{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T03:08:24Z","timestamp":1791169704210,"version":"4.1.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2004,11,1]],"date-time":"2004-11-01T00:00:00Z","timestamp":1099267200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2004,11]]},"DOI":"10.1016\/j.bbrc.2004.09.080","type":"journal-article","created":{"date-parts":[[2004,9,28]],"date-time":"2004-09-28T11:28:19Z","timestamp":1096370899000},"page":"534-546","source":"Crossref","is-referenced-by-count":61,"title":["Human bronchial epithelial cells express and secrete MMP-12"],"prefix":"10.1016","volume":"324","author":[{"given":"Mark C.","family":"Lavigne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paresh","family":"Thakker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Gunn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joy S.","family":"Miyashiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aeona M.","family":"Wasserman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shui-Qing","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey W.","family":"Pelker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiko","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Eppihimer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2004.09.080_bib1","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1046\/j.1365-2222.1998.028s5071.x","article-title":"Inflammatory mechanisms in childhood asthma","volume":"28","author":"Warner","year":"1998","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.bbrc.2004.09.080_bib2","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/S0955-0674(00)00248-9","article-title":"Matrix metalloproteinases: they\u2019re not just for matrix anymore!","volume":"13","author":"McCawley","year":"2001","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.bbrc.2004.09.080_bib3","doi-asserted-by":"crossref","first-page":"9249","DOI":"10.1021\/bi00028a038","article-title":"Neutrophil elastase processing of gelatinase A is mediated by extracellular matrix","volume":"34","author":"Rice","year":"1995","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbrc.2004.09.080_bib4","doi-asserted-by":"crossref","first-page":"17119","DOI":"10.1074\/jbc.271.29.17119","article-title":"The soluble catalytic domain on membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. Regulation by TIMP-1 and TIMP-3","volume":"271","author":"Will","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2004.09.080_bib5","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1042\/bj2770277","article-title":"Matrix metalloproteinase degradation of elastin, type IV collagen, and proteoglycan. A quantitative comparison of the activities of 95 and 72kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP)","volume":"277","author":"Murphy","year":"1991","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbrc.2004.09.080_bib6","doi-asserted-by":"crossref","first-page":"7870","DOI":"10.1016\/S0021-9258(20)89530-1","article-title":"Human 92- and 72-kilodalton type IV collagenases are elastases","volume":"266","author":"Senior","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2004.09.080_bib7","doi-asserted-by":"crossref","first-page":"3719","DOI":"10.1242\/jcs.00063","article-title":"Metalloproteinase inhibitors: biological actions and therapeutic opportunities","volume":"115","author":"Baker","year":"2002","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bbrc.2004.09.080_bib8","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1126\/science.277.5334.2002","article-title":"Macrophage elastase is required for cigarette-smoke-induced emphysema in mice","volume":"277","author":"Hautamaki","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2004.09.080_bib9","doi-asserted-by":"crossref","first-page":"23824","DOI":"10.1016\/S0021-9258(20)80459-1","article-title":"Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages","volume":"268","author":"Shapiro","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2004.09.080_bib10","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0091-6749(00)90066-6","article-title":"Epithelial-mesenchymal interactions in the pathogenesis of asthma","volume":"105","author":"Holgate","year":"2000","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.bbrc.2004.09.080_bib11","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1165\/ajrcmb.14.1.8534481","article-title":"Mucociliary differentiation of serially passaged normal human tracheobronchial epithelial cells","volume":"14","author":"Gray","year":"1996","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.bbrc.2004.09.080_bib12","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1165\/ajrcmb.13.1.7541219","article-title":"Modulation of fibronectin and tenascin production in human bronchial epithelial cells by inflammatory cytokines in vitro","volume":"13","author":"Harkonen","year":"1995","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.bbrc.2004.09.080_bib13","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1165\/ajrcmb.18.1.2740","article-title":"Stimulation of migration and wound repair of guinea-pig airway epithelial cells in response to epidermal growth factor","volume":"18","author":"Kim","year":"1998","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.bbrc.2004.09.080_bib14","doi-asserted-by":"crossref","first-page":"L39","DOI":"10.1152\/ajplung.2001.280.1.L39","article-title":"Overexpression of tumor necrosis factor-\u03b1 produces an increase in lung volumes and pulmonary hypertension","volume":"280","author":"Fujita","year":"2001","journal-title":"Am. J. Physiol. (Lung Cell. Mol. Physiol.)"},{"key":"10.1016\/j.bbrc.2004.09.080_bib15","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1046\/j.1365-2222.2003.01593.x","article-title":"The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma","volume":"33","author":"Hamilton","year":"2003","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.bbrc.2004.09.080_bib16","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/j.1365-2222.1993.tb00317.x","article-title":"The potential role of tumour necrosis factor alpha in asthma","volume":"23","author":"Kips","year":"1993","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.bbrc.2004.09.080_bib17","doi-asserted-by":"crossref","first-page":"L165","DOI":"10.1152\/ajplung.2001.280.1.L165","article-title":"Activation of epidermal growth factor receptors is responsible for mucin synthesis induced by cigarette smoke","volume":"280","author":"Takeyama","year":"2001","journal-title":"Am. J. Physiol. (Lung Cell. Mol. Physiol.)"