{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:28:58Z","timestamp":1790774938720,"version":"4.1.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2004,6]]},"DOI":"10.1016\/j.bbrc.2004.04.132","type":"journal-article","created":{"date-parts":[[2004,5,11]],"date-time":"2004-05-11T10:35:09Z","timestamp":1084271709000},"page":"992-997","source":"Crossref","is-referenced-by-count":33,"title":["A protective role for zinc on intestinal peroxidative damage during oral iron repletion"],"prefix":"10.1016","volume":"318","author":[{"given":"B","family":"Sreedhar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Subramaniyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.Madhavan","family":"Nair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2004.04.132_BIB1","first-page":"302","article-title":"The prevalence of anaemia in the world","volume":"38","author":"De Maeyer","year":"1985","journal-title":"World Health Stat. Quart."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB2","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/hep.1840110122","article-title":"The pathology of hepatic iron overload: a free radical-mediated process?","volume":"11","author":"Bacon","year":"1990","journal-title":"Hepatology"},{"key":"10.1016\/j.bbrc.2004.04.132_BIB3","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1172\/JCI110787","article-title":"Hepatic lipid peroxidation in vivo in rat with chronic iron overload","volume":"71","author":"Bacon","year":"1983","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB4","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1002\/hep.1840050514","article-title":"Hepatic mitochondrial oxidative stress in rats with chronic dietary iron overload","volume":"5","author":"Bacon","year":"1985","journal-title":"Hepatology"},{"key":"10.1016\/j.bbrc.2004.04.132_BIB5","unstructured":"T.J. Peters, M.J. O\u2019Connell, R.J. Ward, in: G. Poli, K.H. Cheeseman, M.U. Dianzani, T.R. Slater (Eds.), Free Radicals in Liver Injury, IRL, Oxford, pp. 100\u2013115"},{"key":"10.1016\/j.bbrc.2004.04.132_BIB6","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/S0891-5849(98)00086-0","article-title":"Iron-deficient intestine is more susceptible to peroxidative damage during iron supplementation in rats","volume":"25","author":"Srigirdhar","year":"1998","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB7","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1023\/A:1011023111048","article-title":"Oral repletion of iron induces free radical mediated alterations in the gastrointestinal tract of rat","volume":"219","author":"Srigiridhar","year":"2001","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB8","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1017\/S0007114500001392","article-title":"Supplementation with alpha-tocopherol or a combination of alpha-tocopherol and ascorbic acid protects the gastrointestinal tract of iron-deficient rats against iron-induced oxidative damage during iron repletion","volume":"84","author":"Srigiridhar","year":"2000","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB9","doi-asserted-by":"crossref","first-page":"1700S","DOI":"10.1093\/jn\/133.5.1700S","article-title":"Iron and oxidative stress in pregnancy","volume":"133","author":"Casanueva","year":"2003","journal-title":"J. Nutr."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB10","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0891-5849(90)90076-U","article-title":"The physiological role of zinc as an anti-oxidant","volume":"8","author":"Bray","year":"1990","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB11","first-page":"A723","article-title":"Zinc deficiency associated alterations in the chemotactic and respiratory burst responses of rat peripheral blood neutrophils","volume":"7","author":"Sakanashi","year":"1993","journal-title":"FASEB J."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB12","first-page":"A346","article-title":"Extracellular superoxide dismutase activity: a promising indicator of zinc status in humans","volume":"12","author":"Davis","year":"1998","journal-title":"FASEB J."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB13","first-page":"238","article-title":"Absorption, transport, and hepatic metabolism of copper and zinc: special reference to metallothionein and ceruloplasmin","volume":"65","author":"Cousins","year":"1985","journal-title":"Phys. Rev."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB14","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1093\/jn\/123.11.1939","article-title":"AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition Ad Hoc writing committee on the reformulation of the AIN-76A rodent diet","volume":"123","author":"Reeves","year":"1993","journal-title":"J. Nutr."