{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T20:01:59Z","timestamp":1760644919324},"reference-count":49,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2005,2]]},"DOI":"10.1016\/j.bbrc.2004.12.023","type":"journal-article","created":{"date-parts":[[2004,12,16]],"date-time":"2004-12-16T16:51:02Z","timestamp":1103215862000},"page":"424-430","source":"Crossref","is-referenced-by-count":7,"title":["Prostaglandin E2 down-regulation of cytochrome P-450 2B1 expression induced by phenobarbital is through EP2 receptor in rat hepatocytes"],"prefix":"10.1016","volume":"327","author":[{"given":"Chien-Chun","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui-Lan","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chong-Kuei","family":"Lii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai-Li","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaw-Ji","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haw-Wen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2004.12.023_bib1","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/0024-3205(92)90136-D","article-title":"Human cytochrome P-450 enzymes","volume":"50","author":"Guengerich","year":"1992","journal-title":"Life Sci."},{"key":"10.1016\/j.bbrc.2004.12.023_bib2","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0009-2797(00)00197-6","article-title":"Epoxide hydrolases: biochemistry and molecular biology","volume":"129","author":"Fretland","year":"2000","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.bbrc.2004.12.023_bib3","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1016\/S0006-2952(96)00560-6","article-title":"Regulation of gene expression of various phase I and phase II drug-metabolizing enzymes by tamoxifen in rat liver","volume":"52","author":"Hellriegel","year":"1996","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bbrc.2004.12.023_bib4","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0009-2797(00)00198-8","article-title":"Roles of glucuronidation and UDP-glucuronosyltransferases in xenobiotic bioactivation reactions","volume":"129","author":"Ritter","year":"2000","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.bbrc.2004.12.023_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00008571-199602000-00002","article-title":"P-450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature","volume":"6","author":"Nelson","year":"1996","journal-title":"Pharmacogenetics"},{"key":"10.1016\/j.bbrc.2004.12.023_bib6","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1146\/annurev.pa.34.040194.001343","article-title":"Regiochemistry of cytochrome P-450 isozymes","volume":"34","author":"Oguri","year":"1994","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.bbrc.2004.12.023_bib7","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/0163-7258(90)90030-6","article-title":"Enzyme induction in cytochrome P-450 system","volume":"45","author":"Okey","year":"1990","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.bbrc.2004.12.023_bib8","doi-asserted-by":"crossref","first-page":"3247","DOI":"10.1016\/S0021-9258(19)83611-6","article-title":"Phenobarbital induction of rat liver cytochromes P-450b and P-450e. Quantitation of specific RNAs by hybridization to synthetic oligodeoxyribonucleotide probes","volume":"260","author":"Omiecinski","year":"1985","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2004.12.023_bib9","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1080\/01635589709514621","article-title":"Amount and type of dietary lipid modulate rat hepatic cytochrome P-450 activity","volume":"29","author":"Chen","year":"1997","journal-title":"Nutr. Cancer"},{"key":"10.1016\/j.bbrc.2004.12.023_bib10","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1093\/jn\/129.11.1958","article-title":"Altered expression and glucocorticoid-inducibility of hepatic CYP3A and CYP2B enzymes in male rats fed diets containing soy protein isolate","volume":"129","author":"Ronis","year":"1999","journal-title":"J. Nutr."},{"key":"10.1016\/j.bbrc.2004.12.023_bib11","doi-asserted-by":"crossref","first-page":"12762","DOI":"10.1074\/jbc.270.21.12762","article-title":"cAMP-associated inhibition of phenobarbital-inducible cytochrome P450 gene expression in primary rat hepatocyte cultures","volume":"270","author":"Sidhu","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2004.12.023_bib12","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1016\/S0006-2952(99)00286-5","article-title":"EP4 receptor mediation of prostaglandin E2-stimulated mucus secretion by rabbit gastric epithelial cells","volume":"58","author":"Takahashi","year":"1999","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bbrc.2004.12.023_bib13","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/S0022-2143(02)00023-9","article-title":"Activation of prostaglandin E2-receptor EP2 and EP4 pathways induces growth inhibition in human gastric carcinoma cell lines","volume":"140","author":"Okuyama","year":"2002","journal-title":"J. Lab. Clin. Med."