{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T09:09:36Z","timestamp":1779008976175,"version":"3.51.4"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of Hunan Province","doi-asserted-by":"publisher","award":["2025JJ50591"],"award-info":[{"award-number":["2025JJ50591"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32571264"],"award-info":[{"award-number":["32571264"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82201702"],"award-info":[{"award-number":["82201702"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Behavioural Brain Research"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.bbr.2026.116119","type":"journal-article","created":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T00:18:55Z","timestamp":1771633135000},"page":"116119","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Aberrant brain activity during sad-happy emotional switching in adolescents with bipolar disorder: A functional MRI study"],"prefix":"10.1016","volume":"505","author":[{"given":"Lin","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liying","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feifei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinfan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Grecucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoping","family":"Yi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bihong T.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"10159","key":"10.1016\/j.bbr.2026.116119_bib1","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1016\/S0140-6736(18)32279-7","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990\u20132017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"392","author":"James","year":"2018","journal-title":"lancet"},{"issue":"9","key":"10.1016\/j.bbr.2026.116119_bib2","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1038\/mp.2008.65","article-title":"A neural model of voluntary and automatic emotion regulation: implications for understanding the pathophysiology and neurodevelopment of bipolar disorder","volume":"13","author":"Phillips","year":"2008","journal-title":"Mol. Psychiatry"},{"issue":"1","key":"10.1016\/j.bbr.2026.116119_bib3","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.wpsyc.2012.01.006","article-title":"Age at onset versus family history and clinical outcomes in 1,665 international bipolar-I disorder patients","volume":"11","author":"Baldessarini","year":"2012","journal-title":"World Psychiatry"},{"key":"10.1016\/j.bbr.2026.116119_bib4","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.cpr.2017.11.006","article-title":"Cognitive deficits in bipolar disorders: Implications for emotion","volume":"59","author":"Lima","year":"2018","journal-title":"Clin. Psychol. Rev."},{"issue":"6","key":"10.1016\/j.bbr.2026.116119_bib5","doi-asserted-by":"crossref","DOI":"10.1111\/acps.13626","article-title":"Adaptive and maladaptive emotion regulation in bipolar disorder","volume":"148","author":"Frodl","year":"2023","journal-title":"Acta Psychiatr. Scand."},{"issue":"5","key":"10.1016\/j.bbr.2026.116119_bib6","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1037\/a0016277","article-title":"A meta-analytic investigation of neurocognitive deficits in bipolar illness: profile and effects of clinical state","volume":"23","author":"Kurtz","year":"2009","journal-title":"Neuropsychology"},{"issue":"8","key":"10.1016\/j.bbr.2026.116119_bib7","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1111\/j.1524-4733.2010.00768.x","article-title":"Functional impairment and disability across mood states in bipolar disorder","volume":"13","author":"Rosa","year":"2010","journal-title":"Value Health"},{"key":"10.1016\/j.bbr.2026.116119_bib8","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.jad.2022.01.102","article-title":"Difficulties in emotion regulation in bipolar disorder: a systematic review and meta-analysis","volume":"302","author":"Miola","year":"2022","journal-title":"J. Affect. Disord."},{"issue":"1","key":"10.1016\/j.bbr.2026.116119_bib9","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1186\/s12888-021-03392-y","article-title":"Prevalence and risk factors for non-suicidal self-injury among patients with depression or bipolar disorder in China","volume":"21","author":"Wang","year":"2021","journal-title":"BMC Psychiatry"},{"issue":"9","key":"10.1016\/j.bbr.2026.116119_bib10","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1016\/j.brat.2008.05.004","article-title":"Transdiagnostic emotion regulation processes in bipolar disorder and insomnia","volume":"46","author":"Gruber","year":"2008","journal-title":"Behav. Res. Ther."},{"issue":"2","key":"10.1016\/j.bbr.2026.116119_bib11","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.biopsych.2012.06.036","article-title":"Emotional response inhibition in bipolar disorder: a functional magnetic resonance imaging study of trait-and state-related abnormalities","volume":"73","author":"Hummer","year":"2013","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbr.2026.116119_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.dcn.2021.100980","article-title":"Increased integration between default mode and task-relevant networks in children with ADHD is associated with impaired response control","volume":"50","author":"Duffy","year":"2021","journal-title":"Dev. Cogn. Neurosci."