{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T09:27:23Z","timestamp":1769160443161,"version":"3.49.0"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["91432108"],"award-info":[{"award-number":["91432108"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Behavioural Brain Research"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1016\/j.bbr.2018.11.044","type":"journal-article","created":{"date-parts":[[2018,11,30]],"date-time":"2018-11-30T11:53:30Z","timestamp":1543578810000},"page":"60-68","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Preliminary validation of natural depression in macaques with acute treatments of the fast-acting antidepressant ketamine"],"prefix":"10.1016","volume":"360","author":[{"given":"Xunxun","family":"Chu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbr.2018.11.044_bib0005","series-title":"Depression and Other Mental Disorders: Global Health Estimates, Licence: CC BY-NC-SA 3.0 IGO","author":"WHO","year":"2017"},{"issue":"7493","key":"10.1016\/j.bbr.2018.11.044_bib0010","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1038\/507423a","article-title":"Make mouse studies work","volume":"507","author":"Perrin","year":"2014","journal-title":"Nature"},{"issue":"9","key":"10.1016\/j.bbr.2018.11.044_bib0015","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1002\/ajp.22281","article-title":"Why primate models matter","volume":"76","author":"Phillips","year":"2014","journal-title":"Am. J. Primatol."},{"issue":"3","key":"10.1016\/j.bbr.2018.11.044_bib0020","first-page":"174","article-title":"A natural model of behavioral depression in postpartum adult female cynomolgus monkeys (Macaca fascicularis)","volume":"35","author":"Chu","year":"2014","journal-title":"Zool. Res."},{"key":"10.1016\/j.bbr.2018.11.044_bib0025","doi-asserted-by":"crossref","first-page":"11267","DOI":"10.1038\/srep11267","article-title":"A spontaneous depressive pattern in adult female rhesus macaques","volume":"5","author":"Qin","year":"2015","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.bbr.2018.11.044_bib0030","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1037\/h0092706","article-title":"Introduction to the special section: ecological momentary assessment in health psychology","volume":"17","author":"Shiffman","year":"1998","journal-title":"Health Psychol."},{"key":"10.1016\/j.bbr.2018.11.044_bib0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00427414","article-title":"The validity of animal models of depression","volume":"83","author":"Willner","year":"1984","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.bbr.2018.11.044_bib0040","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jad.2013.11.014","article-title":"A review of ketamine in affective disorders: current evidence of clinical efficacy, limitations of use and pre-clinical evidence on proposed mechanisms of action","volume":"156","author":"Naughton","year":"2014","journal-title":"J. Affect. Disord."},{"issue":"3","key":"10.1016\/j.bbr.2018.11.044_bib0045","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.pnpbp.2003.11.018","article-title":"Central monoamines and their role in major depression","volume":"28","author":"Elhwuegi","year":"2004","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.bbr.2018.11.044_bib0050","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/da.1043","article-title":"Depression, sleep physiology, and antidepressant drugs","volume":"14","author":"Winokur","year":"2001","journal-title":"Depress. Anxiety"},{"issue":"3","key":"10.1016\/j.bbr.2018.11.044_bib0055","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/S0013-4694(97)00152-1","article-title":"Scoring of sleep and wakefulness by behavioral analysis from video recordings in rhesus monkeys\uff1acomparison with conventional EEG analysis","volume":"106","author":"Balzamo","year":"1998","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"10.1016\/j.bbr.2018.11.044_bib0060","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/j.1600-0773.1984.tb01966.x","article-title":"Liquid chromatograpgic assay for CSF catecholamines using electrochemical detection","volume":"55","author":"Seppala","year":"1984","journal-title":"Acta Pharmacol. Toxicol."},{"issue":"1","key":"10.1016\/j.bbr.2018.11.044_bib0065","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/0003-2697(83)90162-8","article-title":"Stimultaneous determinationof 3-methoxy-4-hydroxyphenylglycol, 5-hydroxyindoleacetic acid, and homovanillic acid in cerebrospinal fluid with high-performance liquid chromatography using electrochemical detection","volume":"131","author":"Scheinin","year":"1983","journal-title":"Anal. Biochem."},{"issue":"1","key":"10.1016\/j.bbr.2018.11.044_bib0070","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.biopsycho.2004.11.006","article-title":"Social stress-associated depression in adult female cynomolgus monkeys (Macaca fascicularis)","volume":"69","author":"Shively","year":"2005","journal-title":"Biol. Psychol."},{"issue":"5","key":"10.1016\/j.bbr.2018.11.044_bib0075","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/j.cell.2017.04.035","article-title":"Modeling Rett Syndrome Using TALEN-Edited MECP2 Mutant Cynomolgus Monkeys","volume":"169","author":"Chen","year":"2017","journal-title":"Cell"},{"issue":"1-2","key":"10.1016\/j.bbr.2018.11.044_bib0080","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0166-4328(03)00111-6","article-title":"Sleep and social status in captive gelada baboons (Theropithecus gelada)","volume":"147","author":"Noser","year":"2003","journal-title":"Behav. Brain Res."