},{"key":"10.1016\/j.bbrc.2004.09.080_bib18","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1084\/jem.192.11.1587","article-title":"Interferon \u03b3 induction of pulmonary emphysema in the adult murine lung","volume":"192","author":"Wang","year":"2000","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.bbrc.2004.09.080_bib19","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1172\/JCI2182","article-title":"Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms","volume":"102","author":"Curci","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbrc.2004.09.080_bib20","doi-asserted-by":"crossref","first-page":"11400","DOI":"10.1073\/pnas.93.21.11400","article-title":"A stable human-derived packaging cell line for production of high titer retrovirus\/vesicular stomatitis virus G pseudotypes","volume":"93","author":"Ory","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2004.09.080_bib21","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/S1074-7613(00)80671-8","article-title":"Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism","volume":"9","author":"Ouyang","year":"1998","journal-title":"Immunity"},{"key":"10.1016\/j.bbrc.2004.09.080_bib22","doi-asserted-by":"crossref","first-page":"3081","DOI":"10.1073\/pnas.96.6.3081","article-title":"Epidermal growth factor system regulates mucin production in airways","volume":"96","author":"Takeyama","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2004.09.080_bib23","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1172\/JCI0214136","article-title":"Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling","volume":"110","author":"Lanone","year":"2002","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbrc.2004.09.080_bib24","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1165\/rcmb.2003-0051OC","article-title":"Interleukin-13-dependent expression of matrix metalloproteinase-12 is required for the development of airway eosinophilia in mice","volume":"30","author":"Pouladi","year":"2004","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.bbrc.2004.09.080_bib25","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1126\/science.282.5397.2261","article-title":"Requirement for IL-13 independently of IL-4 in experimental asthma","volume":"282","author":"Grunig","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2004.09.080_bib26","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1126\/science.282.5397.2258","article-title":"Interleukin-13: central mediator of allergic asthma","volume":"1282","author":"Wills-Karp","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2004.09.080_bib27","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1067\/mai.2003.139","article-title":"Chemokines in asthma: cooperative interaction between chemokines and IL-13","volume":"111","author":"Zimmermann","year":"2003","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.bbrc.2004.09.080_bib28","doi-asserted-by":"crossref","first-page":"7039","DOI":"10.4049\/jimmunol.169.12.7039","article-title":"IFN-gamma amplifies IL-6 and IL-8 responses by airway epithelial-like cells via indoleamine 2,3-dioxygenase","volume":"169","author":"van Wissen","year":"2002","journal-title":"J. Immunol."},{"key":"10.1016\/j.bbrc.2004.09.080_bib29","doi-asserted-by":"crossref","first-page":"11221","DOI":"10.1021\/bi960618e","article-title":"APMA (4-aminophenylmercuric acetate) activation of stromelysin-1 involves protein interactions in addition to those with cysteine-75 in the propeptide","volume":"35","author":"Galazka","year":"1996","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbrc.2004.09.080_bib30","first-page":"1963","article-title":"Active matrilysin (MMP-7) in human pterygia:potential role in angiogenesis","volume":"42","author":"Di Girolamo","year":"2001","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.bbrc.2004.09.080_bib31","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/0091-6749(92)90218-Q","article-title":"Cytokines in symptomatic asthmatic airways","volume":"89","author":"Broide","year":"1992","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.bbrc.2004.09.080_bib32","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1165\/rcmb.2002-0095OC","article-title":"Airway epithelial cells release MIP-3alpha\/CCL20 in response to cytokines and ambient particulate matter","volume":"28","author":"Reibman","year":"2003","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.bbrc.2004.09.080_bib33","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1007\/BF02621258","article-title":"Protein factors which regulate cell motility","volume":"25","author":"Rosen","year":"1989","journal-title":"In Vitro Cell. Dev. Biol."},{"key":"10.1016\/j.bbrc.2004.09.080_bib34","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1016\/S0002-9440(10)61150-9","article-title":"Renal fibrosis. Extracellular matrix microenvironment regulates migratory behavior of activated tubular epithelial cells","volume":"160","author":"Zeisberg","year":"2002","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.bbrc.2004.09.080_bib35","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1111\/j.1749-6632.1999.tb07712.x","article-title":"Balance between MMP-9 and TIMP-1 expressed by human bronchial epithelial cells: relevance to asthma","volume":"878","author":"Yao","year":"1999","journal-title":"Ann. N.Y. Acad. Sci."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X04021187?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X04021187?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,6,25]],"date-time":"2021-06-25T20:06:42Z","timestamp":1624651602000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X04021187"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,11]]},"references-count":35,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2004,11]]}},"alternative-id":["S0006291X04021187"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2004.09.080","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2004,11]]}}}