{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T16:57:41Z","timestamp":1782925061436,"version":"3.54.5"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"NERF, Nirma University","award":["ISNU\/12-13\/ E1AF\/AN"],"award-info":[{"award-number":["ISNU\/12-13\/ E1AF\/AN"]}]},{"name":"DSTSERB, Govt. of India","award":["EMR\/2015\/001027"],"award-info":[{"award-number":["EMR\/2015\/001027"]}]},{"name":"DST-FIST, Govt. of India","award":["SR\/FST\/LSI-682\/2016"],"award-info":[{"award-number":["SR\/FST\/LSI-682\/2016"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Behavioural Brain Research"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.bbr.2019.112029","type":"journal-article","created":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T11:11:13Z","timestamp":1560165073000},"page":"112029","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Hypoglycemia causes dysregulation of Neuregulin 1, ErbB receptors, Ki67 in cerebellum and brainstem during diabetes: Implications in motor function"],"prefix":"10.1016","volume":"372","author":[{"given":"Madhavi","family":"Joshi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amee","family":"Krishnakumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbr.2019.112029_bib0005","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a020602","article-title":"Central nervous system regenerative failure: role of oligodendrocytes, astrocytes, and microglia","volume":"7","author":"Silver","year":"2015","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.bbr.2019.112029_bib0010","doi-asserted-by":"crossref","first-page":"3417","DOI":"10.1242\/dev.148312","article-title":"Can injured adult CNS axons regenerate by recapitulating development?","volume":"144","author":"Hilton","year":"2017","journal-title":"Development"},{"key":"10.1016\/j.bbr.2019.112029_bib0015","doi-asserted-by":"crossref","first-page":"4","DOI":"10.3389\/fncel.2013.00004","article-title":"ErbB1-4-dependent EGF\/neuregulin signals and their cross talk in the central nervous system: pathological implications in schizophrenia and Parkinson\u2019s disease","volume":"7","author":"Iwakura","year":"2013","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.bbr.2019.112029_bib0020","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1001743","article-title":"Neuregulin and BDNF induce a switch to NMDA receptor-dependent myelination by oligodendrocytes","volume":"11","author":"Lundgaard","year":"2013","journal-title":"PLoS Biol."},{"key":"10.1016\/j.bbr.2019.112029_bib0025","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0014-4827(02)00102-7","article-title":"-Neuregulins: functions, forms, and signaling strategies","volume":"284","author":"Falls","year":"2003","journal-title":"Exp Cell Res."},{"key":"10.1016\/j.bbr.2019.112029_bib0030","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.mcn.2004.08.001","article-title":"Neuregulin-1\u03b2 induces neurite extension and arborization in cultured hippocampal neurons","volume":"27","author":"Gerecke","year":"2004","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.bbr.2019.112029_bib0035","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.brainres.2017.06.012","article-title":"Neuregulin-1 protects mouse cerebellum against oxidative stress and neuro inflammation","volume":"1670","author":"Xu","year":"2017","journal-title":"Brain Res."},{"key":"10.1016\/j.bbr.2019.112029_bib0040","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0130568","article-title":"Neuregulin 1 improves glucose tolerance in db\/db mice","volume":"10","author":"Ennequin","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.bbr.2019.112029_bib0045","doi-asserted-by":"crossref","first-page":"4995","DOI":"10.1073\/pnas.96.9.4995","article-title":"The ErbB2\/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derive growth factors","volume":"96","author":"Klapper","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bbr.2019.112029_bib0050","doi-asserted-by":"crossref","first-page":"7692","DOI":"10.1073\/pnas.1002753107","article-title":"ErbB3\/HER3 intracellular domain is competent to bind ATP and catalyze auto phosphorylation","volume":"107","author":"Shi","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bbr.2019.112029_bib0055","doi-asserted-by":"crossref","first-page":"4251","DOI":"10.1073\/pnas.0630496100","article-title":"Neuregulin 1-erbB2 signaling is required for the establishment of radial glia and their transformation into astrocytes in cerebral cortex","volume":"100","author":"Schmid","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bbr.2019.112029_bib0060","doi-asserted-by":"crossref","first-page":"2803","DOI":"10.1038\/sj.onc.1201466","article-title":"Differential expression of NDF\/neuregulin receptors ErbB-3 and ErbB-4 and involvement in inhibition of neuronal differentiation","volume":"15","author":"Pinkas-Kramarski","year":"1997","journal-title":"Oncogene."