{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T21:53:51Z","timestamp":1791323631193,"version":"4.3.1"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["No.30873057"],"award-info":[{"award-number":["No.30873057"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["11JC1406600"],"award-info":[{"award-number":["11JC1406600"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Behavioural Brain Research"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.bbr.2026.116439","type":"journal-article","created":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T14:27:18Z","timestamp":1788100038000},"page":"116439","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["N-stearoyltyrosine attenuates ischemia\u2013reperfusion injury by inhibiting caspase-dependent apoptosis and PARP-1\/AIF\u2013mediated parthanatos"],"prefix":"10.1016","volume":"516","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9467-7789","authenticated-orcid":false,"given":"Rui","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6475-1717","authenticated-orcid":false,"given":"Kejia","family":"Le","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbr.2026.116439_bib1","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1002\/med.21817","article-title":"Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications","volume":"42","author":"Tuo","year":"2022","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.bbr.2026.116439_bib2","doi-asserted-by":"crossref","first-page":"e331","DOI":"10.1161\/STROKEAHA.108.531632","article-title":"Apoptotic mechanisms after cerebral ischemia","volume":"40","author":"Broughton","year":"2009","journal-title":"Stroke"},{"key":"10.1016\/j.bbr.2026.116439_bib3","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1007\/s10495-023-01824-6","article-title":"Anti-apoptosis effect of traditional Chinese medicine in the treatment of cerebral ischemia-reperfusion injury","volume":"28","author":"Zhao","year":"2023","journal-title":"Apoptosis"},{"key":"10.1016\/j.bbr.2026.116439_bib4","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1007\/s12035-012-8299-0","article-title":"Anandamide and 2-arachidonoylglycerol: pharmacological properties, functional features, and emerging specificities of the two major endocannabinoids","volume":"46","author":"Luchicchi","year":"2012","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.bbr.2026.116439_bib5","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0022-3565(24)36812-0","article-title":"The biodisposition and metabolism of anandamide in mice","volume":"282","author":"Willoughby","year":"1997","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.bbr.2026.116439_bib6","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.jphs.2016.08.009","article-title":"Dipotassium N-stearoyltyrosinate ameliorated pathological injuries in triple-transgenic mouse model of Alzheimer's disease","volume":"132","author":"Liu","year":"2016","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.bbr.2026.116439_bib7","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.brainres.2010.02.037","article-title":"Neuroprotective effects of NSTyr on cognitive function and neuronal plasticity in rats of chronic cerebral hypoperfusion","volume":"1325","author":"Lin","year":"2010","journal-title":"Brain Res."},{"key":"10.1016\/j.bbr.2026.116439_bib8","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.lfs.2015.01.012","article-title":"N-Stearoyltyrosine protects primary cortical neurons against A\u03b2(1-40)-induced injury through inhibiting endocannabinoid degradation","volume":"124","author":"Cui","year":"2015","journal-title":"Life Sci."},{"key":"10.1016\/j.bbr.2026.116439_bib9","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1254\/jphs.13184FP","article-title":"N-stearoyltyrosine protects against glutamate-induced oxidative toxicity by an apoptosis-inducing factor (AIF)-mediated caspase-independent cell death pathway","volume":"124","author":"Yang","year":"2014","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.bbr.2026.116439_bib10","doi-asserted-by":"crossref","first-page":"4051","DOI":"10.3390\/molecules14104051","article-title":"Synthesis of Lipoamino acids and their activity against cerebral ischemic injury","volume":"14","author":"Yao","year":"2009","journal-title":"Molecules"},{"key":"10.1016\/j.bbr.2026.116439_bib11","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1161\/01.STR.20.1.84","article-title":"Reversible middle cerebral artery occlusion without craniectomy in rats","volume":"20","author":"Longa","year":"1989","journal-title":"Stroke"},{"key":"10.1016\/j.bbr.2026.116439_bib12","doi-asserted-by":"crossref","first-page":"475","DOI":"10.3389\/fncel.2018.00475","article-title":"TAT-Ngn2 enhances cognitive function recovery and regulates caspase-dependent and mitochondrial apoptotic pathways after experimental stroke","volume":"12","author":"Zhao","year":"2018","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.bbr.2026.116439_bib13","doi-asserted-by":"crossref","DOI":"10.1126\/science.aad6872","article-title":"A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1","volume":"354","author":"Wang","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.bbr.2026.116439_bib14","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.brainres.2009.06.070","article-title":"Neuroprotective effects of N-stearoyltyrosine on transient global cerebral ischemia in gerbils","volume":"1287","author":"Zhang","year":"2009","journal-title":"Brain Res."