},{"key":"10.1016\/j.bbr.2026.116119_bib13","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.jad.2023.06.030","article-title":"Deficits in sustained attention in adolescents with bipolar disorder during their first manic episode","volume":"339","author":"Patino","year":"2023","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.bbr.2026.116119_bib14","first-page":"1","article-title":"Network-wide aberrancies in neuronal activity during working memory in a large cohort of patients with mood disorders: associations with cognitive impairment and functional disability","author":"Damgaard","year":"2025","journal-title":"Mol. Psychiatry"},{"issue":"2","key":"10.1016\/j.bbr.2026.116119_bib15","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1002\/hbm.22655","article-title":"Functional connectivity and neuronal variability of resting state activity in bipolar disorder\u2014reduction and decoupling in anterior cortical midline structures","volume":"36","author":"Magioncalda","year":"2015","journal-title":"Hum. Brain Mapp."},{"issue":"7","key":"10.1016\/j.bbr.2026.116119_bib16","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1097\/00004583-199707000-00021","article-title":"Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): initial reliability and validity data","volume":"36","author":"Kaufman","year":"1997","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"issue":"5","key":"10.1016\/j.bbr.2026.116119_bib17","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1192\/bjp.133.5.429","article-title":"A rating scale for mania: reliability, validity and sensitivity","volume":"133","author":"Young","year":"1978","journal-title":"Br. J. Psychiatry"},{"issue":"2","key":"10.1016\/j.bbr.2026.116119_bib18","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/j.1469-7610.1995.tb01828.x","article-title":"Properties of the mood and feelings questionnaire in adolescent psychiatric outpatients: a research note","volume":"36","author":"Wood","year":"1995","journal-title":"J. Child Psychol. Psychiatry"},{"issue":"2","key":"10.1016\/j.bbr.2026.116119_bib19","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0165-1781(89)90047-4","article-title":"The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research","volume":"28","author":"Buysse","year":"1989","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.bbr.2026.116119_bib20","doi-asserted-by":"crossref","first-page":"557","DOI":"10.3389\/fpsyg.2017.00557","article-title":"The stroop color and word test","volume":"8","author":"Scarpina","year":"2017","journal-title":"Front. Psychol."},{"issue":"3","key":"10.1016\/j.bbr.2026.116119_bib21","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1080\/13803390490510149","article-title":"Frontal lobe damage and tests of executive processing: a meta-analysis of the category test, stroop test, and trail-making test","volume":"26","author":"Demakis","year":"2004","journal-title":"J. Clin. Exp. Neuropsychol."},{"issue":"4","key":"10.1016\/j.bbr.2026.116119_bib22","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1176\/ajp.2007.164.4.638","article-title":"Fronto-striatal overactivation in euthymic bipolar patients during an emotional go\/nogo task","volume":"164","author":"Wessa","year":"2007","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.bbr.2026.116119_bib23","series-title":"Pictures of Facial Affect","author":"Friesen","year":"1976"},{"key":"10.1016\/j.bbr.2026.116119_bib24","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.jad.2020.02.042","article-title":"Gray matter voxel-based morphometry in mania and remission states of children with bipolar disorder","volume":"268","author":"Xiao","year":"2020","journal-title":"J. Affect. Disord."},{"issue":"7","key":"10.1016\/j.bbr.2026.116119_bib25","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1111\/j.1399-5618.2010.00863.x","article-title":"Altered neural function in pediatric bipolar disorder during reversal learning","volume":"12","author":"Dickstein","year":"2010","journal-title":"Bipolar Disord."},{"issue":"1","key":"10.1016\/j.bbr.2026.116119_bib26","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1186\/s12888-023-05083-2","article-title":"Intrinsic functional connectivity correlates of cognitive deficits involving sustained attention and executive function in bipolar disorder","volume":"23","author":"Wu","year":"2023","journal-title":"BMC Psychiatry"},{"issue":"9","key":"10.1016\/j.bbr.2026.116119_bib27","doi-asserted-by":"crossref","first-page":"3598","DOI":"10.1093\/brain\/awad181","article-title":"The functional role of the precuneus","volume":"146","author":"Dadario","year":"2023","journal-title":"Brain"},{"issue":"4","key":"10.1016\/j.bbr.2026.116119_bib28","doi-asserted-by":"crossref","first-page":"395","DOI":"10.3390\/biology14040395","article-title":"The journey of the default mode network: development, function, and impact on mental health","volume":"14","author":"Azarias","year":"2025","journal-title":"Biology"},{"issue":"7","key":"10.1016\/j.bbr.2026.116119_bib29","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1111\/bdi.12007","article-title":"Impaired sustained attention in euthymic bipolar disorder patients and non-affected relatives: an fMRI study","volume":"14","author":"Sepede","year":"2012","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.bbr.2026.116119_bib30","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s11065-014-9246-9","article-title":"Contributions of the insula to cognition and emotion","volume":"24","author":"Gasquoine","year":"2014","journal-title":"Neuropsychol. Rev."