{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T11:34:11Z","timestamp":1790940851970,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2006,1]]},"DOI":"10.1016\/j.bbrc.2005.11.046","type":"journal-article","created":{"date-parts":[[2005,11,17]],"date-time":"2005-11-17T07:16:37Z","timestamp":1132211797000},"page":"569-576","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":63,"title":["Phthalocyanine-mediated photodynamic therapy induces cell death and a G0\/G1 cell cycle arrest in cervical cancer cells"],"prefix":"10.1016","volume":"339","author":[{"given":"S.L.","family":"Haywood-Small","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.I.","family":"Vernon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Griffiths","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Schofield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.B.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2005.11.046_bib1","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S1470-2045(04)01529-3","article-title":"The present and future role of photodynamic therapy in cancer treatment","volume":"5","author":"Brown","year":"2004","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.bbrc.2005.11.046_bib2","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1562\/0031-8655(2001)074<0656:THOPAP>2.0.CO;2","article-title":"The history of photodetection and photodynamic therapy","volume":"74","author":"Ackroyd","year":"2001","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.bbrc.2005.11.046_bib3","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S1359-6446(99)01412-9","article-title":"Photodynamic therapeutics: basic principles and clinical applications","volume":"4","author":"Sharman","year":"1999","journal-title":"Drug Discov. Today"},{"key":"10.1016\/j.bbrc.2005.11.046_bib4","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1080\/09546630310012127","article-title":"Photosensitizers for photodynamic therapy of cutaneous disease","volume":"14","author":"Stapleton","year":"2003","journal-title":"J. Dermatol. Treat."},{"key":"10.1016\/j.bbrc.2005.11.046_bib5","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1074\/jbc.M205219200","article-title":"Domain-dependent photodamage to Bcl-2, A membrane anchorage region is needed to form the target of phthalocyanine photosensitization","volume":"278","author":"Usuda","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2005.11.046_bib6","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jphotobiol.2003.11.002","article-title":"9-Hydroxypheophorbide alpha-induced apoptotic death of MCF-7 breast cancer cells is mediated by c-Jun N-terminal kinase activation","volume":"73","author":"Choi","year":"2004","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.bbrc.2005.11.046_bib7","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/1011-1344(95)07250-0","article-title":"Apoptosis of mouse MS-2 fibrosarcoma cells induced by photodynamic therapy with Zn(II)\u2013Phthalocyanine","volume":"33","author":"Zhou","year":"1996","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.bbrc.2005.11.046_bib8","doi-asserted-by":"crossref","first-page":"6977","DOI":"10.1073\/pnas.95.12.6977","article-title":"Photodynamic therapy results in induction of WAF1\/CIP1\/p21 leading to cell cycle arrest and apoptosis","volume":"95","author":"Ahmad","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2005.11.046_bib9","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1038\/sj.bjc.6601298","article-title":"Bax is essential for mitochondrion-mediated apoptosis but not for cell death caused by photodynamic therapy","volume":"89","author":"Chiu","year":"2003","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.bbrc.2005.11.046_bib10","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.jphotobiol.2003.07.007","article-title":"Early apoptotic features of K562 cell death induced by 5-aminolaevulinic acid-based photodynamic therapy","volume":"73","author":"Ku\u017eelov\u00e1","year":"2004","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.bbrc.2005.11.046_bib11","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1054\/bjoc.2001.1795","article-title":"Differential cell death response to photodynamic therapy is dependent on dose and cell type","volume":"84","author":"Wyld","year":"2001","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.bbrc.2005.11.046_bib12","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1038\/nrc1071","article-title":"Photodynamic therapy for cancer","volume":"3","author":"Dolmans","year":"2003","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.bbrc.2005.11.046_bib13","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1111\/j.1751-1097.1997.tb08581.x","article-title":"The role of subcellular localization in initiation of apoptosis by photodynamic therapy","volume":"65","author":"Kessel","year":"1997","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.bbrc.2005.11.046_bib14","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1093\/jnci\/82.13.1107","article-title":"New colorimetric cytotoxicity assay for anticancer-drug screening","volume":"82","author":"Skehan","year":"1990","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.bbrc.2005.11.046_bib15","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1562\/0031-8655(2000)072<0114:SLOMMA>2.0.CO;2","article-title":"Subcellular localization of merocyanine 540 (MC540) and induction of apoptosis in murine myeloid leukemia