},{"key":"10.1016\/j.bbr.2019.112029_bib0065","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1161\/CIRCRESAHA.110.223545","article-title":"Oxidative stress and diabetic complications","volume":"107","author":"Giacco","year":"2010","journal-title":"Circ. Res."},{"key":"10.1016\/j.bbr.2019.112029_bib0070","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/2525967","article-title":"Oxidative stress in neurodegenerative diseases: from molecular mechanisms to clinical applications","volume":"2017","author":"Liu","year":"2017","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.bbr.2019.112029_bib0075","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1172\/JCI30077","article-title":"Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase","volume":"117","author":"Suh","year":"2007","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbr.2019.112029_bib0080","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.nicl.2012.09.004","article-title":"Abnormalities in the brain of streptozotocin-induced type 1 diabetic rats revealed by diffusion tensor imaging","volume":"1","author":"Huang","year":"2012","journal-title":"Neuroimage Clin."},{"key":"10.1016\/j.bbr.2019.112029_bib0085","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.cger.2008.03.011","article-title":"Diabetic neuropathy in older adults","volume":"24","author":"Vinik","year":"2008","journal-title":"Clin. Geriatr. Med."},{"key":"10.1016\/j.bbr.2019.112029_bib0090","doi-asserted-by":"crossref","first-page":"12841","DOI":"10.1038\/s41598-017-13079-8","article-title":"Contralateral cortico-ponto-cerebellar pathways reconstruction in humans in vivo: implications for reciprocal cerebro-cerebellar structural connectivity in motor and non-motor areas","volume":"7","author":"Palesi","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbr.2019.112029_bib0095","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1007\/s00221-006-0706-1","article-title":"Comparison of the electrically evoked leg withdrawal reflex in cerebellar patients and healthy controls","volume":"177","author":"Kolb","year":"2007","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.bbr.2019.112029_bib0100","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/nyas.13094","article-title":"Cerebellar contributions to motor control and language comprehension: searching for common computational principles","volume":"1369","author":"Moberget","year":"2016","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.bbr.2019.112029_bib0105","series-title":"Motor Output From the Brain and Spinal Cord","author":"Berkowitz","year":"2012"},{"key":"10.1016\/j.bbr.2019.112029_bib0110","doi-asserted-by":"crossref","first-page":"355","DOI":"10.3389\/fncel.2014.00355","article-title":"Experimentally induced diabetes causes glial activation, glutamate toxicity and cellular damage leading to changes in motor function","volume":"8","author":"Nagayach","year":"2014","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.bbr.2019.112029_bib0115","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/BF03006189","article-title":"Brain stem evoked responses in patients with diabetes mellitus","volume":"52","author":"Sharma","year":"2000","journal-title":"Indian J. Otolaryngol. Head Neck Surg."},{"key":"10.1016\/j.bbr.2019.112029_bib0120","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.neuroscience.2015.08.023","article-title":"Molecular and functional changes in glucokinase expression in the brainstem dorsal vagal complex in a murine model of type 1 diabetes","volume":"306","author":"Halmos","year":"2015","journal-title":"Neurosci."},{"key":"10.1016\/j.bbr.2019.112029_bib0125","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1212\/WNL.55.3.418","article-title":"Hypoglycemia-induced cerebellar dysfunction and quantitative positron emission tomography study","volume":"55","author":"Kim","year":"2000","journal-title":"Neurology."},{"key":"10.1016\/j.bbr.2019.112029_bib0130","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1097\/00006123-199908000-00040","article-title":"Brainstem dysfunction in chiari malformation presenting as profound hypoglycemia: presentation of four cases, review of the literature, and conjecture as to mechanism","volume":"45","author":"Rekate","year":"1999","journal-title":"Neurosurgery."},{"key":"10.1016\/j.bbr.2019.112029_bib0135","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1423-0127-17-7","article-title":"Hypoglycemia induced changes in cholinergic receptor expression in the cerebellum of diabetic rats","volume":"17","author":"Antony","year":"2010","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.bbr.2019.112029_bib0140","doi-asserted-by":"crossref","first-page":"900","DOI":"10.2337\/diab.44.8.900","article-title":"Brainstem dysfunction is provoked by a less pronounced hypoglycemic stimulus in diabetic BB rats","volume":"44","author":"Jacob","year":"1995","journal-title":"Diabetes."