{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T09:52:14Z","timestamp":1774173134365,"version":"3.50.1"},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2005,11]]},"DOI":"10.1016\/j.bbrc.2005.09.074","type":"journal-article","created":{"date-parts":[[2005,9,22]],"date-time":"2005-09-22T11:21:12Z","timestamp":1127388072000},"page":"446-451","source":"Crossref","is-referenced-by-count":5,"title":["Docking protein Gab2 positively regulates glycoprotein VI-mediated platelet activation"],"prefix":"10.1016","volume":"337","author":[{"given":"Qun","family":"Yi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsue","family":"Suzuki-Inoue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Asazuma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steve P.","family":"Watson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukio","family":"Ozaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2005.09.074_bib1","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1182\/blood.V93.6.1809.406k35_1809_1816","article-title":"Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors","volume":"93","author":"Nishida","year":"1999","journal-title":"Blood"},{"key":"10.1016\/j.bbrc.2005.09.074_bib2","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1111\/j.1349-7006.2003.tb01396.x","article-title":"The role of Gab family scaffolding adapter proteins in the signal transduction of cytokine and growth factor receptors","volume":"94","author":"Nishida","year":"2003","journal-title":"Cancer Sci."},{"key":"10.1016\/j.bbrc.2005.09.074_bib3","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/S1097-2765(00)80288-9","article-title":"Cloning of p97\/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation","volume":"2","author":"Gu","year":"1998","journal-title":"Mol. Cell"},{"key":"10.1016\/j.bbrc.2005.09.074_bib4","doi-asserted-by":"crossref","first-page":"7109","DOI":"10.1128\/MCB.20.19.7109-7120.2000","article-title":"New role for Shc in activation of the phosphatidylinositol 3-kinase\/Akt pathway","volume":"20","author":"Gu","year":"2000","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbrc.2005.09.074_bib5","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1038\/35084076","article-title":"Essential role for Gab2 in the allergic response","volume":"412","author":"Gu","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2005.09.074_bib6","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1083\/jcb.200212158","article-title":"Critical role for scaffolding adapter Gab2 in Fc gamma R-mediated phagocytosis","volume":"161","author":"Gu","year":"2003","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bbrc.2005.09.074_bib7","doi-asserted-by":"crossref","first-page":"4158","DOI":"10.4049\/jimmunol.165.8.4158","article-title":"Cutting edge: gab2 mediates an inhibitory phosphatidylinositol 3\u2032-kinase pathway in T cell antigen receptor signaling","volume":"165","author":"Pratt","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.bbrc.2005.09.074_bib8","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1038\/ni817","article-title":"Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation","volume":"3","author":"Parravicin","year":"2002","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.bbrc.2005.09.074_bib9","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1182\/blood.V99.5.1866","article-title":"Requirement of Gab2 for mast cell development and KitL\/c-Kit signaling","volume":"99","author":"Nishida","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.bbrc.2005.09.074_bib10","doi-asserted-by":"crossref","first-page":"2515","DOI":"10.1128\/MCB.23.7.2515-2529.2003","article-title":"Gads\/Grb2-mediated association with LAT is critical for the inhibitory function of Gab2 in T cells","volume":"23","author":"Yamasaki","year":"2003","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbrc.2005.09.074_bib11","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/S0301-472X(01)00623-3","article-title":"Role of phosphatidylinositol-3 kinase and its association with Gab1 in thrombopoietin-mediated up-regulation of platelet function","volume":"29","author":"Kojima","year":"2001","journal-title":"Exp. Hematol."},{"key":"10.1016\/j.bbrc.2005.09.074_bib12","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1172\/JCI8944","article-title":"More pieces of the platelet activation puzzle slide into place","volume":"104","author":"Brass","year":"1999","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbrc.2005.09.074_bib13","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1055\/s-0037-1615849","article-title":"Signaling through platelet integrin alpha IIb beta 3: inside-out, outside-in, and sideways","volume":"82","author":"Shattil","year":"1999","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.bbrc.2005.09.074_bib14","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/S0167-5699(98)01267-5","article-title":"Collagen receptor signalling in platelets: extending the role of the ITAM","volume":"19","author":"Watson","year":"1998","journal-title":"Immunol. Today"},{"key":"10.1016\/j.bbrc.2005.09.074_bib15","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1182\/blood-2002-12-3882","article-title":"Platelet\u2013collagen interaction: is GPVI the central receptor?","volume":"102","author":"Nieswandt","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.bbrc.2005.09.074_bib16","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.1093\/emboj\/16.9.2333","article-title":"The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen","volume":"16","author":"Poole","year":"1997","journal-title":"EMBO J."