{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T01:30:46Z","timestamp":1791855046782,"version":"4.3.4"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31100598"],"award-info":[{"award-number":["31100598"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Behavioural Brain Research"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1016\/j.bbr.2014.11.016","type":"journal-article","created":{"date-parts":[[2014,11,17]],"date-time":"2014-11-17T14:52:55Z","timestamp":1416235975000},"page":"100-105","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":68,"special_numbering":"C","title":["Dopamine D2\/D3 but not dopamine D1 receptors are involved in the rapid antidepressant-like effects of ketamine in the forced swim test"],"prefix":"10.1016","volume":"279","author":[{"given":"Yan","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuo R.","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bao C.","family":"Ou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya Q.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhou B.","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang M.","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi Y.","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji H.","family":"So","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang L.","family":"Mu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan Q.","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbr.2014.11.016_bib0005","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.bbr.2013.07.032","article-title":"The activation of adenosine monophosphate-activated protein kinase in rat hippocampus contributes to the rapid antidepressant effect of ketamine","volume":"253","author":"Xu","year":"2013","journal-title":"Behav Brain Res"},{"issue":"Suppl. 6","key":"10.1016\/j.bbr.2014.11.016_bib0010","first-page":"27","article-title":"Major depressive disorder: remission of associated symptoms","volume":"67","author":"Trivedi","year":"2006","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.bbr.2014.11.016_bib0015","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1056\/NEJMoa052964","article-title":"Medication augmentation after the failure of SSRIs for depression","volume":"354","author":"Trivedi","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.bbr.2014.11.016_bib0020","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1001\/archpsyc.63.8.856","article-title":"A randomized trial of an N-methyl-d-aspartate antagonist in treatment-resistant major depression","volume":"63","author":"Zarate","year":"2006","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.bbr.2014.11.016_bib0025","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.biopsych.2009.04.029","article-title":"Effects of intravenous ketamine on explicit and implicit measures of suicidality in treatment-resistant depression","volume":"66","author":"Price","year":"2009","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.bbr.2014.11.016_bib0030","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1001\/archgenpsychiatry.2010.90","article-title":"A randomized add-on trial of an N-methyl-d-aspartate antagonist in treatment-resistant bipolar depression","volume":"67","author":"Diazgranados","year":"2010","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.bbr.2014.11.016_bib0035","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1089\/jpm.2009.0312","article-title":"Treatment of resistant depression in patients with cancer with low doses of ketamine and desipramine","volume":"13","author":"Thangathurai","year":"2010","journal-title":"J Palliat Med"},{"key":"10.1016\/j.bbr.2014.11.016_bib0040","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.euroneuro.2005.12.002","article-title":"Dopaminergic-based pharmacotherapies for depression","volume":"16","author":"Papakostas","year":"2006","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.bbr.2014.11.016_bib0045","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.jad.2004.12.010","article-title":"Dopaminergic mechanism of antidepressant action in depressed patients","volume":"86","author":"Willner","year":"2005","journal-title":"J Affect Disord"},{"key":"10.1016\/j.bbr.2014.11.016_bib0050","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1176\/jnp.17.2.214","article-title":"Anhedonia, depression, and motor functioning in Parkinson's disease during treatment with pramipexole","volume":"17","author":"Lemke","year":"2005","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"10.1016\/j.bbr.2014.11.016_bib0055","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0079-6123(08)00913-8","article-title":"Dynamics of the dopaminergic system as a key component to the understanding of depression","volume":"172","author":"Yadid","year":"2008","journal-title":"Prog Brain Res"},{"key":"10.1016\/j.bbr.2014.11.016_bib0060","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/nature11740","article-title":"Dopamine neurons modulate neural encoding and expression of depression-related behaviour","volume":"493","author":"Tye","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.bbr.2014.11.016_bib0065","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1038\/nature11713","article-title":"Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons","volume":"493","author":"Chaudhury","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.bbr.2014.11.016_bib0070","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0014-2999(00)00566-5","article-title":"The