{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T03:07:21Z","timestamp":1790305641720,"version":"4.1.0"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Ministry of the Economy and Competitiveness","award":["PSI2014-55785-C2-2-R"],"award-info":[{"award-number":["PSI2014-55785-C2-2-R"]}]},{"name":"Ministry of the Economy and Competitiveness","award":["PSI2014- 55785-C2-1-R"],"award-info":[{"award-number":["PSI2014- 55785-C2-1-R"]}]},{"name":"Commission for Universities and Research of the Ministry of Innovation, Universities and Enterprise of the Generalitat de Catalunya","award":["2013 FI_B00170"],"award-info":[{"award-number":["2013 FI_B00170"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Behavioural Brain Research"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.bbr.2020.112552","type":"journal-article","created":{"date-parts":[[2020,2,10]],"date-time":"2020-02-10T11:30:57Z","timestamp":1581334257000},"page":"112552","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Improvement of APOE4-dependent non-cognitive behavioural traits by postnatal cholinergic stimulation in female mice"],"prefix":"10.1016","volume":"384","author":[{"given":"Fiona","family":"Peris-Sampedro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laia","family":"Guardia-Escote","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pia","family":"Basaure","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Cabr\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Teresa","family":"Colomina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbr.2020.112552_bib0005","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1146\/annurev.genom.1.1.507","article-title":"Apolipoprotein E: far more than a lipid transport protein","volume":"1","author":"Mahley","year":"2000","journal-title":"Annu. Rev. Genomics Hum. Genet."},{"issue":"5","key":"10.1016\/j.bbr.2020.112552_bib0010","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.neurobiolaging.2003.12.023","article-title":"ApoE genotype accounts for the vast majority of AD risk and AD pathology","volume":"25","author":"Raber","year":"2004","journal-title":"Neurobiol. Aging"},{"issue":"2","key":"10.1016\/j.bbr.2020.112552_bib0015","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1007\/s11682-013-9272-x","article-title":"Apolipoprotein E, gender, and Alzheimer\u2019s disease: an overlooked, but potent and promising interaction","volume":"8","author":"Ungar","year":"2014","journal-title":"Brain Imaging Behav."},{"issue":"1","key":"10.1016\/j.bbr.2020.112552_bib0020","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.neuroscience.2007.03.005","article-title":"Effects of sex and APOE epsilon4 on object recognition and spatial navigation in the elderly","volume":"147","author":"Berteau-Pavy","year":"2007","journal-title":"Neuroscience"},{"issue":"1","key":"10.1016\/j.bbr.2020.112552_bib0025","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.neuroscience.2009.04.006","article-title":"Endophenotypes in normal brain morphology and Alzheimer\u2019s disease: a review","volume":"164","author":"Reitz","year":"2009","journal-title":"Neuroscience"},{"issue":"2","key":"10.1016\/j.bbr.2020.112552_bib0030","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.bbr.2008.05.008","article-title":"Middle-aged human apoE4 targeted-replacement mice show retention deficits on a wide range of spatial memory tasks","volume":"193","author":"Bour","year":"2008","journal-title":"Behav. Brain Res."},{"issue":"1","key":"10.1016\/j.bbr.2020.112552_bib0035","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1007\/s11682-012-9187-y","article-title":"Default mode network activity and white matter integrity in healthy middle-aged ApoE4 carriers","volume":"7","author":"Patel","year":"2013","journal-title":"Brain Imaging Behav."},{"issue":"1","key":"10.1016\/j.bbr.2020.112552_bib0040","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.expneurol.2012.06.015","article-title":"Behavioral phenotype and BDNF differences related to apoE isoforms and sex in young transgenic mice","volume":"237","author":"Reverte","year":"2012","journal-title":"Exp. Neurol."},{"issue":"2","key":"10.1016\/j.bbr.2020.112552_bib0045","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.neurobiolaging.2010.03.002","article-title":"Apolipoprotein E isoform-dependent effects on anxiety and cognition in female TR mice","volume":"33","author":"Siegel","year":"2012","journal-title":"Neurobiol. Aging"},{"issue":"6","key":"10.1016\/j.bbr.2020.112552_bib0050","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1111\/jnc.13737","article-title":"Genotype differences in anxiety and fear learning and memory of WT and ApoE4 mice associated with enhanced generation of hippocampal reactive oxygen species","volume":"138","author":"Villasana","year":"2016","journal-title":"J. Neurochem."