{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T21:22:34Z","timestamp":1783286554258,"version":"3.54.6"},"reference-count":56,"publisher":"Elsevier BV","content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Behavioural Brain Research"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1016\/j.bbr.2013.06.004","type":"journal-article","created":{"date-parts":[[2013,6,10]],"date-time":"2013-06-10T02:43:12Z","timestamp":1370832192000},"page":"239-245","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Exercise-induced rescue of tongue function without striatal dopamine sparing in a rat neurotoxin model of Parkinson disease"],"prefix":"10.1016","volume":"252","author":[{"given":"Michelle R.","family":"Ciucci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison J.","family":"Schaser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Russell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbr.2013.06.004_bib0005","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.bbr.2007.01.028","article-title":"Repetitive vibrissae-elicited forelimb placing before and immediately after unilateral 6-hydroxydopamine improves outcome in a model of Parkinson's disease","volume":"179","author":"Anstrom","year":"2007","journal-title":"Behavioural Brain Research"},{"key":"10.1016\/j.bbr.2013.06.004_bib0010","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0892-1997(01)00010-8","article-title":"Voice quality changes following phonatory\u2013respiratory effort treatment (LSVT) versus respiratory effort treatment for individuals with Parkinson disease","volume":"15","author":"Baumgartner","year":"2001","journal-title":"Journal of Voice"},{"key":"10.1016\/j.bbr.2013.06.004_bib0015","doi-asserted-by":"crossref","DOI":"10.1044\/1092-4388(2011\/11-0091)","article-title":"The effect of tongue exercise on serotonergic input to the hypoglossal nucleus in young and old rats","author":"Behan","year":"2012","journal-title":"Journal of Speech, Language, and Hearing Research"},{"key":"10.1016\/j.bbr.2013.06.004_bib0020","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1034\/j.1600-0404.2001.00191.x","article-title":"Causes of death in a community-based study of Parkinson's disease","volume":"103","author":"Beyer","year":"2001","journal-title":"Acta Neurologica Scandinavica"},{"key":"10.1016\/j.bbr.2013.06.004_bib0025","doi-asserted-by":"crossref","first-page":"10999","DOI":"10.1523\/JNEUROSCI.23-35-10999.2003","article-title":"Enriched environment confers resistance to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and cocaine: involvement of dopamine transporter and trophic factors","volume":"23","author":"Bezard","year":"2003","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.bbr.2013.06.004_bib0030","doi-asserted-by":"crossref","first-page":"92","DOI":"10.3389\/fnsys.2011.00092","article-title":"Inter-hemispheric asymmetry of nigrostriatal dopaminergic lesion: a possible compensatory mechanism in Parkinson's disease","volume":"5","author":"Blesa","year":"2011","journal-title":"Frontiers in Systems Neuroscience"},{"key":"10.1016\/j.bbr.2013.06.004_bib0035","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1037\/a0014593","article-title":"Reduction of dopamine synaptic activity: degradation of 50-kHz ultrasonic vocalization in rats","volume":"123","author":"Ciucci","year":"2009","journal-title":"Behavioral Neuroscience"},{"key":"10.1016\/j.bbr.2013.06.004_bib0040","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1007\/s00221-009-1736-2","article-title":"Dopaminergic influence on rat tongue function and limb movement initiation","volume":"194","author":"Ciucci","year":"2009","journal-title":"Experimental Brain Research"},{"issue":"Suppl. 2","key":"10.1016\/j.bbr.2013.06.004_bib0045","doi-asserted-by":"crossref","first-page":"S172","DOI":"10.1016\/j.parkreldis.2008.04.027","article-title":"Limb use and complex ultrasonic vocalization in a rat model of Parkinson's disease: deficit-targeted training","volume":"14","author":"Ciucci","year":"2008","journal-title":"Parkinsonism and Related Disorders"},{"key":"10.1016\/j.bbr.2013.06.004_bib0050","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.bbr.2011.03.057","article-title":"Tongue force and timing deficits in a rat model of Parkinson disease","volume":"222","author":"Ciucci","year":"2011","journal-title":"Behavioural Brain Research"},{"key":"10.1016\/j.bbr.2013.06.004_bib0055","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1046\/j.1471-4159.2003.01657.x","article-title":"Neuroprotective effects of prior limb use in 6-hydroxydopamine-treated rats: possible role of GDNF","volume":"85","author":"Cohen","year":"2003","journal-title":"Journal of Neurochemistry"},{"key":"10.1016\/j.bbr.2013.06.004_bib0060","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1044\/1092-4388(2008\/08-0105)","article-title":"Effect of tongue exercise on protrusive force and muscle fiber area in aging rats","volume":"52","author":"Connor","year":"2009","journal-title":"Journal of Speech, Language, and Hearing