{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T19:25:04Z","timestamp":1791228304602,"version":"4.1.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Behavioural Brain Research"],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.1016\/j.bbr.2012.07.029","type":"journal-article","created":{"date-parts":[[2012,7,23]],"date-time":"2012-07-23T18:48:14Z","timestamp":1343069294000},"page":"73-81","source":"Crossref","is-referenced-by-count":23,"title":["Factors influencing fluoxetine-induced sexual dysfunction in female rats"],"prefix":"10.1016","volume":"235","author":[{"given":"Sarah","family":"Adams","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danyeal","family":"Heckard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Hassell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynda","family":"Uphouse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbr.2012.07.029_bib0005","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0165-0327(01)00313-5","article-title":"Antidepressant medications: a review of the evidence for drug-induced sexual dysfunction","volume":"69","author":"Montgomery","year":"2002","journal-title":"Journal of Affective Disorders"},{"key":"10.1016\/j.bbr.2012.07.029_bib0010","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.ucl.2007.08.003","article-title":"Sexual dysfunction associated with antidepressant therapy","volume":"34","author":"Segraves","year":"2007","journal-title":"Urologic Clinics of North America"},{"key":"10.1016\/j.bbr.2012.07.029_bib0015","first-page":"182","article-title":"Female sexual dysfunction related to depression and antidepressant medications","volume":"2","author":"Clayton","year":"2002","journal-title":"Current Women's Health Reports"},{"issue":"Suppl. 3","key":"10.1016\/j.bbr.2012.07.029_bib0020","doi-asserted-by":"crossref","first-page":"S314","DOI":"10.1055\/s-2007-970967","article-title":"Depression and sexual dysfunction: aspects of a multi-faceted relationship","volume":"34","author":"Hartmann","year":"2007","journal-title":"Psychiatrische Praxis"},{"issue":"Suppl. 1","key":"10.1016\/j.bbr.2012.07.029_bib0025","doi-asserted-by":"crossref","first-page":"S14","DOI":"10.1016\/j.jad.2011.03.047","article-title":"Barriers to achieving treatment goals: a focus on sleep disturbance and sexual dysfunction","volume":"132","author":"Morehouse","year":"2011","journal-title":"Journal of Affective Disorders"},{"key":"10.1016\/j.bbr.2012.07.029_bib0030","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1345\/aph.1A195","article-title":"Antidepressant-induced sexual dysfunction","volume":"36","author":"Gregorian","year":"2002","journal-title":"Annals of Pharmacotherapy"},{"key":"10.1016\/j.bbr.2012.07.029_bib0035","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.yhbeh.2009.11.009","article-title":"Mixing pleasures: review of the effects of drugs on sex behavior in humans and animal models","volume":"58","author":"Frohmader","year":"2009","journal-title":"Hormones and Behavior"},{"key":"10.1016\/j.bbr.2012.07.029_bib0040","doi-asserted-by":"crossref","first-page":"260","DOI":"10.2174\/187152509789541882","article-title":"Female sexual dysfunction: therapeutic options and experimental challenges","volume":"7","author":"Allahdadi","year":"2009","journal-title":"Cardiovascular and Hematological Agents in Medicinal Chemistry"},{"key":"10.1016\/j.bbr.2012.07.029_bib0045","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1111\/j.1743-6109.2007.00520.x","article-title":"Changes in sexual functioning associated with duloxetine, escitalopram, and placebo in the treatment of patients with major depressive disorder","volume":"4","author":"Clayton","year":"2007","journal-title":"Journal of Sexual Medicine"},{"key":"10.1016\/j.bbr.2012.07.029_bib0050","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1097\/AOG.0b013e3181898cdb","article-title":"Sexual problems and distress in United States women: prevalence and correlates","volume":"112","author":"Shifren","year":"2008","journal-title":"Obstetrics and Gynecology"},{"key":"10.1016\/j.bbr.2012.07.029_bib0055","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1006\/hbeh.1999.1516","article-title":"Appetitive and consummatory sexual behaviors of female rats in bilevel chambers. I. A correlational and factor analysis and the effects of ovarian hormones","volume":"35","author":"Pfaus","year":"1999","journal-title":"Hormones and