},{"issue":"5 Suppl","key":"10.1016\/j.bbr.2019.112029_bib0145","doi-asserted-by":"crossref","first-page":"6S","DOI":"10.1177\/1545968311410940","article-title":"Neurological principles and rehabilitation of action disorders: computation, anatomy, and physiology (CAP) model","volume":"25","author":"Frey","year":"2011","journal-title":"Neurorehabil. Neural Repair"},{"key":"10.1016\/j.bbr.2019.112029_bib0150","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s10571-008-9328-4","article-title":"Enhanced dopamine D1 and D2 receptor gene expression in the hippocampus of hypoglycaemic and diabetic rats","volume":"29","author":"Robinson","year":"2009","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.bbr.2019.112029_bib0155","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1111\/j.1471-4159.1966.tb09873.x","article-title":"Regional studies of catecholamines in the rat brain\u2010I: the disposition of [3H] norepinephrine,[3H] dopamine and [3H] dopa in various regions of the brain","volume":"13","author":"Glowinski","year":"1966","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbr.2019.112029_bib0160","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1006\/exnr.1998.6969","article-title":"Evidence that oxidative stress is associated with the pathophysiology of inherited hydrocephalus in the H-Tx rat model","volume":"155","author":"Socci","year":"1999","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bbr.2019.112029_bib0165","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.1093\/clinchem\/25.12.2026","article-title":"Kinetic determination of serum sorbitol dehydrogenase activity with a centrifugal analyzer","volume":"25","author":"Dooley","year":"1979","journal-title":"Clin. Chem."},{"key":"10.1016\/j.bbr.2019.112029_bib0170","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0003-9861(78)90479-4","article-title":"Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase","volume":"186","author":"Kono","year":"1978","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bbr.2019.112029_bib0175","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/nprot.2009.197","article-title":"Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue","volume":"5","author":"Weydert","year":"2010","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.bbr.2019.112029_bib0180","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbr.2019.112029_bib0185","doi-asserted-by":"crossref","first-page":"68","DOI":"10.4161\/oxim.2.2.8160","article-title":"Lipid peroxidation and antioxidant status in head and neck squamous cell carcinoma patients","volume":"2","author":"Gupta","year":"2009","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.bbr.2019.112029_bib0190","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/S1385-299X(02)00148-4","article-title":"A simplified method for combined immunohistochemistry and in-situ hybridization in fresh-frozen, cryocut mouse brain sections","volume":"9","author":"Newton","year":"2002","journal-title":"Brain Res. Brain Res. Protoc."},{"key":"10.1016\/j.bbr.2019.112029_bib0195","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2019","article-title":"Fiji: an open-source platform for biological-image analysis","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.bbr.2019.112029_bib0200","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.neuroscience.2011.11.016","article-title":"The grid-walking test: assessment of sensorimotor deficits after moderate or severe dopamine depletion by 6-hydroxydopamine lesions in the dorsal striatum and medial forebrain bundle","volume":"202","author":"Chao","year":"2012","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbr.2019.112029_bib0205","first-page":"189","article-title":"Cardiac autonomic neuropathy and QT interval length. A follow-up study in diabetic patients","volume":"46","author":"Jermendy","year":"1991","journal-title":"Acta Cardiol."},{"key":"10.1016\/j.bbr.2019.112029_bib0210","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.2337\/diabetes.54.6.1615","article-title":"The pathobiology of diabetic complications: a unifying mechanism","volume":"54","author":"Brownlee","year":"2005","journal-title":"Diabetes"},{"key":"10.1016\/j.bbr.2019.112029_bib0215","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.bbadis.2015.09.018","article-title":"Oxidative stress and its impact on neurons and glia in multiple sclerosis lesions","volume":"1862","author":"Lassmann","year":"2016","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbr.2019.112029_bib0220","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1080\/15476286.2017.1311456","article-title":"Hypoxia and Hypoglycemia synergistically regulate mRNA stability","volume":"14","author":"Carraway","year":"2017","journal-title":"RNA Biol."