{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:49:26Z","timestamp":1792784966663,"version":"4.5.0"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,8,23]],"date-time":"2013-08-23T00:00:00Z","timestamp":1377216000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"funder":[{"name":"Fondation de France; by the ANR FLEXNEURIM","award":["ANR09BLAN034003"],"award-info":[{"award-number":["ANR09BLAN034003"]}],"id":[{"id":"https:\/\/ror.org\/02zkxjz73","id-type":"ROR","asserted-by":"crossref"}]},{"name":"ANR","award":["ANR-08-MNPS-037-01\u2013SynGen"],"award-info":[{"award-number":["ANR-08-MNPS-037-01\u2013SynGen"]}]},{"name":"Neuron-ERANET (EUHF-AUTISM)"},{"name":"Fondation Orange","id":[{"id":"https:\/\/ror.org\/01rqt4198","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Fondation FondaMentale"},{"name":"Fondation Bettencourt\u2013Schueller","id":[{"id":"https:\/\/ror.org\/02p3abx23","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Innovative Medicines Initiative Joint Undertaking","award":["115300"],"award-info":[{"award-number":["115300"]}],"id":[{"id":"https:\/\/ror.org\/019af4n30","id-type":"ROR","asserted-by":"crossref"}]},{"name":"European Union's Seventh Framework Programme","award":["FP7\/2007-2013"],"award-info":[{"award-number":["FP7\/2007-2013"]}]},{"name":"EFPIA companies\u2019"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Behavioural Brain Research"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1016\/j.bbr.2013.08.031","type":"journal-article","created":{"date-parts":[[2013,8,28]],"date-time":"2013-08-28T05:00:29Z","timestamp":1377666029000},"page":"677-689","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":145,"special_numbering":"C","title":["The Autism ProSAP1\/Shank2 mouse model displays quantitative and structural abnormalities in ultrasonic vocalisations"],"prefix":"10.1016","volume":"256","author":[{"given":"Elodie","family":"Ey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Torquet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne-Marie","family":"Le Sourd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire S.","family":"Leblond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias M.","family":"Boeckers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Faure","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Bourgeron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbr.2013.08.031_bib0005","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association WD (2013) Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V).","DOI":"10.1176\/appi.books.9780890425596"},{"key":"10.1016\/j.bbr.2013.08.031_bib0010","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1016\/j.neuron.2011.05.025","article-title":"Solving the autism puzzle a few pieces at a time","volume":"70","author":"Schaaf","year":"2011","journal-title":"Neuron"},{"key":"10.1016\/j.bbr.2013.08.031_bib0015","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1038\/sj.mp.4001896","article-title":"The genetics of autistic disorders and its clinical relevance: a review of the literature","volume":"12","author":"Freitag","year":"2007","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.bbr.2013.08.031_bib0020","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.tig.2010.05.007","article-title":"Key role for gene dosage and synaptic homeostasis in autism spectrum disorders","volume":"26","author":"Toro","year":"2010","journal-title":"Trends Genet"},{"key":"10.1016\/j.bbr.2013.08.031_bib0025","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/ng1933","article-title":"Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders","volume":"39","author":"Durand","year":"2007","journal-title":"Nat Genet"},{"key":"10.1016\/j.bbr.2013.08.031_bib0030","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1002\/ajmg.b.30822","article-title":"Novel de novo SHANK3 mutation in autistic patients","volume":"150B","author":"Gauthier","year":"2009","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"10.1016\/j.bbr.2013.08.031_bib0035","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1086\/522590","article-title":"Contribution of SHANK3 mutations to autism spectrum disorder","volume":"81","author":"Moessner","year":"2007","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.bbr.2013.08.031_bib0040","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1038\/ng.589","article-title":"Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation","volume":"42","author":"Berkel","year":"2010","journal-title":"Nat Genet"},{"key":"10.1016\/j.bbr.2013.08.031_bib0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pgen.1002521","article-title":"Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders","volume":"8","author":"Leblond","year":"2012","journal-title":"PLoS