Behavior"},{"key":"10.1016\/j.bbr.2012.07.029_bib0060","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.pbb.2004.04.013","article-title":"Preclinical models of sexual desire: conceptual and behavioral analyses","volume":"78","author":"Agmo","year":"2004","journal-title":"Pharmacology Biochemistry and Behavior"},{"key":"10.1016\/j.bbr.2012.07.029_bib0065","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.yhbeh.2003.12.010","article-title":"Hormonal status and test condition, but not sexual experience, modulate partner preference in female rats","volume":"45","author":"Clark","year":"2004","journal-title":"Hormones and Behavior"},{"key":"10.1016\/j.bbr.2012.07.029_bib0070","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/0018-506X(89)90037-8","article-title":"Solicitation behavior in the estrous female rat: a review","volume":"23","author":"Erskine","year":"1989","journal-title":"Hormones and Behavior"},{"key":"10.1016\/j.bbr.2012.07.029_bib0075","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1006\/hbeh.2001.1686","article-title":"Conditioning and sexual behavior: a review","volume":"40","author":"Pfaus","year":"2001","journal-title":"Hormones and Behavior"},{"key":"10.1016\/j.bbr.2012.07.029_bib0080","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1196\/annals.1286.004","article-title":"Fluoxetine may influence lordosis of rats through effects on midbrain 3 alpha,5 alpha-THP concentrations","volume":"1007","author":"Frye","year":"2003","journal-title":"Annals of the New York Academy of Sciences"},{"key":"10.1016\/j.bbr.2012.07.029_bib0085","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/S0893-133X(98)00040-2","article-title":"Subchronic administration of fluoxetine impairs estrous behavior in intact female rats","volume":"19","author":"Matuszczyk","year":"1998","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbr.2012.07.029_bib0090","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.brainres.2007.11.033","article-title":"Subchronic treatment with fluoxetine attenuates effects of acute fluoxetine on female rat sexual behavior","volume":"1190","author":"Sarkar","year":"2008","journal-title":"Brain Research"},{"key":"10.1016\/j.bbr.2012.07.029_bib0095","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1111\/j.1743-6109.2010.02192.x","article-title":"Chronic paroxetine treatment does not affect sexual behavior in hormonally sub-primed female rats despite 5-HT(A) receptor desensitization","volume":"8","author":"Snoeren","year":"2011","journal-title":"Journal of Sexual Medicine"},{"key":"10.1016\/j.bbr.2012.07.029_bib0100","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.pbb.2010.01.002","article-title":"Assessment of \u2018active investigation\u2019 as a potential measure of female sexual incentive motivation in a preclinical non-contact rodent model: observations with apomorphine","volume":"95","author":"Hawcock","year":"2010","journal-title":"Pharmacology Biochemistry and Behavior"},{"key":"10.1016\/j.bbr.2012.07.029_bib0105","series-title":"714.14\/VV84. Neuroscience Meeting Planner","article-title":"Modulation of fluoxetine's effect on sexual behavior in female rats","author":"Adams","year":"2011"},{"key":"10.1016\/j.bbr.2012.07.029_bib0110","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.yhbeh.2003.10.001","article-title":"Estrogen and progesterone dose-dependently reduce disruptive effects of restraint on lordosis behavior","volume":"45","author":"White","year":"2004","journal-title":"Hormones and Behavior"},{"key":"10.1016\/j.bbr.2012.07.029_bib0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.yhbeh.2010.03.003","article-title":"Role of 5-HT(1A) receptors in fluoxetine-induced lordosis inhibition","author":"Guptarak","year":"2010","journal-title":"Hormones and Behavior"},{"key":"10.1016\/j.bbr.2012.07.029_bib0120","series-title":"Biostatistical analysis","author":"Zar","year":"1999"},{"key":"10.1016\/j.bbr.2012.07.029_bib0125","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/S0959-4388(97)80141-9","article-title":"Serotonin and motor activity","volume":"7","author":"Jacobs","year":"1997","journal-title":"Current Opinion in Neurobiology"},{"key":"10.1016\/j.bbr.2012.07.029_bib0130","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.pbb.2009.08.008","article-title":"Direct and indirect 5-HT receptor agonists produce gender-specific effects on locomotor and vertical activities in C57 BL\/6J mice","volume":"94","author":"Brookshire","year":"2009","journal-title":"Pharmacology Biochemistry and