},{"key":"10.1016\/j.bbr.2019.112029_bib0225","first-page":"522","article-title":"ERBB3-mediated regulation of Bergmann glia proliferation in cerebellar lamination","volume":"142","author":"Sathyamurthy","year":"2015","journal-title":"Development"},{"key":"10.1016\/j.bbr.2019.112029_bib0230","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0037031","article-title":"Roles of molecular layer interneurons in sensory information processing in mouse cerebellar cortex Crus II in vivo","volume":"7","author":"Chu","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bbr.2019.112029_bib0235","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1007\/BF00234779","article-title":"The origin of cerebral-induced inhibition of Deiters neurones. I. Monosynaptic initiation of the inhibitory postsynaptic potentials","volume":"2","author":"Ito","year":"1966","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.bbr.2019.112029_bib0240","doi-asserted-by":"crossref","unstructured":"Q. He, I. Duguid, B. Clark, P. Panzanelli, B. Patel, P. Thomas, J.M. Fritschy, T.G. Smart, Interneuron - and GABA(A) receptor - specific inhibitory synaptic plasticity in cerebellar Purkinje cells, Nat. Commun. 6, 2015, 7364\u20137377.","DOI":"10.1038\/ncomms8364"},{"key":"10.1016\/j.bbr.2019.112029_bib0245","doi-asserted-by":"crossref","first-page":"4515","DOI":"10.1523\/JNEUROSCI.15-06-04515.1995","article-title":"AMPA receptor desensitization predicts the selective vulnerability of cerebellar Purkinje cells to excitotoxicity","volume":"15","author":"Brorson","year":"1995","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbr.2019.112029_bib0250","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.ejphar.2009.12.024","article-title":"Enhanced NMDAR1, NMDA2B and mGlu5 receptors gene expression in the cerebellum of insulin induced hypoglycaemic and streptozotocin induced diabetic rats","volume":"630","author":"Anu","year":"2010","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bbr.2019.112029_bib0255","doi-asserted-by":"crossref","first-page":"9477","DOI":"10.1073\/pnas.0901844106","article-title":"Erbin regulates NRG1 signaling and myelination","volume":"106","author":"Tao","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bbr.2019.112029_bib0260","doi-asserted-by":"crossref","first-page":"759","DOI":"10.2174\/138920310794557673","article-title":"Erbin, a negative regulator in diverse signal pathways","volume":"11","author":"Dan","year":"2010","journal-title":"Curr. Protein Pept. Sci."},{"key":"10.1016\/j.bbr.2019.112029_bib0265","doi-asserted-by":"crossref","first-page":"15169","DOI":"10.1523\/JNEUROSCI.2466-12.2012","article-title":"Erbin is required for myelination in regenerated axons after injury","volume":"32","author":"Liang","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbr.2019.112029_bib0270","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1007\/s00702-015-1475-4","article-title":"Brainstem control of locomotion and muscle tone with special reference to the role of the mesopontinetegmentum and medullary reticulospinal systems","volume":"123","author":"Takakusaki","year":"2016","journal-title":"J. Neural Transm. Vienna (Vienna)"},{"key":"10.1016\/j.bbr.2019.112029_bib0275","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1111\/avj.12346","article-title":"Axonal spheroid accumulation in the brainstem and spinal cord of a young angus cow with ataxia","volume":"93","author":"Hanshaw","year":"2015","journal-title":"Aust. Vet. J."},{"key":"10.1016\/j.bbr.2019.112029_bib0280","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1004515","article-title":"At the edge of chaos: how cerebellar granular layer network dynamics can provide the basis for temporal filters","volume":"11","author":"R\u00f6ssert","year":"2015","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.bbr.2019.112029_bib0285","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.comtox.2018.08.004","article-title":"Identification of small molecule activators for ErbB 4 receptor to enhance oligodendrocyte regeneration by in silico approach","volume":"8","author":"Joshi","year":"2018","journal-title":"Computational Toxicol."},{"key":"10.1016\/j.bbr.2019.112029_bib0290","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1097\/NEN.0b013e3182423c43","article-title":"Aberrant neuregulin 1 signaling in amyotrophic lateral sclerosis","volume":"71","author":"Song","year":"2012","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.bbr.2019.112029_bib0295","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0168-0102(98)00013-3","article-title":"Expression of receptors for neuregulins, ErbB2, ErbB3 and ErbB4, in developing mouse cerebellum","volume":"30","author":"Ozaki","year":"1998","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.bbr.2019.112029_bib0300","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1093\/emboj\/16.7.1647","article-title":"ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling","volume":"16","author":"Graus-Porta","year":"1997","journal-title":"EMBO J."