},{"key":"10.1016\/j.bbrc.2004.12.023_bib14","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1080\/01635581.2001.9680631","article-title":"Prostaglandin E2 is involved in the increase of cytochrome P-450 2B1 expression by \u03b1-tocopheryl succinate in primary rat hepatocytes in the presence of phenobarbital","volume":"41","author":"Tsai","year":"2001","journal-title":"Nutr. Cancer"},{"key":"10.1016\/j.bbrc.2004.12.023_bib15","doi-asserted-by":"crossref","first-page":"F152","DOI":"10.1152\/ajprenal.00287.2003","article-title":"Inhibition of nNOS expression in the macula densa by COX-2 derived prostaglandin E2","volume":"287","author":"Paliege","year":"2004","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.bbrc.2004.12.023_bib16","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1600-0765.1999.tb02228.x","article-title":"Prostaglandin E2and I2 regulate intercellular adhesion molecule-1 expression in interleukin-1 beta-stimulated human gingival fibroblasts","volume":"34","author":"Iwasaki","year":"1999","journal-title":"J. Periodontal Res."},{"key":"10.1016\/j.bbrc.2004.12.023_bib17","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1038\/sj.onc.1207295","article-title":"Regulation of HER-2 oncogene expression by cyclooxygenase-2 and prostaglandin E2","volume":"23","author":"Benoit","year":"2004","journal-title":"Oncogene"},{"key":"10.1016\/j.bbrc.2004.12.023_bib18","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.lfs.2003.09.031","article-title":"EP2 and EP4 prostanoid receptor signaling","volume":"74","author":"Regan","year":"2003","journal-title":"Life Sci."},{"key":"10.1016\/j.bbrc.2004.12.023_bib19","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1006\/bbrc.1994.1596","article-title":"Molecular cloning and expression of rat prostaglandin E receptor EP2 subtype","volume":"200","author":"Sando","year":"1994","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2004.12.023_bib20","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1006\/bbrc.1993.1904","article-title":"Molecular cloning and intrarenal localization of rat prostaglandin EP2 receptor EP3 subtype","volume":"194","author":"Takeuchi","year":"1993","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2004.12.023_bib21","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/0014-5793(95)00421-5","article-title":"Identification of prostaglandin E receptor \u2018EP2\u2019 cloned from mastocytoma cells as EP4 subtype","volume":"364","author":"Nishigaki","year":"1995","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbrc.2004.12.023_bib22","first-page":"29","article-title":"Preparation of isolated rat liver cells","volume":"13","author":"Seglen","year":"1976","journal-title":"Methods Biol."},{"key":"10.1016\/j.bbrc.2004.12.023_bib23","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/S0006-2952(99)00189-6","article-title":"Lack of modulation by phenobarbital of cyclic AMP levels or protein kinase A activity in rat primary hepatocytes","volume":"58","author":"Beck","year":"1999","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bbrc.2004.12.023_bib24","doi-asserted-by":"crossref","first-page":"3103","DOI":"10.1074\/jbc.272.5.3103","article-title":"Extracellular ATP induces anchorage-independent expression of cyclin A and rescues the transformed phenotype of a ras-resistant mutant cell line","volume":"272","author":"Yang","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2004.12.023_bib25","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2004.12.023_bib26","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1146\/annurev.bi.56.070187.003031","article-title":"Protein serine\/threonine kinases","volume":"56","author":"Edelman","year":"1987","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.bbrc.2004.12.023_bib27","first-page":"193","article-title":"The role of cyclic-AMP in cell proliferation: a critical assessment of the evidence","volume":"15","author":"Boynton","year":"1983","journal-title":"Adv. Cyclic Nucleotide Res."},{"key":"10.1016\/j.bbrc.2004.12.023_bib28","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1146\/annurev.biochem.66.1.807","article-title":"Transcriptional regulation by cyclic AMP","volume":"66","author":"Montminy","year":"1997","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.bbrc.2004.12.023_bib29","first-page":"643","volume":"vol. 3","author":"Coleman","year":"1989"},{"key":"10.1016\/j.bbrc.2004.12.023_bib30","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0014-2999(97)01383-6","article-title":"Molecular cloning and characterization of the four rat prostagladin E2 prostanoid receptor subtypes","volume":"340","author":"Boie","year":"1997","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bbrc.2004.12.023_bib31","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/S0168-8278(99)80006-3","article-title":"Differential expression of receptors in hepatocytes, Kupffer cells, sinusoidal endothelial cells and stellate cells of rat liver","volume":"30","author":"Fennekohl","year":"1999","journal-title":"J. Hepatol."},{"key":"10.1016\/j.bbrc.2004.12.023_bib32","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1080\/09629359990306","article-title":"Prostaglandin E2 affects differently the release of inflammatory mediators from resident macrophages by LPS and muramyl tripeptides","volume":"8","author":"Dieter","year":"1999","journal-title":"Mediators Inflamm."