Genet"},{"key":"10.1016\/j.bbr.2013.08.031_bib0050","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/nature09146","article-title":"Functional impact of global rare copy number variation in autism spectrum disorders","volume":"466","author":"Pinto","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.bbr.2013.08.031_bib0055","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.ajhg.2012.03.017","article-title":"SHANK1 deletions in males with autism spectrum disorder","volume":"90","author":"Sato","year":"2012","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.bbr.2013.08.031_bib0060","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1016\/j.cell.2011.03.052","article-title":"Enhanced polyubiquitination of Shank3 and NMDA receptor in a mouse model of autism","volume":"145","author":"Bangash","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.bbr.2013.08.031_bib0065","doi-asserted-by":"crossref","first-page":"U437","DOI":"10.1038\/nature09965","article-title":"Shank3 mutant mice display autistic-like behaviours and striatal dysfunction","volume":"472","author":"Peca","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.bbr.2013.08.031_bib0070","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/nature11015","article-title":"Autistic-like behaviours and hyperactivity in mice lacking ProSAP1\/Shank2","volume":"486","author":"Schmeisser","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.bbr.2013.08.031_bib0075","doi-asserted-by":"crossref","first-page":"3093","DOI":"10.1093\/hmg\/ddr212","article-title":"Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3","volume":"20","author":"Wang","year":"2011","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.bbr.2013.08.031_bib0080","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1038\/nature11208","article-title":"Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function","volume":"486","author":"Won","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.bbr.2013.08.031_bib0085","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1523\/JNEUROSCI.3032-07.2008","article-title":"Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1","volume":"28","author":"Hung","year":"2008","journal-title":"J Neurosci"},{"key":"10.1016\/j.bbr.2013.08.031_bib0090","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.brainres.2010.09.026","article-title":"Sociability and motor functions in Shank1 mutant mice","volume":"1380","author":"Silverman","year":"2011","journal-title":"Brain Res"},{"key":"10.1016\/j.bbr.2013.08.031_bib0095","doi-asserted-by":"crossref","first-page":"e20631","DOI":"10.1371\/journal.pone.0020631","article-title":"Communication impairments in mice lacking Shank1: reduced levels of ultrasonic vocalizations and scent marking behavior","volume":"6","author":"W\u00f6hr","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.bbr.2013.08.031_bib0100","doi-asserted-by":"crossref","first-page":"6525","DOI":"10.1523\/JNEUROSCI.6107-11.2012","article-title":"Reduced excitatory neurotransmission and mild autism-relevant phenotypes in adolescent Shank3 null mutant mice","volume":"32","author":"Yang","year":"2012","journal-title":"J Neurosci"},{"key":"10.1016\/j.bbr.2013.08.031_bib0105","first-page":"217","article-title":"Autistic disturbances of affective contact","volume":"2","author":"Kanner","year":"1943","journal-title":"Nervous Child"},{"key":"10.1016\/j.bbr.2013.08.031_bib0110","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1007\/s11065-011-9178-6","article-title":"The ontogenesis of language impairment in autism: a neuropsychological perspective","volume":"21","author":"Stefanatos","year":"2011","journal-title":"Neuropsychol Rev"},{"key":"10.1016\/j.bbr.2013.08.031_bib0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fnhum.2010.00237","article-title":"Abnormal speech spectrum and increased pitch variability in young autistic children","volume":"4","author":"Bonneh","year":"2011","journal-title":"Front Hum Neurosc"},{"key":"10.1016\/j.bbr.2013.08.031_bib0120","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1007\/BF00632534","article-title":"Ultraschall-Laute bei jungen M\u00e4usen","volume":"43","author":"Zippelius","year":"1956","journal-title":"Naturwissenschaften"},{"key":"10.1016\/j.bbr.2013.08.031_bib0125","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/BF00619131","article-title":"Ultrasound recognition in house mice \u2013 key-stimulus configuration and recognition mechanism","volume":"148","author":"Ehret","year":"1982","journal-title":"J Comp Physiol"},{"key":"10.1016\/j.bbr.2013.08.031_bib0130","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1038\/227410a0","article-title":"Ultrasonic communication in rodents","volume":"227","author":"Sewell","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.bbr.2013.08.031_bib0135","series-title":"Ultrasonic