},{"key":"10.1016\/j.bbrc.2005.09.074_bib17","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1084\/jem.188.2.267","article-title":"Physical and functional association of the Src family kinases Fyn and Lyn with the collagen receptor glycoprotein VI\u2013Fc receptor gamma chain complex on human platelets","volume":"188","author":"Ezumi","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.bbrc.2005.09.074_bib18","doi-asserted-by":"crossref","first-page":"2120","DOI":"10.1093\/emboj\/20.9.2120","article-title":"Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen","volume":"20","author":"Nieswandt","year":"2001","journal-title":"EMBO J."},{"key":"10.1016\/j.bbrc.2005.09.074_bib19","doi-asserted-by":"crossref","first-page":"8326","DOI":"10.1128\/MCB.19.12.8326","article-title":"LAT is required for tyrosine phosphorylation of phospholipase cgamma2 and platelet activation by the collagen receptor GPVI","volume":"19","author":"Pasquet","year":"1999","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbrc.2005.09.074_bib20","doi-asserted-by":"crossref","first-page":"5963","DOI":"10.1074\/jbc.274.9.5963","article-title":"Tyrosine phosphorylation of SLP-76 is downstream of Syk following stimulation of the collagen receptor in platelets","volume":"274","author":"Gross","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2005.09.074_bib21","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1042\/bj3110471","article-title":"Syk interacts with tyrosine-phosphorylated proteins in human platelets activated by collagen and cross-linking of the Fc gamma-IIA receptor","volume":"311","author":"Yanaga","year":"1995","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbrc.2005.09.074_bib22","doi-asserted-by":"crossref","first-page":"33427","DOI":"10.1074\/jbc.M001439200","article-title":"Interaction of linker for activation of T cells with multiple adapter proteins in platelets activated by the glycoprotein VI-selective ligand, convulxin","volume":"275","author":"Asazuma","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2005.09.074_bib23","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1042\/bj20020335","article-title":"Differential effects of reduced glycoprotein VI levels on activation of murine platelets by glycoprotein VI ligands","volume":"368","author":"Snell","year":"2002","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbrc.2005.09.074_bib24","doi-asserted-by":"crossref","first-page":"37651","DOI":"10.1074\/jbc.M311985200","article-title":"Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker","volume":"279","author":"Humphries","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2005.09.074_bib25","doi-asserted-by":"crossref","first-page":"9986","DOI":"10.1128\/MCB.24.22.9986-9999.2004","article-title":"Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2","volume":"24","author":"Kim","year":"2004","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbrc.2005.09.074_bib26","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1182\/blood.V99.7.2351","article-title":"Role of the docking protein Gab2 in beta(1)-integrin signaling pathway-mediated hematopoietic cell adhesion and migration","volume":"99","author":"Yu","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.bbrc.2005.09.074_bib27","doi-asserted-by":"crossref","first-page":"8497","DOI":"10.1074\/jbc.M312575200","article-title":"Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factor","volume":"279","author":"Ren","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2005.09.074_bib28","doi-asserted-by":"crossref","first-page":"53955","DOI":"10.1074\/jbc.M410355200","article-title":"Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen","volume":"279","author":"Pearce","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2005.09.074_bib29","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1111\/j.1538-7836.2005.01429.x","article-title":"GPVI and integrin alphaIIbbeta3 signaling in platelets","volume":"3","author":"Watson","year":"2005","journal-title":"J. Thromb. Haemost."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X05021030?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X05021030?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,9]],"date-time":"2020-04-09T20:51:45Z","timestamp":1586465505000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X05021030"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["S0006291X05021030"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2005.09.074","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2005,11]]}}}