{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T17:35:21Z","timestamp":1786556121578,"version":"build-2736575974"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Behavioural Brain Research"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.bbr.2026.116361","type":"journal-article","created":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T12:42:32Z","timestamp":1783600952000},"page":"116361","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Complementary functional gradient and SFC analyses reveal network abnormalities in adolescent depression subtypes"],"prefix":"10.1016","volume":"514","author":[{"given":"Chengyang","family":"Zeng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhigang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sijin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhijun","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9795-7807","authenticated-orcid":false,"given":"Yu","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuzhen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbr.2026.116361_bib1","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1146\/annurev-psych-010213-115202","article-title":"Is adolescence a sensitive period for sociocultural processing?","volume":"65","author":"Blakemore","year":"2014","journal-title":"Annu. Rev. Psychol."},{"key":"10.1016\/j.bbr.2026.116361_bib2","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1038\/13158","article-title":"Brain development during childhood and adolescence: a longitudinal MRI study","volume":"2","author":"Giedd","year":"1999","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbr.2026.116361_bib3","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1001\/archpsyc.62.6.593","article-title":"Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the national comorbidity survey replication","volume":"62","author":"Kessler","year":"2005","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.bbr.2026.116361_bib4","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.biopsych.2024.01.026","article-title":"Transcriptional patterns of brain structural covariance network abnormalities associated with suicidal thoughts and behaviors in major depressive disorder","volume":"96","author":"Qin","year":"2024","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbr.2026.116361_bib5","doi-asserted-by":"crossref","unstructured":"Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990\u20132019: a systematic analysis for the Global Burden of Disease Study 2019, The Lancet Psychiatry 9 (2022) 137\u2013150. https:\/\/doi.org\/10.1016\/S2215-0366(21)00395-3.","DOI":"10.1016\/S2215-0366(21)00395-3"},{"key":"10.1016\/j.bbr.2026.116361_bib6","unstructured":"K. Hawton, K.E.A. Saunders, R.C. O\u2019Connor, Suicide 1 Self-harm and suicide in adolescents, (n.d.)."},{"key":"10.1016\/j.bbr.2026.116361_bib7","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/S0140-6736(09)60741-8","article-title":"Global patterns of mortality in young people: a systematic analysis of population health data","volume":"374","author":"Patton","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.bbr.2026.116361_bib8","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1176\/appi.ajp.2014.14020138","article-title":"The NIMH Research Domain Criteria (RDoC) project: precision medicine for psychiatry","volume":"171","author":"Insel","year":"2014","journal-title":"AJP"},{"key":"10.1016\/j.bbr.2026.116361_bib9","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1038\/nrn2513","article-title":"Why do many psychiatric disorders emerge during adolescence?","volume":"9","author":"Paus","year":"2008","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.bbr.2026.116361_bib10","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.jad.2019.04.064","article-title":"Structural alterations of the brain preceded functional alterations in major depressive disorder patients: evidence from multimodal connectivity","volume":"253","author":"Yao","year":"2019","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.bbr.2026.116361_bib11","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2024.1491042","article-title":"Functional connectivity density of different suicidal behaviors in adolescents with major depressive disorders","volume":"15","author":"Zhong","year":"2024","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.bbr.2026.116361_bib12","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1186\/s12888-019-2149-9","article-title":"Brain network alterations in individuals with and without mild cognitive impairment: parallel independent component analysis of AV1451 and AV45 positron emission tomography","volume":"19","author":"Li","year":"2019","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.bbr.2026.116361_bib13","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.tics.2011.08.003","article-title":"Large-scale brain networks and psychopathology: a unifying triple network model","volume":"15","author":"Menon","year":"2011","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.bbr.2026.116361_bib14","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1001\/jamapsychiatry.2015.0071","article-title":"Large-scale network dysfunction in major depressive disorder: a meta-analysis of resting-state functional connectivity","volume":"72","author":"Kaiser","year":"2015","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.bbr.2026.116361_bib15","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.jadohealth.2024.01.015","article-title":"Disrupted structural brain networks and structural-functional decoupling in first-episode drug-na\u00efve adolescent major depressive disorder","volume":"74","author":"Wu","year":"2024","journal-title":"J. Adolesc. Health"},{"key":"10.1016\/j.bbr.2026.116361_bib16","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1007\/s11682-018-0003-1","article-title":"Morphological changes in subregions of hippocampus and amygdala in major depressive disorder patients","volume":"14","author":"Yao","year":"2020","journal-title":"Brain Imaging Behav."