenotypes in hypomorphic Type II Neuregulin 1 rats"],"prefix":"10.1016","volume":"224","author":[{"given":"Sara B.","family":"Taylor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie A.","family":"Markham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam R.","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brooke Z.","family":"Kanaskie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James I.","family":"Koenig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbr.2011.05.008_bib0005","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1038\/nrn2392","article-title":"Neuregulin 1 in neural development, synaptic plasticity and schizophrenia","volume":"9","author":"Mei","year":"2008","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.bbr.2011.05.008_bib0010","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0014-4827(02)00102-7","article-title":"Neuregulins: functions, forms, and signaling strategies","volume":"284","author":"Falls","year":"2003","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.bbr.2011.05.008_bib0015","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.biopsych.2005.11.002","article-title":"Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology","volume":"60","author":"Harrison","year":"2006","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.bbr.2011.05.008_bib0020","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1523\/JNEUROSCI.23-01-00230.2003","article-title":"Normal female sexual development requires neuregulin-erbB receptor signaling in hypothalamic astrocytes","volume":"23","author":"Prevot","year":"2003","journal-title":"J Neurosci"},{"key":"10.1016\/j.bbr.2011.05.008_bib0025","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.neuroscience.2004.04.026","article-title":"Neuregulin-1 (NRG-1) mRNA and protein in the adult human brain","volume":"127","author":"Law","year":"2004","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbr.2011.05.008_bib0030","article-title":"Disruption of the neuregulin 1 gene in the rat alters HPA axis activity and behavioral responses to environmental stimuli","author":"Taylor","year":"2010","journal-title":"Physiol Behav"},{"key":"10.1016\/j.bbr.2011.05.008_bib0035","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1086\/342734","article-title":"Neuregulin 1 and susceptibility to schizophrenia","volume":"71","author":"Stefansson","year":"2002","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.bbr.2011.05.008_bib0040","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1086\/345442","article-title":"Association of neuregulin 1 with schizophrenia confirmed in a Scottish population","volume":"72","author":"Stefansson","year":"2003","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.bbr.2011.05.008_bib0045","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1097\/YPG.0b013e32832a4f69","article-title":"An association study of the neuregulin 1 gene, bipolar affective disorder and psychosis","volume":"19","author":"Prata","year":"2009","journal-title":"Psychiatr Genet"},{"key":"10.1016\/j.bbr.2011.05.008_bib0050","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1210\/er.19.3.269","article-title":"Brain corticosteroid receptor balance in health and disease","volume":"19","author":"de Kloet","year":"1998","journal-title":"Endocr Rev"},{"key":"10.1016\/j.bbr.2011.05.008_bib0055","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.1523\/JNEUROSCI.2173-05.2006","article-title":"Forebrain glucocorticoid receptors modulate anxiety-associated locomotor activation and adrenal responsiveness","volume":"26","author":"Boyle","year":"2006","journal-title":"J Neurosci"},{"key":"10.1016\/j.bbr.2011.05.008_bib0060","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.brainres.2009.03.061","article-title":"Defining brain region-specific glucocorticoid action during stress by conditional gene disruption in mice","volume":"1293","author":"Kolber","year":"2009","journal-title":"Brain Res"},{"key":"10.1016\/j.bbr.2011.05.008_bib0065","doi-asserted-by":"crossref","first-page":"12004","DOI":"10.1073\/pnas.0803216105","article-title":"Central amygdala glucocorticoid receptor action promotes fear-associated CRH activation and conditioning","volume":"105","author":"Kolber","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.bbr.2011.05.008_bib0070","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1146\/annurev.clinpsy.4.022007.141248","article-title":"Stress and the hypothalamic pituitary adrenal axis in the developmental course of schizophrenia","volume":"4","author":"Walker","year":"2008","journal-title":"Annu Rev Clin Psychol"},{"key":"10.1016\/j.bbr.2011.05.008_bib0075","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1176\/ajp.156.6.837","article-title":"Causal relationship between stressful life events and the onset of major depression","volume":"156","author":"Kendler","year":"1999","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.bbr.2011.05.008_bib0080","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1521\/jscp.2007.26.4.460","article-title":"Childhood stressful life events and bipolar spectrum disorders","volume":"26","author":"Grandin","year":"2007","journal-title":"J