},{"key":"10.1016\/j.bbr.2019.112029_bib0305","first-page":"3932","article-title":"Expression of the ErbB-neuregulin signaling network during human cerebellar development: implications for the biology of medulloblastoma","volume":"58","author":"Gilbertson","year":"1998","journal-title":"Cancer Res."},{"key":"10.1016\/j.bbr.2019.112029_bib0310","doi-asserted-by":"crossref","first-page":"7622","DOI":"10.1523\/JNEUROSCI.20-20-07622.2000","article-title":"Akt-mediated survival of oligodendrocytes induced by neuregulins","volume":"20","author":"Flores","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbr.2019.112029_bib0315","doi-asserted-by":"crossref","first-page":"21818","DOI":"10.1073\/pnas.1010669107","article-title":"ErbB4 in parvalbumin-positive inter neurons is critical for neuregulin 1 regulation of long-term potentiation","volume":"107","author":"Chen","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bbr.2019.112029_bib0320","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.neuron.2007.04.009","article-title":"Neuregulin-1 enhances depolarization-induced GABA release","volume":"54","author":"Woo","year":"2007","journal-title":"Neuron."},{"key":"10.1016\/j.bbr.2019.112029_bib0325","doi-asserted-by":"crossref","first-page":"26761","DOI":"10.1074\/jbc.272.42.26761","article-title":"A novel juxtamembrane domain isoform of HER4\/erbB4","volume":"272","author":"Elenius","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbr.2019.112029_bib0330","doi-asserted-by":"crossref","first-page":"19295","DOI":"10.1523\/JNEUROSCI.2090-13.2013","article-title":"Regulation of spine formation by ErbB4 in PV-positive interneurons","volume":"33","author":"Yin","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbr.2019.112029_bib0335","doi-asserted-by":"crossref","first-page":"19803","DOI":"10.1074\/jbc.C901015199","article-title":"Ligand discrimination in signaling through an ErbB4 receptor homodimer","volume":"275","author":"Sweeney","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbr.2019.112029_bib0340","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.cub.2005.02.030","article-title":"erbb3 and erbb2 are essential for schwann cell migration and myelination in zebrafish","volume":"15","author":"Lyons","year":"2005","journal-title":"Curr. Biol."},{"key":"10.1016\/j.bbr.2019.112029_bib0345","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1038\/39593","article-title":"Severe neuropathies in mice with targeted mutations in the ErbB3 receptor","volume":"389","author":"Riethmacher","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.bbr.2019.112029_bib0350","doi-asserted-by":"crossref","first-page":"2447","DOI":"10.1098\/rstb.2009.0064","article-title":"Brainstem: neural networks vital for life","volume":"364","author":"Nicholls","year":"2009","journal-title":"Philos Trans R SocLond B Biol Sci."},{"key":"10.1016\/j.bbr.2019.112029_bib0355","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1038\/378390a0","article-title":"Aberrant neural and cardiac development in mice lacking the erbB4 neuregulin receptor","volume":"378","author":"Gassmann","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.bbr.2019.112029_bib0360","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/S0079-6123(08)62247-5","article-title":"Disturbances of motor preparation in basal ganglia and cerebellar disorders","volume":"80","author":"Diener","year":"1989","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.bbr.2019.112029_bib0365","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1126\/science.1220845","article-title":"A critical period for social experience-dependent oligodendrocyte maturation and myelination","volume":"337","author":"Makinodan","year":"2012","journal-title":"Science"}],"container-title":["Behavioural Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016643281930470X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016643281930470X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T13:13:59Z","timestamp":1759065239000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016643281930470X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":73,"alternative-id":["S016643281930470X"],"URL":"https:\/\/doi.org\/10.1016\/j.bbr.2019.112029","relation":{},"ISSN":["0166-4328"],"issn-type":[{"value":"0166-4328","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypoglycemia causes dysregulation of Neuregulin 1, ErbB receptors, Ki67 in cerebellum and brainstem during diabetes: Implications in motor function","name":"articletitle","label":"Article Title"},{"value":"Behavioural Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbr.2019.112029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"112029"}}