communication by animals","author":"Sales","year":"1974"},{"key":"10.1016\/j.bbr.2013.08.031_bib0140","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.1371\/journal.pbio.0030386","article-title":"Ultrasonic songs of male mice","volume":"3","author":"Holy","year":"2005","journal-title":"PLoS Biol"},{"key":"10.1016\/j.bbr.2013.08.031_bib0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0000351","article-title":"Affiliative behavior, ultrasonic communication and social reward are influenced by genetic variation in adolescent mice","volume":"2","author":"Panksepp","year":"2007","journal-title":"Plos One"},{"key":"10.1016\/j.bbr.2013.08.031_bib0150","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.bbr.2007.01.020","article-title":"Ultrasonic vocalizations emitted during dyadic interactions in female mice: a possible index of sociability?","volume":"182","author":"Moles","year":"2007","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.bbr.2013.08.031_bib0155","first-page":"28","article-title":"Types and functions of ultrasonic vocalizations in laboratory rats and mice","volume":"46","author":"Portfors","year":"2007","journal-title":"J Am Assoc Lab Anim Sci"},{"key":"10.1016\/j.bbr.2013.08.031_bib0160","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1098\/rsbl.2009.0317","article-title":"Female mice respond to male ultrasonic \u2018songs\u2019 with approach behaviour","volume":"5","author":"Hammerschmidt","year":"2009","journal-title":"Biol Lett"},{"key":"10.1016\/j.bbr.2013.08.031_bib0165","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0029401","article-title":"Adult male mice emit context-specific ultrasonic vocalizations that are modulated by prior isolation or group rearing environment","volume":"7","author":"Chabout","year":"2012","journal-title":"Plos One"},{"key":"10.1016\/j.bbr.2013.08.031_bib0170","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/j.1601-183X.2010.00623.x","article-title":"Unusual repertoire of vocalizations in adult BTBR T plus tf\/J mice during three types of social encounters","volume":"10","author":"Scattoni","year":"2010","journal-title":"Genes Brain Behav"},{"key":"10.1016\/j.bbr.2013.08.031_bib0175","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1002\/aur.175","article-title":"Behavioral profiles of mouse models for autism spectrum disorders","volume":"4","author":"Ey","year":"2011","journal-title":"Autism Res"},{"key":"10.1016\/j.bbr.2013.08.031_bib0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0003067","article-title":"Unusual repertoire of vocalizations in the BTBR T plus tf\/J mouse model of autism","volume":"3","author":"Scattoni","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.bbr.2013.08.031_bib0185","first-page":"007","article-title":"Modelling social communication deficits in mouse models of autism","volume":"S1","author":"Michetti","year":"2012","journal-title":"Autism"},{"key":"10.1016\/j.bbr.2013.08.031_bib0190","series-title":"Contemporary clinical neuroscience: transgenic and knockout models of neuropsychiatric disorders","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/978-1-59745-058-4_8","article-title":"Animal models of autism \u2013 proposed behavioral paradigms and biological studies","author":"Bourgeron","year":"2006"},{"key":"10.1016\/j.bbr.2013.08.031_bib0195","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1111\/j.1601-183X.2012.00849.x","article-title":"Absence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4","volume":"11","author":"Ey","year":"2012","journal-title":"Genes Brain Behav"},{"key":"10.1016\/j.bbr.2013.08.031_bib0200","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0041133","article-title":"The structure and usage of female and male mouse ultrasonic vocalizations reveal only minor differences","volume":"7","author":"Hammerschmidt","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bbr.2013.08.031_bib0205","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0031-9384(89)90164-9","article-title":"The emission and elicitation of mouse ultrasonic vocalizations \u2013 the effects of age, sex and gonadal status","volume":"45","author":"Warburton","year":"1989","journal-title":"Physiol Behav"},{"key":"10.1016\/j.bbr.2013.08.031_bib0210","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0017460","article-title":"Development of social vocalizations in mice","volume":"6","author":"Grimsley","year":"2011","journal-title":"Plos One"},{"key":"10.1016\/j.bbr.2013.08.031_bib0215","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/ajp.1350370303","article-title":"Vocal production in non-human primates \u2013 acoustics, physiology, and functional constraints on honest advertisement","volume":"37","author":"Fitch","year":"1995","journal-title":"Am