Soc Clin Psychol"},{"key":"10.1016\/j.bbr.2011.05.008_bib0085","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0893-133X(01)00396-7","article-title":"Glucocorticoid hormones and early brain development in schizophrenia","volume":"27","author":"Koenig","year":"2002","journal-title":"Neuropsychopharmacology"},{"issue":"Suppl 1","key":"10.1016\/j.bbr.2011.05.008_bib0090","doi-asserted-by":"crossref","first-page":"S87","DOI":"10.1016\/S0306-4530(97)00020-6","article-title":"Behavioral and neuroendocrine responses controlled by the concerted action of central mineralocorticoid (MRS) and glucocorticoid receptors (GRS)","volume":"22","author":"Oitzl","year":"1997","journal-title":"Psychoneuroendocrinology"},{"issue":"24","key":"10.1016\/j.bbr.2011.05.008_bib0095","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1038\/sj.mp.4001139","article-title":"Regional specificity of brain glucocorticoid receptor mRNA alterations in subjects with schizophrenia and mood disorders","volume":"7","author":"Webster","year":"2002","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.bbr.2011.05.008_bib0100","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.schres.2007.10.013","article-title":"Increased levels of serotonin 2A receptors and serotonin transporter in the CNS of neuregulin 1 hypomorphic\/mutant mice","volume":"99","author":"Dean","year":"2008","journal-title":"Schizophr Res"},{"key":"10.1016\/j.bbr.2011.05.008_bib0105","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.neuroscience.2007.03.051","article-title":"Phenotypic characterization of spatial cognition and social behavior in mice with \u2018knockout\u2019 of the schizophrenia risk gene neuregulin 1","volume":"147","author":"O\u2019Tuathaigh","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbr.2011.05.008_bib0110","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0166-4328(99)00175-8","article-title":"Heregulin, but not ErbB2 or ErbB3, heterozygous mutant mice exhibit hyperactivity in multiple behavioral tasks","volume":"109","author":"Gerlai","year":"2000","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.bbr.2011.05.008_bib0115","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1097\/00001756-200502280-00014","article-title":"Neuregulin-1 immunoglobulin-like domain mutant mice: clozapine sensitivity and impaired latent inhibition","volume":"16","author":"Rimer","year":"2005","journal-title":"Neuroreport"},{"key":"10.1016\/j.bbr.2011.05.008_bib0120","doi-asserted-by":"crossref","first-page":"24343","DOI":"10.1074\/jbc.M702953200","article-title":"Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia","volume":"282","author":"Tan","year":"2007","journal-title":"J Biol Chem"},{"key":"10.1016\/j.bbr.2011.05.008_bib0125","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1111\/j.1471-4159.2010.06677.x","article-title":"Molecular and cellular characterization of Neuregulin-1 type IV isoforms","volume":"113","author":"Shamir","year":"2010","journal-title":"J Neurochem"},{"key":"10.1016\/j.bbr.2011.05.008_bib0130","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1097\/01.wnr.0000192738.31029.0a","article-title":"Sexually dimorphic changes in the exploratory and habituation profiles of heterozygous neuregulin-1 knockout mice","volume":"17","author":"O\u2019Tuathaigh","year":"2006","journal-title":"Neuroreport"},{"key":"10.1016\/j.bbr.2011.05.008_bib0135","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.pnpbp.2007.09.018","article-title":"Disruption to social dyadic interactions but not emotional\/anxiety-related behaviour in mice with heterozygous \u2018knockout\u2019 of the schizophrenia risk gene neuregulin-1","volume":"32","author":"O\u2019Tuathaigh","year":"2008","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.bbr.2011.05.008_bib0140","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1037\/0735-7044.122.4.748","article-title":"Behavioral profile of a heterozygous mutant mouse model for EGF-like domain neuregulin 1","volume":"122","author":"Duffy","year":"2008","journal-title":"Behav Neurosci"},{"key":"10.1016\/j.bbr.2011.05.008_bib0145","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1097\/WNR.0b013e328330f6e7","article-title":"Behavioural characterization of neuregulin 1 type I overexpressing transgenic mice","volume":"20","author":"Deakin","year":"2009","journal-title":"Neuroreport"},{"key":"10.1016\/j.bbr.2011.05.008_bib0150","doi-asserted-by":"crossref","first-page":"6872","DOI":"10.1523\/JNEUROSCI.1815-08.2008","article-title":"Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components","volume":"28","author":"Chen","year":"2008","journal-title":"J Neurosci"},{"key":"10.1016\/j.bbr.2011.05.008_bib0155","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1210\/endo-98-3-630","article-title":"The onset of puberty in the female rat: changes in plasma prolactin, gonadotropins, luteinizing hormone-releasing hormone (LHRH), and hypothalamic LHRH content","volume":"98","author":"Ojeda","year":"1976","journal-title":"Endocrinology"},{"key":"10.1016\/j.bbr.2011.05.008_bib0160","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1590\/S1519-69842002000400008","article-title":"Determination