Behavior"},{"key":"10.1016\/j.bbr.2012.07.029_bib0135","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0091-3057(01)00655-4","article-title":"Acute locomotor effects of fluoxetine, sertraline, and nomifensine in young versus aged Fischer 344 rats","volume":"71","author":"Stanford","year":"2002","journal-title":"Pharmacology Biochemistry and Behavior"},{"key":"10.1016\/j.bbr.2012.07.029_bib0140","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0378-4347(97)00470-2","article-title":"Quantification of fluoxetine and norfluoxetine serum levels by reversed-phase high-performance liquid chromatography with ultraviolet detection","volume":"704","author":"Holladay","year":"1997","journal-title":"Journal of Chromatography B, Biomedical Sciences and Applications"},{"key":"10.1016\/j.bbr.2012.07.029_bib0145","unstructured":"Miryala CS, Hiegel C, Uphouse L. Sprague-Dawley and Fischer females differ in acute effects of fluoxetine on sexual behavior; in press."},{"key":"10.1016\/j.bbr.2012.07.029_bib0150","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.pbb.2011.03.006","article-title":"Acute anxiogenic-like effects of selective serotonin reuptake inhibitors are attenuated by the benzodiazepine diazepam in BALB\/c mice","volume":"98","author":"Birkett","year":"2011","journal-title":"Pharmacology Biochemistry and Behavior"},{"key":"10.1016\/j.bbr.2012.07.029_bib0155","first-page":"88","article-title":"Cellular correlates of enhanced anxiety caused by acute treatment with the selective serotonin reuptake inhibitor fluoxetine in rats","volume":"5","author":"Ravinder","year":"2012","journal-title":"Frontiers in Behavioral Neuroscience"},{"key":"10.1016\/j.bbr.2012.07.029_bib0160","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.bbr.2011.01.051","article-title":"Acute and chronic anxiogenic-like response to fluoxetine in rats in the elevated plus-maze: modulation by stressful handling","volume":"220","author":"Robert","year":"2011","journal-title":"Behavioural Brain Research"},{"key":"10.1016\/j.bbr.2012.07.029_bib0165","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1007\/s00213-005-0247-5","article-title":"5-HT receptor subtypes involved in the anxiogenic-like action and associated Fos response of acute fluoxetine treatment in rats","volume":"185","author":"Salchner","year":"2006","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.bbr.2012.07.029_bib0170","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/0091-3057(81)90019-8","article-title":"Antagonism of estrogen-induced lordosis by corticosterone in adrenalectomized-ovariectomized female rats and mice","volume":"15","author":"deCatanzaro","year":"1981","journal-title":"Pharmacology Biochemistry and Behavior"},{"key":"10.1016\/j.bbr.2012.07.029_bib0175","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0006-8993(85)90414-7","article-title":"Modulation of lordosis behaviour in the female rat by corticotropin releasing factor, beta-endorphin and gonadotropin releasing hormone in the mesencephalic central gray","volume":"336","author":"Sirinathsinghji","year":"1985","journal-title":"Brain Research"},{"key":"10.1016\/j.bbr.2012.07.029_bib0180","first-page":"117","article-title":"Reproduction in mammals","volume":"vol. 5","author":"Uphouse","year":"2011"},{"key":"10.1016\/j.bbr.2012.07.029_bib0185","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0166-4328(99)00087-X","article-title":"What do female rats like about sex? Paced mating","volume":"105","author":"Paredes","year":"1999","journal-title":"Behavioural Brain Research"},{"key":"10.1016\/j.bbr.2012.07.029_bib0190","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0031-9384(00)00242-0","article-title":"Paced mating behavior in the naturally cycling and the hormone-treated female rat","volume":"70","author":"Zipse","year":"2000","journal-title":"Physiology and Behavior"}],"container-title":["Behavioural Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432812004858?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432812004858?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,21]],"date-time":"2018-11-21T18:55:03Z","timestamp":1542826503000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166432812004858"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["S0166432812004858"],"URL":"https:\/\/doi.org\/10.1016\/j.bbr.2012.07.029","relation":{},"ISSN":["0166-4328"],"issn-type":[{"value":"0166-4328","type":"print"}],"subject":[],"published":{"date-parts":[[2012,11]]}}}