},{"key":"10.1016\/j.bbr.2026.116439_bib15","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1038\/s41580-023-00689-6","article-title":"A guide to cell death pathways","volume":"25","author":"Yuan","year":"2024","journal-title":"Nat. Rev. Mol. Cell. Biol."},{"key":"10.1016\/j.bbr.2026.116439_bib16","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/s41580-018-0089-8","article-title":"Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins","volume":"20","author":"Singh","year":"2019","journal-title":"Nat. Rev. Mol. Cell. Biol."},{"key":"10.1016\/j.bbr.2026.116439_bib17","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/s41419-020-2280-z","article-title":"Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice","volume":"11","author":"Li","year":"2020","journal-title":"Cell. Death Dis."},{"key":"10.1016\/j.bbr.2026.116439_bib18","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.semcdb.2016.11.007","article-title":"Poly(ADP-ribose)polymerase-1 hyperactivation in neurodegenerative diseases: the death knell tolls for neurons","volume":"63","author":"Narne","year":"2017","journal-title":"Semin. Cell. Dev. Biol."},{"key":"10.1016\/j.bbr.2026.116439_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2024.176724","article-title":"Mangiferin alleviated poststroke cognitive impairment by modulating lipid metabolism in cerebral ischemia\/reperfusion rats","volume":"977","author":"Zhang","year":"2024","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bbr.2026.116439_bib20","doi-asserted-by":"crossref","DOI":"10.2174\/0118715273418707251202102848","article-title":"SIRT1: an emerging role in regulated cell death in ischemic stroke","author":"Zhou","year":"2026","journal-title":"CNS Neurol. Disord. Drug. Targets"},{"key":"10.1016\/j.bbr.2026.116439_bib21","series-title":"The Preclinical Pharmacokinetics Studies of Novel Neuroprotective Agent N-stearoyltyrosine","author":"Le","year":"2013"},{"key":"10.1016\/j.bbr.2026.116439_bib22","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.neures.2017.04.019","article-title":"N-stearoyltyrosine protects primary cortical neurons against oxygen-glucose deprivation-induced apoptosis through inhibiting anandamide inactivation system","volume":"123","author":"Cui","year":"2017","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.bbr.2026.116439_bib23","doi-asserted-by":"crossref","first-page":"205","DOI":"10.4103\/1673-5374.290875","article-title":"Role of apoptosis-inducing factor in perinatal hypoxic-ischemic brain injury","volume":"16","author":"Rodriguez","year":"2021","journal-title":"Neural Regen. Res."},{"key":"10.1016\/j.bbr.2026.116439_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155817","article-title":"B. glomerulata promotes neuroprotection against ischemic stroke by inhibiting apoptosis through the activation of PI3K\/AKT\/mTOR pathway","volume":"132","author":"Xu","year":"2024","journal-title":"Phytomedicine"},{"key":"10.1016\/j.bbr.2026.116439_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2022.e12278","article-title":"Up-regulation of Sirtuin-1\/autophagy signaling in human cerebral ischemia: possible role in caspase-3 mediated apoptosis","volume":"8","author":"Teertam","year":"2022","journal-title":"Heliyon"},{"key":"10.1016\/j.bbr.2026.116439_bib26","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1186\/s12964-025-02272-2","article-title":"Apoptosis-inducing factor (AIF) at the crossroad of cell survival and cell death: implications for cancer and mitochondrial diseases","volume":"23","author":"Nguyen","year":"2025","journal-title":"Cell. Commun. Signal."