of the estrous cycle phases of rats: some helpful considerations","volume":"62","author":"Marcondes","year":"2002","journal-title":"Braz J Biol"},{"key":"10.1016\/j.bbr.2011.05.008_bib0165","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1080\/10520290500138422","article-title":"A quantitative method for assessing stages of the rat estrous cycle","volume":"80","author":"Hubscher","year":"2005","journal-title":"Biotech Histochem"},{"key":"10.1016\/j.bbr.2011.05.008_bib0170","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.bbr.2004.05.030","article-title":"Prenatal exposure to a repeated variable stress paradigm elicits behavioral and neuroendocrinological changes in the adult offspring: potential relevance to schizophrenia","volume":"156","author":"Koenig","year":"2005","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.bbr.2011.05.008_bib0175","series-title":"The Rat Brain in Stereotaxic Coordinates","author":"Paxinos","year":"1986"},{"key":"10.1016\/j.bbr.2011.05.008_bib0180","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1289\/ehp.10165","article-title":"Variations in phytoestrogen content between different mill dates of the same diet produces significant differences in the time of vaginal opening in CD-1 mice and F344 rats but not in CD Sprague-Dawley rats","volume":"115","author":"Thigpen","year":"2007","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.bbr.2011.05.008_bib0185","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/cne.903490306","article-title":"Expression of multiple neuregulin transcripts in postnatal rat brains","volume":"349","author":"Chen","year":"1994","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.bbr.2011.05.008_bib0190","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1749-6632.2009.04979.x","article-title":"Status of glucocorticoid alterations in post-traumatic stress disorder","volume":"1179","author":"Yehuda","year":"2009","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.bbr.2011.05.008_bib0195","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.psyneuen.2005.05.014","article-title":"Effects of a single footshock followed by situational reminders on HPA axis and behaviour in the aversive context in male and female rats","volume":"31","author":"Louvart","year":"2006","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.bbr.2011.05.008_bib0200","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/j.pnpbp.2005.08.006","article-title":"Limbic system mechanisms of stress regulation: hypothalamo-pituitary-adrenocortical axis","volume":"29","author":"Herman","year":"2005","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.bbr.2011.05.008_bib0205","doi-asserted-by":"crossref","first-page":"8836","DOI":"10.1523\/JNEUROSCI.0910-07.2007","article-title":"Overexpressing the glucocorticoid receptor in forebrain causes an aging-like neuroendocrine phenotype and mild cognitive dysfunction","volume":"27","author":"Wei","year":"2007","journal-title":"J Neurosci"},{"key":"10.1016\/j.bbr.2011.05.008_bib0210","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1023\/A:1026499604848","article-title":"Rapid non-genomic feedback effects of glucocorticoids on CRF-induced ACTH secretion in rats","volume":"17","author":"Hinz","year":"2000","journal-title":"Pharm Res"},{"key":"10.1016\/j.bbr.2011.05.008_bib0215","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.psyneuen.2010.09.007","article-title":"Pituitary glucocorticoid receptor deletion reduces vulnerability to chronic stress","volume":"36","author":"Wagner","year":"2010","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.bbr.2011.05.008_bib0220","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1080\/10253890701821081","article-title":"Hypothalamic-pituitary-adrenal axis dysregulation and behavioral analysis of mouse mutants with altered glucocorticoid or mineralocorticoid receptor function","volume":"11","author":"Kolber","year":"2008","journal-title":"Stress"},{"key":"10.1016\/j.bbr.2011.05.008_bib0225","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1046\/j.1365-2826.2003.01100.x","volume":"15","author":"Ginsberg","year":"2003","journal-title":"J Neuroendocrinol"},{"key":"10.1016\/j.bbr.2011.05.008_bib0230","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.yfrne.2005.09.001","article-title":"Glucocorticoid regulation of peptide genes in neuroendocrine CRH neurons: a complexity beyond negative feedback","volume":"26","author":"Watts","year":"2005","journal-title":"Front Neuroendocrinol"},{"key":"10.1016\/j.bbr.2011.05.008_bib0235","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1080\/10253890701794767","article-title":"Dexamethasone and stressor-magnitude regulation of stress-induced transcription of HPA axis secretagogues in the rat","volume":"11","author":"Helmreich","year":"2008","journal-title":"Stress"},{"key":"10.1016\/j.bbr.2011.05.008_bib0240","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1073\/pnas.0910302107","article-title":"Neuregulin 1 regulates pyramidal neuron activity via ErbB4 in parvalbumin-positive