{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T13:40:03Z","timestamp":1759066803373,"version":"3.44.0"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003042","name":"Else Kr\u00f6ner-Fresenius-Stiftung","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003042","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Behavioural Brain Research"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.bbr.2019.111915","type":"journal-article","created":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T20:59:32Z","timestamp":1555361972000},"page":"111915","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Physical activity sustains memory retrieval in dopamine-depleted mice previously treated with L-Dopa"],"prefix":"10.1016","volume":"369","author":[{"given":"D","family":"Iggena","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Klein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Rasi\u0144ska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Sparenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y","family":"Winter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Steiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbr.2019.111915_bib0005","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/S1474-4422(16)30230-7","article-title":"The epidemiology of Parkinson\u2019s disease: risk factors and prevention","volume":"15","author":"Ascherio","year":"2016","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.bbr.2019.111915_bib0010","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S1474-4422(06)70471-9","article-title":"Epidemiology of Parkinson\u2019s disease","volume":"5","author":"de Lau","year":"2006","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.bbr.2019.111915_bib0015","doi-asserted-by":"crossref","first-page":"2286","DOI":"10.1002\/mds.23878","article-title":"Projected numbers of people with movement disorders in the years 2030 and 2050","volume":"26","author":"Bach","year":"2011","journal-title":"Mov. Disord."},{"key":"10.1016\/j.bbr.2019.111915_bib0020","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1002\/mds.25870","article-title":"Cognitive impairment and dementia in Parkinson\u2019s disease: practical issues and management","volume":"29","author":"Emre","year":"2014","journal-title":"Mov. Disord."},{"key":"10.1016\/j.bbr.2019.111915_bib0025","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s00415-009-5240-1","article-title":"Non-motor symptoms in Parkinson\u2019s disease","volume":"256","author":"Park","year":"2009","journal-title":"J. Neurol."},{"key":"10.1016\/j.bbr.2019.111915_bib0030","doi-asserted-by":"crossref","first-page":"659","DOI":"10.3233\/JPD-150604","article-title":"Neuropsychiatric Symptoms in Parkinson\u2019s Disease","volume":"5","author":"Aarsland","year":"2015","journal-title":"J. Parkinsons Dis."},{"key":"10.1016\/j.bbr.2019.111915_bib0035","first-page":"120","article-title":"Preferential loss of serotonin markers in caudate versus putamen in Parkinson\u2019s disease","volume":"131","author":"Kish","year":"2007","journal-title":"Brain."},{"key":"10.1016\/j.bbr.2019.111915_bib0040","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.pharmthera.2006.08.004","article-title":"Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission","volume":"113","author":"Alex","year":"2007","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.bbr.2019.111915_bib0045","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0079-6123(08)00912-6","article-title":"The dorsal raphe nucleus and serotonin: implications for neuroplasticity linked to major depression and Alzheimer\u2019s disease","volume":"172","author":"Michelsen","year":"2008","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.bbr.2019.111915_bib0050","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0146671","article-title":"Influences of chronic mild stress exposure on motor, non-motor impairments and neurochemical variables in specific brain areas of MPTP\/Probenecid induced neurotoxicity in mice","volume":"11","author":"Janakiraman","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.bbr.2019.111915_bib0055","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1002\/mds.26291","article-title":"Exercise improves cognition in Parkinson\u2019s disease: the PRET-PD randomized, clinical trial","volume":"30","author":"David","year":"2015","journal-title":"Mov. Disord."},{"key":"10.1016\/j.bbr.2019.111915_bib0060","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/S0306-4522(03)00096-4","article-title":"Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson\u2019s disease","volume":"119","author":"Tillerson","year":"2003","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbr.2019.111915_bib0065","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1159\/000137378","article-title":"Lifestyle and memory in the elderly","volume":"31","author":"Fl\u00f6el","year":"2008","journal-title":"Neuroepidemiology."},{"key":"10.1016\/j.bbr.2019.111915_bib0070","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1016\/j.neurobiolaging.2009.08.001","article-title":"Physical activity and memory functions: an interventional study","volume":"32","author":"Ruscheweyh","year":"2011","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.bbr.2019.111915_bib0075","first-page":"284","article-title":"Effects of treadmill training on cognitive and motor features of patients with mild to moderate Parkinson\u2019s disease: a pilot, single-blind, randomized controlled trial","volume":"5","author":"Picelli","year":"2016","journal-title":"Funct. Neurol."