role of dopamine in the mechanism of action of antidepressant drugs","volume":"405","author":"D\u2019Aquila","year":"2000","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.bbr.2014.11.016_bib0075","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0925-4927(99)00009-8","article-title":"Dopamine D2 receptor binding before and after treatment of major depression measured by [123I]IBZM SPECT","volume":"90","author":"Klimke","year":"1999","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.bbr.2014.11.016_bib0080","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/0014-2999(94)90033-7","article-title":"Antidepressant-like effect of selective dopamine D1 receptor agonists in the behavioural despair animal model of depression","volume":"262","author":"D\u2019Aquila","year":"1994","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.bbr.2014.11.016_bib0085","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.euroneuro.2005.02.003","article-title":"Antidepressant-like effects of selegiline in the forced swim test","volume":"15","author":"Shimazu","year":"2005","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.bbr.2014.11.016_bib0090","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0014-2999(88)90107-0","article-title":"Stimulation of dopamine D-2 but not D-1 receptors reduces immobility time of rats in the forced swimming test: implication for antidepressant activity","volume":"148","author":"Borsini","year":"1988","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.bbr.2014.11.016_bib0095","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0091-3057(95)02131-0","article-title":"Indirect dopamine agonists effects on despair test: dissociation from hyperactivity","volume":"54","author":"Vaugeois","year":"1996","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.bbr.2014.11.016_bib0100","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.ejphar.2004.09.057","article-title":"Involvement of dopamine receptors in the anti-immobility effects of dopamine re-uptake inhibitors in the forced swimming test","volume":"504","author":"Yamada","year":"2004","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.bbr.2014.11.016_bib0105","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/BF02253532","article-title":"Effects of dopamine D1 and D2 receptor blockade on MK-801-induced hyperlocomotion in rats","volume":"111","author":"Ouagazzal","year":"1993","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.bbr.2014.11.016_bib0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0014-2999(93)90085-V","article-title":"NMDA receptor antagonists inhibit catalepsy induced by either dopamine D1 or D2 receptor antagonists","volume":"237","author":"Moore","year":"1993","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.bbr.2014.11.016_bib0115","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0006-8993(97)00255-2","article-title":"Differential effects of single and repeated ketamine administration on dopamine, serotonin and GABA transmission in rat medial prefrontal cortex","volume":"759","author":"Lindefors","year":"1997","journal-title":"Brain Res"},{"key":"10.1016\/j.bbr.2014.11.016_bib0120","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1523\/JNEUROSCI.17-08-02921.1997","article-title":"Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex","volume":"17","author":"Moghaddam","year":"1997","journal-title":"J Neurosci"},{"key":"10.1016\/j.bbr.2014.11.016_bib0125","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.neuropharm.2010.10.009","article-title":"Increased binding of cortical and hippocampal group II metabotropic glutamate receptors in isolation-reared mice","volume":"60","author":"Kawasaki","year":"2011","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.bbr.2014.11.016_bib0130","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1097\/00008877-199711000-00010","article-title":"The forced swimming test as a model for core and component behavioral effects of antidepressant drugs","volume":"8","author":"Lucki","year":"1997","journal-title":"Behav Pharmacol"},{"key":"10.1016\/j.bbr.2014.11.016_bib0135","doi-asserted-by":"crossref","first-page":"e56053","DOI":"10.1371\/journal.pone.0056053","article-title":"Long-lasting antidepressant action of ketamine, but not glycogen synthase kinase-3 inhibitor SB216763, in the chronic mild stress model of mice","volume":"8","author":"Ma","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.bbr.2014.11.016_bib0140","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/nature10130","article-title":"NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses","volume":"475","author":"Autry","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.bbr.2014.11.016_bib0145","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1037\/1064-1297.5.2.107","article-title":"Acute and chronic antidepressant drug treatment in the rat forced swimming test model of depression","volume":"5","author":"Detke","year":"1997","journal-title":"Exp Clin Psychopharmacol"},{"issue":"Suppl. 