{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T22:30:56Z","timestamp":1759617056215},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Behavioural Brain Research"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1016\/j.bbr.2017.06.036","type":"journal-article","created":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T07:45:14Z","timestamp":1498117514000},"page":"27-34","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Hypoxic postconditioning improves behavioural deficits at 6 weeks following hypoxic-ischemic brain injury in neonatal rats"],"prefix":"10.1016","volume":"333","author":[{"given":"Jonathan D.","family":"Teo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret J.","family":"Morris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole M.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"9814","key":"10.1016\/j.bbr.2017.06.036_bib0005","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0140-6736(11)61577-8","article-title":"Long-term neurodevelopmental outcomes after intrauterine and neonatal insults: a systematic review","volume":"379","author":"Mwaniki","year":"2012","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.bbr.2017.06.036_bib0010","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.jpeds.2013.02.003","article-title":"Long-term neurodevelopmental outcome with hypoxic-ischemic encephalopathy","volume":"163","author":"Perez","year":"2013","journal-title":"J. Pediatr."},{"issue":"2","key":"10.1016\/j.bbr.2017.06.036_bib0015","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.bbr.2010.01.007","article-title":"Long-term losses of amygdala corticotropin-releasing factor neurons are associated with behavioural outcomes following neonatal hypoxia-ischemia","volume":"208","author":"Carty","year":"2010","journal-title":"Behav. Brain Res."},{"issue":"5","key":"10.1016\/j.bbr.2017.06.036_bib0020","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1203\/00006450-199711000-00021","article-title":"Sensorimotor function and neuropathology five to six weeks after hypoxia-ischemia in seven-day-old rats","volume":"42","author":"Bona","year":"1997","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.bbr.2017.06.036_bib0025","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.expneurol.2015.08.017","article-title":"Neonatal hypoxia-ischemia impairs juvenile recognition memory by disrupting the maturation of prefrontal-hippocampal networks","volume":"273","author":"Domnick","year":"2015","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bbr.2017.06.036_bib0030","article-title":"Cooling for newborns with hypoxic ischaemic encephalopathy","volume":"1","author":"Jacobs","year":"2013","journal-title":"Cochrane Database Syst. Rev."},{"issue":"3","key":"10.1016\/j.bbr.2017.06.036_bib0035","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1203\/00006450-200203000-00015","article-title":"Delayed postischemic hypothermia improves long-term behavioral outcome after cerebral hypoxia-ischemia in neonatal rats","volume":"51","author":"Wagner","year":"2002","journal-title":"Pediatr. Res."},{"issue":"3","key":"10.1016\/j.bbr.2017.06.036_bib0040","doi-asserted-by":"crossref","first-page":"e624","DOI":"10.1542\/peds.2014-1566","article-title":"Cognitive outcomes after neonatal encephalopathy","volume":"135","author":"Pappas","year":"2015","journal-title":"Pediatrics"},{"issue":"1","key":"10.1016\/j.bbr.2017.06.036_bib0045","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.bbr.2012.01.054","article-title":"Repeated mild hypoxic exposures decrease anxiety-like behavior in the adult mouse together with an increased brain adrenomedullin gene expression","volume":"230","author":"Leconte","year":"2012","journal-title":"Behav. Brain Res."},{"issue":"6","key":"10.1016\/j.bbr.2017.06.036_bib0050","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1203\/PDR.0b013e31816d9117","article-title":"Long-term functional and protective actions of preconditioning with hypoxia: cobalt chloride, and desferrioxamine against hypoxic-ischemic injury in neonatal rats","volume":"63","author":"Jones","year":"2008","journal-title":"Pediatr. Res."},{"issue":"6","key":"10.1016\/j.bbr.2017.06.036_bib0055","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1159\/000121368","article-title":"Hypoxic preconditioning improves spatial cognitive ability in mice","volume":"15","author":"Shao","year":"2006","journal-title":"Neurosignals"},{"issue":"6","key":"10.1016\/j.bbr.2017.06.036_bib0060","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1038\/pr.2015.47","article-title":"Hypoxic postconditioning reduces microglial activation: astrocyte and caspase activity, and inflammatory markers after hypoxia-ischemia in the neonatal rat brain","volume":"77","author":"Teo","year":"2015","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.bbr.2017.06.036_bib0065","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2012.12.026","article-title":"The neuroprotective actions of hypoxic preconditioning and postconditioning in a neonatal rat model of hypoxic-ischemic brain injury","volume":"1498","author":"Galle","year":"2013","journal-title":"Brain Res."