{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T07:21:39Z","timestamp":1789543299118,"version":"build-2803163510"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Brazilian Council for Scientific and Technological Development (CNPq\/Program Science without Borders)"},{"DOI":"10.13039\/501100007384","name":"FAPERJ\/PRONEX, INCT\/CNPq\/National Institute of Translational Neuroscience","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100007384","id-type":"DOI","asserted-by":"crossref"}]},{"name":"INCT\/CNPq\/National Institute of Translational Medicine"},{"DOI":"10.13039\/501100000690","name":"Research Council UK","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000690","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Medical Research Council"},{"name":"Psychiatry Research Trust"},{"name":"Welton Foundation"},{"name":"Brain & Behavior Research Foundation (formerly NARSAD)"},{"DOI":"10.13039\/501100000288","name":"Royal Society","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000288","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Behavioural Brain Research"],"published-print":{"date-parts":[[2014,4]]},"DOI":"10.1016\/j.bbr.2014.01.012","type":"journal-article","created":{"date-parts":[[2014,1,23]],"date-time":"2014-01-23T15:05:09Z","timestamp":1390489509000},"page":"34-45","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"special_numbering":"C","title":["Hippocampal biomarkers of fear memory in an animal model of generalized anxiety disorder"],"prefix":"10.1016","volume":"263","author":[{"given":"Gisele Pereira","family":"Dias","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rio Cesar do Nascimento","family":"Bevilaqua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Claudia Domingos Silveira","family":"da Luz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata Lopes","family":"Fleming","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00edtia Alves","family":"de Carvalho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham","family":"Cocks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Beckman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas Costa","family":"Hosken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"de Sant\u2019Anna Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Carolina","family":"Corr\u00eaa-e-Castro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felippe","family":"Mousovich-Neto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00edtor","family":"de Castro Gomes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilmara de Nazareth Tavares","family":"Bastos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regina C\u00e9lia Cussa","family":"Kubrusly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e2nia Maria Corr\u00eaa","family":"da Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak","family":"Srivastava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesus","family":"Landeira-Fernandez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio Egidio","family":"Nardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandrine","family":"Thuret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia Franca","family":"Gardino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbr.2014.01.012_bib0005","doi-asserted-by":"crossref","first-page":"S101","DOI":"10.1016\/j.euroneuro.2006.04.002","article-title":"Generalized anxiety disorder: what are we missing?","volume":"16","author":"Allgulander","year":"2006","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.bbr.2014.01.012_bib0010","doi-asserted-by":"crossref","first-page":"228","DOI":"10.3758\/s13415-011-0021-6","article-title":"Contextual conditioning in rats as an animal model for generalized anxiety disorder","volume":"11","author":"Luyten","year":"2011","journal-title":"Cogn Affect Behav Neurosci"},{"key":"10.1016\/j.bbr.2014.01.012_bib0015","first-page":"173","article-title":"Transtorno de ansiedade generalizada: quest\u00f5es te\u00f3ricas e diagn\u00f3sticas","volume":"45","author":"Nardi","year":"1996","journal-title":"J Bras Psiquiatr"},{"key":"10.1016\/j.bbr.2014.01.012_bib0020","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1097\/00004850-200015060-00002","article-title":"Disabilities and quality of life in pure and comorbid generalized anxiety disorder and major depression in a national survey","volume":"15","author":"Wittchen","year":"2000","journal-title":"Int Clin Psychopharmacol"},{"key":"10.1016\/j.bbr.2014.01.012_bib0025","doi-asserted-by":"crossref","first-page":"15","DOI":"10.4088\/JCP.s.7002.03","article-title":"Neurobiology of generalized anxiety disorder","volume":"70","author":"Stein","year":"2009","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.bbr.2014.01.012_bib0030","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1177\/0269881108101796","article-title":"A pilot study of the effects of chronic paroxetine administration on hippocampal N-acetylaspartate in generalized anxiety disorder","volume":"24","author":"Mathew","year":"2010","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.bbr.2014.01.012_bib0035","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1177\/1534582306289043","article-title":"What