},{"key":"10.1016\/j.bbr.2026.116119_bib31","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1007\/s00429-010-0262-0","article-title":"Saliency, switching, attention and control: a network model of insula function","volume":"214","author":"Menon","year":"2010","journal-title":"Brain Struct. Funct."},{"issue":"34","key":"10.1016\/j.bbr.2026.116119_bib32","doi-asserted-by":"crossref","first-page":"12569","DOI":"10.1073\/pnas.0800005105","article-title":"A critical role for the right fronto-insular cortex in switching between central-executive and default-mode networks","volume":"105","author":"Sridharan","year":"2008","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.bbr.2026.116119_bib33","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1016\/j.jad.2020.07.021","article-title":"The role of the MTG in negative emotional processing in young adults with autistic-like traits: a fMRI task study","volume":"276","author":"Yu","year":"2020","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.bbr.2026.116119_bib34","doi-asserted-by":"crossref","first-page":"11204","DOI":"10.1038\/s41598-022-15489-9","article-title":"Resting-state functional connectivity of salience network in schizophrenia and depression","volume":"12","author":"Huang","year":"2022","journal-title":"Sci. Rep."},{"issue":"6","key":"10.1016\/j.bbr.2026.116119_bib35","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1111\/cns.14092","article-title":"Functional and structural alterations of dorsal attention network in preclinical and early-stage Alzheimer's disease","volume":"29","author":"Wu","year":"2023","journal-title":"CNS Neurosci. Ther."},{"issue":"12","key":"10.1016\/j.bbr.2026.116119_bib36","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1002328","article-title":"The contribution of network organization and integration to the development of cognitive control","volume":"13","author":"Marek","year":"2015","journal-title":"PLoS Biol."},{"issue":"3","key":"10.1016\/j.bbr.2026.116119_bib37","doi-asserted-by":"crossref","DOI":"10.1111\/desc.12571","article-title":"Salience network response to changes in emotional expressions of others is heightened during early adolescence: relevance for social functioning","volume":"21","author":"Rosen","year":"2018","journal-title":"Dev. Sci."},{"issue":"2","key":"10.1016\/j.bbr.2026.116119_bib38","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1007\/s12311-011-0321-y","article-title":"From movement to thought: executive function, embodied cognition, and the cerebellum","volume":"11","author":"Koziol","year":"2012","journal-title":"Cerebellum"},{"issue":"4","key":"10.1016\/j.bbr.2026.116119_bib39","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1016\/j.brs.2022.06.004","article-title":"Effect of cerebellum stimulation on cognitive recovery in patients with Alzheimer disease: a randomized clinical trial","volume":"15","author":"Yao","year":"2022","journal-title":"Brain Stimul."},{"issue":"11","key":"10.1016\/j.bbr.2026.116119_bib40","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1016\/j.euroneuro.2016.06.006","article-title":"Brain functional effects of psychopharmacological treatments in bipolar disorder","volume":"26","author":"Laidi","year":"2016","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.bbr.2026.116119_bib41","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.jad.2020.12.157","article-title":"Children with euthymic bipolar disorder during an emotional go\/nogo task: insights into the neural circuits of cognitive-emotional regulation","volume":"282","author":"Xiao","year":"2021","journal-title":"J. Affect. Disord."}],"container-title":["Behavioural Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432826000951?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432826000951?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T08:31:36Z","timestamp":1779006696000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166432826000951"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":41,"alternative-id":["S0166432826000951"],"URL":"https:\/\/doi.org\/10.1016\/j.bbr.2026.116119","relation":{},"ISSN":["0166-4328"],"issn-type":[{"value":"0166-4328","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aberrant brain activity during sad-happy emotional switching in adolescents with bipolar disorder: A functional MRI study","name":"articletitle","label":"Article Title"},{"value":"Behavioural Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbr.2026.116119","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116119"}}