},{"issue":"3","key":"10.1016\/j.bbr.2017.06.036_bib0070","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1007\/s12035-013-8611-7","article-title":"The roles of p38 MAPK\/MSK1 signaling pathway in the neuroprotection of hypoxic postconditioning against transient global cerebral ischemia in adult rats","volume":"49","author":"Zhu","year":"2014","journal-title":"Mol. Neurobiol."},{"issue":"10","key":"10.1016\/j.bbr.2017.06.036_bib0075","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1097\/NEN.0000000000000118","article-title":"Hypoxia-inducible factor 1alpha mediates neuroprotection of hypoxic postconditioning against global cerebral ischemia","volume":"73","author":"Zhu","year":"2014","journal-title":"J. Neuropathol. Exp. Neurol."},{"issue":"5","key":"10.1016\/j.bbr.2017.06.036_bib0080","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.neuropharm.2012.06.035","article-title":"Activation of Akt\/FoxO and inactivation of MEK\/ERK pathways contribute to induction of neuroprotection against transient global cerebral ischemia by delayed hypoxic postconditioning in adult rats","volume":"63","author":"Zhan","year":"2012","journal-title":"Neuropharmacology"},{"issue":"2","key":"10.1016\/j.bbr.2017.06.036_bib0085","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0892-0362(92)90060-N","article-title":"Behavioral sequelae in young rats of acute intermittent antenatal hypoxia","volume":"14","author":"Hermans","year":"1992","journal-title":"Neurotoxicol. Teratol."},{"issue":"3","key":"10.1016\/j.bbr.2017.06.036_bib0090","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1038\/nprot.2006.205","article-title":"Object recognition in rats and mice: a one-trial non-matching-to-sample learning task to study \u2018recognition memory'","volume":"1","author":"Bevins","year":"2006","journal-title":"Nat Protoc"},{"issue":"2","key":"10.1016\/j.bbr.2017.06.036_bib0095","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1161\/01.STR.18.2.503","article-title":"Motor performance in rats exposed to severe forebrain ischemia: effect of fasting and 1,3-butanediol","volume":"18","author":"Combs","year":"1987","journal-title":"Stroke"},{"issue":"9","key":"10.1016\/j.bbr.2017.06.036_bib0100","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1097\/00004647-200109000-00008","article-title":"Hypoxic preconditioning induces changes in HIF-1 target genes in neonatal rat brain","volume":"21","author":"Jones","year":"2001","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"2","key":"10.1016\/j.bbr.2017.06.036_bib0105","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/ana.410090206","article-title":"The influence of immaturity on hypoxic-ischemic brain damage in the rat","volume":"9","author":"Rice","year":"1981","journal-title":"Ann. Neurol."},{"issue":"2","key":"10.1016\/j.bbr.2017.06.036_bib0110","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0166-4328(95)00248-0","article-title":"Long-term effects of neonatal ischemic-hypoxic brain injury on sensorimotor and locomotor tasks in rats","volume":"78","author":"Jansen","year":"1996","journal-title":"Behav. Brain Res."},{"issue":"1","key":"10.1016\/j.bbr.2017.06.036_bib0115","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.bbr.2004.06.019","article-title":"Neurological reflexes and early motor behavior in rats subjected to neonatal hypoxic\u2013ischemic injury","volume":"157","author":"Lubics","year":"2005","journal-title":"Behav. Brain Res."},{"issue":"1-2","key":"10.1016\/j.bbr.2017.06.036_bib0120","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0166-4328(03)00146-3","article-title":"Brain injury and neurofunctional deficit in neonatal mice with hypoxic-ischemic encephalopathy","volume":"145","author":"Ten","year":"2003","journal-title":"Behav. Brain Res."},{"issue":"2","key":"10.1016\/j.bbr.2017.06.036_bib0125","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/S0006-8993(00)01997-1","article-title":"Long-lasting behavioral alterations following a hypoxic\/ischemic brain injury in neonatal rats","volume":"859","author":"Balduini","year":"2000","journal-title":"Brain Res."},{"issue":"2","key":"10.1016\/j.bbr.2017.06.036_bib0130","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0006-8993(03)02436-3","article-title":"Neonatal cerebral hypoxia-ischemia causes lateralized memory impairments in the adult rat","volume":"973","author":"Arteni","year":"2003","journal-title":"Brain Res."},{"issue":"4","key":"10.1016\/j.bbr.2017.06.036_bib0135","first-page":"265","article-title":"Brain plasticity and behaviour in the developing brain","volume":"20","author":"Kolb","year":"2011","journal-title":"J. Canad. Acad. Child Adoles. Psych."