J Primatol"},{"key":"10.1016\/j.bbr.2013.08.031_bib0220","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1002\/dev.420150306","article-title":"Temporal organization of ultrasonic vocalizations in infant mice","volume":"15","author":"Elwood","year":"1982","journal-title":"Dev Psychobiol"},{"key":"10.1016\/j.bbr.2013.08.031_bib0225","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1007\/s00114-004-0543-7","article-title":"Spectrographic analysis of the ultrasonic vocalisations of adult male and female BALB\/c mice","volume":"91","author":"Gourbal","year":"2004","journal-title":"Naturwissenschaften"},{"key":"10.1016\/j.bbr.2013.08.031_bib0230","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1007\/s10764-007-9139-3","article-title":"Age- and sex-related variations in clear calls of Papio ursinus","volume":"28","author":"Ey","year":"2007","journal-title":"Int J Primatol"},{"key":"10.1016\/j.bbr.2013.08.031_bib0235","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/S0387-7604(02)00191-2","article-title":"Update on the language disorders of individuals on the autistic spectrum","volume":"25","author":"Rapin","year":"2003","journal-title":"Brain Dev"},{"key":"10.1016\/j.bbr.2013.08.031_bib0240","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1126\/science.1138389","article-title":"Reversal of neurological defects in a mouse model of rett syndrome","volume":"315","author":"Guy","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.bbr.2013.08.031_bib0245","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1126\/science.1224159","article-title":"Shared synaptic pathophysiology in syndromic and nonsyndromic rodent models of autism","volume":"338","author":"Baudouin","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.bbr.2013.08.031_bib0250","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/nm.3193","article-title":"Progress toward treatments for synaptic defects in autism","volume":"19","author":"Delorme","year":"2013","journal-title":"Nat Med"},{"key":"10.1016\/j.bbr.2013.08.031_bib0255","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.cell.2009.03.041","article-title":"A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice","volume":"137","author":"Enard","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.bbr.2013.08.031_bib0260","doi-asserted-by":"crossref","first-page":"e44816","DOI":"10.1371\/journal.pone.0044816","article-title":"Comprehensive analysis of ultrasonic vocalizations in a mouse model of fragile X syndrome reveals limited, call type specific deficits","volume":"7","author":"Roy","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bbr.2013.08.031_bib0265","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/j.1601-183X.2010.00603.x","article-title":"Translating mouse vocalizations: prosody and frequency modulation1","volume":"10","author":"Lahvis","year":"2011","journal-title":"Genes Brain Behav"},{"key":"10.1016\/j.bbr.2013.08.031_bib0270","doi-asserted-by":"crossref","first-page":"e46610","DOI":"10.1371\/journal.pone.0046610","article-title":"Of mice, birds, and men: the mouse ultrasonic song system has some features similar to humans and song-learning birds","volume":"7","author":"Arriaga","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bbr.2013.08.031_bib0275","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0378-5955(03)00365-4","article-title":"Age-related hearing loss and the ahl locus in mice","volume":"188","author":"Keithley","year":"2004","journal-title":"Hear Res"},{"key":"10.1016\/j.bbr.2013.08.031_bib0280","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1471-2202-13-40","article-title":"Mice do not require auditory input for the normal development of their ultrasonic vocalizations","volume":"13","author":"Hammerschmidt","year":"2012","journal-title":"BMC Neuroscience"}],"container-title":["Behavioural Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432813005287?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432813005287?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T06:06:06Z","timestamp":1715925966000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166432813005287"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":56,"alternative-id":["S0166432813005287"],"URL":"https:\/\/doi.org\/10.1016\/j.bbr.2013.08.031","relation":{},"ISSN":["0166-4328"],"issn-type":[{"value":"0166-4328","type":"print"}],"subject":[],"published":{"date-parts":[[2013,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Autism ProSAP1\/Shank2 mouse model displays quantitative and structural abnormalities in ultrasonic vocalisations","name":"articletitle","label":"Article Title"},{"value":"Behavioural Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbr.2013.08.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}