interneurons","volume":"107","author":"Wen","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.bbr.2011.05.008_bib0245","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1523\/JNEUROSCI.2538-10.2011","article-title":"Neuregulin 1 promotes excitatory synapse development and function in GABAergic interneurons","volume":"31","author":"Ting","year":"2010","journal-title":"J Neurosci"},{"key":"10.1016\/j.bbr.2011.05.008_bib0250","doi-asserted-by":"crossref","first-page":"4801","DOI":"10.1210\/en.141.12.4801","article-title":"Local integration of glutamate signaling in the hypothalamic paraventricular region: regulation of glucocorticoid stress responses","volume":"141","author":"Ziegler","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.bbr.2011.05.008_bib0255","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1196\/annals.1296.004","article-title":"Role of GABA and glutamate circuitry in hypothalamo-pituitary-adrenocortical stress integration","volume":"1018","author":"Herman","year":"2004","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.bbr.2011.05.008_bib0260","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1038\/sj.npp.1300926","article-title":"Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels: implications for stress-related psychiatric disorders","volume":"31","author":"Mitsukawa","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbr.2011.05.008_bib0265","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/S0022-3565(25)23831-9","article-title":"Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response","volume":"271","author":"Bakshi","year":"1994","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.bbr.2011.05.008_bib0270","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0003-3472(73)80065-X","article-title":"Tests for emotionality in rats and mice: a review","volume":"21","author":"Archer","year":"1973","journal-title":"Anim Behav"},{"key":"10.1016\/j.bbr.2011.05.008_bib0275","series-title":"Handbook of Molecular-Genetic Techniques for Brain and Behavior Research","first-page":"738","article-title":"Measuring rodent exploratory behaviour","author":"Belzung","year":"1999"},{"key":"10.1016\/j.bbr.2011.05.008_bib0280","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.pbb.2009.11.008","article-title":"Enhanced habituation and decreased anxiety by environmental enrichment and possible attenuation of these effects by chronic alpha-tocopherol (vitamin E) in aging male and female rats","volume":"94","author":"Hughes","year":"2010","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.bbr.2011.05.008_bib0285","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/j.1749-6632.1997.tb48289.x","article-title":"Roles of the amygdala and bed nucleus of the stria terminalis in fear and anxiety measured with the acoustic startle reflex. Possible relevance to PTSD","volume":"821","author":"Davis","year":"1997","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.bbr.2011.05.008_bib0290","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/S0892-0362(02)00317-3","article-title":"The effects of perinatal AZT exposure on the acoustic startle response in adult rats","volume":"24","author":"Melnick","year":"2002","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.bbr.2011.05.008_bib0295","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.physbeh.2005.02.004","article-title":"Effects of sex and estrous cycle on modulation of the acoustic startle response in mice","volume":"84","author":"Plappert","year":"2005","journal-title":"Physiol Behav"},{"key":"10.1016\/j.bbr.2011.05.008_bib0300","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.psyneuen.2007.11.005","article-title":"Endogenous neurotensin is involved in estrous cycle related alterations in prepulse inhibition of the acoustic startle reflex in female rats","volume":"33","author":"Kinkead","year":"2008","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.bbr.2011.05.008_bib0305","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/S0031-9384(98)00098-5","article-title":"Sensorimotor gating changes across the estrous cycle in female rats","volume":"64","author":"Koch","year":"1998","journal-title":"Physiol Behav"},{"key":"10.1016\/j.bbr.2011.05.008_bib0310","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S0006-8993(98)01258-X","article-title":"Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests","volume":"835","author":"Crawley","year":"1999","journal-title":"Brain Res"},{"key":"10.1016\/j.bbr.2011.05.008_bib0315","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.biopsych.2007.05.011","article-title":"Evidence of missense mutations on the neuregulin 1 gene affecting function of prepulse inhibition","volume":"63","author":"Hong","year":"2008","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.bbr.2011.05.008_bib0320","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1001\/archpsyc.1990.01810140081011","article-title":"Sensorimotor gating and schizophrenia. Human and animal model studies","volume":"47","author":"Braff","year":"1990","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.bbr.2011.05.008_bib0325","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1111\/j.1467-9280.2008.02131.x","article-title":"Modality-specific