},{"key":"10.1016\/j.bbr.2019.111915_bib0080","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1007\/s00125-012-2677-z","article-title":"Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis","volume":"55","author":"Wilmot","year":"2012","journal-title":"Diabetologia."},{"key":"10.1016\/j.bbr.2019.111915_bib0085","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.amepre.2006.07.024","article-title":"Identifying sedentary subgroups: the national Cancer institute\u2019s health information national trends survey","volume":"31","author":"Atienza","year":"2006","journal-title":"Am. J. Prev. Med."},{"key":"10.1016\/j.bbr.2019.111915_bib0090","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S1474-4422(06)70471-9","article-title":"Epidemiology of Parkinson\u2019s disease","volume":"5","author":"de Lau","year":"2006","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.bbr.2019.111915_bib0095","doi-asserted-by":"crossref","first-page":"189","DOI":"10.3389\/fnins.2010.00189","article-title":"Why and How Physical Activity Promotes Experience-Induced Brain Plasticity","volume":"4","author":"Kempermann","year":"2010","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.bbr.2019.111915_bib0100","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1038\/nrn2822","article-title":"New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?","volume":"11","author":"Deng","year":"2010","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.bbr.2019.111915_bib0105","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/6368","article-title":"Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus","volume":"2","author":"van Praag","year":"1999","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbr.2019.111915_bib0110","doi-asserted-by":"crossref","first-page":"8680","DOI":"10.1523\/JNEUROSCI.1731-05.2005","article-title":"Exercise enhances learning and hippocampal neurogenesis in aged mice","volume":"25","author":"van Praag","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbr.2019.111915_bib0115","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.neuroscience.2004.10.009","article-title":"A role for adult neurogenesis in spatial long-term memory","volume":"130","author":"Snyder","year":"2005","journal-title":"Neuroscience."},{"key":"10.1016\/j.bbr.2019.111915_bib0120","doi-asserted-by":"crossref","first-page":"e1959","DOI":"10.1371\/journal.pone.0001959","article-title":"Spatial relational memory requires hippocampal adult neurogenesis","volume":"3","author":"Dupret","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.bbr.2019.111915_bib0125","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1002\/hipo.22520","article-title":"Mice in an enriched environment learn more flexibly because of adult hippocampal neurogenesis","volume":"26","author":"Garthe","year":"2016","journal-title":"Hippocampus."},{"key":"10.1016\/j.bbr.2019.111915_bib0130","doi-asserted-by":"crossref","first-page":"e5464","DOI":"10.1371\/journal.pone.0005464","article-title":"Adult-generated hippocampal neurons allow the flexible use of spatially precise learning strategies","volume":"4","author":"Garthe","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.bbr.2019.111915_bib0135","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1007\/s12640-015-9566-4","article-title":"Exercise improves cognitive impairment and dopamine metabolism in MPTP-Treated mice","volume":"29","author":"Aguiar","year":"2016","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.bbr.2019.111915_bib0140","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.bbr.2016.02.040","article-title":"Physical exercise counteracts MPTP-induced changes in neural precursor cell proliferation in the hippocampus and restores spatial learning but not memory performance in the water maze","volume":"307","author":"Klein","year":"2016","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.bbr.2019.111915_bib0145","doi-asserted-by":"crossref","first-page":"3203","DOI":"10.1589\/jpts.27.3203","article-title":"Effects of treadmill exercise on hippocampal neurogenesis in an MPTP \/probenecid-induced Parkinson\u2019s disease mouse model","volume":"27","author":"Sung","year":"2015","journal-title":"J. Phys. Ther. Sci."},{"key":"10.1016\/j.bbr.2019.111915_bib0150","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.brainres.2012.03.046","article-title":"MPTP-induced hippocampal effects on serotonin, dopamine, neurotrophins, adult neurogenesis and depression-like behavior are partially influenced by fluoxetine in adult mice","volume":"1457","author":"Lesemann","year":"2012","journal-title":"Brain Res."},{"key":"10.1016\/j.bbr.2019.111915_bib0155","doi-asserted-by":"crossref","first-page":"14141","DOI":"10.1038\/srep14141","article-title":"Only watching others making their experiences is insufficient to enhance adult neurogenesis and water maze performance in mice","volume":"5","author":"Iggena","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbr.2019.111915_bib0160","doi-asserted-by":"crossref","DOI":"10.1111\/jpi.12397","article-title":"Melatonin restores hippocampal neural precursor cell proliferation and prevents cognitive deficits induced by jet lag simulation in adult mice","volume":"62","author":"Iggena","year":"2017","journal-title":"J. Pineal Res."