Research"},{"key":"10.1016\/j.bbr.2013.06.004_bib0065","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.jvoice.2006.10.010","article-title":"Effects of bilateral subthalamic nucleus stimulation and medication on parkinsonian speech impairment","volume":"22","author":"D\u2019Alatri","year":"2008","journal-title":"Journal of Voice"},{"key":"10.1016\/j.bbr.2013.06.004_bib0070","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s00415-005-0916-7","article-title":"Long-term survival of Parkinson's disease: a population-based study","volume":"253","author":"D\u2019Amelio","year":"2006","journal-title":"Journal of Neurology"},{"key":"10.1016\/j.bbr.2013.06.004_bib0075","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/S0896-6273(03)00568-3","article-title":"Parkinson's disease: mechanisms and models","volume":"39","author":"Dauer","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.bbr.2013.06.004_bib0080","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1002\/1531-8257(200011)15:6<1132::AID-MDS1011>3.0.CO;2-O","article-title":"An investigation of the effects of subthalamic nucleus stimulation on acoustic measures of voice","volume":"15","author":"Dromey","year":"2000","journal-title":"Movement Disorders"},{"key":"10.1016\/j.bbr.2013.06.004_bib0085","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1136\/jnnp.72.1.31","article-title":"Swallowing and voice effects of Lee Silverman Voice Treatment (LSVT): a pilot study","volume":"72","author":"El Sharkawi","year":"2002","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry"},{"key":"10.1016\/j.bbr.2013.06.004_bib0090","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1007\/s00221-005-0179-7","article-title":"Training BIG to move faster: the application of the speed\u2013amplitude relation as a rehabilitation strategy for people with Parkinson's disease","volume":"167","author":"Farley","year":"2005","journal-title":"Experimental Brain Research"},{"key":"10.1016\/j.bbr.2013.06.004_bib0095","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1002\/jnr.20162","article-title":"Exercise-induced behavioral recovery and neuroplasticity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse basal ganglia","volume":"77","author":"Fisher","year":"2004","journal-title":"Journal of Neuroscience Research"},{"key":"10.1016\/j.bbr.2013.06.004_bib0100","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1016\/j.apmr.2008.01.013","article-title":"The effect of exercise training in improving motor performance and corticomotor excitability in people with early Parkinson's disease","volume":"89","author":"Fisher","year":"2008","journal-title":"Archives of Physical Medicine and Rehabilitation"},{"key":"10.1016\/j.bbr.2013.06.004_bib0105","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.bbr.2004.05.024","article-title":"An intermittent, controlled-rate, slow progressive degeneration model of Parkinson's disease: antiparkinson effects of Sinemet and protective effects of methylphenidate","volume":"156","author":"Fleming","year":"2005","journal-title":"Behavioural Brain Research"},{"key":"10.1016\/j.bbr.2013.06.004_bib0110","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1196\/annals.1369.032","article-title":"Nigrostriatal damage with 6-OHDA: validation of routinely applied procedures","volume":"1074","author":"Fulceri","year":"2006","journal-title":"Annals of the New York Academy of Sciences"},{"key":"10.1016\/j.bbr.2013.06.004_bib0115","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1152\/jn.1995.74.2.547","article-title":"Contractile properties of the tongue muscles: effects of hypoglossal nerve and extracellular motoneuron stimulation in rat","volume":"74","author":"Gilliam","year":"1995","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.bbr.2013.06.004_bib0120","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1093\/brain\/103.2.301","article-title":"A physiological mechanism of bradykinesia","volume":"103","author":"Hallett","year":"1980","journal-title":"Brain"},{"key":"10.1016\/j.bbr.2013.06.004_bib0125","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.jcomdis.2010.07.001","article-title":"Subthalamic nucleus deep brain stimulation changes velopharyngeal control in Parkinson's disease","volume":"44","author":"Hammer","year":"2011","journal-title":"Journal of Communication Disorders"},{"key":"10.1016\/j.bbr.2013.06.004_bib0130","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1159\/000266286","article-title":"Speech and swallowing symptoms associated with Parkinson's disease and multiple sclerosis: a survey","volume":"46","author":"Hartelius","year":"1994","journal-title":"Folia Phoniatrica et Logopaedica"},{"key":"10.1016\/j.bbr.2013.06.004_bib0135","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/BF00735878","article-title":"Caffeine produces contralateral rotation in rats with unilateral dopamine denervation: comparisons with apomorphine-induced responses","volume":"94","author":"Herrera-Marschitz","year":"1988","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.bbr.2013.06.004_bib0140","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1136\/jnnp.2007.123323","article-title":"Effects