},{"issue":"13","key":"10.1016\/j.bbr.2018.11.044_bib0085","doi-asserted-by":"crossref","first-page":"2666","DOI":"10.1038\/npp.2013.176","article-title":"Subanesthetic doses of ketamine transiently decrease serotonin transporter activity: a PET study in conscious monkeys","volume":"38","author":"Yamamoto","year":"2013","journal-title":"Neuropsychopharmacology"},{"issue":"5722","key":"10.1016\/j.bbr.2018.11.044_bib0090","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1126\/science.1106477","article-title":"The influence of social hierarchy on primate health","volume":"308","author":"Sapolsky","year":"2005","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.bbr.2018.11.044_bib0095","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1038\/87865","article-title":"The cellular neurobiology of depression","volume":"7","author":"Manji","year":"2001","journal-title":"Nat. Med."},{"issue":"2","key":"10.1016\/j.bbr.2018.11.044_bib0100","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1093\/ilar\/ilu030","article-title":"Nonhuman primate models of depression: effects of early experience and stress","volume":"55","author":"Worlein","year":"2014","journal-title":"ILAR J."},{"key":"10.1016\/j.bbr.2018.11.044_bib0105","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/S0006-3223(96)00185-0","article-title":"Behavior and physiology of social stress and depression in female Cynomolgus monkeys","volume":"41","author":"Shively","year":"1997","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbr.2018.11.044_bib0110","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1001\/archpsyc.63.4.396","article-title":"Behavioral depression and PET-determined 5-HT 1a receptor binding potential in cynomolgus monkeys","volume":"63","author":"Shively","year":"2006","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.bbr.2018.11.044_bib0115","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.bbr.2015.07.005","article-title":"The first observation of seasonal affective disorder symptoms in Rhesus macaque","volume":"292","author":"Qin","year":"2015","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.bbr.2018.11.044_bib0120","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1001\/archpsyc.1978.01770270071006","article-title":"Effects of imipramine treatment on sparation induced social disorders in Rhesus monkeys","volume":"35","author":"Suomi","year":"1978","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.bbr.2018.11.044_bib0125","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.neuroscience.2015.01.008","article-title":"Sex differences in the rapid and the sustained antidepressant-like effects of ketamine in stress-naive and \"depressed\" mice exposed to chronic mild stress","volume":"290","author":"Franceschelli","year":"2015","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbr.2018.11.044_bib0130","doi-asserted-by":"crossref","first-page":"9220","DOI":"10.1038\/srep09220","article-title":"Macaques exhibit a naturally-occurring depression similar to humans","volume":"5","author":"Xu","year":"2015","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.bbr.2018.11.044_bib0135","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.tins.2011.11.005","article-title":"The neurobiology of anhedonia and other reward-related deficits","volume":"35","author":"Der-Avakian","year":"2012","journal-title":"Trends Neurosci."},{"issue":"2","key":"10.1016\/j.bbr.2018.11.044_bib0140","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1017\/S1461145712000545","article-title":"Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder","volume":"16","author":"Duncan","year":"2013","journal-title":"Int. J. Neuropsychopharmacol."},{"issue":"4266","key":"10.1016\/j.bbr.2018.11.044_bib0145","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1126\/science.982039","article-title":"Sleep in mammals: ecological and constitutional correlates","volume":"194","author":"Allison","year":"1976","journal-title":"Science"},{"issue":"7","key":"10.1016\/j.bbr.2018.11.044_bib0150","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1586\/ern.10.83","article-title":"Sleep deprivation in depression","volume":"10","author":"Hemmeter","year":"2010","journal-title":"Expert Rev. Neurother."}],"container-title":["Behavioural Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016643281830980X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016643281830980X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,4]],"date-time":"2019-01-04T09:17:39Z","timestamp":1546593459000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016643281830980X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":30,"alternative-id":["S016643281830980X"],"URL":"https:\/\/doi.org\/10.1016\/j.bbr.2018.11.044","relation":{},"ISSN":["0166-4328"],"issn-type":[{"value":"0166-4328","type":"print"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Preliminary validation of natural depression in macaques with acute treatments of the fast-acting antidepressant ketamine","name":"articletitle","label":"Article Title"},{"value":"Behavioural Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbr.2018.11.044","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}