},{"issue":"1","key":"10.1016\/j.bbr.2020.112552_bib0055","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3233\/JAD-2011-110554","article-title":"Association of apolipoprotein E epsilon4 (ApoE epsilon4) homozygosity with psychiatric behavioral symptoms","volume":"28","author":"Michels","year":"2012","journal-title":"J. Alzheimers Dis."},{"issue":"5","key":"10.1016\/j.bbr.2020.112552_bib0060","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.neurobiolaging.2004.06.003","article-title":"ApoE isoforms and measures of anxiety in probable AD patients and Apoe-\/- mice","volume":"26","author":"Robertson","year":"2005","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.bbr.2020.112552_bib0065","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.fct.2016.03.029","article-title":"Apolipoprotein E (APOE) genotype and the pesticide chlorpyrifos modulate attention, motivation and impulsivity in female mice in the 5-choice serial reaction time task","volume":"92","author":"Peris-Sampedro","year":"2016","journal-title":"Food Chem. Toxicol."},{"issue":"2","key":"10.1016\/j.bbr.2020.112552_bib0070","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s00213-015-4113-9","article-title":"Attentional performance, impulsivity, and related neurotransmitter systems in apoE2, apoE3, and apoE4 female transgenic mice","volume":"233","author":"Reverte","year":"2016","journal-title":"Psychopharmacology"},{"issue":"1","key":"10.1016\/j.bbr.2020.112552_bib0075","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.neulet.2006.08.061","article-title":"Cortical acetylcholine esterase activity and ApoE4-genotype in Alzheimer disease","volume":"408","author":"Eggers","year":"2006","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.bbr.2020.112552_bib0080","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.fct.2018.04.065","article-title":"Postnatal chlorpyrifos exposure and apolipoprotein E (APOE) genotype differentially affect cholinergic expression and developmental parameters in transgenic mice","volume":"118","author":"Basaure","year":"2018","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.bbr.2020.112552_bib0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.fct.2018.09.069","article-title":"Postnatal exposure to chlorpyrifos produces long-term effects on spatial memory and the cholinergic system in mice in a sex- and APOE genotype-dependent manner","volume":"122","author":"Guardia-Escote","year":"2018","journal-title":"Food Chem. Toxicol."},{"issue":"19","key":"10.1016\/j.bbr.2020.112552_bib0090","doi-asserted-by":"crossref","first-page":"11445","DOI":"10.1073\/pnas.95.19.11445","article-title":"Aggravated decrease in the activity of nucleus basalis neurons in Alzheimer\u2019s disease is apolipoprotein E-type dependent","volume":"95","author":"Salehi","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"3","key":"10.1016\/j.bbr.2020.112552_bib0095","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1007\/s00204-019-02387-9","article-title":"Learning, memory and the expression of cholinergic components in mice are modulated by the pesticide chlorpyrifos depending upon age at exposure and apolipoprotein E (APOE) genotype","volume":"93","author":"Basaure","year":"2019","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.bbr.2020.112552_bib0100","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.physbeh.2015.03.006","article-title":"Chronic exposure to chlorpyrifos triggered body weight increase and memory impairment depending on human apoE polymorphisms in a targeted replacement mouse model","volume":"144","author":"Peris-Sampedro","year":"2015","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.bbr.2020.112552_bib0105","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.envres.2015.06.036","article-title":"Adulthood dietary exposure to a common pesticide leads to an obese-like phenotype and a diabetic profile in apoE3 mice","volume":"142","author":"Peris-Sampedro","year":"2015","journal-title":"Environ. Res."},{"issue":"5","key":"10.1016\/j.bbr.2020.112552_bib0110","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1007\/s00204-018-2174-3","article-title":"New mechanistic insights on the metabolic-disruptor role of chlorpyrifos in apoE mice: a focus on insulin- and leptin-signalling pathways","volume":"92","author":"Peris-Sampedro","year":"2018","journal-title":"Arch. Toxicol."