{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T15:34:43Z","timestamp":1792251283537,"version":"4.4.0"},"reference-count":71,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Behavioural Brain Research"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1016\/j.bbr.2012.05.019","type":"journal-article","created":{"date-parts":[[2012,5,17]],"date-time":"2012-05-17T22:23:55Z","timestamp":1337293435000},"page":"305-313","source":"Crossref","is-referenced-by-count":33,"title":["Chronic cannabinoid treatment during young adulthood induces sex-specific behavioural deficits in maternally separated rats"],"prefix":"10.1016","volume":"233","author":[{"given":"Maren","family":"Klug","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maarten","family":"van den Buuse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbr.2012.05.019_bib0005","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1038\/sj.mp.4000473","article-title":"Environment and vulnerability to major psychiatric illness: a case control study of early parental loss in major depression, bipolar disorder and schizophrenia","volume":"4","author":"Agid","year":"1999","journal-title":"Molecular Psychiatry"},{"key":"10.1016\/j.bbr.2012.05.019_bib0010","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.psyneuen.2006.12.013","article-title":"Cognitive impairment associated to HPA axis hyperactivity after maternal separation in rats","volume":"32","author":"Aisa","year":"2007","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0015","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.schres.2008.02.016","article-title":"Duration of early maternal separation and prediction of schizotypal symptoms from early adolescence to midlife","volume":"103","author":"Anglin","year":"2008","journal-title":"Schizophrenia Research"},{"key":"10.1016\/j.bbr.2012.05.019_bib0020","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.neubiorev.2005.03.007","article-title":"Stress, depression, and anhedonia: caveats concerning animal models","volume":"29","author":"Anisman","year":"2005","journal-title":"Neuroscience and Biobehavioral Reviews"},{"key":"10.1016\/j.bbr.2012.05.019_bib0025","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.nbd.2009.11.020","article-title":"Chronic exposure to cannabinoids during adolescence but not during adulthood impairs emotional behaviour and monoaminergic neurotransmission","volume":"37","author":"Bambico","year":"2010","journal-title":"Neurobiology of Disease"},{"key":"10.1016\/j.bbr.2012.05.019_bib0030","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/S0022-3956(99)00039-4","article-title":"Genetic and non-genetic vulnerability factors in schizophrenia: the basis of the two hit hypothesis","volume":"33","author":"Bayer","year":"1999","journal-title":"Journal of Psychiatric Research"},{"key":"10.1016\/j.bbr.2012.05.019_bib0035","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s00213-003-1550-7","article-title":"Chronic treatment with CP 55,940 during the peri-adolescent period differentially affects the behavioural responses of male and female rats in adulthood","volume":"170","author":"Biscaia","year":"2003","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0040","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1007\/s00213-004-1941-4","article-title":"The CB receptor agonist WIN 55,212-2 fails to elicit disruption of prepulse inhibition of the startle in Sprague-Dawley rats","volume":"177","author":"Bortolato","year":"2005","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0045","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1017\/S146114571000091X","article-title":"The schizophrenia susceptibility gene neuregulin 1 modulates tolerance to the effects of cannabinoids","volume":"14","author":"Boucher","year":"2011","journal-title":"International Journal of Neuropsychopharmacology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0050","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1176\/appi.ajp.158.12.2033","article-title":"Cannabis abuse as a risk factor for depressive symptoms","volume":"158","author":"Bovasso","year":"2001","journal-title":"American Journal of Psychiatry"},{"key":"10.1016\/j.bbr.2012.05.019_bib0055","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1001\/archpsyc.1990.01810140081011","article-title":"Sensorimotor gating and schizophrenia. Human and animal model studies","volume":"47","author":"Braff","year":"1990","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.bbr.2012.05.019_bib0060","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1016\/j.neubiorev.2011.04.007","article-title":"Cannabis use in young people: the risk for schizophrenia","volume":"35","author":"Casadio","year":"2011","journal-title":"Neuroscience and Biobehavioral Reviews"},{"key":"10.1016\/j.bbr.2012.05.019_bib0065","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.pbb.2011.07.006","article-title":"Adolescent cannabinoid exposure attenuates adult female sexual motivation but does not alter adulthood CB(1)R expression or estrous