is the functional significance of chronic stress-induced CA3 dendritic retraction within the hippocampus?","volume":"5","author":"Conrad","year":"2006","journal-title":"Behav Cogn Neurosci Rev"},{"key":"10.1016\/j.bbr.2014.01.012_bib0040","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0006-8993(98)00515-0","article-title":"Metyrapone pretreatment prevents the behavioral and neurochemical sequelae induced by stress","volume":"800","author":"Calvo","year":"1998","journal-title":"Brain Res"},{"key":"10.1016\/j.bbr.2014.01.012_bib0045","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/0306-4522(95)00256-I","article-title":"Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: comparison of stressors","volume":"69","author":"Magari\u00f1os","year":"1995","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbr.2014.01.012_bib0050","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1097\/WNR.0b013e32836384db","article-title":"Systematic correlation between spine plasticity and the anxiety\/depression-like phenotype induced by corticosterone in mice","volume":"24","author":"Wang","year":"2013","journal-title":"Neuroreport"},{"key":"10.1016\/j.bbr.2014.01.012_bib0055","doi-asserted-by":"crossref","first-page":"5455","DOI":"10.1523\/JNEUROSCI.5123-04.2005","article-title":"ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin","volume":"25","author":"Teng","year":"2005","journal-title":"J Neurosci"},{"key":"10.1016\/j.bbr.2014.01.012_bib0060","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/nrn1300","article-title":"Genesis of dendritic spines: insights from ultrastructural and imaging studies","volume":"5","author":"Yuste","year":"2004","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.bbr.2014.01.012_bib0065","doi-asserted-by":"crossref","first-page":"5219","DOI":"10.1523\/JNEUROSCI.22-12-05219.2002","article-title":"The group I metabotropic glutamate receptor mGluR5 is required for fear memory formation and long-term potentiation in the lateral amygdala","volume":"22","author":"Rodrigues","year":"2002","journal-title":"J Neurosci"},{"key":"10.1016\/j.bbr.2014.01.012_bib0070","doi-asserted-by":"crossref","first-page":"15886","DOI":"10.1523\/JNEUROSCI.4505-11.2012","article-title":"Neurodevelopmental role for VGLUT2 in pyramidal neuron plasticity, dendritic refinement, and in spatial learning","volume":"32","author":"He","year":"2012","journal-title":"J Neurosci"},{"key":"10.1016\/j.bbr.2014.01.012_bib0075","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1124\/mol.105.017194","article-title":"Synaptic expression of glutamate receptor after encoding of fear memory in the rat amygdala","volume":"69","author":"Yeh","year":"2006","journal-title":"Mol Pharmacol"},{"key":"10.1016\/j.bbr.2014.01.012_bib0080","doi-asserted-by":"crossref","first-page":"13208","DOI":"10.1073\/pnas.0605180103","article-title":"Transgenic brain-derived neurotrophic factor expression causes both anxiogenic and antidepressant effects","volume":"103","author":"Govindarajan","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.bbr.2014.01.012_bib0085","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.neuroscience.2012.09.017","article-title":"Are BDNF and glucocorticoid activities calibrated?","volume":"239","author":"Jeanneteau","year":"2012","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbr.2014.01.012_bib0090","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/7854_2009_8","article-title":"The pharmacology of anxiety","volume":"2","author":"Durant","year":"2010","journal-title":"Curr Top Behav Neurosci"},{"key":"10.1016\/j.bbr.2014.01.012_bib0095","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/nrd1630","article-title":"Metabotropic glutamate receptors as novel targets for anxiety and stress disorders","volume":"4","author":"Swanson","year":"2005","journal-title":"Nat Rev Drug Discov"},{"key":"10.1016\/j.bbr.2014.01.012_bib0100","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1038\/mp.2009.15","article-title":"Adult hippocampal neurogenesis is involved in anxiety-related behaviors","volume":"14","author":"Revest","year":"2009","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.bbr.2014.01.012_bib0105","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbr.2007.10.018","article-title":"Different patterns of freezing behavior organized in the periaqueductal gray of rats: association with different types of anxiety","volume":"188","author":"Brand\u00e3o","year":"2008","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.bbr.2014.01.012_bib0110","series-title":"Mental and behavioural disorders and diseases of the nervous system","first-page":"324","article-title":"The Carioca high and low conditioned freezing lines: a new animal model of generalized anxiety disorder","author":"de Castro Gomes","year":"2011"},{"key":"10.1016\/j.bbr.2014.01.012_bib0115","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.brainres.2008.07.044","article-title":"Amygdaloid lesions produced similar contextual fear conditioning disruption in the Carioca high- and low-conditioned freezing