},{"issue":"29","key":"10.1016\/j.bbr.2020.112552_bib0115","doi-asserted-by":"crossref","first-page":"17972","DOI":"10.1074\/jbc.272.29.17972","article-title":"Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis","volume":"272","author":"Sullivan","year":"1997","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.bbr.2020.112552_bib0120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/10408440802272158","article-title":"Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment","volume":"38","author":"Eaton","year":"2008","journal-title":"Crit. Rev. Toxicol."},{"issue":"2","key":"10.1016\/j.bbr.2020.112552_bib0125","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.toxlet.2007.11.003","article-title":"Long-term monoamine changes in the striatum and nucleus accumbens after acute chlorpyrifos exposure","volume":"176","author":"Moreno","year":"2008","journal-title":"Toxicol. Lett."},{"issue":"2","key":"10.1016\/j.bbr.2020.112552_bib0130","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/j.1471-4159.2011.07428.x","article-title":"Organophosphates dysregulate dopamine signaling, glutamatergic neurotransmission, and induce neuronal injury markers in striatum","volume":"119","author":"Torres-Altoro","year":"2011","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbr.2020.112552_bib0135","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.brainresbull.2015.01.003","article-title":"Prenatal nicotine changes the response to postnatal chlorpyrifos: interactions targeting serotonergic synaptic function and cognition","volume":"111","author":"Slotkin","year":"2015","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.bbr.2020.112552_bib0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbr.2016.10.014","article-title":"Two cholinesterase inhibitors trigger dissimilar effects on behavior and body weight in C57BL\/6 mice: the case of chlorpyrifos and rivastigmine","volume":"318","author":"Basaure","year":"2017","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.bbr.2020.112552_bib0145","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.fct.2014.07.036","article-title":"Impaired retention in A\u03b2PP Swedish mice six months after oral exposure to chlorpyrifos","volume":"72","author":"Peris-Sampedro","year":"2014","journal-title":"Food Chem. Toxicol."},{"issue":"5","key":"10.1016\/j.bbr.2020.112552_bib0150","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1002\/bdrb.20090","article-title":"Postnatal growth and morphological development of the brain: a species comparison","volume":"77","author":"Watson","year":"2006","journal-title":"Birth Defects Res. B Dev. Reprod. Toxicol."},{"issue":"1","key":"10.1016\/j.bbr.2020.112552_bib0155","doi-asserted-by":"crossref","DOI":"10.1002\/0471142301.nsa04is48","article-title":"Assessing reproductive status\/stages in mice","volume":"48","author":"Caligioni","year":"2009","journal-title":"Curr. Protoc. Neurosci."},{"issue":"4","key":"10.1016\/j.bbr.2020.112552_bib0160","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1111\/j.1601-183X.2009.00476.x","article-title":"Progesterone modulation of alpha5 nAChR subunits influences anxiety-related behavior during estrus cycle","volume":"8","author":"Gangitano","year":"2009","journal-title":"Genes Brain Behav."},{"issue":"13","key":"10.1016\/j.bbr.2020.112552_bib0165","doi-asserted-by":"crossref","first-page":"2647","DOI":"10.1007\/s00213-014-3433-5","article-title":"Estrous cycle and sex affect cocaine-induced behavioural changes in CD1 mice","volume":"231","author":"Martini","year":"2014","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.bbr.2020.112552_bib0170","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.bbr.2014.09.043","article-title":"High maternal choline consumption during pregnancy and nursing alleviates deficits in social interaction and improves anxiety-like behaviors in the BTBR T+Itpr3tf\/J mouse model of autism","volume":"278","author":"Langley","year":"2015","journal-title":"Behav. Brain Res."},{"issue":"2","key":"10.1016\/j.bbr.2020.112552_bib0175","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.vascn.2013.12.005","article-title":"Assessing anxiety in C57BL\/6J mice: a pharmacological characterization of the open-field and light\/dark tests","volume":"69","author":"Heredia","year":"2014","journal-title":"J. Pharmacol. Toxicol. Methods"},{"issue":"2","key":"10.1016\/j.bbr.2020.112552_bib0180","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0091-3057(80)90067-2","article-title":"Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines","volume":"13","author":"Crawley","year":"1980","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"5","key":"10.1016\/j.bbr.2020.112552_bib0185","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/0091-3057(81)90007-1","article-title":"Neuropharmacologic specificity of a simple animal model for the behavioral actions of benzodiazepines","volume":"15","author":"Crawley","year":"1981","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.bbr.2020.112552_bib0190","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.bbr.2013.05.035","article-title":"Use of the light\/dark test for anxiety in adult and adolescent male rats","volume":"256","author":"Arrant","year":"2013","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.bbr.2020.112552_bib0195","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.physbeh.2014.05.006","article-title":"Assessment of mouse anxiety-like behavior in the light-dark box and open-field arena: role of equipment and procedure","volume":"133","author":"Kulesskaya","year":"2014","journal-title":"Physiol. Behav."