cyclicity","volume":"100","author":"Chadwick","year":"2011","journal-title":"Pharmacology Biochemistry and Behavior"},{"key":"10.1016\/j.bbr.2012.05.019_bib0070","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1002\/hipo.20425","article-title":"Combined neonatal stress and young-adult glucocorticoid stimulation in rats reduce BDNF expression in hippocampus: effects on learning and memory","volume":"18","author":"Choy","year":"2008","journal-title":"Hippocampus"},{"key":"10.1016\/j.bbr.2012.05.019_bib0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.euroneuro.2007.03.011","article-title":"Attenuated disruption of prepulse inhibition by dopaminergic stimulation after maternal deprivation and adolescent corticosterone treatment in rats","volume":"18","author":"Choy","year":"2008","journal-title":"European Neuropsychopharmacology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0080","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1111\/j.1476-5381.2008.00008.x","article-title":"The effect of \u2018two hit\u2019 neonatal and young-adult stress on dopaminergic modulation of prepulse inhibition and dopamine receptor density","volume":"156","author":"Choy","year":"2009","journal-title":"British Journal of Pharmacology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0085","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1002\/hup.1048","article-title":"Cannabis and anxiety: a critical review of the evidence","volume":"24","author":"Crippa","year":"2009","journal-title":"Human psychopharmacology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0090","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1046\/j.1360-0443.2003.00437.x","article-title":"Exploring the association between cannabis use and depression","volume":"98","author":"Degenhardt","year":"2003","journal-title":"Addiction"},{"key":"10.1016\/j.bbr.2012.05.019_bib0095","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0140-6736(11)61138-0","article-title":"Extent of illicit drug use and dependence, and their contribution to the global burden of disease","volume":"379","author":"Degenhardt","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.bbr.2012.05.019_bib0100","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/0006-8993(92)91352-F","article-title":"A two-trial memory task with automated recording: study in young and aged rats","volume":"588","author":"Dellu","year":"1992","journal-title":"Brain Research"},{"key":"10.1016\/j.bbr.2012.05.019_bib0105","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1006\/nlme.1999.3919","article-title":"Genetic differences in response to novelty and spatial memory using a two-trial recognition task in mice","volume":"73","author":"Dellu","year":"2000","journal-title":"Neurobiology of Learning and Memory"},{"key":"10.1016\/j.bbr.2012.05.019_bib0110","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1016\/j.neuroscience.2010.08.002","article-title":"Neonatal maternal separation exacerbates the reward-enhancing effect of acute amphetamine administration and the anhedonic effect of repeated social defeat in adult rats","volume":"170","author":"Der-Avakian","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbr.2012.05.019_bib0115","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1007\/s00787-007-0663-7","article-title":"Affect dysregulation in cannabis abusers: a study in adolescents and young adults","volume":"17","author":"Dorard","year":"2008","journal-title":"European Child and Adolescent Psychiatry"},{"key":"10.1016\/j.bbr.2012.05.019_bib0120","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0920-9964(97)00149-7","article-title":"The effects of an early stressful life event on sensorimotor gating in adult rats","volume":"30","author":"Ellenbroek","year":"1998","journal-title":"Schizophrenia Research"},{"key":"10.1016\/j.bbr.2012.05.019_bib0125","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0893-133X(00)00088-9","article-title":"The long-term effects of maternal deprivation depend on the genetic background","volume":"23","author":"Ellenbroek","year":"2000","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0130","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.biopsych.2003.10.024","article-title":"The effects of early maternal deprivation on auditory information processing in adult Wistar rats","volume":"55","author":"Ellenbroek","year":"2004","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.bbr.2012.05.019_bib0135","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0031-9384(00)00205-5","article-title":"Developmental stress disrupts habituation but spares prepulse inhibition in young rats","volume":"69","author":"Finamore","year":"2000","journal-title":"Physiology and Behavior"},{"key":"10.1016\/j.bbr.2012.05.019_bib0140","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1192\/bjp.bp.110.077479","article-title":"Cannabis use before age 15 and subsequent executive functioning","volume":"198","author":"Fontes","year":"2011","journal-title":"British Journal of