},{"key":"10.1016\/j.bbr.2017.06.036_bib0140","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/B978-0-444-53884-0.00022-1","article-title":"Perinatal brain damage in children: neuroplasticity, early intervention, and molecular mechanisms of recovery","volume":"189","author":"Cioni","year":"2011","journal-title":"Prog. Brain Res."},{"issue":"10","key":"10.1016\/j.bbr.2017.06.036_bib0145","doi-asserted-by":"crossref","first-page":"3449","DOI":"10.1523\/JNEUROSCI.10-10-03449.1990","article-title":"The recovery of forelimb-placing behavior in rats with neonatal unilateral cortical damage involves the remaining hemisphere","volume":"10","author":"Barth","year":"1990","journal-title":"J. Neurosci."},{"issue":"5","key":"10.1016\/j.bbr.2017.06.036_bib0150","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/0031-9384(95)00103-P","article-title":"Locomotor and passive avoidance deficits following occlusion of the middle cerebral artery","volume":"58","author":"Borlongan","year":"1995","journal-title":"Physiol. Behav."},{"issue":"10","key":"10.1016\/j.bbr.2017.06.036_bib0155","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1097\/00004647-199810000-00006","article-title":"Evaluation of a motor deficit after chronic focal cerebral ischemia in rats","volume":"18","author":"Yonemori","year":"1998","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"1-2","key":"10.1016\/j.bbr.2017.06.036_bib0160","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/0006-8993(88)90036-4","article-title":"Behavioral changes after focal cerebral ischemia by left middle cerebral artery occlusion in rats","volume":"452","author":"Yamamoto","year":"1988","journal-title":"Brain Res."},{"issue":"2","key":"10.1016\/j.bbr.2017.06.036_bib0165","doi-asserted-by":"crossref","first-page":"e90258","DOI":"10.1371\/journal.pone.0090258","article-title":"Delayed remote ischemic postconditioning improves long term sensory motor deficits in a neonatal hypoxic ischemic rat model","volume":"9","author":"Drunalini Perera","year":"2014","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.bbr.2017.06.036_bib0170","doi-asserted-by":"crossref","first-page":"2060","DOI":"10.1161\/01.STR.28.10.2060","article-title":"Correlation between motor impairment and infarct volume after permanent and transient middle cerebral artery occlusion in the rat","volume":"28","author":"Rogers","year":"1997","journal-title":"Stroke"},{"issue":"1","key":"10.1016\/j.bbr.2017.06.036_bib0175","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.brainres.2006.08.030","article-title":"Adult neurological function following neonatal hypoxia-ischemia in a mouse model of the term neonate: water maze performance is dependent on separable cognitive and motor components","volume":"1118","author":"McAuliffe","year":"2006","journal-title":"Brain Res."},{"issue":"3","key":"10.1016\/j.bbr.2017.06.036_bib0180","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1038\/pr.2015.100","article-title":"Therapeutic hypothermia and hypoxia-ischemia in the term-equivalent neonatal rat: characterization of a translational preclinical model","volume":"78","author":"Patel","year":"2015","journal-title":"Pediatr. Res."},{"issue":"1","key":"10.1016\/j.bbr.2017.06.036_bib0185","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0166-4328(00)00287-4","article-title":"Selective and long-term learning impairment following neonatal hypoxic-ischemic brain insult in rats","volume":"118","author":"Ikeda","year":"2001","journal-title":"Behav. Brain Res."},{"issue":"3","key":"10.1016\/j.bbr.2017.06.036_bib0190","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1038\/jcbfm.1995.62","article-title":"Long-term spatial cognitive impairment following middle cerebral artery occlusion in rats: a behavioral study","volume":"15","author":"Okada","year":"1995","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"8","key":"10.1016\/j.bbr.2017.06.036_bib0195","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1038\/nn.3154","article-title":"Memory signals are temporally dissociated in and across human hippocampus and perirhinal cortex","volume":"15","author":"Staresina","year":"2012","journal-title":"Nat. Neurosci."},{"issue":"13","key":"10.1016\/j.bbr.2017.06.036_bib0200","doi-asserted-by":"crossref","first-page":"4473","DOI":"10.1523\/JNEUROSCI.5751-11.2012","article-title":"A role for perirhinal cortex in memory for novel object-context associations","volume":"32","author":"Watson","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbr.2017.06.036_bib0205","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.brainres.2008.04.010","article-title":"Early enriched housing results in partial recovery of memory deficits in female, but not in male, rats after neonatal hypoxia-ischemia","volume":"1218","author":"Pereira","year":"2008","journal-title":"Brain Res."