rats","volume":"1233","author":"de Castro Gomes","year":"2008","journal-title":"Brain Res"},{"key":"10.1016\/j.bbr.2014.01.012_bib0120","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1038\/nprot.2006.116","article-title":"Morris water maze: procedures for assessing spatial and related forms of learning and memory","volume":"1","author":"Vorhees","year":"2006","journal-title":"Nat Protoc"},{"key":"10.1016\/j.bbr.2014.01.012_bib0125","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.brat.2012.10.004","article-title":"Cognitive-behavior therapy resolves implicit fear associations in generalized anxiety disorder","volume":"51","author":"Reinecke","year":"2013","journal-title":"Behav Res Ther"},{"key":"10.1016\/j.bbr.2014.01.012_bib0130","doi-asserted-by":"crossref","first-page":"35964","DOI":"10.1074\/jbc.M112.363358","article-title":"Afadin is required for maintenance of dendritic structure and excitatory tone","volume":"287","author":"Srivastava","year":"2012","journal-title":"J Biol Chem"},{"key":"10.1016\/j.bbr.2014.01.012_bib0135","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1002\/hipo.20550","article-title":"Hippocampus-dependent learning is associated with adult neurogenesis in MRL\/MpJ mice","volume":"19","author":"Thuret","year":"2009","journal-title":"Hippocampus"},{"key":"10.1016\/j.bbr.2014.01.012_bib0140","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal Biochem"},{"key":"10.1016\/j.bbr.2014.01.012_bib0145","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1016\/j.brat.2004.10.007","article-title":"Classical fear conditioning in the anxiety disorders: a meta-analysis","volume":"43","author":"Lissek","year":"2005","journal-title":"Behav Res Ther"},{"key":"10.1016\/j.bbr.2014.01.012_bib0150","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1080\/16506070601070459","article-title":"Memory bias for threat in generalized anxiety disorder: the potential importance of stimulus relevance","volume":"36","author":"Coles","year":"2007","journal-title":"Cogn Behav Ther"},{"key":"10.1016\/j.bbr.2014.01.012_bib0155","series-title":"Basic neurochemistry: molecular, cellular, and medical aspects","first-page":"1003","article-title":"Endocrine effects on the brain and their relationship to behavior","author":"McEwen","year":"1993"},{"key":"10.1016\/j.bbr.2014.01.012_bib0160","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1749-6632.1994.tb39204.x","article-title":"Brain mineralocorticoid receptor function","volume":"746","author":"De Kloet","year":"1994","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.bbr.2014.01.012_bib0165","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0149-7634(01)00002-1","article-title":"Corticosteroids in relation to fear, anxiety and psychopathology","volume":"25","author":"Korte","year":"2001","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.bbr.2014.01.012_bib0170","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1038\/nn.3262","article-title":"Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders","volume":"15","author":"Kheirbek","year":"2012","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.bbr.2014.01.012_bib0175","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0006-8993(92)91597-8","article-title":"Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons","volume":"588","author":"Watanabe","year":"1992","journal-title":"Brain Res"},{"key":"10.1016\/j.bbr.2014.01.012_bib0180","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1038\/mp.2008.119","article-title":"The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling","volume":"14","author":"Bessa","year":"2009","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.bbr.2014.01.012_bib0185","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0306-4522(00)00050-6","article-title":"Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement","volume":"97","author":"Sousa","year":"2000","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbr.2014.01.012_bib0190","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.bbr.2011.09.009","article-title":"Dendritic morphology of amygdala and hippocampal neurons in more and less predator stress responsive rats and more and less spontaneously anxious handled controls","volume":"226","author":"Adamec","year":"2012","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.bbr.2014.01.012_bib0195","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.bbr.2009.06.038","article-title":"Behavioral profile and dorsal hippocampal cells in Carioca high-conditioned freezing rats","volume":"205","author":"Dias","year":"2009","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.bbr.2014.01.012_bib0200","doi-asserted-by":"crossref","first-page":"10825","DOI":"10.1073\/pnas.152112399","article-title":"Reduced fear expression after lesions of the ventral hippocampus","volume":"99","author":"Kjelstrup","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.bbr.2014.01.012_bib0205","article-title":"Paternal deprivation affects the functional maturation of corticotropin-releasing hormone (CRH)- and calbindin-D28k-expressing neurons in the bed nucleus of the stria terminalis (BNST) of the biparental