of subthalamic deep brain stimulation on dysarthrophonia in Parkinson's disease","volume":"79","author":"Klostermann","year":"2008","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry"},{"key":"10.1016\/j.bbr.2013.06.004_bib0145","doi-asserted-by":"crossref","first-page":"2777","DOI":"10.1002\/mds.23407","article-title":"Exercise elevates dopamine D2 receptor in a mouse model of Parkinson's disease: in vivo imaging with [18F]fallypride","volume":"25","author":"Li","year":"2010","journal-title":"Movement Disorders"},{"key":"10.1016\/j.bbr.2013.06.004_bib0150","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/0006-8993(79)90782-0","article-title":"Somatosensory inattention after dopamine-depleting intracerebral 6-OHDA injections: spontaneous recovery and pharmacological control","volume":"177","author":"Marshall","year":"1979","journal-title":"Brain Research"},{"key":"10.1016\/j.bbr.2013.06.004_bib0155","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1006\/exnr.2000.7467","article-title":"Alterations in rat striatal glutamate synapses following a lesion of the cortico- and\/or nigrostriatal pathway","volume":"165","author":"Meshul","year":"2000","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.bbr.2013.06.004_bib0160","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1093\/ageing\/afl105","article-title":"Hard to swallow: dysphagia in Parkinson's disease","volume":"35","author":"Miller","year":"2006","journal-title":"Age and Ageing"},{"key":"10.1016\/j.bbr.2013.06.004_bib0165","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1044\/1058-0360(2008\/08-0004)","article-title":"A noninvasive imaging approach to understanding speech changes following deep brain stimulation in Parkinson's disease","volume":"18","author":"Narayana","year":"2009","journal-title":"American Journal of Speech-Language Pathology"},{"key":"10.1016\/j.bbr.2013.06.004_bib0170","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.bbr.2012.07.003","article-title":"Tongue force and tongue motility are differently affected by unilateral vs bilateral nigrostriatal dopamine depletion in rats","volume":"234","author":"Nuckolls","year":"2012","journal-title":"Behavioural Brain Research"},{"key":"10.1016\/j.bbr.2013.06.004_bib0175","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/j.neuroscience.2006.10.042","article-title":"Running wheel exercise enhances recovery from nigrostriatal dopamine injury without inducing neuroprotection","volume":"144","author":"O\u2019Dell","year":"2007","journal-title":"Neuroscience"},{"issue":"Suppl 1","key":"10.1016\/j.bbr.2013.06.004_bib0180","doi-asserted-by":"crossref","first-page":"S41","DOI":"10.1080\/02688690802448335","article-title":"Deep brain stimulation of the pedunculopontine nucleus in Parkinson's disease. Preliminary experience at Oxford","volume":"22","author":"Pereira","year":"2008","journal-title":"British Journal of Neurosurgery"},{"issue":"Suppl. 1","key":"10.1016\/j.bbr.2013.06.004_bib0185","doi-asserted-by":"crossref","first-page":"S141","DOI":"10.1002\/mds.22782","article-title":"Enhancing neuroplasticity in the basal ganglia: the role of exercise in Parkinson's disease","volume":"25","author":"Petzinger","year":"2010","journal-title":"Movement Disorders"},{"key":"10.1016\/j.bbr.2013.06.004_bib0190","doi-asserted-by":"crossref","first-page":"5291","DOI":"10.1523\/JNEUROSCI.1069-07.2007","article-title":"Effects of treadmill exercise on dopaminergic transmission in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury","volume":"27","author":"Petzinger","year":"2007","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.bbr.2013.06.004_bib0195","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S1474-4422(04)00854-3","article-title":"Treatments for dysarthria in Parkinson's disease","volume":"3","author":"Pinto","year":"2004","journal-title":"Lancet Neurology"},{"key":"10.1016\/j.bbr.2013.06.004_bib0200","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1378\/chest.08-1389","article-title":"Impact of expiratory muscle strength training on voluntary cough and swallow function in Parkinson disease","volume":"135","author":"Pitts","year":"2009","journal-title":"Chest"},{"key":"10.1016\/j.bbr.2013.06.004_bib0205","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.bbr.2012.09.031","article-title":"Differential sensitivity of cranial and limb motor function to nigrostriatal dopamine depletion","volume":"237","author":"Plowman","year":"2013","journal-title":"Behavioural Brain Research"},{"key":"10.1016\/j.bbr.2013.06.004_bib0210","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1002\/mds.22617","article-title":"The relationship between quality of life and swallowing in Parkinson's disease","volume":"24","author":"Plowman-Prine","year":"2009","journal-title":"Movement Disorders"},{"key":"10.1016\/j.bbr.2013.06.004_bib0215","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.expneurol.2004.12.006","article-title":"Treadmill training ameliorates dopamine loss but not behavioral