},{"key":"10.1016\/j.bbrc.2004.12.023_bib33","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1189\/jlb.71.6.1005","article-title":"Regulation of cyclooxygenase-2 by nitric oxide in activated hepatic macrophages during acute endotoxemia","volume":"71","author":"Ahmad","year":"2002","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.bbrc.2004.12.023_bib34","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1053\/he.2000.7055","article-title":"Induction by interleukin 6 of G(s)-coupled prostaglandin E(2) receptors in rat hepatocytes mediating a prostaglandin E(2)-dependent inhibition of hepatocyte\u2019s acute phase response","volume":"31","author":"Fennekohl","year":"2000","journal-title":"Hepatology"},{"key":"10.1016\/j.bbrc.2004.12.023_bib35","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1111\/j.1432-1033.1988.tb13886.x","article-title":"Pertussis toxin abolishes the inhibitory effects of prostaglandins E1, E2, I2 and F2 alpha on hormone-induced cAMP accumulation in cultured hepatocytes","volume":"172","author":"Melien","year":"1988","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.bbrc.2004.12.023_bib36","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1046\/j.1471-4159.2001.00577.x","article-title":"Potentiation of PGE2-mediated cAMP production during neuronal differentiation of human neuroblastoma SK-N-BE(2)C cells","volume":"79","author":"Choi","year":"2001","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbrc.2004.12.023_bib37","doi-asserted-by":"crossref","first-page":"8921","DOI":"10.1073\/pnas.1533221100","article-title":"Inhibition of apoptosis in normal and transformed intestinal epithelial cells by cAMP through induction of inhibitor of apoptosis protein (IAP)-2","volume":"100","author":"Nishihara","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2004.12.023_bib38","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1038\/sj.gt.3301246","article-title":"Baculovirus vectors repress phenobarbital-mediated gene induction and stimulate cytokine expression in primary cultures of rat hepatocytes","volume":"7","author":"Beck","year":"2000","journal-title":"Gene Ther."},{"key":"10.1016\/j.bbrc.2004.12.023_bib39","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1006\/abbi.1998.0754","article-title":"Evidence for involvement of cAMP-dependent pathway in the phenobarbital-induced expression of a novel hamster cytochrome P450, CYP3A31","volume":"356","author":"Bani","year":"1998","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bbrc.2004.12.023_bib40","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/sj.bjp.0701367","article-title":"Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells","volume":"122","author":"Kiriyama","year":"1997","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bbrc.2004.12.023_bib41","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1476-5381.1986.tb10155.x","article-title":"Characterization of prostanoid relaxant\/inhibitory receptors (psi) using a highly selective agonist, TR4979","volume":"87","author":"Gardiner","year":"1986","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bbrc.2004.12.023_bib42","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1146\/annurev.bi.56.070187.003151","article-title":"G-proteins: transducers of receptor-generated signals","volume":"56","author":"Gilman","year":"1987","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.bbrc.2004.12.023_bib43","doi-asserted-by":"crossref","first-page":"27783","DOI":"10.1016\/S0021-9258(18)46850-0","article-title":"Biochemical diversity of cAMP-dependent transcription of steroid hydroxylase genes in the adrenal cortex","volume":"269","author":"Waterman","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2004.12.023_bib44","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1006\/abbi.1999.1351","article-title":"P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR","volume":"369","author":"Waxman","year":"1999","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bbrc.2004.12.023_bib45","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1089\/104454904322759894","article-title":"Repression of CAR-mediated transactivation of CYP2B1 genes by orphan nuclear receptor, short heterodimer partner (SHP)","volume":"23","author":"Yangjin","year":"2004","journal-title":"DNA and Cell Biol."},{"key":"10.1016\/j.bbrc.2004.12.023_bib46","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1124\/mol.58.6.1441","article-title":"Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: consequences on cytochrome P450 gene regulation","volume":"58","author":"Pascussi","year":"2000","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.bbrc.2004.12.023_bib47","doi-asserted-by":"crossref","first-page":"6043","DOI":"10.1074\/jbc.274.10.6043","article-title":"The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene","volume":"274","author":"Sueyoshi","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2004.12.023_bib48","doi-asserted-by":"crossref","first-page":"6318","DOI":"10.1128\/MCB.19.9.6318","article-title":"Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of CYP2B gene","volume":"19","author":"Kawamoto","year":"1999","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbrc.2004.12.023_bib49","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1023\/A:1026702615125","article-title":"Regulation of phenobarbital-induction of CYP2B and CYP3A genes in rat cultured hepatocytes: involvement of several serine\/threonine protein kinases and phosphatases","volume":"16","author":"Joannard","year":"2000","journal-title":"Cell Biol. Toxicol."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X04028128?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X04028128?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,30]],"date-time":"2023-04-30T23:17:28Z","timestamp":1682896648000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X04028128"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,2]]}},"alternative-id":["S0006291X04028128"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2004.12.023","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2005,2]]}}}