Octodon degus","volume":"8","author":"Gos","year":"2013","journal-title":"Brain Struct Funct"},{"key":"10.1016\/j.bbr.2014.01.012_bib0210","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/sj.npp.1300290","article-title":"Alterations in central neuropetpide expression, release, and receptor binding in rats bred for high anxiety: critical role of vasopressin","volume":"29","author":"Wigger","year":"2004","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbr.2014.01.012_bib0215","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1023\/A:1020258104318","article-title":"High\u00d7low anxiety-related behavior rats: an animal model of extremes in trait anxiety","volume":"32","author":"Landgraf","year":"2002","journal-title":"Behav Genet"},{"key":"10.1016\/j.bbr.2014.01.012_bib0220","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1080\/1025389031000104193","article-title":"Born to be anxious: neuroendocrine and genetic correlates of trait anxiety in HAB rats","volume":"6","author":"Landgraf","year":"2003","journal-title":"Stress"},{"key":"10.1016\/j.bbr.2014.01.012_bib0225","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1515\/REVNEURO.2008.19.6.395","article-title":"Chronic stress-induced hippocampal vulnerability: the glucocorticoid vulnerability hypothesis","volume":"19","author":"Conrad","year":"2008","journal-title":"Rev Neurosci"},{"key":"10.1016\/j.bbr.2014.01.012_bib0230","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1038\/nature10287","article-title":"Adult hippocampal neurogenesis buffers stress responses and depressive behaviour","volume":"476","author":"Snyder","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.bbr.2014.01.012_bib0235","first-page":"1","article-title":"fosB-null mice display impaired adult hippocampal neurogenesis and spontaneous epilepsy with depressive behavior","author":"Yutsudo","year":"2013","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbr.2014.01.012_bib0240","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/hipo.20140","article-title":"Age-related naturally occurring depression of hippocampal neurogenesis does not affect trace fear conditioning","volume":"16","author":"Cuppini","year":"2006","journal-title":"Hippocampus"},{"key":"10.1016\/j.bbr.2014.01.012_bib0245","doi-asserted-by":"crossref","first-page":"6635","DOI":"10.1523\/JNEUROSCI.0247-10.2010","article-title":"Severe early life stress hampers spatial learning and neurogenesis, but improves hippocampal synaptic plasticity and emotional learning under high-stress conditions in adulthood","volume":"30","author":"Oomen","year":"2010","journal-title":"J Neurosci"},{"key":"10.1016\/j.bbr.2014.01.012_bib0250","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1038\/nn1971","article-title":"New insights into BDNF function in depression and anxiety","volume":"10","author":"Martinowich","year":"2007","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.bbr.2014.01.012_bib0255","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1126\/science.1100135","article-title":"Cleavage of proBDNF by tPA\/plasmin is essential for long-term hippocampal plasticity","volume":"306","author":"Pang","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.bbr.2014.01.012_bib0260","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1749-6632.2001.tb05830.x","article-title":"Plasticity of the hippocampus: adaptation to chronic stress and allostatic load","volume":"933","author":"McEwen","year":"2001","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.bbr.2014.01.012_bib0265","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.bbr.2011.05.013","article-title":"Adult neurogenesis: optimizing hippocampal function to suit the environment","volume":"227","author":"Glasper","year":"2012","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.bbr.2014.01.012_bib0270","doi-asserted-by":"crossref","first-page":"2611","DOI":"10.1111\/ejn.12259","article-title":"Fear extinction deficits following acute stress associate with increased spine density and dendritic retraction in basolateral amygdala neurons","volume":"38","author":"Maroun","year":"2013","journal-title":"Eur J Neurosci"}],"container-title":["Behavioural Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432814000151?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432814000151?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,8,14]],"date-time":"2020-08-14T10:48:58Z","timestamp":1597402138000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166432814000151"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4]]},"references-count":54,"alternative-id":["S0166432814000151"],"URL":"https:\/\/doi.org\/10.1016\/j.bbr.2014.01.012","relation":{},"ISSN":["0166-4328"],"issn-type":[{"value":"0166-4328","type":"print"}],"subject":[],"published":{"date-parts":[[2014,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hippocampal biomarkers of fear memory in an animal model of generalized anxiety disorder","name":"articletitle","label":"Article Title"},{"value":"Behavioural Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbr.2014.01.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}