},{"key":"10.1016\/j.bbr.2026.116439_bib27","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1007\/s10495-020-01600-w","article-title":"Baicalein attenuates caspase-independent cells death via inhibiting PARP-1 activation and AIF nuclear translocation in cerebral ischemia\/reperfusion rats","volume":"25","author":"Li","year":"2020","journal-title":"Apoptosis"},{"key":"10.1016\/j.bbr.2026.116439_bib28","doi-asserted-by":"crossref","first-page":"10262","DOI":"10.1523\/JNEUROSCI.2818-05.2005","article-title":"Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia","volume":"25","author":"Culmsee","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbr.2026.116439_bib29","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1152\/physrev.00058.2021","article-title":"Mitochondria in health, disease, and aging","volume":"103","author":"Harrington","year":"2023","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bbr.2026.116439_bib30","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.scib.2024.06.005","article-title":"CSF multi-omics of intracerebral hemorrhage from onset to reperfusion underscores lipid metabolism in functional outcome","volume":"70","author":"Jiang","year":"2025","journal-title":"Sci. Bull. (Beijing)"},{"key":"10.1016\/j.bbr.2026.116439_bib31","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s43556-025-00284-5","article-title":"Role of mitochondria in physiological activities, diseases, and therapy","volume":"6","author":"Wang","year":"2025","journal-title":"Mol. Biomed."},{"key":"10.1016\/j.bbr.2026.116439_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2025.103868","article-title":"Role of mitochondria transmission in ischemic stroke: Friend or foe?","volume":"87","author":"Yang","year":"2025","journal-title":"Redox Biol."},{"key":"10.1016\/j.bbr.2026.116439_bib33","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/s41418-020-00654-2","article-title":"Neuronal cell life, death, and axonal degeneration as regulated by the BCL-2 family proteins","volume":"28","author":"Pemberton","year":"2021","journal-title":"Cell. Death Differ."},{"key":"10.1016\/j.bbr.2026.116439_bib34","doi-asserted-by":"crossref","first-page":"2972","DOI":"10.1038\/s12276-025-01605-y","article-title":"Optogenetic engineering of BAX to control mitochondrial permeabilization and attenuate apoptosis in cells","volume":"57","author":"Lee","year":"2025","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.bbr.2026.116439_bib35","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s00018-023-04824-6","article-title":"Activity-dependent regulation of the BAX\/BCL-2 pathway protects cortical neurons from apoptotic death during early development","volume":"80","author":"Schroer","year":"2023","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bbr.2026.116439_bib36","doi-asserted-by":"crossref","first-page":"487","DOI":"10.4196\/kjpp.24.293","article-title":"Melittin inhibits MPP(+)-induced HT22 cell death by suppressing Bax activation and improving mitochondrial function","volume":"29","author":"Yu","year":"2025","journal-title":"Korean J. Physiol. Pharmacol."},{"key":"10.1016\/j.bbr.2026.116439_bib37","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.24976\/Discov.Med.202537200.164","article-title":"Galectin-3 Preserves Intestinal Barrier Function via Regulation of the JAK2\/STAT3 Signaling Pathway During Ischemia-Reperfusion Injury in Mice","volume":"37","author":"Yu","year":"2025","journal-title":"Discov. Med."},{"key":"10.1016\/j.bbr.2026.116439_bib38","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.tips.2021.11.001","article-title":"Physiological and pharmacological modulation of BAX","volume":"43","author":"Spitz","year":"2022","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.bbr.2026.116439_bib39","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.24976\/Discov.Med.202537200.171","article-title":"Galectin-3 Mediates Ischemia-Reperfusion Injury Through Regulation of Oxidative Stress, Inflammation, and the TFAM\/PPAR\u03b2 Axis","volume":"37","author":"Liu","year":"2025","journal-title":"Discov. Med."},{"key":"10.1016\/j.bbr.2026.116439_bib40","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1111\/jnc.15464","article-title":"Emerging role of PARP-1 and PARthanatos in ischemic stroke","volume":"160","author":"Liu","year":"2022","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbr.2026.116439_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2023.106314","article-title":"Poly (ADP-Ribose) polymerase 1 and parthanatos in neurological diseases: from pathogenesis to therapeutic opportunities","volume":"187","author":"Xu","year":"2023","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.bbr.2026.116439_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2024.116174","article-title":"Parthanatos: Mechanisms, modulation, and therapeutic prospects in neurodegenerative disease and stroke","volume":"228","author":"Yang","year":"2024","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bbr.2026.116439_bib43","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1126\/science.1072221","article-title":"Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor","volume":"297","author":"Yu","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.bbr.2026.116439_bib44","doi-asserted-by":"crossref","first-page":"18308","DOI":"10.1073\/pnas.0606526103","article-title":"Poly(ADP-ribose) (PAR) polymer is a death signal","volume":"103","author":"Andrabi","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbr.2026.116439_bib45","doi-asserted-by":"crossref","first-page":"ra20","DOI":"10.1126\/scisignal.2000902","article-title":"Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos)","volume":"4","author":"Wang","year":"2011","journal-title":"Sci. Signal."