},{"issue":"1-3","key":"10.1016\/j.bbr.2020.112552_bib0200","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0014-2999(03)01274-3","article-title":"The mouse light\/dark box test","volume":"463","author":"Bourin","year":"2003","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bbr.2020.112552_bib0205","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.appet.2014.02.020","article-title":"Large, binge-type meals of high fat diet change feeding behaviour and entrain food anticipatory activity in mice","volume":"77","author":"Bake","year":"2014","journal-title":"Appetite"},{"issue":"4","key":"10.1016\/j.bbr.2020.112552_bib0210","doi-asserted-by":"crossref","DOI":"10.1111\/jne.12463","article-title":"Acute ghrelin changes food preference from a high-fat diet to chow during binge-like eating in rodents","volume":"29","author":"Bake","year":"2017","journal-title":"J. Neuroendocrinol."},{"issue":"6","key":"10.1016\/j.bbr.2020.112552_bib0215","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1097\/00019442-200506000-00005","article-title":"Neuropsychiatric symptoms and quality of life in Alzheimer disease","volume":"13","author":"Shin","year":"2005","journal-title":"Am. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.bbr.2020.112552_bib0220","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.bbr.2013.10.017","article-title":"Bizarre behaviors and risk assessment in 3xTg-AD mice at early stages of the disease","volume":"258","author":"Baeta-Corral","year":"2014","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.bbr.2020.112552_bib0225","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.bbr.2014.04.055","article-title":"NQO1 and SIRT1 as premorbid and prodromal indicators of AD in 3xTg-AD mice","volume":"271","author":"Torres-Lista","year":"2014","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.bbr.2020.112552_bib0230","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.beproc.2015.05.001","article-title":"Marble-burying is enhanced in 3xTg-AD mice, can be reversed by risperidone and it is modulable by handling","volume":"116","author":"Torres-Lista","year":"2015","journal-title":"Behav. Processes"},{"key":"10.1016\/j.bbr.2020.112552_bib0235","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.physbeh.2017.03.039","article-title":"Extended vs. Brief intermittent access to palatable food differently promote binge-like intake, rejection of less preferred food, and weight cycling in female rats","volume":"177","author":"Kreisler","year":"2017","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.bbr.2020.112552_bib0240","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.appet.2018.07.025","article-title":"The duration of intermittent access to preferred sucrose-rich food affects binge-like intake, fat accumulation, and fasting glucose in male rats","volume":"130","author":"Kreisler","year":"2018","journal-title":"Appetite"},{"issue":"8","key":"10.1016\/j.bbr.2020.112552_bib0245","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1037\/amp0000059","article-title":"Liking, wanting, and the incentive-sensitization theory of addiction","volume":"71","author":"Berridge","year":"2016","journal-title":"Am. Psychol."},{"key":"10.1016\/j.bbr.2020.112552_bib0250","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1146\/annurev-pharmtox-010611-134625","article-title":"Addiction circuitry in the human brain","volume":"52","author":"Volkow","year":"2012","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"issue":"4","key":"10.1016\/j.bbr.2020.112552_bib0255","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.neuron.2011.01.020","article-title":"Impulsivity, compulsivity, and top-down cognitive control","volume":"69","author":"Dalley","year":"2011","journal-title":"Neuron"},{"issue":"A","key":"10.1016\/j.bbr.2020.112552_bib0260","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.brainres.2014.09.012","article-title":"Fronto-striatal circuits in response-inhibition: relevance to addiction","volume":"1628","author":"Morein-Zamir","year":"2015","journal-title":"Brain Res."