Psychiatry"},{"key":"10.1016\/j.bbr.2012.05.019_bib0145","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.bbr.2006.10.020","article-title":"Early maternal deprivation reduces prepulse inhibition and impairs spatial learning ability in adulthood: no further effect of post-pubertal chronic corticosterone treatment","volume":"176","author":"Garner","year":"2007","journal-title":"Behavioural Brain Research"},{"key":"10.1016\/j.bbr.2012.05.019_bib0150","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1017\/S0033291709991966","article-title":"Cannabis use and childhood trauma interact additively to increase the risk of psychotic symptoms in adolescence","volume":"40","author":"Harley","year":"2010","journal-title":"Psychological Medicine"},{"key":"10.1016\/j.bbr.2012.05.019_bib0155","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S0006-3223(01)01157-X","article-title":"The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies","volume":"49","author":"Heim","year":"2001","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.bbr.2012.05.019_bib0160","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1136\/bmj.38267.664086.63","article-title":"Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young people","volume":"330","author":"Henquet","year":"2005","journal-title":"BMJ"},{"key":"10.1016\/j.bbr.2012.05.019_bib0165","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1523\/JNEUROSCI.11-02-00563.1991","article-title":"Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study","volume":"11","author":"Herkenham","year":"1991","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.bbr.2012.05.019_bib0170","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.pbb.2009.06.013","article-title":"Chronic periadolescent cannabinoid treatment enhances adult hippocampal PSA-NCAM expression in male Wistar rats but only has marginal effects on anxiety, learning and memory","volume":"93","author":"Higuera-Matas","year":"2009","journal-title":"Pharmacology Biochemistry and Behavior"},{"key":"10.1016\/j.bbr.2012.05.019_bib0175","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.bbr.2010.08.038","article-title":"Maternal separation decreases adult hippocampal cell proliferation and impairs cognitive performance but has little effect on stress sensitivity and anxiety in adult Wistar rats","volume":"216","author":"Hulshof","year":"2011","journal-title":"Behavioural Brain Research"},{"key":"10.1016\/j.bbr.2012.05.019_bib0180","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0091-3057(02)00781-5","article-title":"Long-lasting changes in stress-induced corticosterone response and anxiety-like behaviors as a consequence of neonatal maternal separation in Long-Evans rats","volume":"73","author":"Kalinichev","year":"2002","journal-title":"Pharmacology Biochemistry and Behavior"},{"key":"10.1016\/j.bbr.2012.05.019_bib0185","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1017\/S0033291702006219","article-title":"Childhood parental loss and risk for first-onset of major depression and alcohol dependence: the time-decay of risk and sex differences","volume":"32","author":"Kendler","year":"2002","journal-title":"Psychological Medicine"},{"key":"10.1016\/j.bbr.2012.05.019_bib0190","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.psyneuen.2011.07.011","article-title":"Periodic maternal separation decreases hippocampal neurogenesis without affecting basal corticosterone during the stress hyporesponsive period, but alters HPA axis and coping behavior in adulthood","volume":"37","author":"Lajud","year":"2012","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0195","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.neures.2007.01.008","article-title":"Depressive behaviors and decreased expression of serotonin reuptake transporter in rats that experienced neonatal maternal separation","volume":"58","author":"Lee","year":"2007","journal-title":"Neuroscience Research"},{"key":"10.1016\/j.bbr.2012.05.019_bib0200","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0920-9964(99)00080-8","article-title":"Lack of effect of an early stressful life event on sensorimotor gating in adult rats","volume":"41","author":"Lehmann","year":"2000","journal-title":"Schizophrenia Research"},{"key":"10.1016\/j.bbr.2012.05.019_bib0205","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1111\/j.1369-1600.2011.00318.x","article-title":"Sex-dependent effects of maternal deprivation and adolescent cannabinoid treatment on adult rat behaviour","volume":"16","author":"Llorente-Berzal","year":"2011","journal-title":"Addiction Biology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0210","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1016\/j.neuropharm.2011.07.031","article-title":"Neurobehavioral and metabolic long-term consequences of neonatal maternal deprivation stress and adolescent olanzapine treatment in male and female rats","volume":"62","author":"Llorente-Berzal","year":"2012","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0215","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1177\/0269881110370503","article-title":"Adolescent