4","key":"10.1016\/j.bbr.2014.11.016_bib0150","article-title":"Dopaminergic deficit and mood disorders","volume":"17","author":"Pania","year":"2002","journal-title":"Int Clin Psychopharmacol"},{"key":"10.1016\/j.bbr.2014.11.016_bib0155","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1517\/13543784.12.4.531","article-title":"New approaches to developing antidepressants by enhancing monoaminergic neurotransmission","volume":"12","author":"Bymaster","year":"2003","journal-title":"Expert Opin Investig Drugs"},{"key":"10.1016\/j.bbr.2014.11.016_bib0160","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1007\/s002130050791","article-title":"Effect of antidepressant drugs on dopamine D1 and D2 receptor expression and dopamine release in the nucleus accumbens of the rat","volume":"140","author":"Ainsworth","year":"1998","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.bbr.2014.11.016_bib0165","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1038\/sj.mp.4000756","article-title":"Dopamine D3 receptor gene expression in the shell of nucleus accumbens is increased by chronic antidepressant treatment","volume":"5","author":"Lammers","year":"2000","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.bbr.2014.11.016_bib0170","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1177\/026988119801200304","article-title":"Repeated administration of fluoxetine, desipramine and tranylcypromine increases dopamine D2-like but not D1-like receptor function in the rat","volume":"12","author":"Ainsworth","year":"1998","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.bbr.2014.11.016_bib0175","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0014-2999(97)01412-X","article-title":"Anti-anhedonic actions of the novel serotonergic agent flibanserin, a potential rapidly-acting antidepressant","volume":"340","author":"D\u2019Aquila","year":"1997","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.bbr.2014.11.016_bib0180","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0091-3057(94)90495-2","article-title":"Involvement of dopamine D2 receptor mechanism in the REM sleep deprivation-induced increase in swimming activity in the forced swimming test","volume":"48","author":"Asakura","year":"1994","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.bbr.2014.11.016_bib0185","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/FBP.0b013e32833470a7","article-title":"Dopamine is involved in the antidepressant-like effect of allopregnanolone in the forced swimming test in female rats","volume":"21","author":"D\u2019Aquila","year":"2010","journal-title":"Behav Pharmacol"},{"key":"10.1016\/j.bbr.2014.11.016_bib0190","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0014-2999(92)90029-4","article-title":"The behavioural effects of MK-801 in rats: involvement of dopaminergic, serotonergic and noradrenergic systems","volume":"215","author":"Loscher","year":"1992","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.bbr.2014.11.016_bib0195","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/BF01250962","article-title":"MK-801 induced stereotypies in rats are decreased by haloperidol and increased by diazepam","volume":"90","author":"Behrens","year":"1992","journal-title":"J Neural Transm Gen Sect"},{"key":"10.1016\/j.bbr.2014.11.016_bib0200","first-page":"337","article-title":"The effect of CGP 37849 and CGP 39551, competitive NMDA receptor antagonists, in the forced swimming test","volume":"44","author":"Maj","year":"1992","journal-title":"Pol J Pharmacol Pharm"},{"key":"10.1016\/j.bbr.2014.11.016_bib0205","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1111\/j.1472-8206.2004.00287.x","article-title":"Dopamine, depression and antidepressants","volume":"18","author":"Dailly","year":"2004","journal-title":"Fundam Clin Pharmacol"},{"key":"10.1016\/j.bbr.2014.11.016_bib0210","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0306-4522(96)00444-7","article-title":"A subset of ventral tegmental area neurons is inhibited by dopamine, 5-hydroxytryptamine and opioids","volume":"77","author":"Cameron","year":"1997","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbr.2014.11.016_bib0215","doi-asserted-by":"crossref","first-page":"5173","DOI":"10.1523\/JNEUROSCI.22-12-05173.2002","article-title":"Activation of ventral tegmental area cells by the bed nucleus of the stria terminalis: a novel excitatory amino acid input to midbrain dopamine neurons","volume":"22","author":"Georges","year":"2002","journal-title":"J Neurosci"},{"key":"10.1016\/j.bbr.2014.11.016_bib0220","doi-asserted-by":"crossref","first-page":"5167","DOI":"10.1073\/pnas.0510715103","article-title":"The laterodorsal tegmentum is essential for burst firing of ventral tegmental area dopamine neurons","volume":"103","author":"Lodge","year":"2006","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["Behavioural Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432814007451?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432814007451?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,17]],"date-time":"2019-08-17T09:53:31Z","timestamp":1566035611000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166432814007451"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":44,"alternative-id":["S0166432814007451"],"URL":"https:\/\/doi.org\/10.1016\/j.bbr.2014.11.016","relation":{},"ISSN":["0166-4328"],"issn-type":[{"value":"0166-4328","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dopamine D2\/D3 but not dopamine D1 receptors are involved in the rapid antidepressant-like effects of ketamine in the forced swim test","name":"articletitle","label":"Article Title"},{"value":"Behavioural Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbr.2014.11.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}