},{"issue":"6","key":"10.1016\/j.bbr.2020.112552_bib0265","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1111\/adb.12434","article-title":"The infralimbic and prelimbic cortices contribute to the inhibitory control of cocaine-seeking behavior during a discriminative stimulus task in rats","volume":"22","author":"Gutman","year":"2017","journal-title":"Addict. Biol."},{"issue":"2","key":"10.1016\/j.bbr.2020.112552_bib0270","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ntt.2007.10.004","article-title":"Rats gain excess weight after developmental exposure to the organophosphorothionate pesticide, chlorpyrifos","volume":"30","author":"Lassiter","year":"2008","journal-title":"Neurotoxicol. Teratol."},{"issue":"3","key":"10.1016\/j.bbr.2020.112552_bib0275","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.ntt.2012.02.003","article-title":"Neurobehavioral assessment of mice following repeated postnatal exposure to chlorpyrifos-oxon","volume":"34","author":"Cole","year":"2012","journal-title":"Neurotoxicol. Teratol."},{"issue":"3","key":"10.1016\/j.bbr.2020.112552_bib0280","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0121663","article-title":"Prenatal exposure to a common organophosphate insecticide delays motor development in a mouse model of idiopathic autism","volume":"10","author":"De Felice","year":"2015","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.bbr.2020.112552_bib0285","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1002\/oby.22381","article-title":"Impact of free-choice diets high in fat and different sugars on metabolic outcome and anxiety-like behavior in rats","volume":"27","author":"Peris-Sampedro","year":"2019","journal-title":"Obesity"},{"issue":"1","key":"10.1016\/j.bbr.2020.112552_bib0290","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.brainresbull.2009.07.002","article-title":"Neonatal exposure to parathion alters lipid metabolism in adulthood: interactions with dietary fat intake and implications for neurodevelopmental deficits","volume":"81","author":"Lassiter","year":"2010","journal-title":"Brain Res. Bull."},{"issue":"6","key":"10.1016\/j.bbr.2020.112552_bib0295","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1289\/ehp.0800459","article-title":"Consumption of a high-fat diet in adulthood ameliorates the effects of neonatal parathion exposure on acetylcholine systems in rat brain regions","volume":"117","author":"Slotkin","year":"2009","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.bbr.2020.112552_bib0300","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.neuro.2015.11.016","article-title":"Decreased anxiety in juvenile rats following exposure to low levels of chlorpyrifos during development","volume":"59","author":"Carr","year":"2017","journal-title":"Neurotoxicology"},{"issue":"2","key":"10.1016\/j.bbr.2020.112552_bib0305","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.ntt.2009.08.008","article-title":"Anxiety in adult female mice following perinatal exposure to chlorpyrifos","volume":"32","author":"Braquenier","year":"2010","journal-title":"Neurotoxicol. Teratol."},{"issue":"1","key":"10.1016\/j.bbr.2020.112552_bib0310","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s00213-009-1713-2","article-title":"Gestational exposure to the organophosphate chlorpyrifos alters social-emotional behaviour and impairs responsiveness to the serotonin transporter inhibitor fluvoxamine in mice","volume":"208","author":"Venerosi","year":"2010","journal-title":"Psychopharmacology"},{"issue":"3","key":"10.1016\/j.bbr.2020.112552_bib0315","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.reprotox.2010.07.012","article-title":"Does early-life exposure to organophosphate insecticides lead to prediabetes and obesity?","volume":"31","author":"Slotkin","year":"2011","journal-title":"Reprod. Toxicol."}],"container-title":["Behavioural Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432819316493?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432819316493?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T13:15:55Z","timestamp":1759065355000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166432819316493"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":63,"alternative-id":["S0166432819316493"],"URL":"https:\/\/doi.org\/10.1016\/j.bbr.2020.112552","relation":{},"ISSN":["0166-4328"],"issn-type":[{"value":"0166-4328","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Improvement of APOE4-dependent non-cognitive behavioural traits by postnatal cholinergic stimulation in female mice","name":"articletitle","label":"Article Title"},{"value":"Behavioural Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbr.2020.112552","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"112552"}}