},{"year":"2003","series-title":"Paxinos and Franklin\u2019s the Mouse Brain in Stereotaxic Coordinates","author":"Franklin","key":"10.1016\/j.bbr.2019.111915_bib0165"},{"key":"10.1016\/j.bbr.2019.111915_bib0170","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbr.2019.111915_bib0175","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.nlm.2016.03.002","article-title":"Exercise prevents high-fat diet-induced impairment of flexible memory expression in the water maze and modulates adult hippocampal neurogenesis in mice","volume":"131","author":"Klein","year":"2016","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.bbr.2019.111915_bib0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0075125","article-title":"Hippocampal neurogenesis levels predict WATERMAZE search strategies in the aging brain","volume":"8","author":"Gil-Mohapel","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.bbr.2019.111915_bib0185","doi-asserted-by":"crossref","first-page":"3017","DOI":"10.1073\/pnas.1015950108","article-title":"Exercise training increases size of hippocampus and improves memory","volume":"108","author":"Erickson","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbr.2019.111915_bib0190","doi-asserted-by":"crossref","first-page":"13427","DOI":"10.1073\/pnas.96.23.13427","article-title":"Running enhances neurogenesis, learning, and long-term potentiation in mice","volume":"96","author":"van Praag","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbr.2019.111915_bib0195","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0050496","article-title":"Elevated homocysteine by levodopa is detrimental to neurogenesis in parkinsonian model","volume":"7","author":"Shin","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bbr.2019.111915_bib0200","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1002\/mds.22607","article-title":"Homocysteine levels after acute levodopa intake in patients with Parkinson\u2019s disease","volume":"24","author":"M\u00fcller","year":"2009","journal-title":"Mov. Disord."},{"key":"10.1016\/j.bbr.2019.111915_bib0205","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.jocn.2009.09.034","article-title":"L-Dopa therapy increases homocysteine concentration in cerebrospinal fluid from patients with Parkinson\u2019s disease","volume":"17","author":"Isobe","year":"2010","journal-title":"J. Clin. Neurosci."},{"key":"10.1016\/j.bbr.2019.111915_bib0210","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1002\/mds.22511","article-title":"Hyperhomocysteinemia in levodopa-treated patients with Parkinson\u2019s disease dementia","volume":"24","author":"Zoccolella","year":"2009","journal-title":"Mov. Disord."},{"key":"10.1016\/j.bbr.2019.111915_bib0215","first-page":"141","article-title":"Dopaminergic neuron-specific oxidative stress caused by dopamine itself","volume":"62","author":"Miyazaki","year":"2008","journal-title":"Acta Med. Okayama"},{"key":"10.1016\/j.bbr.2019.111915_bib0220","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1124\/pr.59.2.1","article-title":"Neurotoxicity and metabolism of the catecholamine-derived 3,4-Dihydroxyphenylacetaldehyde and 3,4-Dihydroxyphenylglycolaldehyde: the role of aldehyde dehydrogenase","volume":"59","author":"Marchitti","year":"2007","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.bbr.2019.111915_bib0225","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1111\/j.1460-9568.2004.03591.x","article-title":"Chronic l-DOPA treatment increases extracellular glutamate levels and GLT1 expression in the basal ganglia in a rat model of Parkinson\u2019s disease","volume":"20","author":"Robelet","year":"2004","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.bbr.2019.111915_bib0230","doi-asserted-by":"crossref","first-page":"469","DOI":"10.3389\/fnins.2015.00469","article-title":"Chronic Glutamate Toxicity in Neurodegenerative Diseases-What is the Evidence?","volume":"9","author":"Lewerenz","year":"2015","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.bbr.2019.111915_bib0235","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.brainres.2009.09.103","article-title":"Vertical grid test and modified horizontal grid test are sensitive methods for evaluating motor dysfunctions in the MPTP mouse model of Parkinson\u2019s disease","volume":"1306","author":"Kim","year":"2010","journal-title":"Brain Res."},{"key":"10.1016\/j.bbr.2019.111915_bib0240","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.neulet.2013.02.066","article-title":"The effect of dopamine on MPTP-induced rotarod disability","volume":"543","author":"Ayton","year":"2013","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.bbr.2019.111915_bib0245","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.bbr.2015.09.014","article-title":"MPTP-induced executive dysfunction is associated with altered prefrontal serotonergic function","volume":"298","author":"Maiti","year":"2016","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.bbr.2019.111915_bib0250","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1002\/jnr.23638","article-title":"Executive function deficits and glutamatergic protein alterations in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson\u2019s disease","volume":"93","author":"Pflibsen","year":"2015","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.bbr.2019.111915_bib0255","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/S0306-4522(98)00693-9","article-title":"Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats","volume":"89","author":"Brezun","year":"1999","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbr.2019.111915_bib0260","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1097\/00008877-199601000-00011","article-title":"In vivo measurement of extracellular serotonin in the ventral hippocampus during treadmill running","volume":"7","author":"Wilson","year":"1996","journal-title":"Behav. Pharmacol."},{"key":"10.1016\/j.bbr.2019.111915_bib0265","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.etp.2012.09.001","article-title":"Toxicity of MPTP on neurotransmission in three mouse models of Parkinson\u2019s disease","volume":"65","author":"Pain","year":"2013","journal-title":"Exp. Toxicol. Pathol."