deficits in hemi-parkinsonian rats","volume":"193","author":"Poulton","year":"2005","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.bbr.2013.06.004_bib0220","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1212\/WNL.47.6.1496","article-title":"Intensive speech treatment for patients with Parkinson's disease: short-and long-term comparison of two techniques","volume":"47","author":"Ramig","year":"1996","journal-title":"Neurology"},{"key":"10.1016\/j.bbr.2013.06.004_bib0225","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1044\/jshr.3806.1232","article-title":"Comparison of two forms of intensive speech treatment for Parkinson disease","volume":"38","author":"Ramig","year":"1995","journal-title":"Journal of Speech and Hearing Research"},{"key":"10.1016\/j.bbr.2013.06.004_bib0230","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.brainres.2010.03.029","article-title":"Targeted exercise therapy for voice and swallow in persons with Parkinson's disease","volume":"1341","author":"Russell","year":"2010","journal-title":"Brain Research"},{"key":"10.1016\/j.bbr.2013.06.004_bib0235","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s00455-012-9417-x","article-title":"Videofluorographic assessment of rodent swallow in aging and Parkinson disease","volume":"28","author":"Russell","year":"2013","journal-title":"Dysphagia"},{"key":"10.1016\/j.bbr.2013.06.004_bib0240","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/MOO.0b013e3282febd3a","article-title":"Speech and swallowing disorders in Parkinson disease","volume":"16","author":"Sapir","year":"2008","journal-title":"Current Opinion in Otolaryngology and Head and Neck Surgery"},{"key":"10.1016\/j.bbr.2013.06.004_bib0245","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S0028-3908(00)00005-8","article-title":"CNS plasticity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke, cortical ablation, parkinsonism and spinal cord injury","volume":"39","author":"Schallert","year":"2000","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.bbr.2013.06.004_bib0250","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.expneurol.2003.08.017","article-title":"Can the brain be protected through exercise? Lessons from an animal model of parkinsonism","volume":"184","author":"Smith","year":"2003","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.bbr.2013.06.004_bib0255","doi-asserted-by":"crossref","first-page":"6790","DOI":"10.1523\/JNEUROSCI.22-15-06790.2002","article-title":"Forced nonuse in unilateral parkinsonian rats exacerbates injury","volume":"22","author":"Tillerson","year":"2002","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.bbr.2013.06.004_bib0260","doi-asserted-by":"crossref","first-page":"4427","DOI":"10.1523\/JNEUROSCI.21-12-04427.2001","article-title":"Forced limb-use effects on the behavioral and neurochemical effects of 6-hydroxydopamine","volume":"21","author":"Tillerson","year":"2001","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.bbr.2013.06.004_bib0265","first-page":"9","article-title":"Food and water restriction protocols: physiological and behavioral considerations","volume":"39","author":"Toth","year":"2000","journal-title":"Contemporary Topics in Laboratory Animal Science"},{"key":"10.1016\/j.bbr.2013.06.004_bib0270","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1002\/jnr.22216","article-title":"Altered AMPA receptor expression with treadmill exercise in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury","volume":"88","author":"VanLeeuwen","year":"2010","journal-title":"Journal of Neuroscience Research"},{"key":"10.1016\/j.bbr.2013.06.004_bib0275","first-page":"153","article-title":"The interplay between behavior and neurodegeneration in rat models of Parkinson's disease and stroke","volume":"22","author":"Woodlee","year":"2004","journal-title":"Restorative Neurology and Neuroscience"},{"key":"10.1016\/j.bbr.2013.06.004_bib0280","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.neuroimage.2010.11.074","article-title":"Effective connectivity of brain networks during self-initiated movement in Parkinson's disease","volume":"55","author":"Wu","year":"2011","journal-title":"NeuroImage"}],"container-title":["Behavioural Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432813003483?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432813003483?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T03:00:33Z","timestamp":1715482833000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166432813003483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":56,"alternative-id":["S0166432813003483"],"URL":"https:\/\/doi.org\/10.1016\/j.bbr.2013.06.004","relation":{},"ISSN":["0166-4328"],"issn-type":[{"value":"0166-4328","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exercise-induced rescue of tongue function without striatal dopamine sparing in a rat neurotoxin model of Parkinson disease","name":"articletitle","label":"Article Title"},{"value":"Behavioural Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbr.2013.06.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}