},{"key":"10.1016\/j.bbr.2026.116439_bib46","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1111\/1440-1681.12757","article-title":"Neuroprotective effects of a novel poly (ADP-ribose) polymerase-1 inhibitor, JPI-289, in hypoxic rat cortical neurons","volume":"44","author":"Kim","year":"2017","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.bbr.2026.116439_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2024.176377","article-title":"PARP-1 inhibitor alleviates cerebral ischemia\/reperfusion injury by reducing PARylation of HK-1 and LDH in mice","volume":"967","author":"Chen","year":"2024","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bbr.2026.116439_bib48","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.actbio.2021.12.023","article-title":"Targeted delivery of PARP inhibitors to neuronal mitochondria via biomimetic engineered nanosystems in a mouse model of traumatic brain injury","volume":"140","author":"Sun","year":"2022","journal-title":"Acta Biomater."},{"key":"10.1016\/j.bbr.2026.116439_bib49","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.1111\/bph.12416","article-title":"Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities","volume":"171","author":"Fatokun","year":"2014","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bbr.2026.116439_bib50","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2021.662034","article-title":"Targeting parthanatos in ischemic stroke","volume":"12","author":"Koehler","year":"2021","journal-title":"Front. Neurol."},{"key":"10.1016\/j.bbr.2026.116439_bib51","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.cbi.2017.05.009","article-title":"N-stearoyl-l-Tyrosine inhibits the cell senescence and apoptosis induced by H(2)O(2) in HEK293\/Tau cells via the CB2 receptor","volume":"272","author":"Hu","year":"2017","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.bbr.2026.116439_bib52","article-title":"Mitochondrial CB1 receptor is involved in ACEA-induced protective effects on neurons and mitochondrial functions","volume":"5","author":"Ma","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbr.2026.116439_bib53","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s13041-016-0257-8","article-title":"Acute upregulation of neuronal mitochondrial type-1 cannabinoid receptor and it's role in metabolic defects and neuronal apoptosis after TBI","volume":"9","author":"Xu","year":"2016","journal-title":"Mol. Brain"},{"key":"10.1016\/j.bbr.2026.116439_bib54","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1007\/s00204-020-02944-7","article-title":"Synthetic cannabinoid CP-55,940 induces apoptosis in a human skeletal muscle model via regulation of CB(1) receptors and L-type Ca(2+) channels","volume":"95","author":"Tomiyama","year":"2021","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.bbr.2026.116439_bib55","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s12975-022-01119-z","article-title":"Resveratrol preconditioning downregulates PARP1 Protein to Alleviate PARP1-mediated cell death following cerebral ischemia","volume":"15","author":"Jackson","year":"2024","journal-title":"Transl. Stroke Res."},{"key":"10.1016\/j.bbr.2026.116439_bib56","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24087106","article-title":"The Duration of Oxygen and Glucose Deprivation (OGD) determines the effects of subsequent reperfusion on rat pheochromocytoma (PC12) cells and primary cortical neurons","volume":"24","author":"Singh","year":"2023","journal-title":"Int. J. Mol. Sci."}],"container-title":["Behavioural Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432826004158?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166432826004158?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T21:43:11Z","timestamp":1791322991000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166432826004158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":56,"alternative-id":["S0166432826004158"],"URL":"https:\/\/doi.org\/10.1016\/j.bbr.2026.116439","relation":{},"ISSN":["0166-4328"],"issn-type":[{"value":"0166-4328","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"N-stearoyltyrosine attenuates ischemia\u2013reperfusion injury by inhibiting caspase-dependent apoptosis and PARP-1\/AIF\u2013mediated parthanatos","name":"articletitle","label":"Article Title"},{"value":"Behavioural Brain Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbr.2026.116439","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116439"}}