},{"issue":"5","key":"10.1016\/j.bbr.2017.06.036_bib0210","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.neuropharm.2012.05.034","article-title":"Cannabidiol administration after hypoxia-ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function","volume":"63","author":"Pazos","year":"2012","journal-title":"Neuropharmacology"},{"issue":"2","key":"10.1016\/j.bbr.2017.06.036_bib0215","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1203\/01.PDR.0000151122.58665.70","article-title":"Hypoxic preconditioning confers long-term reduction of brain injury and improvement of neurological ability in immature rats","volume":"57","author":"Gustavsson","year":"2005","journal-title":"Pediatr. Res."},{"issue":"2","key":"10.1016\/j.bbr.2017.06.036_bib0220","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1161\/STROKEAHA.110.592162","article-title":"Remote limb ischemic postconditioning protects against neonatal hypoxic-ischemic brain injury in rat pups by the opioid receptor\/Akt pathway","volume":"42","author":"Zhou","year":"2011","journal-title":"Stroke"},{"issue":"1","key":"10.1016\/j.bbr.2017.06.036_bib0225","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.neulet.2012.02.019","article-title":"Postconditioning by mild hypoxic exposures reduces rat brain injury caused by severe hypoxia","volume":"513","author":"Rybnikova","year":"2012","journal-title":"Neurosci. Lett."},{"issue":"10","key":"10.1016\/j.bbr.2017.06.036_bib0230","doi-asserted-by":"crossref","first-page":"3349","DOI":"10.1161\/STROKEAHA.109.557314","article-title":"Delayed hypoxic postconditioning protects against cerebral ischemia in the mouse","volume":"40","author":"Leconte","year":"2009","journal-title":"Stroke"},{"issue":"1","key":"10.1016\/j.bbr.2017.06.036_bib0235","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1053\/siny.1999.0112","article-title":"Mechanisms of perinatal brain injury","volume":"5","author":"Inder","year":"2000","journal-title":"Semin. Neonatol."},{"issue":"7","key":"10.1016\/j.bbr.2017.06.036_bib0240","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1093\/abbs\/gmv043","article-title":"Up-regulation of iNOS by hypoxic postconditioning inhibits H9c2 cardiomyocyte apoptosis induced by hypoxia\/re-oxygenation","volume":"47","author":"Zhao","year":"2015","journal-title":"Acta Biochim Biophys Sin (Shanghai)"},{"issue":"8","key":"10.1016\/j.bbr.2017.06.036_bib0245","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1007\/s10495-015-1127-z","article-title":"PUMA-mediated mitochondrial apoptotic disruption by hypoxic postconditioning","volume":"20","author":"Li","year":"2015","journal-title":"Apoptosis"},{"key":"10.1016\/j.bbr.2017.06.036_bib0250","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.neuroscience.2014.08.019","article-title":"Pharmacologic stabilization of hypoxia-inducible transcription factors protects developing mouse brain from hypoxia-induced apoptotic cell death","volume":"278","author":"Trollmann","year":"2014","journal-title":"Neuroscience"},{"issue":"10","key":"10.1016\/j.bbr.2017.06.036_bib0255","doi-asserted-by":"crossref","first-page":"e0140035","DOI":"10.1371\/journal.pone.0140035","article-title":"Reduced cerebral oxygen content in the DG and SVZ in situ promotes neurogenesis in the adult rat brain in vivo","volume":"10","author":"Zhang","year":"2015","journal-title":"PLoS One"},{"issue":"1-2","key":"10.1016\/j.bbr.2017.06.036_bib0260","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.neulet.2006.05.049","article-title":"Hypoxic preconditioning produces differential expression of hypoxia-inducible factor-1alpha (HIF-1alpha) and its regulatory enzyme HIF prolyl hydroxylase 2 in neonatal rat brain","volume":"404","author":"Jones","year":"2006","journal-title":"Neurosci. Lett."},{"issue":"1","key":"10.1016\/j.bbr.2017.06.036_bib0265","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/pr.2014.53","article-title":"Hypoxic preconditioning protection is eliminated in HIF-1alpha knockout mice subjected to neonatal hypoxia-ischemia","volume":"76","author":"Sheldon","year":"2014","journal-title":"Pediatr. Res."}],"container-title":["Behavioural Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432817301341?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432817301341?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,6,28]],"date-time":"2018-06-28T03:00:53Z","timestamp":1530154853000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166432817301341"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":53,"alternative-id":["S0166432817301341"],"URL":"https:\/\/doi.org\/10.1016\/j.bbr.2017.06.036","relation":{},"ISSN":["0166-4328"],"issn-type":[{"value":"0166-4328","type":"print"}],"subject":[],"published":{"date-parts":[[2017,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypoxic postconditioning improves behavioural deficits at 6 weeks following hypoxic-ischemic brain injury in neonatal rats","name":"articletitle","label":"Article Title"},{"value":"Behavioural Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbr.2017.06.036","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}