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB15","series-title":"Practical Haematology","first-page":"31","article-title":"Estimation of haemoglobin","author":"Dacie","year":"1975"},{"key":"10.1016\/j.bbrc.2004.04.132_BIB16","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/0003-2697(73)90523-X","article-title":"A simplified method for the quantitative assay of small amounts of protein in biologic material","volume":"51","author":"Schacterle","year":"1973","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB17","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1016\/S0021-9258(18)96082-5","article-title":"Mechanism of aconitase action. I. The hydrogen transfer reaction","volume":"242","author":"Rose","year":"1967","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB18","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1006\/jmrb.1994.1062","article-title":"Simulation of multiple isotropic spin-trap EPR spectra","volume":"104","author":"Duling","year":"1994","journal-title":"J. Mag. Reson. Series B"},{"key":"10.1016\/j.bbrc.2004.04.132_BIB19","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1038\/41343","article-title":"Cloning and characterization of a mammalian proton-coupled metal-ion transporter","volume":"388","author":"Gunshin","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2004.04.132_BIB20","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1093\/jn\/127.1.177","article-title":"Iron uptake by isolated human enterocyte suspensions in vitro is dependent on body iron stores and inhibited by other metal cations","volume":"127","author":"Goddard","year":"1997","journal-title":"J. Nutr."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB21","first-page":"24252","article-title":"The role of iron in the activation\u2013inactivation of aconitase","volume":"269","author":"Kennedy","year":"1983","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB22","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1093\/jn\/127.2.238","article-title":"Dietary iron intake modulates the activity of iron regulatory proteins and the abundance of ferritin and m-aconitase in rat liver","volume":"127","author":"Chen","year":"1997","journal-title":"J. Nutr."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB23","doi-asserted-by":"crossref","first-page":"28875","DOI":"10.1074\/jbc.272.46.28875","article-title":"Zinc inhibition of mitochondrial aconitase and its importance in citrate metabolism of prostate epithelial cells","volume":"272","author":"Costello","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB24","doi-asserted-by":"crossref","first-page":"19328","DOI":"10.1016\/S0021-9258(18)55001-8","article-title":"Superoxide sensitivity of Escherichia coli aconitase","volume":"266","author":"Gardner","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB25","doi-asserted-by":"crossref","first-page":"14064","DOI":"10.1074\/jbc.275.19.14064","article-title":"Mitochondrial aconitase is a source of hydroxyl radical. An electron spin resonance investigation","volume":"275","author":"Vasquez-vivar","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB26","doi-asserted-by":"crossref","first-page":"33585","DOI":"10.1074\/jbc.M003890200","article-title":"Doxorubicin-induced apoptosis in endothelial cells and cardiomyocetes is ameliorated by nitrone spin traps and ebselen","volume":"275","author":"Srigiridhar","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB27","doi-asserted-by":"crossref","first-page":"13399","DOI":"10.1074\/jbc.270.22.13399","article-title":"Superoxide radical andiron modulate aconitase activity in mammalian cells","volume":"270","author":"Gardner","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB28","first-page":"402","article-title":"Protective effects of anti-oxidant enzymes and GSH in vivo on iron mediated lipid peroxidation in gastrointestinal tract of rat","volume":"34","author":"Srigiridhar","year":"1997","journal-title":"Ind. J. Biochem. Biophys."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB29","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0006-2952(99)00301-9","article-title":"Regulation of metallothionein gene expression by oxidative stress and metal ions","volume":"59","author":"Andrews","year":"2000","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB30","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1007\/978-3-0348-6784-9_63","article-title":"Alterations of radiosensitivity in metallothionein-induced mice and a possible role of Zn\u2013Cu thionein in glutathione peroxidase system","volume":"52","author":"Matsubara","year":"1987","journal-title":"Exp. Suppl."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB31","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0006-2952(98)00099-9","article-title":"Induction of anti-oxidants by adriamycin in mouse heart","volume":"56","author":"Yin","year":"1998","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bbrc.2004.04.132_BIB32","doi-asserted-by":"crossref","first-page":"8440","DOI":"10.1073\/pnas.88.19.8440","article-title":"Direct evidence for in vivo hydroxyl-radical generation in experimental iron overload: an ESR spin-trapping investigation","volume":"88","author":"Burkitt","year":"1991","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2004.04.132_BIB33","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1172\/JCI118205","article-title":"Iron supplementation generates hydroxyl radical in vivo. An ESR spin-trapping investigation","volume":"96","author":"Kadiiska","year":"1995","journal-title":"J. Clin. Invest."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X04008940?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X04008940?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,6,17]],"date-time":"2021-06-17T12:40:48Z","timestamp":1623933648000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X04008940"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2004,6]]}},"alternative-id":["S0006291X04008940"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2004.04.132","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2004,6]]}}}