exposure to nicotine and\/or the cannabinoid agonist CP 55,940 induces gender-dependent long-lasting memory impairments and changes in brain nicotinic and CB(1) cannabinoid receptors","volume":"25","author":"Mateos","year":"2011","journal-title":"Journal of Psychopharmacology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0220","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1093\/oxfordjournals.schbul.a006887","article-title":"Neural development, cell-cell signaling, and the two-hit hypothesis of schizophrenia","volume":"27","author":"Maynard","year":"2001","journal-title":"Schizophrenia Bulletin"},{"key":"10.1016\/j.bbr.2012.05.019_bib0225","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/0091-3057(95)02066-7","article-title":"Aversive effects of the synthetic cannabinoid CP 55,940 in rats","volume":"53","author":"McGregor","year":"1996","journal-title":"Pharmacology Biochemistry and Behavior"},{"key":"10.1016\/j.bbr.2012.05.019_bib0230","doi-asserted-by":"crossref","first-page":"2469","DOI":"10.1038\/npp.2009.70","article-title":"Adolescent exposure to chronic delta-9-tetrahydrocannabinol blocks opiate dependence in maternally deprived rats","volume":"34","author":"Morel","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0235","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0022-3956(99)00032-1","article-title":"The developmental \u2018risk factor\u2019 model of schizophrenia","volume":"33","author":"Murray","year":"1999","journal-title":"Journal of Psychiatric Research"},{"key":"10.1016\/j.bbr.2012.05.019_bib0240","series-title":"Australian code of practice for the care and use of animals for scientific purposes","author":"National Health and Medical Research Council of Australia","year":"2004"},{"key":"10.1016\/j.bbr.2012.05.019_bib0245","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1038\/nn.2886","article-title":"Erroneous analyses of interactions in neuroscience: a problem of significance","volume":"14","author":"Nieuwenhuis","year":"2011","journal-title":"Nature Neuroscience"},{"key":"10.1016\/j.bbr.2012.05.019_bib0250","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1177\/0269881104047277","article-title":"Chronic cannabinoid exposure produces lasting memory impairment and increased anxiety in adolescent but not adult rats","volume":"18","author":"O'Shea","year":"2004","journal-title":"Journal of Psychopharmacology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0255","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1177\/0269881106065188","article-title":"Repeated cannabinoid exposure during perinatal, adolescent or early adult ages produces similar longlasting deficits in object recognition and reduced social interaction in rats","volume":"20","author":"O'Shea","year":"2006","journal-title":"Journal of Psychopharmacology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0260","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1136\/bmj.325.7374.1195","article-title":"Cannabis use and mental health in young people: cohort study","volume":"325","author":"Patton","year":"2002","journal-title":"BMJ"},{"key":"10.1016\/j.bbr.2012.05.019_bib0265","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0169-328X(93)90189-V","article-title":"Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats","volume":"18","author":"Plotsky","year":"1993","journal-title":"Brain Research. Molecular Brain Research"},{"key":"10.1016\/j.bbr.2012.05.019_bib0270","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S0376-8716(02)00334-4","article-title":"Early-onset cannabis use and cognitive deficits: what is the nature of the association","volume":"69","author":"Pope","year":"2003","journal-title":"Drug and Alcohol Dependence"},{"key":"10.1016\/j.bbr.2012.05.019_bib0275","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1038\/sj.npp.1301475","article-title":"Adolescent rats find repeated Delta(9)-THC less aversive than adult rats but display greater residual cognitive deficits and changes in hippocampal protein expression following exposure","volume":"33","author":"Quinn","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0280","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1007\/s11064-010-0364-3","article-title":"Maternal deprivation induces depressive-like behaviour and alters neurotrophin levels in the rat brain","volume":"36","author":"Reus","year":"2011","journal-title":"Neurochemical Research"},{"key":"10.1016\/j.bbr.2012.05.019_bib0285","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0163-7258(02)00253-X","article-title":"The endogenous cannabinoid system and the basal ganglia biochemical, pharmacological, and therapeutic aspects","volume":"95","author":"Romero","year":"2002","journal-title":"Pharmacology & Therapeutics"},{"key":"10.1016\/j.bbr.2012.05.019_bib0290","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/NMD.0b013e3181925342","article-title":"Early adverse experiences in schizophrenia and unipolar depression","volume":"197","author":"Rubino","year":"2009","journal-title":"Journal of Nervous and Mental