attention under imminent but not remote threat of shock: evidence from differential prepulse inhibition of startle","volume":"19","author":"Cornwell","year":"2008","journal-title":"Psychol Sci"},{"key":"10.1016\/j.bbr.2011.05.008_bib0330","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1111\/j.1469-8986.1997.tb01737.x","article-title":"Effects of stress and shock anticipation on prepulse inhibition of the startle reflex","volume":"34","author":"Grillon","year":"1997","journal-title":"Psychophysiology"},{"key":"10.1016\/j.bbr.2011.05.008_bib0335","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0361-9230(97)00230-X","article-title":"Excitatory neurotransmission and sexual differentiation of the brain","volume":"44","author":"McCarthy","year":"1997","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.bbr.2011.05.008_bib0340","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1016\/j.neuint.2008.01.001","article-title":"Sex-differences and stress: effects on regional high and low affinity [3H]GABA binding","volume":"52","author":"Skilbeck","year":"2008","journal-title":"Neurochem Int"},{"key":"10.1016\/j.bbr.2011.05.008_bib0345","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.neuroscience.2008.12.058","article-title":"Estrogen impairs glucocorticoid dependent negative feedback on the hypothalamic-pituitary-adrenal axis via estrogen receptor alpha within the hypothalamus","volume":"159","author":"Weiser","year":"2009","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbr.2011.05.008_bib0350","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/S0006-3223(96)00065-0","article-title":"Changes in sensorimotor inhibition across the menstrual cycle: implications for neuropsychiatric disorders","volume":"41","author":"Swerdlow","year":"1997","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.bbr.2011.05.008_bib0355","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0014-2999(01)01139-6","article-title":"Estrogen increases prepulse inhibition of acoustic startle in rats","volume":"425","author":"Van den Buuse","year":"2001","journal-title":"Eur J Pharmacol"},{"issue":"Suppl","key":"10.1016\/j.bbr.2011.05.008_bib0360","doi-asserted-by":"crossref","first-page":"E38","DOI":"10.1111\/j.1749-6632.2010.05568.x","article-title":"Stress, sex, and neural adaptation to a changing environment: mechanisms of neuronal remodeling","volume":"1204","author":"McEwen","year":"2010","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.bbr.2011.05.008_bib0365","first-page":"12","article-title":"Estrogenic modulation of brain activity: implications for schizophrenia and Parkinson's disease","volume":"27","author":"Cyr","year":"2002","journal-title":"J Psychiatry Neurosci"},{"key":"10.1016\/j.bbr.2011.05.008_bib0370","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0304-3940(96)12459-9","article-title":"Acute and chronic effects of estrogenic compounds on glutamate-stimulated phosphatidylinositol metabolism in primary neuronal cultures","volume":"206","author":"Yourick","year":"1996","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.bbr.2011.05.008_bib0375","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1002\/cne.21122","article-title":"Estradiol-induced modulation of estrogen receptor-beta and GABA within the adult neocortex: a potential transsynaptic mechanism for estrogen modulation of BDNF","volume":"499","author":"Blurton-Jones","year":"2006","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.bbr.2011.05.008_bib0380","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1006\/hbeh.1994.1044","article-title":"Gonadal steroid hormone receptors and sex differences in the hypothalamo-pituitary-adrenal axis","volume":"28","author":"Handa","year":"1994","journal-title":"Horm Behav"},{"key":"10.1016\/j.bbr.2011.05.008_bib0385","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0166-4328(96)00164-7","article-title":"A multiple-test study of anxiety-related behaviours in six inbred rat strains","volume":"85","author":"Ramos","year":"1997","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.bbr.2011.05.008_bib0390","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1097\/00008877-200503000-00009","article-title":"Relation of sex and estrous phase to deficits in prepulse inhibition of the startle response induced by ecstasy (MDMA)","volume":"16","author":"Bubenikova","year":"2005","journal-title":"Behav Pharmacol"}],"container-title":["Behavioural Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432811003974?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432811003974?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T19:18:52Z","timestamp":1741202332000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166432811003974"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10]]},"references-count":78,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,10]]}},"alternative-id":["S0166432811003974"],"URL":"https:\/\/doi.org\/10.1016\/j.bbr.2011.05.008","relation":{},"ISSN":["0166-4328"],"issn-type":[{"value":"0166-4328","type":"print"}],"subject":[],"published":{"date-parts":[[2011,10]]}}}