},{"key":"10.1016\/j.bbr.2026.116361_bib17","doi-asserted-by":"crossref","first-page":"2096","DOI":"10.1016\/j.clinph.2019.08.009","article-title":"Altered dynamic functional connectivity in weakly-connected state in major depressive disorder","volume":"130","author":"Yao","year":"2019","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.bbr.2026.116361_bib18","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1038\/s44220-024-00309-y","article-title":"A mega-analysis of functional connectivity and network abnormalities in youth depression","volume":"2","author":"Tse","year":"2024","journal-title":"Nat. Ment. Health"},{"key":"10.1016\/j.bbr.2026.116361_bib19","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.biopsych.2014.09.002","article-title":"Emotion-dependent functional connectivity of the default mode network in adolescent depression","volume":"78","author":"Ho","year":"2015","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbr.2026.116361_bib20","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.tics.2017.11.002","article-title":"Large-scale gradients in human cortical organization","volume":"22","author":"Huntenburg","year":"2018","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.bbr.2026.116361_bib21","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1038\/s41467-019-08944-1","article-title":"Atypical functional connectome hierarchy in autism","volume":"10","author":"Hong","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbr.2026.116361_bib22","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1093\/brain\/121.6.1013","article-title":"From sensation to cognition","volume":"121","author":"Mesulam","year":"1998","journal-title":"Brain"},{"key":"10.1016\/j.bbr.2026.116361_bib23","doi-asserted-by":"crossref","first-page":"12574","DOI":"10.1073\/pnas.1608282113","article-title":"Situating the default-mode network along a principal gradient of macroscale cortical organization","volume":"113","author":"Margulies","year":"2016","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.bbr.2026.116361_bib24","doi-asserted-by":"crossref","first-page":"10649","DOI":"10.1523\/JNEUROSCI.0759-12.2012","article-title":"Stepwise connectivity of the modal cortex reveals the multimodal organization of the human brain","volume":"32","author":"Sepulcre","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbr.2026.116361_bib25","doi-asserted-by":"crossref","first-page":"2666","DOI":"10.1002\/hbm.23552","article-title":"Emergence of a hierarchical brain during infancy reflected by stepwise functional connectivity","volume":"38","author":"Pendl","year":"2017","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.bbr.2026.116361_bib26","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3000284","article-title":"Microstructural and functional gradients are increasingly dissociated in transmodal cortices","volume":"17","author":"Paquola","year":"2019","journal-title":"PLoS Biol."},{"key":"10.1016\/j.bbr.2026.116361_bib27","doi-asserted-by":"crossref","first-page":"2544","DOI":"10.1002\/hbm.22790","article-title":"Sensation-to-cognition cortical streams in attention-deficit\/hyperactivity disorder","volume":"36","author":"Carmona","year":"2015","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.bbr.2026.116361_bib28","doi-asserted-by":"crossref","first-page":"4645","DOI":"10.1002\/hbm.24727","article-title":"Stepwise functional connectivity reveals altered sensory-multimodal integration in medication-na\u00efve adults with attention deficit hyperactivity disorder","volume":"40","author":"Pretus","year":"2019","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.bbr.2026.116361_bib29","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/s12021-016-9299-4","article-title":"DPABI: data processing & analysis for (Resting-State) brain imaging","volume":"14","author":"Yan","year":"2016","journal-title":"Neuroinform"},{"key":"10.1016\/j.bbr.2026.116361_bib30","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.neuroimage.2012.08.052","article-title":"An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data","volume":"64","author":"Satterthwaite","year":"2013","journal-title":"NeuroImage"},{"key":"10.1016\/j.bbr.2026.116361_bib31","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.neuroimage.2017.03.020","article-title":"Benchmarking of participant-level confound regression strategies for the control of motion artifact in studies of functional connectivity","volume":"154","author":"Ciric","year":"2017","journal-title":"NeuroImage"},{"key":"10.1016\/j.bbr.2026.116361_bib32","doi-asserted-by":"crossref","first-page":"3095","DOI":"10.1093\/cercor\/bhx179","article-title":"Local-global parcellation of the human cerebral cortex from intrinsic functional connectivity MRI","volume":"28","author":"Schaefer","year":"2018","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.bbr.2026.116361_bib33","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.acha.2006.04.006","article-title":"Diffusion maps","volume":"21","author":"Coifman","year":"2006","journal-title":"Appl. Comput. Harmon. Anal."},{"key":"10.1016\/j.bbr.2026.116361_bib34","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/s42003-020-0794-7","article-title":"BrainSpace: a toolbox for the analysis of macroscale gradients in neuroimaging and connectomics datasets","volume":"3","author":"Vos De Wael","year":"2020","journal-title":"Commun. Biol."}],"container-title":["Behavioural Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432826003372?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432826003372?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T16:44:16Z","timestamp":1786553056000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166432826003372"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":34,"alternative-id":["S0166432826003372"],"URL":"https:\/\/doi.org\/10.1016\/j.bbr.2026.116361","relation":{},"ISSN":["0166-4328"],"issn-type":[{"value":"0166-4328","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Complementary functional gradient and SFC analyses reveal network abnormalities in adolescent depression subtypes","name":"articletitle","label":"Article Title"},{"value":"Behavioural Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbr.2026.116361","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116361"}}