Disease"},{"key":"10.1016\/j.bbr.2012.05.019_bib0295","doi-asserted-by":"crossref","first-page":"2760","DOI":"10.1038\/sj.npp.1301664","article-title":"Chronic delta 9-tetrahydrocannabinol during adolescence provokes sex-dependent changes in the emotional profile in adult rats: behavioral and biochemical correlates","volume":"33","author":"Rubino","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0300","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1038\/sj.npp.1300225","article-title":"Chronic pubertal, but not adult chronic cannabinoid treatment impairs sensorimotor gating, recognition memory, and the performance in a progressive ratio task in adult rats","volume":"28","author":"Schneider","year":"2003","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0305","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/j.1369-1600.2008.00110.x","article-title":"Puberty as a highly vulnerable developmental period for the consequences of cannabis exposure","volume":"13","author":"Schneider","year":"2008","journal-title":"Addiction Biology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0310","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1369-1600.2008.00117.x","article-title":"Acute and chronic cannabinoid treatment differentially affects recognition memory and social behavior in pubertal and adult rats","volume":"13","author":"Schneider","year":"2008","journal-title":"Addiction Biology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0315","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0091-3057(02)00756-6","article-title":"Repeated maternal separation does not alter sucrose-reinforced and open-field behaviors","volume":"73","author":"Shalev","year":"2002","journal-title":"Pharmacology Biochemistry and Behavior"},{"key":"10.1016\/j.bbr.2012.05.019_bib0320","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.brainres.2006.04.066","article-title":"Long-lasting changes in behavioural and neuroendocrine indices in the rat following neonatal maternal separation: gender-dependent effects","volume":"1097","author":"Slotten","year":"2006","journal-title":"Brain Research"},{"key":"10.1016\/j.bbr.2012.05.019_bib0325","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1111\/j.1360-0443.2004.00683.x","article-title":"Cannabis use and the risk of later schizophrenia: a review","volume":"99","author":"Smit","year":"2004","journal-title":"Addiction"},{"key":"10.1016\/j.bbr.2012.05.019_bib0330","doi-asserted-by":"crossref","first-page":"59","DOI":"10.31887\/DCNS.2006.8.1\/ftremeau","article-title":"A review of emotion deficits in schizophrenia","volume":"8","author":"Tremeau","year":"2006","journal-title":"Dialogues in Clinical Neuroscience"},{"key":"10.1016\/j.bbr.2012.05.019_bib0335","doi-asserted-by":"crossref","first-page":"459","DOI":"10.2174\/1566524033479627","article-title":"Neurodevelopmental animal models of schizophrenia: effects on prepulse inhibition","volume":"3","author":"Van den Buuse","year":"2003","journal-title":"Current Molecular Medicine"},{"key":"10.1016\/j.bbr.2012.05.019_bib0340","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1093\/aje\/kwf043","article-title":"Cannabis use and psychosis: a longitudinal population-based study","volume":"156","author":"van Os","year":"2002","journal-title":"American Journal of Epidemiology"},{"key":"10.1016\/j.bbr.2012.05.019_bib0345","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.brainres.2008.11.081","article-title":"Behavioural disturbances and altered Fos protein expression in adult rats after chronic pubertal cannabinoid treatment","volume":"1253","author":"Wegener","year":"2009","journal-title":"Brain Research"},{"key":"10.1016\/j.bbr.2012.05.019_bib0350","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0031-9384(98)00300-X","article-title":"Periodic maternal deprivation induces gender-dependent alterations in behavioral and neuroendocrine responses to emotional stress in adult rats","volume":"66","author":"Wigger","year":"1999","journal-title":"Physiology and Behavior"},{"key":"10.1016\/j.bbr.2012.05.019_bib0355","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.neuroscience.2011.11.038","article-title":"Gender-dependent behavioral and biochemical effects of adolescent delta-9-tetrahydrocannabinol in adult maternally deprived rats","volume":"204","author":"Zamberletti","year":"2012","journal-title":"Neuroscience"}],"container-title":["Behavioural Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432812003403?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432812003403?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,1,15]],"date-time":"2022-01-15T21:42:05Z","timestamp":1642282925000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166432812003403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":71,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["S0166432812003403"],"URL":"https:\/\/doi.org\/10.1016\/j.bbr.2012.05.019","relation":{},"ISSN":["0166-4328"],"issn-type":[{"value":"0166-4328","type":"print"}],"subject":[],"published":{"date-parts":[[2012,8]]}}}