cells","volume":"72","author":"Chen","year":"2000","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.bbrc.2005.11.046_bib16","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1111\/j.1751-1097.1997.tb08577.x","article-title":"The subcellular localization of Zn(II) phthalocyanines and their redistribution on exposure to light","volume":"65","author":"Wood","year":"1997","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.bbrc.2005.11.046_bib17","first-page":"101","article-title":"Association of ceramide accumulation with photodynamic treatment-induced cell death","volume":"68","author":"Separovic","year":"1998","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.bbrc.2005.11.046_bib18","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1111\/j.1365-2133.2004.06053.x","article-title":"Cyclooxygenase-2 is a possible target of treatment approach in conjunction with photodynamic therapy for various disorders in skin and oral cavity","volume":"151","author":"Akita","year":"2004","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.bbrc.2005.11.046_bib19","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1562\/0031-8655(2000)0710201TROTPT2.0.CO2","article-title":"The role of the p53 suppressor in the response of human cells to photofrin-mediated photodynamic therapy","volume":"71","author":"Tong","year":"2000","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.bbrc.2005.11.046_bib20","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1111\/j.1751-1097.1996.tb02440.x","article-title":"Apoptosis or necrosis following photofrin photosensitization: influence of the incubation protocol","volume":"64","author":"Dellinger","year":"1996","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.bbrc.2005.11.046_bib21","first-page":"87","article-title":"Apoptosis versus necrosis: which should be the aim of cancer therapy?","volume":"221","author":"Kiaris","year":"1999","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"10.1016\/j.bbrc.2005.11.046_bib22","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/00001813-199502000-00014","article-title":"Comparison of sulforhodamine B, tetrazolium and clonogenic assays for in vitro radiosensitivity testing in human ovarian cell lines","volume":"6","author":"Griffon","year":"1995","journal-title":"Anticancer Drugs"},{"key":"10.1016\/j.bbrc.2005.11.046_bib23","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1111\/j.1751-1097.1999.tb08150.x","article-title":"The mode of cell death induced by photodynamic therapy depends on cell density","volume":"70","author":"Dahle","year":"1999","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.bbrc.2005.11.046_bib24","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1054\/drup.2001.0213","article-title":"If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumour cells","volume":"4","author":"Roninson","year":"2001","journal-title":"Drug Resist. Updat."},{"key":"10.1016\/j.bbrc.2005.11.046_bib25","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1038\/sj.onc.1202493","article-title":"Involvement of retinoblastoma (Rb) and E2F transcription factors during photodynamic therapy of human epidermoid carcinoma cells A431","volume":"18","author":"Ahmad","year":"1999","journal-title":"Oncogene"},{"key":"10.1016\/j.bbrc.2005.11.046_bib26","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1111\/j.1751-1097.1987.tb07384.x","article-title":"Biological activities of phthalocyanines-VI. Photoxidation of l-tryptophan by selectively sulfonated gallium phthalocyanines: singlet oxygen yields and effect of aggregation","volume":"45","author":"Wagner","year":"1987","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.bbrc.2005.11.046_bib27","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/0020-711X(92)90200-K","article-title":"Distribution of tetrapyrrole photosensitizers among human plasma proteins","volume":"24","author":"Kongshaug","year":"1992","journal-title":"Int. J. Biochem."},{"key":"10.1016\/j.bbrc.2005.11.046_bib28","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1089\/clm.1996.14.329","article-title":"Induction of tumour immunity by photodynamic therapy","volume":"14","author":"Korbelik","year":"1996","journal-title":"J. Clin. Laser Med. Surg."},{"key":"10.1016\/j.bbrc.2005.11.046_bib29","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1038\/sj.bjc.6690557","article-title":"Water-soluble aluminium phthalocyanine-polymer conjugates for PDT: photodynamic activities and pharmacokinetics in tumour-bearing mice","volume":"80","author":"Brasseur","year":"1999","journal-title":"Br. J. Cancer"}],"updated-by":[{"DOI":"10.1016\/j.bbrc.2006.01.001","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2006,3,10]],"date-time":"2006-03-10T00:00:00Z","timestamp":1141948800000}}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X05025738?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X05025738?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T10:20:19Z","timestamp":1757758819000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X05025738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["S0006291X05025738"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2005.11.046","relation":{"erratum":[{"id-type":"doi","id":"10.1016\/j.bbrc.2006.01.001","asserted-by":"object"}]},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2006,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Phthalocyanine-mediated photodynamic therapy induces cell death and a G0\/G1 cell cycle arrest in cervical cancer cells","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2005.11.046","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}