},{"key":"10.1016\/j.bbr.2019.111915_bib0270","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1093\/ijnp\/pyx024","article-title":"Effect of physical exercise and acute escitalopram on the excitability of brain monoamine neurons: in vivo electrophysiological study in rats","volume":"20","author":"Dremencov","year":"2017","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.bbr.2019.111915_bib0275","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0304-3940(98)00198-0","article-title":"Sprouting of the serotonergic afferents into striatum after selective lesion of the dopaminergic system by MPTP in adult mice","volume":"245","author":"Rozas","year":"1998","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.bbr.2019.111915_bib0280","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.bbr.2014.07.038","article-title":"The role of serotonin in adult hippocampal neurogenesis","volume":"277","author":"Alenina","year":"2015","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.bbr.2019.111915_bib0285","doi-asserted-by":"crossref","first-page":"8270","DOI":"10.1523\/JNEUROSCI.5855-12.2013","article-title":"Serotonin is required for exercise-induced adult hippocampal neurogenesis","volume":"33","author":"Klempin","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbr.2019.111915_bib0290","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.neuroscience.2005.06.065","article-title":"Effect of long-lasting serotonin depletion on environmental enrichment-induced neurogenesis in adult rat hippocampus and spatial learning","volume":"135","author":"Ueda","year":"2005","journal-title":"Neuroscience."},{"key":"10.1016\/j.bbr.2019.111915_bib0295","article-title":"Effects of physical exercise programs on cognitive function in Parkinson\u2019s disease patients: a systematic review of randomized controlled trials of the last 10 years","volume":"13","author":"da Silva","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.bbr.2019.111915_bib0300","doi-asserted-by":"crossref","first-page":"89","DOI":"10.2174\/1745017901814010089","article-title":"Physical exercise for parkinson\u2019s disease: clinical and experimental evidence","volume":"14","author":"de Carvalho","year":"2018","journal-title":"Clin. Pract. Epidemiol. Ment. Health"},{"key":"10.1016\/j.bbr.2019.111915_bib0305","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0183463","article-title":"Adult hippocampal neurogenesis poststroke: more new granule cells but aberrant morphology and impaired spatial memory","volume":"12","author":"Woitke","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.bbr.2019.111915_bib0310","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3389\/fncel.2017.00013","article-title":"Intense exercise promotes adult hippocampal neurogenesis but not spatial discrimination","volume":"11","author":"So","year":"2017","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.bbr.2019.111915_bib0315","article-title":"Donepezil rescues spatial learning and memory deficits following traumatic brain injury independent of its effects on neurogenesis","volume":"10","author":"Yu","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.bbr.2019.111915_bib0320","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3988\/jcn.2018.14.2.225","article-title":"An 8-Week low-intensity progressive cycling training improves motor functions in patients with early-stage parkinson\u2019s disease","volume":"14","author":"Chang","year":"2018","journal-title":"J. Clin. Neurol."},{"key":"10.1016\/j.bbr.2019.111915_bib0325","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1002\/mds.21360","article-title":"Predicting the cost of Parkinson\u2019s disease","volume":"22","author":"McCrone","year":"2007","journal-title":"Mov. Disord."},{"key":"10.1016\/j.bbr.2019.111915_bib0330","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1093\/ije\/dyt108","article-title":"Association between various sedentary behaviours and all-cause, cardiovascular disease and cancer mortality: the Multiethnic Cohort Study","volume":"42","author":"Kim","year":"2013","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.bbr.2019.111915_bib0335","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1002\/mds.26484","article-title":"The therapeutic potential of exercise to improve mood, cognition, and sleep in parkinson\u2019s disease","volume":"31","author":"Reynolds","year":"2016","journal-title":"Mov. Disord."},{"key":"10.1016\/j.bbr.2019.111915_bib0340","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1002\/mds.26291","article-title":"Exercise improves cognition in Parkinson\u2019s disease: the PRET-PD randomized, clinical trial","volume":"30","author":"David","year":"2015","journal-title":"Mov. Disord."}],"container-title":["Behavioural Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432819301718?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432819301718?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T13:11:16Z","timestamp":1759065076000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166432819301718"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":68,"alternative-id":["S0166432819301718"],"URL":"https:\/\/doi.org\/10.1016\/j.bbr.2019.111915","relation":{},"ISSN":["0166-4328"],"issn-type":[{"type":"print","value":"0166-4328"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Physical activity sustains memory retrieval in dopamine-depleted mice previously treated with L-Dopa","name":"articletitle","label":"Article Title"},{"value":"Behavioural Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbr.2019.111915","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"111915"}}