{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T05:54:18Z","timestamp":1789710858957,"version":"4.0.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T00:00:00Z","timestamp":1141171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2006,3]]},"DOI":"10.1016\/j.bbrc.2006.01.123","type":"journal-article","created":{"date-parts":[[2006,2,4]],"date-time":"2006-02-04T10:52:41Z","timestamp":1139050361000},"page":"323-329","source":"Crossref","is-referenced-by-count":74,"title":["Structural insights into the catalytic mechanism of sphingomyelinases D and evolutionary relationship to glycerophosphodiester phosphodiesterases"],"prefix":"10.1016","volume":"342","author":[{"given":"M\u00e1rio T.","family":"Murakami","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matheus","family":"Freitas Fernandes-Pedrosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia A.","family":"de Andrade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azat","family":"Gabdoulkhakov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Betzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise V.","family":"Tambourgi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raghuvir K.","family":"Arni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2006.01.123_bib1","doi-asserted-by":"crossref","first-page":"10833","DOI":"10.1074\/jbc.C300563200","article-title":"Spider and bacterial sphingomyelinases D target cellular lysophosphatidic acid receptors by hydrolyzing lysophosphatidylcholine","volume":"279","author":"Van Meeteren","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2006.01.123_bib2","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0014-5793(04)00211-X","article-title":"Ceramide-1-phosphate: a novel regulator of cell activation","volume":"562","author":"Gomez-Munoz","year":"2004","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbrc.2006.01.123_bib3","doi-asserted-by":"crossref","first-page":"20555","DOI":"10.1074\/jbc.R400013200","article-title":"Lysophospholipid G protein-coupled receptors","volume":"279","author":"Anliker","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2006.01.123_bib4","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1002\/bies.20081","article-title":"The ins and outs of lysophosphatidic acid signaling","volume":"26","author":"Moolenaar","year":"2004","journal-title":"BioEssays"},{"key":"10.1016\/j.bbrc.2006.01.123_bib5","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1097\/00000441-199210000-00008","article-title":"Loxoscelism","volume":"304","author":"Futrell","year":"1992","journal-title":"Am. J. Med. Sci."},{"key":"10.1016\/j.bbrc.2006.01.123_bib6","doi-asserted-by":"crossref","first-page":"13658","DOI":"10.1074\/jbc.M412437200","article-title":"Structural basis for metal ion coordination and the catalytic mechanism of sphingomyelinases D","volume":"280","author":"Murakami","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2006.01.123_bib7","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/S0006-291X(02)02521-4","article-title":"Molecular cloning and expression of a functional dermonecrotic and hemolytic factor from Loxosceles laeta venom","volume":"298","author":"Fernandes-Pedrosa","year":"2002","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2006.01.123_bib8","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1107\/S0021889895007047","article-title":"CRYSOL\u2014a Program to evaluate X-ray solution scattering of biological macromolecules from atomic coordinates","volume":"28","author":"Svergun","year":"1995","journal-title":"J. Appl. Crystallogr."},{"key":"10.1016\/j.bbrc.2006.01.123_bib9","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0076-6879(97)76066-X","article-title":"Processing of X-ray diffraction data collection in oscillation mode","volume":"276","author":"Otwinowski","year":"1997","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.bbrc.2006.01.123_bib10","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1107\/S0907444998006684","article-title":"SFCHECK: a unified set of procedures for evaluating the quality of macromolecular structure-factor data and their agreement with the atomic model","volume":"55","author":"Vaguine","year":"1999","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.bbrc.2006.01.123_bib11","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/S0076-6879(97)76068-3","article-title":"Detecting and overcoming crystal twinning","volume":"276","author":"Yeates","year":"1997","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.bbrc.2006.01.123_bib12","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1107\/S0108767393007597","article-title":"AMoRe: an automated package for molecular replacement","volume":"50","author":"Navaza","year":"1994","journal-title":"Acta Crystallogr. sect. A"},{"key":"10.1016\/j.bbrc.2006.01.123_bib13","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1107\/S0907444996012255","article-title":"Refinement of macromolecular structures by the maximum-likelihood method","volume":"53","author":"Murshudov","year":"1997","journal-title":"Acta Crystallogr. Sect. D"},{"key":"10.1016\/j.bbrc.2006.01.123_bib14","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/0076-6879(85)15014-7","article-title":"Interactive computer graphics: FRODO","volume":"115","author":"Jones","year":"1985","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.bbrc.2006.01.123_bib15","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1107\/S0907444904019158","article-title":"Coot: model-building tools for molecular graphics","volume":"60","author":"Emsley","year":"2004","journal-title":"Acta Crystallogr. Sect. D"},{"key":"10.1016\/j.bbrc.2006.01.123_bib16","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1038\/8263","article-title":"Automated protein model building combined with iterative structure refinement","volume":"6","author":"Perrakis","year":"1999","journal-title":"Nat. Struct. Biol."},{"key":"10.1016\/j.bbrc.2006.01.123_bib17","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1107\/S0021889892009944","article-title":"PROCHECK: a program to check the stereochemical quality of protein structures","volume":"26","author":"Laskowski","year":"1993","journal-title":"J. Appl. Crystallogr."},{"key":"10.1016\/j.bbrc.2006.01.123_bib18","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1006\/jmbi.1993.1626","article-title":"Comparative protein modelling by satisfaction of spatial restraints","volume":"234","author":"Sali","year":"1993","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bbrc.2006.01.123_bib19","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1110\/ps.9.9.1753","article-title":"Modeling of loops in protein structures","volume":"9","author":"Fiser","year":"2000","journal-title":"Protein Sci."},{"key":"10.1016\/j.bbrc.2006.01.123_bib20","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0022-2836(63)80023-6","article-title":"Stereochemistry of polypeptide chain configurations","volume":"7","author":"Ramachandran","year":"1963","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bbrc.2006.01.123_bib21","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/0035-9203(82)90222-X","article-title":"Loxoscelism in the Transvaal. South Africa","volume":"76","author":"Newlands","year":"1982","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.bbrc.2006.01.123_bib22","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.molimm.2004.03.027","article-title":"Molecular cloning, expression, function and immunoreactivities of members of a gene family of sphingomyelinases from Loxosceles venom glands","volume":"41","author":"Tambourgi","year":"2004","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.bbrc.2006.01.123_bib23","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1093\/bioinformatics\/bti811","article-title":"Lateral gene transfer of a dermonecrotic toxin between spiders and bacteria","volume":"22","author":"Cordes","year":"2005","journal-title":"Bioinformatics"},{"key":"10.1016\/j.bbrc.2006.01.123_bib24","doi-asserted-by":"crossref","first-page":"35011","DOI":"10.1074\/jbc.M506800200","article-title":"Crystal structure of SmcL, a bacterial neutral sphingomyelinase C from Listeria","volume":"280","author":"Openshaw","year":"2005","journal-title":"J. Biol. Chem."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X06001665?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X06001665?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,18]],"date-time":"2019-01-18T12:52:48Z","timestamp":1547815968000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X06001665"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,3]]}},"alternative-id":["S0006291X06001665"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2006.01.123","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2006,3]]}}}